Published in Proc Natl Acad Sci U S A on December 01, 1986
Isolation and characterization of the human Gs alpha gene. Proc Natl Acad Sci U S A (1988) 2.55
Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions. Proc Natl Acad Sci U S A (1988) 2.54
Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies. Proc Natl Acad Sci U S A (1989) 2.31
Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment. Proc Natl Acad Sci U S A (1990) 1.87
Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins. Biochem J (1988) 1.86
Heterotrimeric G-proteins: a short history. Br J Pharmacol (2006) 1.79
Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies. Neurosignals (2008) 1.73
Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go. Proc Natl Acad Sci U S A (1990) 1.42
Genetic deficiency of the alpha subunit of the guanine nucleotide-binding protein Gs as the molecular basis for Albright hereditary osteodystrophy. Proc Natl Acad Sci U S A (1988) 1.40
A small multigene family encodes Gi signal-transduction proteins. Proc Natl Acad Sci U S A (1987) 1.39
Persistent activation of the alpha subunit of Gs promotes its removal from the plasma membrane. Biochem J (1989) 1.31
Human cDNA clones for an alpha subunit of Gi signal-transduction protein. Proc Natl Acad Sci U S A (1987) 1.28
Decreased stimulatory guanosine triphosphate binding protein in dogs with pressure-overload left ventricular failure. J Clin Invest (1988) 1.26
Primary and secondary structure of bovine retinal S antigen (48-kDa protein). Proc Natl Acad Sci U S A (1987) 1.25
A second form of the beta subunit of signal-transducing G proteins. Proc Natl Acad Sci U S A (1987) 1.21
Differential expression of novel Gs alpha signal transduction protein cDNA species. Nucleic Acids Res (1991) 1.18
Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins. Proc Natl Acad Sci U S A (1987) 1.17
Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology. Pharmacol Ther (2007) 1.15
Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines. Proc Natl Acad Sci U S A (1988) 1.13
Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing. Proc Natl Acad Sci U S A (1991) 1.13
Two forms of Drosophila melanogaster Gs alpha are produced by alternate splicing involving an unusual splice site. Mol Cell Biol (1990) 1.06
XLalphas, the extra-long form of the alpha-subunit of the Gs G protein, is significantly longer than suspected, and so is its companion Alex. Proc Natl Acad Sci U S A (2004) 1.06
The Drosophila gene coding for the alpha subunit of a stimulatory G protein is preferentially expressed in the nervous system. Proc Natl Acad Sci U S A (1989) 1.05
Genetic identification of residues involved in association of alpha and beta G-protein subunits. Mol Cell Biol (1994) 1.02
The role of GNAS and other imprinted genes in the development of obesity. Int J Obes (Lond) (2009) 1.00
Cholera toxin treatment produces down-regulation of the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs). Biochem J (1989) 1.00
The GNAS Locus: Quintessential Complex Gene Encoding Gsalpha, XLalphas, and other Imprinted Transcripts. Curr Genomics (2007) 0.97
Guanine-nucleotide-binding proteins Gi and Gs in fat-cells from normal, hypothyroid and obese human subjects. Biochem J (1989) 0.97
Decreased bioactivity of the guanine nucleotide-binding protein that stimulates adenylate cyclase in hearts from cardiomyopathic Syrian hamsters. J Clin Invest (1989) 0.95
Isolation of the serotoninergic 5-HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cell lines. Br J Pharmacol (2000) 0.89
Reduced expression of multiple forms of the alpha subunit of the stimulatory GTP-binding protein in pseudohypoparathyroidism type Ia. Proc Natl Acad Sci U S A (1987) 0.89
Impaired cardiac muscarinic receptor function in dogs with heart failure. J Clin Invest (1988) 0.88
