Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae.

PubWeight™: 8.03‹?› | Rank: Top 0.1%

🔗 View Article (PMC 383491)

Published in Proc Natl Acad Sci U S A on April 01, 1979

Authors

P Novick, R Schekman

Articles citing this

(truncated to the top 100)

Diverse effects of beta-tubulin mutations on microtubule formation and function. J Cell Biol (1988) 6.88

The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J (1996) 6.26

Mechanisms of protein localization. Microbiol Rev (1983) 6.12

Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain. Proc Natl Acad Sci U S A (1996) 5.84

Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant. J Cell Biol (1991) 5.76

The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles. J Cell Biol (1991) 5.73

Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information. Mol Cell Biol (1988) 5.42

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J Cell Biol (1987) 4.94

Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae. J Cell Biol (1991) 4.54

Mutations in a new gene, secB, cause defective protein localization in Escherichia coli. J Bacteriol (1983) 4.35

Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport. EMBO J (1993) 4.27

Lyticase: endoglucanase and protease activities that act together in yeast cell lysis. J Bacteriol (1980) 4.25

Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme. J Cell Biol (1985) 4.24

Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation. EMBO J (1989) 4.19

Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect. J Cell Biol (1992) 4.14

An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proc Natl Acad Sci U S A (1983) 3.95

Sorting of soluble ER proteins in yeast. EMBO J (1988) 3.95

Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y. J Cell Biol (1986) 3.85

Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J Cell Biol (1993) 3.85

Localized secretion of acid phosphatase reflects the pattern of cell surface growth in Saccharomyces cerevisiae. J Cell Biol (1980) 3.84

Membrane fusion. Nat Struct Mol Biol (2008) 3.79

Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol Biol Cell (1992) 3.49

Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J Cell Biol (1994) 3.32

Sec1p binds to SNARE complexes and concentrates at sites of secretion. J Cell Biol (1999) 3.31

Central roles of small GTPases in the development of cell polarity in yeast and beyond. Microbiol Mol Biol Rev (2007) 3.30

A role for clathrin in the sorting of vacuolar proteins in the Golgi complex of yeast. EMBO J (1992) 3.10

The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants. EMBO J (1994) 3.10

Parallel secretory pathways to the cell surface in yeast. J Cell Biol (1995) 2.92

Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics. Mol Biol Cell (2000) 2.87

Yeast secretory mutants that block the formation of active cell surface enzymes. J Cell Biol (1984) 2.71

In vitro synthesis of repressible yeast acid phosphatase: identification of multiple mRNAs and products. Proc Natl Acad Sci U S A (1980) 2.70

Saccharomyces cerevisiae mannoproteins form an external cell wall layer that determines wall porosity. J Bacteriol (1984) 2.64

Purification and characterization of constitutive secretory vesicles from yeast. J Cell Biol (1987) 2.63

Selective and immediate effects of clathrin heavy chain mutations on Golgi membrane protein retention in Saccharomyces cerevisiae. J Cell Biol (1992) 2.60

Export of major cell surface proteins is blocked in yeast secretory mutants. J Cell Biol (1983) 2.58

nSec1 binds a closed conformation of syntaxin1A. J Cell Biol (2000) 2.44

Double-stranded ribonucleic acid killer systems in yeasts. Microbiol Rev (1984) 2.33

Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p. EMBO J (2002) 2.20

Effects of null mutations and overexpression of capping protein on morphogenesis, actin distribution and polarized secretion in yeast. J Cell Biol (1992) 2.18

COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants. J Cell Biol (1997) 2.16

The Sec15 protein responds to the function of the GTP binding protein, Sec4, to control vesicular traffic in yeast. J Cell Biol (1989) 2.11

Induction of apoplastic invertase of Chenopodium rubrum by D-glucose and a glucose analog and tissue-specific expression suggest a role in sink-source regulation. Plant Physiol (1995) 2.09

Ordering the final events in yeast exocytosis. J Cell Biol (2000) 2.03

Yeast vacuoles and membrane fusion pathways. EMBO J (2002) 1.98

Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes. J Cell Biol (2002) 1.92

A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis. Mol Biol Cell (2006) 1.88

Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain. J Cell Biol (1990) 1.86

The yeast actin-related protein Arp2p is required for the internalization step of endocytosis. Mol Biol Cell (1997) 1.83

