Published in Diabetes on March 01, 1986
Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest (1994) 2.09
Indirect sensing of insulin-induced hypoglycaemia by the carotid body in the rat. J Physiol (2004) 1.58
Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia. Proc Natl Acad Sci U S A (1994) 1.15
Peripheral and central glucose sensing in hypoglycemic detection. Physiology (Bethesda) (2014) 0.81
Glucose sensing by carotid body glomus cells: potential implications in disease. Front Physiol (2014) 0.81
Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas. J Clin Invest (1986) 0.79
2. Hypoglycemia Detection. Transl Endocrinol Metab (2012) 0.78
Quantitative estimation of insulin sensitivity. Am J Physiol (1979) 7.37
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet (1992) 6.28
Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest (1981) 5.82
Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes (1993) 5.70
Assessment of insulin sensitivity in vivo. Endocr Rev (1985) 4.21
Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care (1998) 3.99
MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed (1986) 3.54
Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes (1987) 2.95
Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest (1987) 2.81
Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study. JAMA (1998) 2.56
Insulin transport across capillaries is rate limiting for insulin action in dogs. J Clin Invest (1989) 2.32
Third-trimester rudimentary horn pregnancy. A case report. J Reprod Med (1998) 2.23
Outcome of lamivudine resistant hepatitis B virus infection in the liver transplant recipient. Gut (2000) 2.16
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am J Physiol (1994) 2.13
British HIV Association guidelines for the routine investigation and monitoring of adult HIV-1-infected individuals 2011. HIV Med (2012) 2.05
Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes (1993) 2.03
Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci U S A (1999) 1.91
Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes (1995) 1.91
Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr. Am J Physiol Endocrinol Metab (2001) 1.86
Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators. Hum Hered (1999) 1.76
A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance. Insulin Resistance Atherosclerosis Study. Diabetes (1994) 1.73
Association between pre-pregnancy obesity and the risk of cesarean delivery. Obstet Gynecol (1997) 1.72
Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab (1990) 1.71
Role of glucose effectiveness in the determination of glucose tolerance. Diabetes Care (1996) 1.68
Quantitative estimation of beta cell sensitivity to glucose in the intact organism: a minimal model of insulin kinetics in the dog. Diabetes (1980) 1.67
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest (1993) 1.67
Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diabetes Care (1994) 1.67
Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes (2000) 1.63
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. J Clin Invest (1996) 1.60
Dietary fat and insulin sensitivity in a triethnic population: the role of obesity. The Insulin Resistance Atherosclerosis Study (IRAS) Am J Clin Nutr (1997) 1.59
Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects. Diabetes (1992) 1.56
Modified protocols improve insulin sensitivity estimation using the minimal model. Am J Physiol (1987) 1.54
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes (2000) 1.52
Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab (1997) 1.48
Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes. Am J Obstet Gynecol (1990) 1.48
Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. J Clin Invest (1996) 1.45
The clinical spectrum of respiratory syncytial virus disease in The Gambia. Pediatr Infect Dis J (1998) 1.45
Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased beta-cell function. J Clin Endocrinol Metab (1985) 1.43
A randomized multicenter trial assessing a home uterine activity monitoring device used in the absence of daily nursing contact. Am J Obstet Gynecol (1995) 1.43
Ethnic differences in carotid wall thickness. The Insulin Resistance Atherosclerosis Study. Stroke (1996) 1.42
Insulin sensitivity and acute insulin response in African-Americans, non-Hispanic whites, and Hispanics with NIDDM: the Insulin Resistance Atherosclerosis Study. Diabetes (1997) 1.42
Amnioinfusion and the intrauterine prevention of meconium aspiration. Am J Obstet Gynecol (1994) 1.42
Female alloimmunization with antibodies known to cause hemolytic disease. Obstet Gynecol (1997) 1.39
Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes (1997) 1.36
The modified minimal model: application to measurement of insulin sensitivity in children. J Clin Endocrinol Metab (1990) 1.35
Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. Am J Physiol (1990) 1.31
Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am J Physiol (1999) 1.30
The insulin sensitivity index in nondiabetic man. Correlation between clamp-derived and IVGTT-derived values. Diabetes (1986) 1.30