Phosphorylation of the spliced variant forms of the recombinant stimulatory guanine-nucleotide-binding regulatory protein (Gs alpha) by protein kinase C. Biochem J (1992) 0.88
Amino- and carboxy-terminal deletion mutants of Gs alpha are localized to the particulate fraction of transfected COS cells. J Cell Biol (1992) 0.87
Cholera toxin inhibits signal transduction by several mitogens and the in vitro growth of human small-cell lung cancer. J Clin Invest (1990) 0.87
Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells. Proc Natl Acad Sci U S A (1991) 0.87
Insulin activates GTP binding to a 40 kDa protein in fat cells. Biochem J (1991) 0.86
Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line. Biochem J (1988) 0.86
Different forms of Go alpha mRNA arise by alternative splicing of transcripts from a single gene on human chromosome 16. Mol Cell Biol (1991) 0.84
Maintenance of cellular levels of G-proteins: different efficiencies of alpha s and alpha o synthesis in GH3 cells. Biochem J (1996) 0.83
Coupling of beta2-adrenoceptors to XLalphas and Galphas: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther (2009) 0.83
Identification of a novel mutation in a pseudohypoparathyroidism family. Int J Endocrinol (2011) 0.81
Characterization of GTP-binding proteins in Golgi-associated membrane vesicles from rat adipocytes. Biochem J (1992) 0.80
Coordinate down-regulation of adenylyl cyclase isoforms and the stimulatory G protein (G(s)) in intestinal epithelial cell differentiation. J Biol Chem (2010) 0.79
The cDNA sequence of the alpha-subunit of the Chinese hamster adenylate cyclase-stimulatory G-protein. Nucleic Acids Res (1990) 0.78
Defective ANF-R2/ANP-C receptor-mediated signalling in hypertension. Mol Cell Biochem (1996) 0.77
Modulation of Gi Proteins in Hypertension: Role of Angiotensin II and Oxidative Stress. Curr Cardiol Rev (2010) 0.76
Desensitization to parathyroid hormone in renal cells from aged rats is associated with alterations in G-protein activity. J Clin Invest (1989) 0.76
Aberrant splicing of Gs alpha transcript in transformed human astroglial and glioblastoma cell lines. Nucleic Acids Res (1992) 0.75
Nitric oxide attenuates overexpression of Giα proteins in vascular smooth muscle cells from SHR: Role of ROS and ROS-mediated signaling. PLoS One (2017) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Empirical predictions of protein conformation. Annu Rev Biochem (1978) 25.48
Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41
G proteins and dual control of adenylate cyclase. Cell (1984) 11.05
GTP-binding proteins couple cardiac muscarinic receptors to a K channel. Nature (1985) 4.95
Homologies between signal transducing G proteins and ras gene products. Science (1984) 3.85
Primary structure of the alpha-subunit of transducin and its relationship to ras proteins. Nature (1985) 3.28
Regulation of HIS4-lacZ fusions in Saccharomyces cerevisiae. Mol Cell Biol (1982) 3.07
Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. Proc Natl Acad Sci U S A (1986) 2.83
Structure and expression in L-cells of a cloned H4 histone gene of the mouse. J Mol Biol (1981) 2.76
The regulatory component of adenylate cyclase. Purification and properties. J Biol Chem (1981) 2.69
Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3':5'-monophosphate-dependent protein kinase. J Biol Chem (1985) 2.55
Sequence of the alpha subunit of photoreceptor G protein: homologies between transducin, ras, and elongation factors. Science (1985) 2.46
Molecular basis for two forms of the G protein that stimulates adenylate cyclase. J Biol Chem (1986) 2.35
Molecular cloning of complementary DNA for the alpha subunit of the G protein that stimulates adenylate cyclase. Science (1985) 2.35
Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence. Proc Natl Acad Sci U S A (1985) 2.34
Identification of specific transducin alpha subunits in retinal rod and cone photoreceptors. Science (1986) 1.96
