Published in Proc Natl Acad Sci U S A on December 01, 1983
Intergenic transcription and transinduction of the human beta-globin locus. Genes Dev (1997) 4.30
Discrete elements within the SV40 enhancer region display different cell-specific enhancer activities. EMBO J (1987) 4.28
Association of adenovirus early-region 1A proteins with cellular polypeptides. Mol Cell Biol (1986) 4.14
Promiscuous trans activation of gene expression by an Epstein-Barr virus-encoded early nuclear protein. J Virol (1986) 3.82
Eukaryotic transient expression system dependent on transcription factors and regulatory DNA sequences of vaccinia virus. Proc Natl Acad Sci U S A (1985) 3.61
A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro. EMBO J (1987) 3.45
HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism. Mol Cell Biol (1984) 3.44
Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product. Mol Cell Biol (1986) 3.34
Adenovirus EIIA early promoter: transcriptional control elements and induction by the viral pre-early EIA gene, which appears to be sequence independent. Proc Natl Acad Sci U S A (1985) 3.32
trans Activation of the simian virus 40 late transcription unit by T-antigen. Mol Cell Biol (1985) 2.85
Identification of a factor in HeLa cells specific for an upstream transcriptional control sequence of an EIA-inducible adenovirus promoter and its relative abundance in infected and uninfected cells. Proc Natl Acad Sci U S A (1986) 2.81
Transcription of the human hsp70 gene is induced by serum stimulation. Proc Natl Acad Sci U S A (1985) 2.76
Effects of the position of the simian virus 40 enhancer on expression of multiple transcription units in a single plasmid. Mol Cell Biol (1986) 2.73
Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells. Mol Cell Biol (1986) 2.70
E1A 13S and 12S mRNA products made in Escherichia coli both function as nucleus-localized transcription activators but do not directly bind DNA. Mol Cell Biol (1985) 2.68
Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence. J Virol (1988) 2.67
Analysis of an activatable promoter: sequences in the simian virus 40 late promoter required for T-antigen-mediated trans activation. Mol Cell Biol (1985) 2.55
Regulation of transcription of the adenovirus EII promoter by EIa gene products: absence of sequence specificity. Mol Cell Biol (1984) 2.42
A human parvovirus, adeno-associated virus, as a eucaryotic vector: transient expression and encapsidation of the procaryotic gene for chloramphenicol acetyltransferase. Mol Cell Biol (1984) 2.36
High-level erythroid expression of human alpha-globin genes in transgenic mice. Proc Natl Acad Sci U S A (1989) 2.26
Functional analysis of the transcription control region located within the avian retroviral long terminal repeat. Mol Cell Biol (1985) 2.12
An enhancer element lies 3' to the human A gamma globin gene. EMBO J (1987) 2.11
Human U2 small nuclear RNA genes contain an upstream enhancer. EMBO J (1986) 2.10
Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products. Nucleic Acids Res (1985) 2.04
Partial purification of a nuclear protein that binds to the CCAAT box of the mouse alpha 1-globin gene. Mol Cell Biol (1986) 2.04
Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function. Mol Cell Biol (1985) 2.01
Transcriptional activation encoded by the v-fos gene. Proc Natl Acad Sci U S A (1986) 1.99
Elements required for transcription initiation of the human U2 snRNA gene coincide with elements required for snRNA 3' end formation. EMBO J (1988) 1.97
Nuclear scaffold attachment sites in the human globin gene complexes. EMBO J (1988) 1.97
DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc. Proc Natl Acad Sci U S A (1989) 1.94
Trans activation of plasmid-borne promoters by adenovirus and several herpes group viruses. Nucleic Acids Res (1984) 1.93
Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors. EMBO J (1995) 1.93
A T cell-specific enhancer is located in a DNase I-hypersensitive area at the 3' end of the CD3-delta gene. EMBO J (1988) 1.90
Sequence-independent autoregulation of the adenovirus type 5 E1A transcription unit. Mol Cell Biol (1985) 1.90
Liver-specific expression of hepatitis B virus is determined by the combined action of the core gene promoter and the enhancer. J Virol (1989) 1.88
E1a transactivation of the human HSP70 promoter is mediated through the basal transcriptional complex. Mol Cell Biol (1989) 1.83
Cellular factors that interact with the hepatitis B virus enhancer. Mol Cell Biol (1989) 1.78
