Published in J Biol Chem on January 05, 1988
A glucose transport protein expressed predominately in insulin-responsive tissues. Proc Natl Acad Sci U S A (1989) 2.98
Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. J Clin Invest (1989) 1.89
Mutational analysis of the SNF3 glucose transporter of Saccharomyces cerevisiae. Mol Cell Biol (1990) 1.89
Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: effect of chronic insulin and tolbutamide treatment. Proc Natl Acad Sci U S A (1989) 1.60
Sequence and structure of the yeast galactose transporter. J Bacteriol (1989) 1.58
Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level. Biochem J (1990) 1.41
The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am J Pathol (1990) 1.40
Pancreatic beta cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: a potentially general technique for isolating physiologically representative cell lines. Mol Cell Biol (1993) 1.34
Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression. J Clin Invest (1991) 1.28
Differential targeting of two glucose transporters from Leishmania enriettii is mediated by an NH2-terminal domain. J Cell Biol (1995) 1.19
Functional expression of mammalian glucose transporters in Xenopus laevis oocytes: evidence for cell-dependent insulin sensitivity. Mol Cell Biol (1989) 1.14
Physiological characterization of putative high-affinity glucose transport protein Hxt2 of Saccharomyces cerevisiae by use of anti-synthetic peptide antibodies. J Bacteriol (1993) 1.10
Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocation. J Clin Invest (1992) 1.09
Differential regulation of adipose tissue glucose transporters in genetic obesity (fatty rat). Selective increase in the adipose cell/muscle glucose transporter (GLUT 4) expression. J Clin Invest (1991) 1.02
Effect of denervation on the expression of two glucose transporter isoforms in rat hindlimb muscle. J Clin Invest (1991) 1.01
Development of the hormone-sensitive glucose transport activity in differentiating 3T3-L1 murine fibroblasts. Role of the two transporter species and their subcellular localization. Biochem J (1990) 0.99
Mechanisms and time course of impaired skeletal muscle glucose transport activity in streptozocin diabetic rats. J Clin Invest (1995) 0.98
Site-specific antibodies as probes of the topology and function of the human erythrocyte glucose transporter. Biochem J (1990) 0.90
Glucose transporters are abundant in cells with "occluding" junctions at the blood-eye barriers. Proc Natl Acad Sci U S A (1990) 0.87
Benchmarking B-cell epitope prediction for the design of peptide-based vaccines: problems and prospects. J Biomed Biotechnol (2010) 0.85
Structural isoforms of a membrane transport protein from Leishmania enriettii. Mol Cell Biol (1990) 0.82
Islet transplantation under the kidney capsule fully corrects the impaired skeletal muscle glucose transport system of streptozocin diabetic rats. J Clin Invest (1996) 0.81
A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs. Mol Cell Biol (1991) 0.79
Studies of renal injury. II. Activation of the glucose transporter 1 (GLUT1) gene and glycolysis in LLC-PK1 cells under Ca2+ stress. J Clin Invest (1996) 0.75
Differential control of the functional cell surface expression and content of hexose transporter GLUT-1 by glucose and glucose metabolism in murine fibroblasts. Biochem J (1993) 0.75
The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev (2000) 11.65
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell (1996) 11.02
A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature (1997) 9.71
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature (1997) 8.38
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature (1998) 8.33
Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature (1986) 7.81
Protein phosphorylation. Annu Rev Biochem (1975) 6.71
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature (1982) 6.56
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev (1988) 6.23
RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell (1991) 5.89
Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature (1989) 5.68
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature (1983) 5.20
Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature (1990) 5.20
Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells. J Biol Chem (1978) 4.93
Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev (1999) 4.92
Complex transcriptional units: diversity in gene expression by alternative RNA processing. Annu Rev Biochem (1986) 4.73
Functional domains of the human glucocorticoid receptor. Cell (1986) 4.68
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype. Cell (1988) 4.57
Transcription factor-specific requirements for coactivators and their acetyltransferase functions. Science (1998) 4.55
Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. Proc Natl Acad Sci U S A (1986) 4.40
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. J Biol Chem (1987) 4.32
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature (1982) 4.30
The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell (1991) 4.27
Regulation of neuronal traits by a novel transcriptional complex. Neuron (2001) 4.02
Phosphorylation activates the insulin receptor tyrosine protein kinase. Proc Natl Acad Sci U S A (1983) 3.94
The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements. Cell (1988) 3.91
Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature (1995) 3.90
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev (1998) 3.79
Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature (1987) 3.75
Co-activators and co-repressors in the integration of transcriptional responses. Curr Opin Cell Biol (1998) 3.51
Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell (2000) 3.47