Action of single-strand specific nucleases on model DNA heteroduplexes of defined size and sequence. Biochemistry (1977) 1.94
Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase. Proc Natl Acad Sci U S A (1986) 1.86
Primary structure of the alpha-subunit of bovine adenylate cyclase-inhibiting G-protein deduced from the cDNA sequence. FEBS Lett (1986) 1.57
Analysis of 5' flanking sequences and intron-exon boundaries of the rat prolactin gene. J Biol Chem (1981) 1.38
Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils. J Biol Chem (1986) 1.33
Guanine nucleotide-sensitive, high affinity binding of carbachol to muscarinic cholinergic receptors of 1321N1 astrocytoma cells is insensitive to pertussis toxin. Mol Pharmacol (1985) 1.24
Primary structure of the alpha-subunit of bovine adenylate cyclase-stimulating G-protein deduced from the cDNA sequence. FEBS Lett (1986) 1.16
In vitro mutagenesis of the promoter region for a vaccinia virus gene: evidence for tandem early and late regulatory signals. J Virol (1985) 5.77
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature (1997) 5.35
Neurotransmitter synthesis by neuroblastoma clones (neuroblast differentiation-cell culture-choline acetyltransferase-acetylcholinesterase-tyrosine hydroxylase-axons-dendrites). Proc Natl Acad Sci U S A (1972) 5.30
RNA codewords and protein synthesis, VII. On the general nature of the RNA code. Proc Natl Acad Sci U S A (1965) 5.17
Release factors differing in specificity for terminator codons. Proc Natl Acad Sci U S A (1968) 4.18
Monoclonal antibody to a plasma membrane antigen of neurons. Proc Natl Acad Sci U S A (1979) 4.09
Morphine receptors as regulators of adenylate cyclase activity. Proc Natl Acad Sci U S A (1975) 3.10
Regulation of acetylcholinesterase in neuroblastoma cells. Proc Natl Acad Sci U S A (1970) 2.89
RNA codewords and protein synthesis, 8. Nucleotide sequences of synonym codons for arginine, valine, cysteine, and alanine. Proc Natl Acad Sci U S A (1965) 2.86
Neuronal tumor cells with excitable membranes grown in vitro. Proc Natl Acad Sci U S A (1969) 2.75
A neuroblastoma times glioma hybrid cell line with morphine receptors. Proc Natl Acad Sci U S A (1974) 2.72
Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance. Proc Natl Acad Sci U S A (1975) 2.71
Selective transcription of vaccinia virus genes in template dependent soluble extracts of infected cells. Cell (1983) 2.62
Alternative splicing accounts for the four forms of myelin basic protein. Cell (1985) 2.61
Genes for neuronal properties expressed in neuroblastoma x L cell hybrids. Proc Natl Acad Sci U S A (1971) 2.35
Transfer RNA as a cofactor coupling amino acid synthesis with that of protein. Proc Natl Acad Sci U S A (1968) 2.31
A guide to the effective use of otoacoustic emissions. Ear Hear (1990) 2.31
Genetic dissection of neural properties using somatic cell hybrids. Nat New Biol (1972) 2.27
Increased susceptibility to malaria during the early postpartum period. N Engl J Med (2000) 2.24
Sequential translation of trinucleotide codons for the initiation and termination of protein synthesis. Science (1968) 2.20
Neurological dysfunction and axonal degeneration in Charcot-Marie-Tooth disease type 1A. Brain (2000) 2.10
Synapse formation between clonal neuroblastoma X glioma hybrid cells and striated muscle cells. Proc Natl Acad Sci U S A (1976) 2.06
Drosophila NK-homeobox genes. Proc Natl Acad Sci U S A (1989) 2.04
Variation of Plasmodium falciparum msp1 block 2 and msp2 allele prevalence and of infection complexity in two neighbouring Senegalese villages with different transmission conditions. Trans R Soc Trop Med Hyg (1999) 2.02
RNA codons and protein synthesis. 15. Dissimilar responses of mammalian and bacterial transfer RNA fractions to messenger RNA codons. J Mol Biol (1968) 2.00
