PubRank

B J Mayer

Author PubWeight™ 83.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of a ten-amino acid proline-rich SH3 binding site. Science 1993 8.05
2 Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 1995 6.20
3 Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. Science 1992 4.57
4 Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature 1992 4.46
5 Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell 2000 4.21
6 Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science 1990 3.67
7 A putative modular domain present in diverse signaling proteins. Cell 1993 2.90
8 Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway. J Biol Chem 2001 2.85
9 Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins. Mol Cell Biol 1995 2.44
10 Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck. Curr Biol 1997 2.24
11 Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability. Curr Biol 2000 2.19
12 NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling. Proc Natl Acad Sci U S A 1999 2.03
13 The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity. Nature 1998 2.01
14 The product of the cellular crk gene consists primarily of SH2 and SH3 regions. Cell Growth Differ 1992 1.94
15 Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins. Mol Cell Biol 1991 1.92
16 Tyrosine-phosphorylated epidermal growth factor receptor and cellular p130 provide high affinity binding substrates to analyze Crk-phosphotyrosine-dependent interactions in vitro. J Biol Chem 1992 1.75
17 Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J 2001 1.74
18 Genetic lesions involved in temperature sensitivity of the src gene products of four Rous sarcoma virus mutants. J Virol 1986 1.64
19 Three-dimensional solution structure of the src homology 2 domain of c-abl. Cell 1992 1.53
20 SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase. Virology 1998 1.49
21 p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases. Mol Cell Biol 1997 1.46
22 The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck. J Biol Chem 1998 1.39
23 Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters. J Virol 1986 1.38
24 Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B. Proc Natl Acad Sci U S A 2006 1.27
25 Two independent mutations are required for temperature-sensitive cell transformation by a Rous sarcoma virus temperature-sensitive mutant. J Virol 1985 1.25
26 Mechanism of activation of Pak1 kinase by membrane localization. Oncogene 1999 1.22
27 Crk is required for apoptosis in Xenopus egg extracts. EMBO J 1997 1.13
28 Phosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesis. J Biol Chem 2000 1.08
29 Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding. Proc Natl Acad Sci U S A 2001 1.06
30 The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct. Structure 1995 1.04
31 Induction of tumors and generation of recovered sarcoma viruses by, and mapping of deletions in, two molecularly cloned src deletion mutants. J Virol 1984 1.04
32 Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck. J Biol Chem 1999 1.02
33 Dominant-negative mutants of the SH2/SH3 adapters Nck and Grb2 inhibit MAP kinase activation and mesoderm-specific gene induction by eFGF in Xenopus. Oncogene 1998 0.99
34 A novel oncogene, v-ryk, encoding a truncated receptor tyrosine kinase is transduced into the RPL30 virus without loss of viral sequences. J Virol 1992 0.96
35 Expression of mutated Nck SH2/SH3 adaptor respecifies mesodermal cell fate in Xenopus laevis development. Proc Natl Acad Sci U S A 1997 0.94
36 Direct analysis of the binding of the abl Src homology 2 domain to the activated epidermal growth factor receptor. J Biol Chem 1993 0.90
37 c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase. Mol Cell Biol 2000 0.90
38 Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor. Oncogene 2001 0.88
39 Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformation. Oncogene 2010 0.84
40 Analysis of p60v-src mutants carrying lesions involved in temperature sensitivity. J Virol 1987 0.83
41 Concentration-dependent positive and negative regulation of a MAP kinase by a MAP kinase kinase. Oncogene 1999 0.82
42 Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development. J Biol Chem 2000 0.78
43 Engineering temperature-sensitive SH3 domains. Chem Biol 1999 0.76
44 Cell transformation by an oncogene that regulates protein kinases. Adv Second Messenger Phosphoprotein Res 1990 0.75
45 Growth inhibition by Abl requires an interplay of its SH2 and tyrosine kinase domains. FEBS Lett 1996 0.75