Ionizing radiation as an initiator: effects of proliferation and promotion time on tumor incidence in mice.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 3677101)

Published in Cancer Res on December 15, 1987

Authors

D Jaffe1, G T Bowden

Author Affiliations

1: Department of Radiation Oncology, University of Arizona Medical Center, Tucson 85724.

Articles by these authors

(truncated to the top 100)

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature (1984) 4.28

The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc Natl Acad Sci U S A (1986) 2.28

Epidermal growth factor. Ability of tumor promoter to alter its degradation, receptor affinity and receptor number. J Biol Chem (1980) 1.65

Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice. Cancer Res (1993) 1.45

Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis. Curr Cancer Drug Targets (2007) 1.41

Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes. Oncogene (2001) 1.36

Expression of metalloproteinase genes in human prostate cancer. J Cancer Res Clin Oncol (1991) 1.31

Increased ROS levels contribute to elevated transcription factor and MAP kinase activities in malignantly progressed mouse keratinocyte cell lines. Carcinogenesis (1999) 1.31

Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice. Cancer Res (1981) 1.26

Expression pattern of a gene for a secreted metalloproteinase during late stages of tumor progression. Mol Carcinog (1988) 1.24

A set of cassette cloning vectors for rapid and versatile adaptation of restriction fragments. Biotechniques (1991) 1.21

Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors. Proc Natl Acad Sci U S A (1992) 1.20

Secreted phosphoprotein mRNA is induced during multi-stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts. Int J Cancer (1990) 1.18

Stromelysin/transin and tumor progression. Semin Cancer Biol (1990) 1.17

UVB irradiation-induced activator protein-1 activation correlates with increased c-fos gene expression in a human keratinocyte cell line. J Biol Chem (1998) 1.13

Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma. J Cell Biochem Suppl (1994) 1.12

Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice. Cell Growth Differ (1994) 1.12

Chemoprevention of human actinic keratoses by topical 2-(difluoromethyl)-dl-ornithine. Cancer Epidemiol Biomarkers Prev (2000) 1.09

Dose-response studies on the ability of 7,12-dimethylbenz(alpha)anthracene and benz(alpha)anthracene to initiate skin tumors. J Natl Cancer Inst (1974) 1.08

Inhibition of ultraviolet B-induced activator protein-1 (AP-1) activity by aspirin in AP-1-luciferase transgenic mice. J Biol Chem (1997) 1.08

Mitogen- and stress-activated protein kinase 1 mediates activation of Akt by ultraviolet B irradiation. J Biol Chem (2001) 1.08

Activation of p38 MAP kinase and ERK are required for ultraviolet-B induced c-fos gene expression in human keratinocytes. Oncogene (1999) 1.07

Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo. Carcinogenesis (1991) 1.07

Roles of Akt and glycogen synthase kinase 3beta in the ultraviolet B induction of cyclooxygenase-2 transcription in human keratinocytes. Cancer Res (2001) 1.05

Cleavage of beta 4 integrin by matrilysin. Exp Cell Res (1997) 1.04

Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes. Oncogene (2001) 1.04

Ultraviolet B-induced activated protein-1 activation does not require epidermal growth factor receptor but is blocked by a dominant negative PKClambda/iota. J Biol Chem (1996) 1.03

Hyperpigmentation and melanocytic hyperplasia in transgenic mice expressing the human T24 Ha-ras gene regulated by a mouse tyrosinase promoter. Mol Carcinog (1995) 1.03

Effects of acute and subchronic exposure of topically applied fullerene extracts on the mouse skin. Toxicol Ind Health (1994) 1.03

p53 Phosphorylation: biochemical and functional consequences. Life Sci (1997) 1.03

Extracellular signal-regulated kinase 1/2-mediated phosphorylation of JunD and FosB is required for okadaic acid-induced activator protein 1 activation. J Biol Chem (1999) 1.02

A switch from stromal to tumor cell expression of stromelysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression. Mol Carcinog (1994) 1.01

Attenuation of catalase activity in the malignant phenotype plays a functional role in an in vitro model for tumor progression. Cancer Lett (2001) 1.01

Overexpression of three ubiquitin genes in mouse epidermal tumors is associated with enhanced cellular proliferation and stress. Cell Growth Differ (1992) 0.98

Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation. Cancer Res (1998) 0.97

Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin. Biochem J (1998) 0.96

Inhibition of ultraviolet B--induced c-fos gene expression and p38 mitogen-activated protein kinase activation by (-)-epigallocatechin gallate in a human keratinocyte cell line. Mol Carcinog (1999) 0.96

Synthetic peptides inhibit adhesion of human tumor cells to extracellular matrix proteins. Cancer Res (2001) 0.95

Induction of melanoma in TPras transgenic mice. Carcinogenesis (1999) 0.95

Acetic acid, a potent stimulator of mouse epidermal macromolecular synthesis and hyperplasia but with weak tumor-promoting ability. J Natl Cancer Inst (1975) 0.94

Matrilysin expression in human prostate carcinoma. Mol Carcinog (1996) 0.94

Mechanism of synergistic induction of DNA synthesis by epidermal growth factor and tumor promoters. J Cell Physiol (1981) 0.93

Indirect induction of a clastogenic effect in epidermal cells by a tumor promoter. Carcinogenesis (1985) 0.93

Murine polyubiquitin mRNA sequence. Nucleic Acids Res (1990) 0.93

Interactions of mitomycin C with mammalian DNA detected by alkaline elution. Cancer Res (1985) 0.93

Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells. Mol Carcinog (1994) 0.92

Matrilysin expression in the involuting rat ventral prostate. Prostate (1996) 0.92

Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase. J Biol Chem (1997) 0.92

Characterization of the hepatic DNA damage caused by 1,2-dibromoethane using the alkaline elution technique. Carcinogenesis (1981) 0.91

Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis. Neoplasia (1999) 0.91

Quantitation of early clonal expansion of two mutant 61st codon c-Ha-ras alleles in DMBA/TPA treated mouse skin by nested PCR/RFLP. Carcinogenesis (1996) 0.90

Inhibition of ultraviolet B-induced AP-1 activation by theaflavins from black tea. Mol Carcinog (2000) 0.90

Okadaic acid induces the expression of both early and secondary response genes in mouse keratinocytes. Mol Carcinog (1992) 0.89

Tumor-specific overexpression of a novel keratinocyte lipid-binding protein. Identification and characterization of a cloned sequence activated during multistage carcinogenesis in mouse skin. J Biol Chem (1993) 0.88

EGF induces the expression of matrilysin in the human prostate adenocarcinoma cell line, LNCaP. Prostate (1999) 0.88

Regulation of DNA binding and transactivation in p53 by nuclear localization and phosphorylation. Oncogene (1997) 0.87

Tumor promoter-induced inhibition of epidermal growth factor binding to cultured mouse primary epidermal cells. Cancer Res (1981) 0.87

Role of p38 mitogen-activated protein kinases in ultraviolet-B irradiation-induced activator protein 1 activation in human keratinocytes. Mol Carcinog (2000) 0.86

Degradation of fibronectin fibrils by matrilysin and characterization of the degradation products. Exp Cell Res (1995) 0.86

Tumor promoters induce a transient expression of tumor-associated genes in both basal and differentiated cells of the mouse epidermis. Carcinogenesis (1988) 0.86

Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors. Int J Cancer (2001) 0.86

Interleukin-1beta secreted from monocytic cells induces the expression of matrilysin in the prostatic cell line LNCaP. J Biol Chem (1997) 0.86

DNA excision repair in ultraviolet-irradiated normal and malignantly transformed mouse epidermal cell cultures. Cancer Res (1977) 0.86

Cisplatin as an initiating agent in two-stage mouse skin carcinogenesis. Cancer Lett (1985) 0.86

(-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity. Carcinogenesis (1998) 0.85

Interleukin-1beta-induced promatrilysin expression is mediated by NFkappaB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP. Neoplasia (2002) 0.85

Okadaic acid stimulated TRE binding activity in a papilloma producing mouse keratinocyte cell line involves increased AP-1 expression. Oncogene (1996) 0.85

The effects of several croton oil constituents on two types of DNA repair and cyclic nucleotide levels in mammalian cells in vitro. Chem Biol Interact (1975) 0.85

Integrin- and cadherin-mediated induction of the matrix metalloprotease matrilysin in cocultures of malignant oral squamous cell carcinoma cells and dermal fibroblasts. Exp Cell Res (2001) 0.85