Use of specific antibodies to quantitate the guanine nucleotide-binding protein Go in brain. Proc Natl Acad Sci U S A (1986) 2.00
Fine structure of RNA codewords recognized by bacterial, amphibian, and mammalian transfer RNA. Science (1967) 1.99
The RNA code and protein synthesis. Cold Spring Harb Symp Quant Biol (1966) 1.96
Epidemiological and virological influenza survey in Dakar, Senegal: 1996-1998. Am J Trop Med Hyg (2000) 1.96
Normal chest radiography in pulmonary tuberculosis: implications for obtaining respiratory specimen cultures. Int J Tuberc Lung Dis (2008) 1.94
Clinical features in affected individuals from 21 pedigrees with dominant optic atrophy. Arch Ophthalmol (1998) 1.93
Double-stranded RNA unwinding and modifying activity is detected ubiquitously in primary tissues and cell lines. Mol Cell Biol (1990) 1.89
Nucleotide sequence analysis of the purEK operon encoding 5'-phosphoribosyl-5-aminoimidazole carboxylase of Escherichia coli K-12. J Bacteriol (1989) 1.88
Plasmodium falciparum clinical malaria: lessons from longitudinal studies in Senegal. Parassitologia (1999) 1.86
Hereditary hemochromatosis. Diagnosis in siblings and children. N Engl J Med (1977) 1.85
Regulation of adenylate cyclase of neuroblastoma x glioma hybrid cells by alpha-adrenergic receptors. I. Inhibition of adenylate cyclase mediated by alpha receptors. J Biol Chem (1979) 1.82
Impact of the new EU health warnings on the Dutch quit line. Tob Control (2002) 1.79
A topographic gradient of molecules in retina can be used to identify neuron position. Proc Natl Acad Sci U S A (1981) 1.77
Regulatory mechanisms and protein synthesis. X. Codon recognition on 30 S ribosomes. J Mol Biol (1966) 1.76
Sodium uptake associated with activation of action potential ionophores of cultured neuroblastoma and muscle cells. Proc Natl Acad Sci U S A (1973) 1.74
Ritual, habit, and perfectionism: the prevalence and development of compulsive-like behavior in normal young children. Child Dev (1997) 1.71
Effect of catecholamines on the adenosine 3':5'-cyclic monophosphate concentrations of clonal satellite cells of neurons. Proc Natl Acad Sci U S A (1971) 1.65
Identification of three forms of human myelin basic protein by cDNA cloning. Proc Natl Acad Sci U S A (1986) 1.64
Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice. Blood (2001) 1.62
Opiate-dependent modulation of adenylate cyclase. Proc Natl Acad Sci U S A (1977) 1.60
Skin biopsies demonstrate MPZ splicing abnormalities in Charcot-Marie-Tooth neuropathy 1B. Neurology (2006) 1.59
White matter changes associated with deletions of the long arm of chromosome 18 (18q- syndrome): a dysmyelinating disorder? AJNR Am J Neuroradiol (1997) 1.58
Modulation of synapse formation by cyclic adenosine monophosphate. Science (1983) 1.56
Myelin deficient mice: expression of myelin basic protein and generation of mice with varying levels of myelin. Cell (1987) 1.55
Antisera against a guanine nucleotide binding protein from retina cross-react with the beta subunit of the adenylyl cyclase-associated guanine nucleotide binding proteins, Ns and Ni. Proc Natl Acad Sci U S A (1985) 1.54
Monocyte chemotactic factor produced by large vessel endothelial cells in vitro. Arteriosclerosis (1986) 1.54
Acoustic emission cochleography--practical aspects. Scand Audiol Suppl (1986) 1.52
In-vitro activity of pyronaridine and amodiaquine against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial agents. J Antimicrob Chemother (1998) 1.51
Morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis of the knee. Osteoarthritis Cartilage (2011) 1.47
Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases. Proc Natl Acad Sci U S A (1981) 1.47
Adverse events temporally associated with immunizing agents--1989 report. Can Dis Wkly Rep (1991) 1.45