Stimulation of the adenovirus E2 promoter by simian virus 40 T antigen or E1A occurs by different mechanisms. Mol Cell Biol (1986) 1.76
Cell type-specific negative regulatory element in the control region of the rat alpha-fetoprotein gene. Proc Natl Acad Sci U S A (1986) 1.70
A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line. Proc Natl Acad Sci U S A (1986) 1.69
Novel metabolism of several beta zero-thalassemic beta-globin mRNAs in the erythroid tissues of transgenic mice. EMBO J (1989) 1.68
Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity. J Virol (1985) 1.67
Control of adenovirus late promoter expression in two human cell lines. Mol Cell Biol (1985) 1.66
Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs. Mol Cell Biol (1993) 1.59
Adenovirus 5 early region 1A host range mutants hr3, hr4, and hr5 contain point mutations which generate single amino acid substitutions. J Virol (1985) 1.53
Interactions between the promoter and first intron are involved in transcriptional control of alpha 1(I) collagen gene expression. Mol Cell Biol (1988) 1.49
Expression of the human beta-globin gene after retroviral transfer into murine erythroleukemia cells and human BFU-E cells. Mol Cell Biol (1988) 1.45
The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element. EMBO J (1990) 1.45
Properties of a mouse ribosomal protein promoter. Proc Natl Acad Sci U S A (1986) 1.42
Activation of the adenovirus and BK virus late promoters: effects of the BK virus enhancer and trans-acting viral early proteins. Mol Cell Biol (1986) 1.40
Transcription control region within the protein-coding portion of adenovirus E1A genes. Mol Cell Biol (1984) 1.36
trans Activation of the simian virus 40 enhancer. Mol Cell Biol (1986) 1.29
An element downstream of the cap site is required for transcription of the gene encoding mouse ribosomal protein L32. Proc Natl Acad Sci U S A (1989) 1.27
Opposite replication polarity of the germ line c-myc gene in HeLa cells compared with that of two Burkitt lymphoma cell lines. Mol Cell Biol (1989) 1.26
Modular structure of the beta-globin and the TK promoters. EMBO J (1984) 1.18
Adenovirus-2 early region IA protein synthesized in Escherichia coli extracts indirectly associates with DNA. EMBO J (1986) 1.17
Adenovirus E1A-mediated regulation of class I MHC expression. EMBO J (1986) 1.16
Conserved upstream sequences of human class II major histocompatibility genes enhance expression of class II genes in wild-type but not mutant B-cell lines. Proc Natl Acad Sci U S A (1988) 1.12
Differentiation-responsive elements in the 5' region of the mouse tissue plasminogen activator gene confer two-stage regulation by retinoic acid and cyclic AMP in teratocarcinoma cells. Mol Cell Biol (1989) 1.11
Adenovirus 2 peptide IX gene is expressed only on replicated DNA molecules. Mol Cell Biol (1986) 1.10
Evidence for transient requirement of the IgH enhancer. Nucleic Acids Res (1985) 1.10
Herpes simplex virus immediate-early proteins ICP0 and ICP4 activate the endogenous human alpha-globin gene in nonerythroid cells. J Virol (1997) 1.10
A factor binding GATAAG confers tissue specificity on the promoter of the human zeta-globin gene. Nucleic Acids Res (1990) 1.09
Partition of E1A proteins between soluble and structural fractions of adenovirus-infected and -transformed cells. J Virol (1986) 1.09
Regulation of cellular genes transduced by herpes simplex virus. J Virol (1989) 1.07
Adenovirus E1A 12S protein induces DNA synthesis and proliferation in primary epithelial cells in both the presence and absence of serum. J Virol (1987) 1.07
Delimiting regulatory sequences of the Drosophila melanogaster Ddc gene. Mol Cell Biol (1986) 1.06
A fetal globin gene mutation in A gamma nondeletion hereditary persistence of fetal hemoglobin increases promoter strength in a nonerythroid cell. Mol Cell Biol (1988) 1.06
Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat. Mol Cell Biol (1985) 1.04
Tat transactivation of the human immunodeficiency virus type 1 promoter is influenced by basal promoter activity and the simian virus 40 origin of DNA replication. Proc Natl Acad Sci U S A (1991) 1.04
E1a transactivation of human HSP70 gene promoter substitution mutants is independent of the composition of upstream and TATA elements. Mol Cell Biol (1990) 1.03
Role for DNA replication in beta-globin gene activation. Mol Cell Biol (1988) 1.03
IgM receptor-mediated transactivation of the IgH 3' enhancer couples a novel Elf-1-AP-1 protein complex to the developmental control of enhancer function. EMBO J (1995) 1.03
Promoter dependence of enhancer activity. Mol Cell Biol (1984) 1.01