Comparative molecular pharmacology in leukemic L1210 cells of the anthracene anticancer drugs mitoxantrone and bisantrene. Cancer Res (1985) 0.85

Identification and quantitation of intracellular retinol and retinoic acid binding proteins in cultured cells. Biochim Biophys Acta (1984) 0.84

Effects of acute and chronic arsenic exposure of human-derived keratinocytes in an In Vitro human skin equivalent system: a novel model of human arsenicism. Toxicol In Vitro (2010) 0.84

Inhibition of atypical PKC blocks ultraviolet-induced AP-1 activation by specifically inhibiting ERKs activation. Mol Carcinog (2000) 0.84

Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures. Exp Cell Res (1994) 0.84

Prostate tumor cell invasion: a comparison of orthotopic and ectopic models. Invasion Metastasis (1993) 0.83

New relationships between prostatic intraepithelial neoplasia and prostatic carcinoma. J Cell Biochem Suppl (1992) 0.83

Macromolecular synthesis following a single application of alkylating agents used as initiators of mouse skin tumorigenesis. Cancer Res (1973) 0.83

Covalent DNA-protein crosslinking occurs after hyperthermia and radiation. Radiat Res (1983) 0.83

The effect of croton oil pretreatment on skin tumor initiation in mice. Cancer Res (1969) 0.83

Pharmacology of mitoxantrone: mode of action and pharmacokinetics. Invest New Drugs (1985) 0.83

Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane. Mol Carcinog (1989) 0.82

Ionizing radiation enhances malignant progression of mouse skin tumors. Carcinogenesis (1987) 0.82

Expression of the transin, c-fos, and c-jun genes in rat transplantable osteosarcomas and malignant fibrous histiocytomas. Mol Carcinog (1992) 0.82

Fibroblast-directed expression and localization of 92-kDa type IV collagenase along the tumor-stroma interface in an in vitro three-dimensional model of human squamous cell carcinoma. Mol Carcinog (1997) 0.82

Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide. Mol Carcinog (1999) 0.81

7,12-Dimethylbenz[a]anthracene-induced mouse keratinocyte malignant transformation independent of Harvey ras activation. J Invest Dermatol (1993) 0.81

Altered surface expression and increased turnover of the alpha6beta4 integrin in an undifferentiated carcinoma. Carcinogenesis (2000) 0.81

Effects of the tumor promoter TPA on the induction of DNA synthesis in normal and RSV-transformed rat fibroblasts. J Supramol Struct (1979) 0.81

Deuterium isotope effect on the metabolism and toxicity of 1,2-dibromoethane. Toxicol Appl Pharmacol (1983) 0.81

Inhibitory effects of deferoxamine on UVB-induced AP-1 transactivation. Carcinogenesis (1999) 0.81

Modification of keratin by the chemotherapeutic drug mitoxantrone. Biochem Pharmacol (1988) 0.81

Stability of sulforaphane for topical formulation. Drug Dev Ind Pharm (2013) 0.80

Characterization of hepatic DNA damage induced in rats by the pyrrolizidine alkaloid monocrotaline. Cancer Res (1984) 0.80

Inhibition of p38 MAP kinase increases okadaic acid mediated AP-1 expression and DNA binding but has no effect on TRE dependent transcription. Oncogene (1999) 0.80

Laminin-5-mediated gene expression in human prostate carcinoma cells. Mol Carcinog (2001) 0.79

Promatrilysin expression is induced by fibroblast growth factors in the prostatic carcinoma cell line LNCaP but not in normal primary prostate epithelial cells. Prostate (1999) 0.79

Differential expression of matrix metalloproteinases in activated c-ras-Ha-transfected immortalized human keratinocytes. Br J Cancer (1998) 0.79

Postreplication repair of DNA in ultraviolet light-irradiated normal and malignancy transformed mouse epidermal cell cultures. Cancer Res (1978) 0.79

Expression of beta-actin during progression of mouse skin tumors. Carcinogenesis (1989) 0.79

Regulation of matrilysin expression in cells of squamous cell carcinoma by E-cadherin-mediated cell-cell contact. J Cancer Res Clin Oncol (1997) 0.79