Published in Proc Natl Acad Sci U S A on May 01, 1986
A gene activated by growth factors is related to the oncogene v-jun. Proc Natl Acad Sci U S A (1988) 7.47
Complexity of the early genetic response to growth factors in mouse fibroblasts. Mol Cell Biol (1988) 5.21
A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells. EMBO J (1988) 3.98
c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I. Proc Natl Acad Sci U S A (1988) 3.24
Modification of fos proteins: phosphorylation of c-fos, but not v-fos, is stimulated by 12-tetradecanoyl-phorbol-13-acetate and serum. Mol Cell Biol (1987) 2.40
Repression of c-fos transcription is mediated through p67SRF bound to the SRE. EMBO J (1989) 2.24
Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells. Mol Cell Biol (1988) 2.00
Trans-activation by the c-myb proto-oncogene. Nucleic Acids Res (1989) 1.84
Fos C-terminal mutations block down-regulation of c-fos transcription following serum stimulation. EMBO J (1988) 1.54
Autonomous expression of c-myc in BC3H1 cells partially inhibits but does not prevent myogenic differentiation. Mol Cell Biol (1987) 1.52
A novel target cell for c-fos-induced oncogenesis: development of chondrogenic tumours in embryonic stem cell chimeras. EMBO J (1991) 1.46
An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate. Mol Cell Biol (1989) 1.45
Insulin and growth factor effects on c-fos expression in normal and protein kinase C-deficient 3T3-L1 fibroblasts and adipocytes. Proc Natl Acad Sci U S A (1986) 1.31
Novel Jun- and Fos-related proteins in Drosophila are functionally homologous to enhancer factor AP-1. EMBO J (1988) 1.29
Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos. Proc Natl Acad Sci U S A (1990) 1.24
A short-lived nuclear phosphoprotein encoded by the human ets-2 proto-oncogene is stabilized by activation of protein kinase C. Mol Cell Biol (1988) 1.23
Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter. Mol Cell Biol (1990) 1.20
Requirement of protein co-factor for the DNA-binding function of the human ski proto-oncogene product. Nucleic Acids Res (1990) 1.20
Subnuclear localization of the trans-activating protein of human T-cell leukemia virus type I. J Virol (1988) 1.15
MTrasT24, a metallothionein-ras fusion gene, modulates expression in cultured rat liver cells of two genes associated with in vivo liver cancer. Proc Natl Acad Sci U S A (1988) 1.08
The visna virus long terminal repeat directs expression of a reporter gene in activated macrophages, lymphocytes, and the central nervous systems of transgenic mice. J Virol (1989) 1.04
Adherence-dependent increase in human monocyte PDGF(B) mRNA is associated with increases in c-fos, c-jun, and EGR2 mRNA. J Cell Biol (1990) 1.03
Novel DNA binding specificities of a putative herpesvirus bZIP oncoprotein. J Virol (1996) 1.01
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus) Proc Natl Acad Sci U S A (1996) 1.00
The adenovirus Ela gene induces differentiation of F9 teratocarcinoma cells. Mol Cell Biol (1987) 0.99
Myristylation alters DNA-binding activity and transactivation of FBR (gag-fos) protein. Mol Cell Biol (1991) 0.95
Coupled and uncoupled induction of fos and jun transcription by different second messengers in cells of hematopoietic origin. Nucleic Acids Res (1990) 0.92
Structure of the human TIMP-3 gene and its cell cycle-regulated promoter. Biochem J (1995) 0.92
Raf-1 protein kinase is an integral component of the oncogenic signal cascade shared by epidermal growth factor and platelet-derived growth factor. Mol Cell Biol (1992) 0.91
trans activation of type 1 interferon promoters by simian virus 40 T antigen. Mol Cell Biol (1988) 0.89
Fos and Jun oncogenes transactivate chimeric or native promoters containing AP1/GCN4 binding sites in plant cells. Plant Cell (1990) 0.85
c-fos expression precedes osteogenic differentiation of cartilage cells in vitro. J Cell Biol (1990) 0.85
Revertants of v-fos-transformed rat fibroblasts: suppression of transformation is dominant. Mol Cell Biol (1990) 0.84
A cell mutant that exhibits temperature-dependent sensitivity to transformation by various oncogenes. Mol Cell Biol (1989) 0.84
v-myb does not prevent the expression of c-myb in avian erythroblasts. J Virol (1987) 0.84
Neonatal induction of a nuclear protein that binds to the c-fos enhancer. Proc Natl Acad Sci U S A (1989) 0.80
The malignant conversion step of mouse skin carcinogenesis. Environ Health Perspect (1990) 0.77
Oncogenes and gastrointestinal cancer. Gut (1988) 0.75
