Published in Mol Cell Biol on December 01, 1986
Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci U S A (1987) 4.61
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes. Mol Cell Biol (1989) 4.47
Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters. Proc Natl Acad Sci U S A (1988) 2.90
A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes. Proc Natl Acad Sci U S A (1988) 2.71
The cell-specific enhancer of the mouse transthyretin (prealbumin) gene binds a common factor at one site and a liver-specific factor(s) at two other sites. Mol Cell Biol (1988) 2.03
Cell-specific expression in transgenic plants reveals nonoverlapping roles for chloroplast and cytosolic glutamine synthetase. Proc Natl Acad Sci U S A (1990) 1.94
Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12. J Bacteriol (1989) 1.85
Two blocks in Moloney murine leukemia virus expression in undifferentiated F9 embryonal carcinoma cells as determined by transient expression assays. J Virol (1989) 1.84
Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice. EMBO J (1990) 1.78
The upstream muscle-specific enhancer of the rat muscle creatine kinase gene is composed of multiple elements. Mol Cell Biol (1989) 1.73
Cell-specific transcriptional control of the mouse DNA-binding protein mC/EBP. Proc Natl Acad Sci U S A (1989) 1.66
Promoter upstream elements of the chicken cardiac myosin light-chain 2-A gene interact with trans-acting regulatory factors for muscle-specific transcription. Mol Cell Biol (1989) 1.63
Differential binding of interferon-induced factors to an oligonucleotide that mediates transcriptional activation. Nucleic Acids Res (1989) 1.62
A cell-specific enhancer of the mouse alpha 1-antitrypsin gene has multiple functional regions and corresponding protein-binding sites. Mol Cell Biol (1988) 1.61
Positive and negative regulatory elements in the mouse albumin enhancer. Proc Natl Acad Sci U S A (1989) 1.58
A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat. Proc Natl Acad Sci U S A (1990) 1.55
The rat albumin promoter: cooperation with upstream elements is required when binding of APF/HNF1 to the proximal element is partially impaired by mutation or bacterial methylation. Mol Cell Biol (1989) 1.53
Transcriptional stimulation by CaPO4-DNA precipitates. Nucleic Acids Res (1988) 1.47
Overlap between pdxA and ksgA in the complex pdxA-ksgA-apaG-apaH operon of Escherichia coli K-12. J Bacteriol (1989) 1.47
Chromatin structures of the rat tyrosine aminotransferase gene relate to the function of its cis-acting elements. Mol Cell Biol (1990) 1.46
NMR detection of creatine kinase expressed in liver of transgenic mice: determination of free ADP levels. Proc Natl Acad Sci U S A (1990) 1.45
Divergent transcription of pdxB and homology between the pdxB and serA gene products in Escherichia coli K-12. J Bacteriol (1989) 1.40
Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region. Nucleic Acids Res (1991) 1.40
Different cis-acting DNA elements control expression of the human apolipoprotein AI gene in different cell types. Mol Cell Biol (1988) 1.35
Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotein lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes. Mol Cell Biol (1988) 1.35
Splice site selection dominates over poly(A) site choice in RNA production from complex adenovirus transcription units. EMBO J (1988) 1.34
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression. Mol Cell Biol (1994) 1.31
The trmA promoter has regulatory features and sequence elements in common with the rRNA P1 promoter family of Escherichia coli. J Bacteriol (1991) 1.25
Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice. Am J Physiol Endocrinol Metab (2008) 1.23
The mouse albumin enhancer contains a negative regulatory element that interacts with a novel DNA-binding protein. Mol Cell Biol (1990) 1.12
Interaction of a liver-specific factor with an enhancer 4.8 kilobases upstream of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol (1990) 1.10
Analysis of the upstream elements of the xenobiotic compound-inducible and positionally regulated glutathione S-transferase Ya gene. Mol Cell Biol (1990) 1.08
Two adjacent C/EBP-binding sequences that participate in the cell-specific expression of the mouse serum amyloid A3 gene. Mol Cell Biol (1990) 1.04
Positional and developmental regulation of glutamine synthetase expression in mouse liver. Mol Cell Biol (1988) 1.02
The transcription factor LF-A1 interacts with a bipartite recognition sequence in the promoter regions of several liver-specific genes. Nucleic Acids Res (1991) 0.98
Regulation of mouse serum amyloid A gene expression in transfected hepatoma cells. Mol Cell Biol (1990) 0.94
Genetic approach for intracerebroventricular delivery. Proc Natl Acad Sci U S A (2010) 0.88
The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice. J Neurosci (2014) 0.87
A small regulatory element from chromosome 19 enhances liver-specific gene expression. Gene Ther (2008) 0.87
Differential requirements for cellular enhancers in stem and differentiated cells. Nucleic Acids Res (1988) 0.87
Hepatic transcription of the acute-phase alpha 1-inhibitor III gene is controlled by a novel combination of cis-acting regulatory elements. Mol Cell Biol (1990) 0.87