Identification of adenovirus 12-encoded E1A tumor antigens synthesized in infected and transformed mammalian cells and in Escherichia coli. J Virol (1984) 1.01
The SV40 enhancer influences viral late transcription in vitro and in vivo but not on replicating templates. EMBO J (1985) 1.00
Transcription factor IIIA gene expression in Xenopus oocytes utilizes a transcription factor similar to the major late transcription factor. Mol Cell Biol (1989) 1.00
Cellular promoters incorporated into the adenovirus genome: effects of viral regulatory elements on transcription rates and cell specificity of albumin and beta-globin promoters. Mol Cell Biol (1986) 0.99
The adenovirus Ela gene induces differentiation of F9 teratocarcinoma cells. Mol Cell Biol (1987) 0.99
Genetic variation in rates of antipyrine metabolite formation: a study in uninduced twins. Proc Natl Acad Sci U S A (1981) 0.98
Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection. Mol Cell Biol (1985) 0.98
Transcription factor Sp1 is important for retinoic acid-induced expression of the tissue plasminogen activator gene during F9 teratocarcinoma cell differentiation. Mol Cell Biol (1990) 0.95
Cis and trans activation of adenovirus IVa2 gene transcription. Nucleic Acids Res (1985) 0.94
Identification of DNA sequences required for mouse APRT gene expression. Nucleic Acids Res (1988) 0.93
The promoter and enhancer of the inactive chicken beta-globin gene contains precisely positioned nucleosomes. Nucleic Acids Res (1991) 0.90
Expression of transfected vimentin genes in differentiating murine erythroleukemia cells reveals divergent cis-acting regulation of avian and mammalian vimentin sequences. Mol Cell Biol (1987) 0.89
Nuclear protein-binding sites in a transcriptional control region of the rabbit alpha-globin gene. Mol Cell Biol (1993) 0.89
trans activation of type 1 interferon promoters by simian virus 40 T antigen. Mol Cell Biol (1988) 0.89
Autoregulation of adenovirus E1A gene expression. J Virol (1986) 0.89
Regulated expression of human alpha- and beta-globin genes in transient heterokaryons. Mol Cell Biol (1991) 0.89
Activation domains of transcription factors mediate replication dependent transcription from a minimal HIV-1 promoter. Nucleic Acids Res (1996) 0.87
Functional similarities between human immunodeficiency virus type 1 and simian virus 40 kappa B proto-enhancers. J Virol (1991) 0.87
Simian virus 40 revertant enhancers exhibit restricted host ranges for enhancer function. J Virol (1988) 0.87
Subcellular localization of RNAs in transfected cells: role of sequences at the 5' terminus. Nucleic Acids Res (1984) 0.85
Effects of the simian virus 40 origin of replication on transcription from the human immunodeficiency virus type 1 promoter. J Virol (1995) 0.85
Upstream DNA sequences determine different autoregulatory responses of the adenovirus types 5 and 3 E1A promoters. J Virol (1989) 0.85
An immunodominant domain in adenovirus type 2 early region 1A proteins. J Virol (1986) 0.85
Adenovirus type 12 E1A protein expressed in Escherichia coli is functional upon transfer by microinjection or protoplast fusion into mammalian cells. J Virol (1986) 0.85
Synthesis in Escherichia coli of human adenovirus type 12 transforming proteins encoded by early region 1A 13S mRNA and 12S mRNA. Proc Natl Acad Sci U S A (1984) 0.84
Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol (1977) 41.93
Rapid and efficient cosmid cloning. Nucleic Acids Res (1981) 40.13
SV40-transformed simian cells support the replication of early SV40 mutants. Cell (1981) 34.67
In vivo sequence requirements of the SV40 early promotor region. Nature (1981) 25.00
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell (1981) 20.72
A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. Cell (1983) 20.32
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell (1983) 18.86
Immunoglobulin gene transcription is activated by downstream sequence elements. Cell (1983) 15.53
A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene. Cell (1982) 14.32
Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci U S A (1981) 13.67
An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc Natl Acad Sci U S A (1979) 13.21
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
Deletion mapping of DNA regions required for SV40 early region promoter function in vivo. J Mol Appl Genet (1982) 10.71
Enhancer elements. Cell (1983) 10.41
Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system. Cell (1981) 9.81
A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis. Nature (1980) 8.47