Myristylation of FBR v-fos dictates the differentiation pathways in malignant osteosarcoma. J Cell Biol (1996) 0.75
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (1984) 24.45
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc Natl Acad Sci U S A (1982) 20.55
Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature (1985) 9.73
Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells. Science (1984) 9.14
Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein. Nature (1985) 8.36
Transcriptional activation of cloned human beta-globin genes by viral immediate-early gene products. Cell (1983) 7.22
Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat. Science (1985) 6.51
FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. J Virol (1982) 6.11
c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene. Cell (1984) 5.55
Activation of the SV40 late promoter: direct effects of T antigen in the absence of viral DNA replication. Cell (1984) 5.30
Viral and cellular fos proteins: a comparative analysis. Cell (1984) 4.89
Structure of the promoter for chicken alpha 2 type I collagen gene. Proc Natl Acad Sci U S A (1981) 4.89
Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. Science (1984) 4.87
cis and trans activation of globin gene transcription in transient assays. Proc Natl Acad Sci U S A (1983) 4.41
Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation. Cell (1985) 3.81
Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen. Proc Natl Acad Sci U S A (1984) 3.80
Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection. Proc Natl Acad Sci U S A (1984) 3.24
Regulation of heat shock protein 70 gene expression by c-myc. Nature (1984) 3.18
Superinduction of c-fos by nerve growth factor in the presence of peripherally active benzodiazepines. Science (1985) 3.15
Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes. EMBO J (1984) 3.03
Virus induction of osteosarcomas in mice. Science (1966) 2.96
Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes. Nature (1984) 2.34
Rous sarcoma virus encodes a transcriptional activator. Cell (1985) 2.28
A stable bovine papillomavirus hybrid plasmid that expresses a dominant selective trait. Mol Cell Biol (1983) 2.21
Candidate product of the FBJ murine osteosarcoma virus oncogene: characterization of a 55,000-dalton phosphoprotein. J Virol (1982) 2.13
Bovine leukemia virus long terminal repeat: a cell type-specific promoter. Science (1985) 1.93
Regulation of a collagen gene promoter by the product of viral mos oncogene. Nature (1985) 1.85
Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts. J Biol Chem (1985) 1.71
Trans activation of the bovine leukemia virus long terminal repeat in BLV-infected cells. Science (1985) 1.67
Differential expression of c-fos in hematopoietic cells: correlation with differentiation of monomyelocytic cells in vitro. EMBO J (1984) 1.63
FBR murine osteosarcoma virus. II. Nucleotide sequence of the provirus reveals that the genome contains sequences acquired from two cellular genes. Virology (1984) 1.53
Molecular mechanism for the capture and excision of the transforming gene of avian sarcoma virus as suggested by analysis of recombinant clones. J Virol (1980) 1.31
Extended life span and tumorigenicity of nonestablished mouse connective tissue cells transformed by the fos oncogene of FBR-MuSV. Cell (1985) 1.22
Association of collagen with preimplantation and peri-implantation mouse embryos. Dev Biol (1980) 0.91
Evidence for two functional gal promoters in intact Escherichia coli cells. J Biol Chem (1981) 17.42
The E2F transcription factor is a cellular target for the RB protein. Cell (1991) 9.62
Cyclic AMP receptor protein: role in transcription activation. Science (1984) 8.37
Sox9 is required for cartilage formation. Nat Genet (1999) 7.89
SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol (1997) 5.72
Identification of a functional promoter in the long terminal repeat of Rous sarcoma virus. Cell (1980) 5.51
Dual control for transcription of the galactose operon by cyclic AMP and its receptor protein at two interspersed promoters. Cell (1977) 5.29
Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol (1987) 5.25
A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J (1998) 5.15
Structure of the promoter for chicken alpha 2 type I collagen gene. Proc Natl Acad Sci U S A (1981) 4.89
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proc Natl Acad Sci U S A (2001) 4.13
The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell (2001) 4.11
Interaction site of Escherichia coli cyclic AMP receptor protein on DNA of galactose operon promoters. Proc Natl Acad Sci U S A (1979) 3.83
Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts. Proc Natl Acad Sci U S A (1977) 3.80
A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-beta. Cell (1988) 3.72
The collagen gene: evidence for its evolutinary assembly by amplification of a DNA segment containing an exon of 54 bp. Cell (1980) 3.66
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell (1992) 3.64
A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells. J Biol Chem (1996) 3.30
Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic mice. J Cell Biol (1995) 3.16
The family of collagen genes. Annu Rev Biochem (1990) 2.98
Role of the CCAAT-binding protein CBF/NF-Y in transcription. Trends Biochem Sci (1998) 2.71
Nucleotide sequence of the attenuator region of the histidine operon of Escherichia coli K-12. Proc Natl Acad Sci U S A (1978) 2.71
Nucleotide sequence of the operator-promoter region of the galactose operon of Escherichia coli. Proc Natl Acad Sci U S A (1977) 2.57
Unusual methylation pattern of the alpha 2 (l) collagen gene. Cell (1982) 2.36
Unusual location and function of the operator in the Escherichia coli galactose operon. Nature (1979) 2.35
Mutations in the Escherichia coli operon that define two promoters and the binding site of the cyclic AMP receptor protein. J Mol Biol (1982) 2.30
Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer. J Biol Chem (1998) 2.21
Isolation and characterization of overlapping genomic clones covering the chicken alpha 2 (type I) collagen gene. Proc Natl Acad Sci U S A (1980) 2.18
Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Proc Natl Acad Sci U S A (1995) 2.17
Selective activation of transcription by a novel CCAAT binding factor. Science (1988) 2.12
Use of recombinant plasmids to characterize collagen RNAs in normal and transformed chick embryo fibroblasts. J Biol Chem (1979) 2.07
Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene. Proc Natl Acad Sci U S A (1987) 2.07
Correlation between splicing sites within an intron and their sequence complementarity with U1 RNA. Cell (1980) 2.02
E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection. Mol Cell Biol (1992) 2.01
Transforming growth factor beta: biochemistry and roles in embryogenesis, tissue repair and remodeling, and carcinogenesis. Recent Prog Horm Res (1988) 1.99
L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. Osteoarthritis Cartilage (2001) 1.96
Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am J Pathol (1995) 1.95
A CCAAT DNA binding factor consisting of two different components that are both required for DNA binding. J Biol Chem (1988) 1.93
A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice. J Cell Sci (1995) 1.90
Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha. J Biol Chem (2000) 1.86
Regulation of a collagen gene promoter by the product of viral mos oncogene. Nature (1985) 1.85
Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene. J Biol Chem (1995) 1.85
Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. Proc Natl Acad Sci U S A (2000) 1.82
A sequence conserved in both the chicken and mouse alpha 2(I) collagen promoter contains sites sensitive to S1 nuclease. J Biol Chem (1984) 1.81
Effects of transformation on fibronectin gene expression using cloned fibronectin cDNA. J Biol Chem (1981) 1.79
Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts. J Biol Chem (1985) 1.71
The B subunit of the CAAT-binding factor NFY binds the central segment of the Co-activator p300. J Biol Chem (1999) 1.70
Toward understanding SOX9 function in chondrocyte differentiation. Matrix Biol (1998) 1.70
Tissue-specific expression of the mouse alpha 2(I) collagen promoter. Studies in transgenic mice and in tissue culture cells. J Biol Chem (1992) 1.69
Molecuar model of the DNA interaction site for the cyclic AMP receptor protein. Proc Natl Acad Sci U S A (1981) 1.69
Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing. J Biol Chem (1991) 1.67
Construction of a recombinant bacterial plasmid containing pro-alpha 1(I) collagen DNA sequences. J Biol Chem (1980) 1.65
Isolation of genomic DNA clones spanning the entire fibronectin gene. Proc Natl Acad Sci U S A (1983) 1.65
An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes. Mol Cell Biol (1996) 1.64
The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor. Proc Natl Acad Sci U S A (1990) 1.63
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer. Mol Cell Biol (2000) 1.63
Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo. J Biol Chem (1998) 1.61
