Published in EMBO J on June 01, 1986
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Breakpoints of gross deletions coincide with non-B DNA conformations. Proc Natl Acad Sci U S A (2004) 2.13
A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats. Nucleic Acids Res (1992) 2.03
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Instability of long inverted repeats within mouse transgenes. EMBO J (1996) 1.67
Short, direct repeats at the breakpoints of deletions of the retinoblastoma gene. Proc Natl Acad Sci U S A (1989) 1.61
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High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genome. Mol Cell Biol (1996) 1.50
DNA sequence analysis of spontaneous mutations in the SUP4-o gene of Saccharomyces cerevisiae. Mol Cell Biol (1988) 1.50
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Isolation and characterization of Escherichia coli mutants with altered rates of deletion formation. Genetics (1991) 1.48
A hotspot for novel amplification joints in a mosaic of Alu-like repeats and palindromic A + T-rich DNA. EMBO J (1987) 1.47
Retracted Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences. EMBO J (1989) 1.44
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Instability of a plasmid-borne inverted repeat in Saccharomyces cerevisiae. Genetics (1993) 1.35
Extreme structural heterogeneity among the members of a maize retrotransposon family. Genetics (1998) 1.29
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Formation of large deletions by illegitimate recombination in the HPRT gene of primary human fibroblasts. Proc Natl Acad Sci U S A (1993) 1.27
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Molecular analysis of two mouse dilute locus deletion mutations: spontaneous dilute lethal20J and radiation-induced dilute prenatal lethal Aa2 alleles. Mol Cell Biol (1990) 1.16
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An unusual pattern of spontaneous mutations recovered in the halophilic archaeon Haloferax volcanii. Genetics (2006) 1.07
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Molecular analysis of DNA junctions produced by illegitimate recombination in human cells. Nucleic Acids Res (1992) 0.95
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High frequency of large spontaneous deletions of DNA in tumor-derived CHEF cells. Proc Natl Acad Sci U S A (1989) 0.85
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Recombination resulting in unusual features in the polyomavirus genome isolated from a murine tumor cell line. J Virol (1990) 0.75
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Screening lambdagt recombinant clones by hybridization to single plaques in situ. Science (1977) 83.82
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Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis. Gene (1983) 44.52
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On the formation of spontaneous deletions: the importance of short sequence homologies in the generation of large deletions. Cell (1982) 9.72
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High mutation frequency in DNA transfected into mammalian cells. Proc Natl Acad Sci U S A (1983) 6.05
The molecular genetics of human hemoglobin. Prog Nucleic Acid Res Mol Biol (1984) 5.50
Structural organization of the bcr gene and its role in the Ph' translocation. Nature (1985) 4.08
Unexpected relationships between four large deletions in the human beta-globin gene cluster. Cell (1983) 3.57
T4 endonuclease VII cleaves holliday structures. Cell (1982) 3.47
Structural intermediates of deletion mutagenesis: a role for palindromic DNA. Proc Natl Acad Sci U S A (1984) 3.17
Isolation of transforming DNA: cloning the hamster aprt gene. Cell (1980) 2.73
Translocation of the myc cellular oncogene to the immunoglobulin heavy chain locus in murine plasmacytomas is an imprecise reciprocal exchange. Cell (1984) 2.60
The Chinese hamster Alu-equivalent sequence: a conserved highly repetitious, interspersed deoxyribonucleic acid sequence in mammals has a structure suggestive of a transposable element. Mol Cell Biol (1981) 2.56
Genetic and physical mapping in the early region of bacteriophage T7 DNA. J Mol Biol (1979) 2.52
Cruciform-resolvase interactions in supercoiled DNA. Cell (1984) 2.43
Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA. Nucleic Acids Res (1984) 2.37
Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination. Science (1985) 2.26
Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement. Proc Natl Acad Sci U S A (1985) 2.17
DNA sequence studies of simian virus 40 chromosomal excision and integration in rat cells. J Mol Biol (1984) 1.88
A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin. Nature (1982) 1.77
Cleavage of cruciform DNA structures by an activity from Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1985) 1.64
The deletion in a type of delta 0-beta 0-thalassaemia begins in an inverted AluI repeat. Nature (1982) 1.56
High-frequency nonrandom mutational event at the adenine phosphoribosyltransferase (aprt) locus of sib-selected CHO variants heterozygous for aprt. Somatic Cell Genet (1982) 1.48
Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells. J Mol Biol (1983) 1.45
Detection of deletion mutations in pSV2gpt-transformed cells. Mol Cell Biol (1984) 1.42
A Chinese G gamma + (A gamma delta beta)zero thalassemia deletion: comparison to other deletions in the human beta-globin gene cluster and sequence analysis of the breakpoints. Nucleic Acids Res (1985) 1.42
Nucleotide sequence of hamster adenine phosphoribosyl transferase (aprt) gene. Nucleic Acids Res (1986) 1.37
Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferase. Cell (1974) 1.36
Duplication followed by deletion accounts for the structure of an Indian deletion beta (0)-thalassemia gene. Nucleic Acids Res (1982) 1.31
Analysis of an inversion within the human beta globin gene cluster. Nucleic Acids Res (1985) 1.18
Large scale isolation of nuclei and nucleoli from vitellogenic oocytes of Xenopus laevis. Chromosoma (1978) 1.09
Statistical significance of partial base-pairing potential: implications for recombination of SV40 DNA in eukaryotic cells. Nucleic Acids Res (1983) 0.90
An established pre-adipose cell line and its differentiation in culture. Cell (1974) 5.97
Genetic mapping of the human X chromosome by using restriction fragment length polymorphisms. Proc Natl Acad Sci U S A (1984) 4.22
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. Cell (1998) 4.00
Mutator phenotypes in human colorectal carcinoma cell lines. Proc Natl Acad Sci U S A (1994) 3.10
Mapping replication units in animal cells. Cell (1989) 2.99
New class of selective stimulants of beta-adrenergic receptors. Nature (1968) 2.72
Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline. Neuron (1993) 2.65
glial cells missing: a genetic switch that controls glial versus neuronal fate. Cell (1995) 2.25
Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci (2000) 2.22
Sucl+ encodes a predicted 13-kilodalton protein that is essential for cell viability and is directly involved in the division cycle of Schizosaccharomyces pombe. Mol Cell Biol (1987) 2.13
Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell (1990) 2.06
Conditional mutator phenotypes in hMSH2-deficient tumor cell lines. Science (1997) 2.04
Validation of self-reported hearing loss. The Blue Mountains Hearing Study. Int J Epidemiol (2001) 2.00
Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J Cell Biol (1996) 1.92
Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease. Proc Natl Acad Sci U S A (1995) 1.91
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Apoptosis induced by overexpression of hMSH2 or hMLH1. Cancer Res (1999) 1.58
Use of community-based mental health programs by HMOs: evidence from a Medicaid demonstration. Am J Public Health (1992) 1.57
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Effect of time-limited psychotherapy on patient dropout rates. Am J Psychiatry (1990) 1.49
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Structure of mutant alleles at the aprt locus of Chinese hamster ovary cells. J Mol Biol (1983) 1.45
Structural and functional analysis of the human thymidylate synthase gene. J Biol Chem (1990) 1.43
Characterization of a mutator gene in Chinese hamster ovary cells. Proc Natl Acad Sci U S A (1979) 1.43
Hyperproduction and purification of nicotinamide deamidase, a microconstitutive enzyme of Escherichia coli. J Biol Chem (1971) 1.41
Family planning: personal and political perspectives from Choiseul Province, Solomon Islands. Aust J Public Health (1995) 1.38
Nucleotide sequence of hamster adenine phosphoribosyl transferase (aprt) gene. Nucleic Acids Res (1986) 1.37