A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs. Nucleic Acids Res (1981) 7.57
Transcriptional activation of cloned human beta-globin genes by viral immediate-early gene products. Cell (1983) 7.22
Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product. Cell (1982) 6.78
Specific transcription and RNA splicing defects in five cloned beta-thalassaemia genes. Nature (1983) 6.48
The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements. Cell (1983) 5.67
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proc Natl Acad Sci U S A (1982) 4.69
Purification of genomic sequences from bacteriophage libraries by recombination and selection in vivo. Nucleic Acids Res (1983) 4.32
A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing. Cell (1982) 4.22
Beta + thalassemia: aberrant splicing results from a single point mutation in an intron. Cell (1981) 3.51
Activation of early adenovirus transcription by the herpesvirus immediate early gene: evidence for a common cellular control factor. Proc Natl Acad Sci U S A (1982) 3.29
Differences in human alpha-, beta- and delta-globin gene expression in monkey kidney cells. Cell (1982) 2.78
Correct transcription of a cloned mouse immunoglobulin gene in vivo. Proc Natl Acad Sci U S A (1983) 2.14
Analysis of the transcriptional enhancer effect. Cold Spring Harb Symp Quant Biol (1983) 1.99
Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region. Mol Cell Biol (1982) 1.82
Expression of unselected adenovirus genes in human cells co-transformed with the HSV-1 tk gene and adenovirus 2 DNA. Cell (1980) 1.79
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75
The isolation of structural genes from libraries of eucaryotic DNA. Cell (1978) 37.13
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol (1997) 29.02
Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping. Methods Enzymol (1980) 24.43
Dissecting the regulatory circuitry of a eukaryotic genome. Cell (1998) 23.62
The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA. Cell (1978) 22.88
Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis. Biochemistry (1975) 22.00
The structure and evolution of the human beta-globin gene family. Cell (1980) 21.24
Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell (1979) 21.15
Identification of two distinct regulatory regions adjacent to the human beta-interferon gene. Cell (1983) 17.60
Regulation of inducible and tissue-specific gene expression. Science (1987) 15.04
Amplification and characterization of a beta-globin gene synthesized in vitro. Cell (1976) 14.99
Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell (1984) 12.30
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell (1994) 11.62
The primary structure of rabbit beta-globin mRNA as determined from cloned DNA. Cell (1977) 11.05
Detection and localization of single base changes by denaturing gradient gel electrophoresis. Methods Enzymol (1987) 10.90
Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5' element and c-fos 3' sequences. Cell (1985) 10.00
Pre-mRNA splicing. Annu Rev Genet (1986) 9.86
Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system. Cell (1981) 9.81
Human beta-globin pre-mRNA synthesized in vitro is accurately spliced in Xenopus oocyte nuclei. Cell (1983) 9.77
Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature (1994) 9.37
Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element. Cell (1988) 9.34
Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Cell (1984) 9.13
The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions. Cell (1980) 9.13
Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors. Cell (1986) 9.10
Transcription activation by the adenovirus E1a protein. Nature (1989) 9.08
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature (1990) 8.79
Transcriptional activation: a complex puzzle with few easy pieces. Cell (1994) 8.63
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing. Nature (1987) 8.28
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell (1995) 8.20
The nucleotide sequence of the human beta-globin gene. Cell (1980) 8.11
Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell (1993) 8.07
Molecular cloning and characterization of the human beta-like globin gene cluster. Cell (1980) 7.77
Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev (1989) 7.47
Definition of a novel promoter for the major adenovirus-associated virus mRNA. Cell (1980) 7.42
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell (1993) 7.37
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway. Genes Dev (1995) 7.36