Negative and positive cis-acting elements control the expression of murine alpha 1-protease inhibitor genes. Mol Cell Biol (1990) 0.86
The analysis of the human hemopexin promoter defines a new class of liver-specific genes. Nucleic Acids Res (1989) 0.85
Hepatocyte nuclear factor-4α interacts with other hepatocyte nuclear factors in regulating transthyretin gene expression. FEBS J (2010) 0.83
Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt). Hum Genet (2014) 0.78
Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid. Exp Mol Med (2010) 0.78
Molecular cloning of the mouse CCK gene: expression in different brain regions and during cortical development. Nucleic Acids Res (1991) 0.78
Network insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: a review. Curr Drug Discov Technol (2013) 0.77
The impact of minimally oversized adeno-associated viral vectors encoding human factor VIII on vector potency in vivo. Mol Ther Methods Clin Dev (2016) 0.76
Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System. Front Neurosci (2017) 0.75
Characteristics of Minimally Oversized Adeno-Associated Virus Vectors Encoding Human Factor VIII Generated Using Producer Cell Lines and Triple Transfection. Hum Gene Ther Methods (2017) 0.75
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Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Organization and expression of eucaryotic split genes coding for proteins. Annu Rev Biochem (1981) 49.46
A catalogue of splice junction sequences. Nucleic Acids Res (1982) 39.41
Mapping of RNA by a modification of the Berk-Sharp procedure: the 5' termini of 15 S beta-globin mRNA precursor and mature 10 s beta-globin mRNA have identical map coordinates. Nucleic Acids Res (1979) 31.23
The structure and evolution of the human beta-globin gene family. Cell (1980) 21.24
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell (1981) 20.72
A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. Cell (1983) 20.32
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell (1983) 18.86
Immunoglobulin gene transcription is activated by downstream sequence elements. Cell (1983) 15.53
Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science (1980) 13.44
Transcriptional control in the production of liver-specific mRNAs. Cell (1981) 9.35
Cell-specific expression controlled by the 5'-flanking region of insulin and chymotrypsin genes. Nature (1984) 8.65
Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements. Science (1985) 8.44
Fine structure genetic analysis of a beta-globin promoter. Science (1986) 6.36
Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus. Nature (1982) 6.02
Extracellular nucleases of pseudomonas BAL 31. III. Use of the double-strand deoxyriboexonuclease activity as the basis of a convenient method for the mapping of fragments of DNA produced by cleavage with restriction enzymes. Nucleic Acids Res (1978) 5.62
The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence. Cell (1984) 5.10
Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 A. J Mol Biol (1978) 4.47
Transcriptional 'enhancers' from SV40 and polyoma virus show a cell type preference. Nucleic Acids Res (1982) 3.94
Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell (1984) 3.56
Beta + thalassemia: aberrant splicing results from a single point mutation in an intron. Cell (1981) 3.51
Amyloid fibril protein related to prealbumin in familial amyloidotic polyneuropathy. Proc Natl Acad Sci U S A (1978) 3.10
Tissue-specific expression is conferred by a sequence from the 5' end of the rat albumin gene. EMBO J (1984) 3.07
Cell-specific expression of a transfected human alpha 1-antitrypsin gene. Cell (1985) 2.99
Multiple regulatory elements in the intergenic region between the alpha-fetoprotein and albumin genes. Mol Cell Biol (1986) 2.83
Cytomorphometry of developing rat liver and its application to enzymic differentiation. J Cell Biol (1972) 2.81
Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. Nature (1985) 2.77
Definition of essential sequences and functional equivalence of elements downstream of the adenovirus E2A and the early simian virus 40 polyadenylation sites. Mol Cell Biol (1985) 2.65
Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice. Cell (1984) 2.59
Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin). J Clin Invest (1984) 2.41
Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice. Proc Natl Acad Sci U S A (1985) 2.22
The lysozyme enhancer: cell-specific activation of the chicken lysozyme gene by a far-upstream DNA element. EMBO J (1986) 2.19
Enzymic differentiation in mammalian liver injection of fetal rats with hormones causes the premature formation of liver enzymes. Science (1969) 2.18
Identification of amyloid prealbumin variant in familial amyloidotic polyneuropathy (Japanese type). Biochem Biophys Res Commun (1983) 2.16
The interaction of thyroxine with human plasma prealbumin and with the prealbumin-retinol-binding protein complex. J Biol Chem (1969) 1.88
Rat transthyretin (prealbumin). Molecular cloning, nucleotide sequence, and gene expression in liver and brain. J Biol Chem (1985) 1.87