Response of colon cancer cell lines to the introduction of APC, a colon-specific tumor suppressor gene. Cancer Res (1995) 1.37
DNA amplification--deletion in a spontaneous mutation of the hamster aprt locus: structure and sequence of the novel joint. Nucleic Acids Res (1986) 1.35
A clinically useful DNA probe closely linked to haemophilia A. Lancet (1984) 1.33
Molecular analysis of mutations in mutator colorectal carcinoma cell lines. Hum Mol Genet (1995) 1.32
Mutator phenotype in Msh2-deficient murine embryonic fibroblasts. Cancer Res (1997) 1.31
Generation of high-titer defective HSV-1 vectors using an IE 2 deletion mutant and quantitative study of expression in cultured cortical cells. Biotechniques (1996) 1.28
Next-nucleotide effects in mutations driven by DNA precursor pool imbalances at the aprt locus of Chinese hamster ovary cells. Proc Natl Acad Sci U S A (1987) 1.28
A new species of Phoma causes ascochyta blight symptoms on field peas (Pisum sativum) in South Australia. Mycologia (2009) 1.27
p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res (1994) 1.27
DNA sequence analysis of spontaneous mutations at the aprt locus of hamster cells. Mol Cell Biol (1987) 1.26
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Deoxyribonucleotide pools in mouse-fibroblast cell lines with altered ribonucleotide reductase. Eur J Biochem (1976) 1.21
Prevalence and correlates of cutting behavior: risk for HIV transmission. J Am Acad Child Adolesc Psychiatry (1991) 1.20
Availability of rural Minnesota obstetric services: is it a problem? J Rural Health (1995) 1.19
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Molecular basis of spontaneous mutation at the aprt locus of hamster cells. J Mol Biol (1989) 1.14
Alterations leading to increased ribonucleotide reductase in cells selected for resistance to deoxynucleosides. Cell (1974) 1.14
Alterations of gene structure in ethyl methane sulfonate-induced mutants of mammalian cells. Mol Cell Biol (1982) 1.12
Dax, a locust Hox gene related to fushi-tarazu but showing no pair-rule expression. Development (1994) 1.11
The influence of a (GT)29 microsatellite sequence on homologous recombination in the hamster adenine phosphoribosyltransferase gene. Nucleic Acids Res (1996) 1.11
Structure and sequence of mutations induced by ionizing radiation at selectable loci in Chinese hamster ovary cells. J Mol Biol (1986) 1.08
Search for stopped Gluinos in pp collisions at square root s=7 TeV. Phys Rev Lett (2011) 1.07
Modulation of Starling forces and muscle fiber maturity permits adenovirus-mediated gene transfer to adult dystrophic (mdx) mice by the intravascular route. Hum Gene Ther (2000) 1.06
Chromosome mapping of the human cytidine-5'-triphosphate synthetase (CTPS) gene to band 1p34.1-p34.3 by fluorescence in situ hybridization. Hum Genet (1991) 1.05
An update of the Zenith endovascular graft for abdominal aortic aneurysms: initial implantation and mid-term follow-up data. J Vasc Surg (2001) 1.05
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Proteomic analysis of voided urine after prostatic massage from patients with prostate cancer: a pilot study. Urology (2004) 1.03
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Measurement of the polarization of W bosons with large transverse momenta in W + jets events at the LHC. Phys Rev Lett (2011) 0.99
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Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles. Hum Gene Ther (1999) 0.99
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High rate of multilocus deletion in a human tumor cell line. Hum Mol Genet (1993) 0.98
Measurement of the inclusive jet cross section in pp collisions at √s = 7 TeV. Phys Rev Lett (2011) 0.98
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Search for neutral minimal supersymmetric standard model Higgs bosons decaying to tau pairs in pp collisions at √s=7 TeV. Phys Rev Lett (2011) 0.97
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Genetic instability and transitional cell carcinoma of the bladder. BJU Int (2004) 0.95
Hybrid open-endoluminal technique for repair of thoracoabdominal aneurysm involving the celiac axis. J Endovasc Ther (2000) 0.94
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A methotrexate insensitive variant of folate reductase present in two lines of methotrexate-resistant L5178Y cells. Eur J Cancer (1980) 0.92
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