NF-kappa B: a lesson in family values. Cell (1995) 7.33
Transcriptional activation of cloned human beta-globin genes by viral immediate-early gene products. Cell (1983) 7.22
Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell (1995) 7.17
Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell (1992) 7.07
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell (1998) 7.01
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell (1985) 6.85
Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein. Nature (1981) 6.70
Structure of the lambda operators. Nature (1973) 6.66
Cloning and domain structure of the mammalian splicing factor U2AF. Nature (1992) 6.55
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex. Nature (1994) 6.55
Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis. Nucleic Acids Res (1985) 6.52
Specific transcription and RNA splicing defects in five cloned beta-thalassaemia genes. Nature (1983) 6.48
A role for exon sequences and splice-site proximity in splice-site selection. Cell (1986) 6.41
Fine structure genetic analysis of a beta-globin promoter. Science (1986) 6.36
Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3' AU-rich sequences. Nature (1988) 6.35
Detection of single base substitutions by ribonuclease cleavage at mismatches in RNA:DNA duplexes. Science (1985) 6.35
Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter. Cell (2000) 6.32
Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature (1974) 6.22
A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly. Cell (1988) 6.16
Mechanism of action of an acidic transcriptional activator in vitro. Cell (1991) 6.04
Detection of single base substitutions in total genomic DNA. Nature (1985) 5.99
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins. Science (1995) 5.97
The POZ domain: a conserved protein-protein interaction motif. Genes Dev (1994) 5.96
Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature (1994) 5.95
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell (1996) 5.91
The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta gene. Cell (1992) 5.85
The human beta-interferon gene enhancer is under negative control. Cell (1986) 5.61
Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J (1995) 5.59
The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell (1989) 5.50
Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell (1995) 5.44
A sensitive method for the determination of protein-DNA binding specificities. Nucleic Acids Res (1990) 5.42
Chemotherapy of advanced Hodgkin's disease with MOPP, ABVD, or MOPP alternating with ABVD. N Engl J Med (1992) 5.42
Sequence-specific RNA binding by the HIV-1 Rev protein. Nature (1989) 5.36
Enzymatic in vitro synthesis of globin genes. Cell (1976) 5.31
Intron sequences involved in lariat formation during pre-mRNA splicing. Cell (1985) 5.30
Multiple repressor binding at the operators in bacteriophage lambda. Proc Natl Acad Sci U S A (1973) 5.15
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Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc Natl Acad Sci U S A (1989) 5.11
A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA. Cell (1993) 4.82
Binding of general transcription factor TFIIB to an acidic activating region. Nature (1991) 4.71
NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev (2001) 4.70
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proc Natl Acad Sci U S A (1982) 4.69
Human beta-interferon gene expression is regulated by an inducible enhancer element. Cell (1985) 4.68
A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein. Cell (1990) 4.67
The molecular genetics of human hemoglobins. Annu Rev Genet (1980) 4.67
A randomized trial of induction chemotherapy plus high-dose radiation versus radiation alone in stage III non-small-cell lung cancer. N Engl J Med (1990) 4.66
Structure and in vitro transcription of human globin genes. Science (1980) 4.65
Human SRF-related proteins: DNA-binding properties and potential regulatory targets. Genes Dev (1991) 4.63
A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature (1990) 4.57
An adenovirus E1a protein region required for transformation and transcriptional repression. Cell (1986) 4.56
An ordered pathway of snRNP binding during mammalian pre-mRNA splicing complex assembly. EMBO J (1987) 4.52
Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. Cell (1999) 4.52
Dose and dose intensity as determinants of outcome in the adjuvant treatment of breast cancer. The Cancer and Leukemia Group B. J Natl Cancer Inst (1998) 4.43