Published in EMBO J on July 02, 2001
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Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion. Mol Cell Biol (2002) 1.02
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Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein. Mol Biol Cell (2010) 0.88
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Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities. J Biol Chem (2011) 0.85
C3G regulates the size of the cerebral cortex neural precursor population. EMBO J (2006) 0.85
RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. Blood (2010) 0.84
Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability. Immunol Cell Biol (2016) 0.84
Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia. Haematologica (2014) 0.82
Rap1 can bypass the FAK-Src-Paxillin cascade to induce cell spreading and focal adhesion formation. PLoS One (2012) 0.82
Cdk5 regulates Rap1 activity. Neurochem Int (2013) 0.81
Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study. PLoS One (2011) 0.80
Discontinuities in Rap1 activity determine epithelial cell morphology within the developing wing of Drosophila. Dev Biol (2012) 0.80
C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion. Cell Commun Signal (2013) 0.78
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Ras-proximate-1 GTPase-activating protein and Rac2 may play pivotal roles in the initial development of myelodysplastic syndrome. Oncol Lett (2012) 0.77
TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells. PLoS One (2011) 0.77
Roles of Rap1 signaling in tumor cell migration and invasion. Cancer Biol Med (2017) 0.75
C3G shows regulated nucleocytoplasmic exchange and represses histone modifications associated with euchromatin. Mol Biol Cell (2017) 0.75
C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms. Oncotarget (2016) 0.75
The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster. PLoS One (2010) 0.75
p53 target gene Rap2B regulates the cytoskeleton and inhibits cell spreading. J Cancer Res Clin Oncol (2015) 0.75
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