Transcriptional control of the mouse alpha 2(I) collagen gene: functional deletion analysis of the promoter and evidence for cell-specific expression. Mol Cell Biol (1986) 1.60
Construction of a recombinant bacterial plasmid containing a chick pro-alpha2 collagen gene sequence. Proc Natl Acad Sci U S A (1978) 1.59
Isolation of a cDNA clone encoding rat insulin-like growth factor-II precursor. Nature (1984) 1.58
On the mechanism of action of lac repressor. Nat New Biol (1971) 1.55
Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. Nat Genet (1996) 1.54
Stimulation of lac mRNA synthesis by cyclic AMP in cell free extracts of Escherichia coli. Biochem Biophys Res Commun (1970) 1.51
Purification and molecular cloning of the "A" chain of a rat heteromeric CCAAT-binding protein. Sequence identity with the yeast HAP3 transcription factor. J Biol Chem (1990) 1.49
Three classes of mutations in the A subunit of the CCAAT-binding factor CBF delineate functional domains involved in the three-step assembly of the CBF-DNA complex. Mol Cell Biol (1996) 1.49
Sequence rearrangement and duplication of double stranded fibronectin cDNA probably occurring during cDNA synthesis by AMV reverse transcriptase and Escherichia coli DNA polymerase I. Nucleic Acids Res (1980) 1.48
Identification of the promoter and first exon of the mouse alpha 1 (III) collagen gene. J Biol Chem (1985) 1.48
Specificity of the bacteriophage lambda N gene product (pN): nut sequences are necessary and sufficient for antitermination by pN. Cell (1979) 1.47
Separate binding sites for nuclear factor 1 and a CCAAT DNA binding factor in the mouse alpha 2(I) collagen promoter. J Biol Chem (1987) 1.47
Three different polypeptides are necessary for DNA binding of the mammalian heteromeric CCAAT binding factor. J Biol Chem (1992) 1.47
Regulation or procollagen messenger ribonucleic acid levels in Rous sarcoma virus transformed chick embryo fibroblasts. Biochemistry (1981) 1.46
ATPase activity required for termination of transcription by the Escherichia coli protein factor rho. J Biol Chem (1976) 1.45
Decreased levels of collagen mRNA in rous sarcoma virus-transformed chick embryo fibroblasts. J Biol Chem (1978) 1.44
Transcription of the chicken alpha 2 (Type I) collagen gene by homologous cell-free extracts. J Biol Chem (1982) 1.44
The 5'-terminal nucleotide sequence of galactose messenger ribonucleic acid of Escherichia coli. Proc Natl Acad Sci U S A (1974) 1.44
Isolation and characterization of genomic DNA coding for alpha 2 type I collagen. Nucleic Acids Res (1980) 1.43
Studies on transcription activation by the multimeric CCAAT-binding factor CBF. J Biol Chem (1995) 1.41
Accurate in vitro transcriptional initiation of the chick alpha 2 (Type I) collagen gene. J Biol Chem (1981) 1.41
Identification, nucleotide sequence and expression of the regulatory region of the histidine operon of Escherichia coli K-12. Nucleic Acids Res (1981) 1.41
DNA sequence comparison of the regulatory signals at the 5' end of the mouse and chick alpha 2 type I collagen genes. J Biol Chem (1984) 1.40
Two different negative and one positive regulatory factors interact with a short promoter segment of the alpha 1 (I) collagen gene. J Biol Chem (1990) 1.39
A conserved nucleotide sequence, coding for a segment of the C-propeptide, is found at the same location in different collagen genes. Nucleic Acids Res (1983) 1.37
Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice. Proc Natl Acad Sci U S A (1986) 1.34
In vivo and in vitro detection of the leader RNA of the histidine operon of Escherichia coli K-12. Proc Natl Acad Sci U S A (1981) 1.34
Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family. J Biol Chem (2001) 1.33
Transcription in vitro of bacteriophage lambda 4S RNA: studies on termination and rho protein. Nucleic Acids Res (1977) 1.33
Type X collagen gene expression in mouse chondrocytes immortalized by a temperature-sensitive simian virus 40 large tumor antigen. J Cell Biol (1995) 1.32
Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts. Proc Natl Acad Sci U S A (1996) 1.31
Differential binding of a CCAAT DNA binding factor to the promoters of the mouse alpha 2(I) and alpha 1(III) collagen genes. J Biol Chem (1986) 1.31
Regulation of the expression of genes encoding types I, II, and III collagen during chick embryonic development. J Biol Chem (1983) 1.31
A uniquely conserved regulatory signal is found around the translation initiation site in three different collagen genes. J Biol Chem (1983) 1.30