Peripheral effects of insulin dominate suppression of fasting hepatic glucose production. Am J Physiol (1990) 1.29
Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps. Diabetes (1988) 1.28
Insulin sensitivity from meal tolerance tests in normal subjects: a minimal model index. J Clin Endocrinol Metab (2000) 1.25
Influence of total vs. visceral fat on insulin action and secretion in African American and white children. Obes Res (2001) 1.25
Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. Am J Physiol Endocrinol Metab (2000) 1.24
Physical activity, obesity, and diabetes in pregnancy. Am J Epidemiol (1997) 1.23
Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest (1997) 1.22
Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process. J Clin Invest (1996) 1.21
Intraportal glucose infusion matched to oral glucose absorption. Lack of evidence for "gut factor" involvement in hepatic glucose storage. Diabetes (1982) 1.20
Minimal modeling, partition analysis, and the estimation of insulin sensitivity. Fed Proc (1980) 1.18
High pre-treatment serum hepatitis B virus titre predicts failure of lamivudine prophylaxis and graft re-infection after liver transplantation. J Hepatol (1999) 1.17
The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences. Diabetes (2001) 1.17
Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia. Proc Natl Acad Sci U S A (1994) 1.15
Dynamics of glucose autoregulation in the isolated, blood-perfused canine liver. Am J Physiol (1974) 1.15
Glucose tolerance and insulin action in rats with renovascular hypertension. Hypertension (1991) 1.15
Diminished insulin sensitivity and increased insulin response in nonobese, nondiabetic Mexican Americans. Metabolism (1990) 1.14
Integrated control of hepatic glucose metabolism. Fed Proc (1977) 1.12
Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes (1991) 1.12
The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects. Diabetes (1994) 1.12
Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport. J Clin Invest (1991) 1.12
Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. Diabetes (1994) 1.12
Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes (1989) 1.09
Importance of glucose per se to intravenous glucose tolerance. Comparison of the minimal-model prediction with direct measurements. Diabetes (1985) 1.09
Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes (2000) 1.09
Optimal segments: a method for smoothing tracer data to calculate metabolic fluxes. Am J Physiol (1983) 1.09
A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). Diabetologia (2009) 1.08
Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues. Diabetes (1992) 1.08
Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia (2004) 1.07
Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic glucose and stimulate counter-regulatory hormones. Diabetologia (2005) 1.07
Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study. Int J Obes (Lond) (2005) 1.06
Exercise in gestational diabetes. An optional therapeutic approach? Diabetes (1991) 1.06
Angiotensin II induces insulin resistance independent of changes in interstitial insulin. Am J Physiol (1999) 1.06
Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion. Am J Physiol (1998) 1.05
Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose. Am J Physiol (1994) 1.04
Carotid artery atherosclerosis in type-2 diabetic and nondiabetic subjects with and without symptomatic coronary artery disease (The Insulin Resistance Atherosclerosis Study). Am J Cardiol (2000) 1.03
Tocolysis with advanced cervical dilatation. Obstet Gynecol (2000) 1.03
Recent advances in understanding maternal and fetal responses to exercise. Med Sci Sports Exerc (1993) 1.02
Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study. Diabetologia (2009) 1.01
Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. Am J Epidemiol (1997) 1.01
The pilot gland approach to the study of insulin secretory dynamics. Recent Prog Horm Res (1971) 1.01
Relationship of insulin clearance and secretion to insulin sensitivity in non-diabetic Mexican Americans. Eur J Clin Invest (1992) 1.01
Cardiovascular and catecholamine changes after administration of pancuronium in distressed neonates. Pediatrics (1985) 1.00
Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. Diabetologia (2009) 1.00
Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph. Diabetes (1994) 1.00
The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs. Diabetes (1994) 1.00
Linkage disequilibrium between microsatellite markers extends beyond 1 cM on chromosome 20 in Finns. Genome Res (2001) 0.99
Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study. Diabetologia (2005) 0.99
Prenatal HIV screening in pregnant women: a medical-legal review. Birth (1997) 0.98
Repeatability of insulin sensitivity and glucose effectiveness from the minimal model. Implications for study design. Diabetes (1994) 0.97
Serial salivary estriol to detect an increased risk of preterm birth. Obstet Gynecol (2000) 0.97
Hypoglycemic detection does not occur in the hepatic artery or liver: findings consistent with a portal vein glucosensor locus. Diabetes (2001) 0.96
Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose. J Clin Endocrinol Metab (1990) 0.96