Primary structure of an amyloid prealbumin and its plasma precursor in a heredofamilial polyneuropathy of Swedish origin. Proc Natl Acad Sci U S A (1984) 1.74
Observations concerning the binding of thyroid hormones by human serum prealbumin. J Clin Invest (1963) 1.73
Cellular promoters incorporated into the adenovirus genome: cell specificity of albumin and immunoglobulin expression. Mol Cell Biol (1986) 1.73
Transcriptional and post-transcriptional control of specific messenger RNAs in adult and embryonic liver. J Mol Biol (1984) 1.63
Structure of the human prealbumin gene. J Biol Chem (1985) 1.58
Structure of the chromosomal gene for human serum prealbumin. Gene (1985) 1.40
Parameters of thyroid function in serum of 16 selected vertebrate species: a study of PBI, serum T4, free T4, and the pattern of T4 and T3 binding to serum proteins. Endocrinology (1970) 1.38
Cloning and sequence analysis of cDNA for human prealbumin. Biochem Biophys Res Commun (1984) 1.26
Vitamin A transport in rat plasma. Isolation and characterization or retinol-binding protein. J Biol Chem (1972) 1.18
Isolation and characterization of the alpha 1-antitrypsin gene of mice. DNA (1986) 1.12
Structural genes of the mouse major urinary protein are on chromosome 4. J Cell Biol (1982) 1.10
Studies on the transport and cellular distribution of vitamin A in normal and vitamin A-deficient rats with special reference to the vitamin A-binding plasma protein. J Biol Chem (1973) 1.10
DNase I-hypersensitive sites in the 5'-flanking region of the rat serum albumin gene: correlation between chromatin structure and transcriptional activity. Proc Natl Acad Sci U S A (1986) 1.00
A variant prealbumin-related low molecular weight amyloid fibril protein in familial amyloid polyneuropathy of Japanese origin. Biochem Biophys Res Commun (1984) 1.00
Cellular promoters incorporated into the adenovirus genome: effects of viral regulatory elements on transcription rates and cell specificity of albumin and beta-globin promoters. Mol Cell Biol (1986) 0.99
The three thyroxine-binding proteins in rat serum: binding capacities and effects of binding inhibitors. Endocrinology (1970) 0.87
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Evidence for virus-specific noncapsid proteins in poliovirus-infected HeLa cells. Proc Natl Acad Sci U S A (1965) 11.84
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science (1994) 11.33
An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA. Proc Natl Acad Sci U S A (1971) 11.01
Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA. Science (1971) 10.54
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell (1995) 10.16
Variety in the level of gene control in eukaryotic cells. Nature (1982) 9.61
Transcriptional control in the production of liver-specific mRNAs. Cell (1981) 9.35
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem (1995) 8.52
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature (1993) 7.56
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science (1993) 6.44
The role of STATs in transcriptional control and their impact on cellular function. Oncogene (2000) 6.42
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Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science (1992) 6.09
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The primary transcription unit of the mouse beta-major globin gene. Cell (1981) 5.75
Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science (1992) 5.71
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci U S A (1992) 5.50
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. Genes Dev (1989) 5.09
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Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci U S A (1987) 4.61
Identification of the membrane protein and "core" protein of Sindbis virus. Proc Natl Acad Sci U S A (1968) 4.52
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Sindbis virus infection of chick and hamster cells: synthesis of virus-specific proteins. Virology (1969) 4.38
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Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction. J Biol Chem (1986) 3.63
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Regulation of the primary expression of the early adenovirus transcription units. J Virol (1979) 2.92
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Identification of a Stat gene that functions in Drosophila development. Cell (1996) 2.90
Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc Natl Acad Sci U S A (1994) 2.85
Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron (1995) 2.83
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Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain. Neuron (1992) 2.79
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Globin RNA transcription: a possible termination site and demonstration of transcriptional control correlated with altered chromatin structure. Cell (1982) 2.72
Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol Cell Biol (1992) 2.72
Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. Mol Cell Biol (1991) 2.71
Processing of adenovirus specific nuclear RNA during virus replication. Virology (1972) 2.71
A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes. Proc Natl Acad Sci U S A (1988) 2.71