Retinoic acid and thyroid hormone induce gene expression through a common responsive element. Nature (1988) 3.42
Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell (1989) 3.24
Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature (1996) 3.21
After insulin binds. Science (1987) 3.16
I-POU: a POU-domain protein that inhibits neuron-specific gene activation. Nature (1991) 3.15
Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science (2000) 3.14
Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell (1989) 3.12
Transcriptional activation by NF-kappaB requires multiple coactivators. Mol Cell Biol (1999) 3.11
ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol Cell Biol (1998) 3.06
Nuclear receptor coactivators. Curr Opin Cell Biol (1997) 2.96
The histone deacetylase-3 complex contains nuclear receptor corepressors. Proc Natl Acad Sci U S A (2000) 2.92
Molecular determinants of nuclear receptor-corepressor interaction. Genes Dev (1999) 2.92
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science (1990) 2.92
Molecular basis of the little mouse phenotype and implications for cell type-specific growth. Nature (1993) 2.83
Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature (1996) 2.81
The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell (1990) 2.78
Identification of human glucocorticoid receptor complementary DNA clones by epitope selection. Science (1985) 2.77
Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. Science (1984) 2.75
Effect of dibutyryladenosine 3':5'-cyclic monophosphate on growth and differentiation in Caulobacter crescentus. Proc Natl Acad Sci U S A (1972) 2.73
Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature (1998) 2.65
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature (1999) 2.64
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci U S A (1997) 2.63
Calcium-regulated phosphorylation within the leucine zipper of C/EBP beta. Science (1992) 2.61
SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell (1998) 2.60
Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression. Cell (1987) 2.58
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc Natl Acad Sci U S A (1998) 2.55
POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev (1997) 2.48
A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains. Mol Cell Biol (1996) 2.47
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature (1994) 2.43
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev (1990) 2.41
Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta. Proc Natl Acad Sci U S A (1982) 2.40
Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution. J Cell Biol (1982) 2.37
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins. Genes Dev (1997) 2.35
Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites. Mol Cell Biol (1984) 2.35
Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor. Science (1988) 2.34
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms. Cell (1986) 2.31
Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol (1980) 2.30
Acquisition of increased hormone sensitivity during in vitro adipocyte development. J Biol Chem (1977) 2.23
Signal-specific co-activator domain requirements for Pit-1 activation. Nature (1998) 2.22
Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product. Nature (1986) 2.18
Regulation of somatic growth by the p160 coactivator p/CIP. Proc Natl Acad Sci U S A (2000) 2.17
The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. J Biol Chem (1991) 2.15
Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate. J Biol Chem (1985) 2.15
Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates. J Biol Chem (1990) 2.13
Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A (1987) 2.13
A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature (1987) 2.11
Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev (1993) 2.11
Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature (1998) 2.10
Differential use of CREB binding protein-coactivator complexes. Science (1998) 2.10
Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain. Neuron (1993) 2.10
Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies. Cell (1988) 2.08
Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev (1998) 2.02
Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem (1998) 2.02
Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev (1996) 2.02
Molecular forms and subunit composition of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase purified from bovine heart muscle. J Biol Chem (1972) 1.99
Epidermal growth factor rapidly stimulates prolactin gene transcription. Nature (1982) 1.97
Alternative RNA processing: determining neuronal phenotype. Science (1984) 1.97
Glucose transporters serve as water channels. Proc Natl Acad Sci U S A (1990) 1.95
Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2. Nat Genet (2000) 1.90
Activation of S6 kinase activity in 3T3-L1 cells by insulin and phorbol ester. Proc Natl Acad Sci U S A (1985) 1.89
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J Biol Chem (1993) 1.88
Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development. Genes Dev (1999) 1.88
Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain. Cell (1988) 1.87
POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter. Genes Dev (1991) 1.84
Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor. Nature (1989) 1.84
Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature (1996) 1.84
Control of alternative pre-mRNA splicing by distributed pentameric repeats. Proc Natl Acad Sci U S A (1997) 1.82
Glucose deprivation and hexose transporter polypeptides of murine fibroblasts. J Biol Chem (1986) 1.81
Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth. Nature (1993) 1.80