DM-GRASP, a novel immunoglobulin superfamily axonal surface protein that supports neurite extension. Neuron (1991) 1.45
Structure and evolution of four POU domain genes expressed in mouse brain. Proc Natl Acad Sci U S A (1992) 1.43
Axons regulate Schwann cell expression of the POU transcription factor SCIP. J Neurosci (1994) 1.42
DNA-dependent RNA polymerase subunits encoded within the vaccinia virus genome. J Virol (1987) 1.42
Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation. J Biol Chem (1994) 1.41
Molecular analysis of the 18q- syndrome--and correlation with phenotype. Am J Hum Genet (1993) 1.40
Receptor-mediated shifts in cGMP and cAMP levels in neuroblastoma cells. Proc Natl Acad Sci U S A (1975) 1.40
Citrus juice treated with exchange resins. N Engl J Med (1973) 1.39
Transgenic plants as factories for biopharmaceuticals. Nat Biotechnol (2000) 1.39
Localization of acetylcholine receptors during synaptogenesis in retina. Proc Natl Acad Sci U S A (1976) 1.38
An advanced cochlear echo technique suitable for infant screening. Br J Audiol (1987) 1.37
On the specificity of synapse formation. Proc Natl Acad Sci U S A (1976) 1.36
Antibiotics for prophylaxis of Plasmodium falciparum infections: in vitro activity of doxycycline against Senegalese isolates. Am J Trop Med Hyg (2000) 1.35
In vitro activities of benflumetol against 158 Senegalese isolates of Plasmodium falciparum in comparison with those of standard antimalarial drugs. Antimicrob Agents Chemother (1999) 1.35
Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells. Proc Natl Acad Sci U S A (1986) 1.35
Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry (1997) 1.34
The physiopathological significance of benign monoclonal gammopathy: a study of 64 cases. Br J Haematol (1980) 1.34
What's happening with consumer participation? Aust N Z J Ment Health Nurs (1996) 1.34
Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils. J Biol Chem (1986) 1.33
Adverse events temporally associated with immunizing agents--1987 report. Can Dis Wkly Rep (1989) 1.33
Identification of the GTP-binding protein encoded by Gi3 complementary DNA. J Biol Chem (1988) 1.33
Mutation of the proteolipid protein gene PLP in a human X chromosome-linked myelin disorder. Proc Natl Acad Sci U S A (1989) 1.32
Synapse turnover: the formation and termination of transient synapses. Proc Natl Acad Sci U S A (1977) 1.31
GTP-binding proteins in brain and neutrophil are tethered to the plasma membrane via their amino termini. Biochem Biophys Res Commun (1987) 1.30
Antibodies against the carboxyl-terminal 5-kDa peptide of the alpha subunit of transducin crossreact with the 40-kDa but not the 39-kDa guanine nucleotide binding protein from brain. Proc Natl Acad Sci U S A (1985) 1.30
Synapse formation between two clonal cell lines. Science (1977) 1.30
Human cDNA clones for an alpha subunit of Gi signal-transduction protein. Proc Natl Acad Sci U S A (1987) 1.28
Similar feeding preferences of Anopheles gambiae and A. arabiensis in Senegal. Trans R Soc Trop Med Hyg (1998) 1.28
Measurement of exhaled chlorofluorocarbons. Lancet (1988) 1.27
Synapse and acetylcholine receptor synthesis by neurons dissociated from retina. Proc Natl Acad Sci U S A (1976) 1.26
A cohort study of Plasmodium falciparum diversity during the dry season in Ndiop, a Senegalese village with seasonal, mesoendemic malaria. Trans R Soc Trop Med Hyg (2000) 1.26
Immunological and molecular characterization of Go alpha-like proteins in the Drosophila central nervous system. J Biol Chem (1989) 1.25
Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse. Proc Natl Acad Sci U S A (1987) 1.23
Adenylate cyclase and acetylcholine release regulated by separate serotonin receptors of somatic cell hybrids. Proc Natl Acad Sci U S A (1979) 1.23
A prospective trial evaluating a standard approach to reoperation for missed parathyroid adenoma. Ann Surg (1996) 1.23