A yeast t-SNARE involved in endocytosis. Mol Biol Cell (1998) 1.82

Sec15 protein, an essential component of the exocytotic apparatus, is associated with the plasma membrane and with a soluble 19.5S particle. J Cell Biol (1991) 1.82

AtVPS45 complex formation at the trans-Golgi network. Mol Biol Cell (2000) 1.78

Ammonia regulation of amino acid permeases in Saccharomyces cerevisiae. Mol Cell Biol (1983) 1.75

Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation. EMBO J (2001) 1.69

Functionally and spatially distinct modes of munc18-syntaxin 1 interaction. J Biol Chem (2007) 1.66

Identification of an essential Schizosaccharomyces pombe RNA homologous to the 7SL component of signal recognition particle. Mol Cell Biol (1988) 1.66

Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol (1996) 1.64

Genetic analysis of the Saccharomyces cerevisiae RHO3 gene, encoding a rho-type small GTPase, provides evidence for a role in bud formation. Genetics (1996) 1.59

PAK-family kinases regulate cell and actin polarization throughout the cell cycle of Saccharomyces cerevisiae. J Cell Biol (1999) 1.58

Retrograde lipid traffic in yeast: identification of two distinct pathways for internalization of fluorescent-labeled phosphatidylcholine from the plasma membrane. J Cell Biol (1993) 1.56

Yeast and mammals utilize similar cytosolic components to drive protein transport through the Golgi complex. Proc Natl Acad Sci U S A (1986) 1.56

Coincident localization of secretory and plasma membrane proteins in organelles of the yeast secretory pathway. J Bacteriol (1988) 1.55

Mutants of the yeast Yarrowia lipolytica defective in protein exit from the endoplasmic reticulum are also defective in peroxisome biogenesis. Mol Cell Biol (1998) 1.54

Yeast killer plasmid mutations affecting toxin secretion and activity and toxin immunity function. Mol Cell Biol (1982) 1.52

Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel. Proc Natl Acad Sci U S A (1993) 1.52

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex. Proc Natl Acad Sci U S A (2010) 1.51

Specific sterols required for the internalization step of endocytosis in yeast. Mol Biol Cell (1999) 1.48

Sec3p is involved in secretion and morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell (1997) 1.45

Multiple SNARE interactions of an SM protein: Sed5p/Sly1p binding is dispensable for transport. EMBO J (2004) 1.44

SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion. J Cell Biol (2010) 1.43

ER-golgi traffic is a prerequisite for efficient ER degradation. Mol Biol Cell (2002) 1.42

Four distinct secretory pathways serve protein secretion, cell surface growth, and peroxisome biogenesis in the yeast Yarrowia lipolytica. Mol Cell Biol (1997) 1.41

The role of the COOH terminus of Sec2p in the transport of post-Golgi vesicles. J Cell Biol (2000) 1.37

Secretory vesicles externalize the major plasma membrane ATPase in yeast. J Cell Biol (1988) 1.37

Munc18a scaffolds SNARE assembly to promote membrane fusion. Mol Biol Cell (2008) 1.36

vac2: a yeast mutant which distinguishes vacuole segregation from Golgi-to-vacuole protein targeting. EMBO J (1991) 1.36

A specific structural requirement for ergosterol in long-chain fatty acid synthesis mutants important for maintaining raft domains in yeast. Mol Biol Cell (2002) 1.32

A cell-free assay allows reconstitution of Vps33p-dependent transport to the yeast vacuole/lysosome. J Cell Biol (1999) 1.31

Fatty acid-acylated proteins in secretory mutants of Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.30

A random mutagenesis approach to isolate dominant-negative yeast sec1 mutants reveals a functional role for domain 3a in yeast and mammalian Sec1/Munc18 proteins. Genetics (2008) 1.29

Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins. Mol Cell Biol (1996) 1.28

Uptake of the ATP-binding cassette (ABC) transporter Ste6 into the yeast vacuole is blocked in the doa4 Mutant. Mol Biol Cell (2001) 1.27

The SM protein Car/Vps33A regulates SNARE-mediated trafficking to lysosomes and lysosome-related organelles. Mol Biol Cell (2009) 1.27

The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol (2003) 1.25

Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. PLoS One (2010) 1.24

The yeast GRD20 gene is required for protein sorting in the trans-Golgi network/endosomal system and for polarization of the actin cytoskeleton. Mol Biol Cell (1999) 1.23

Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles. Mol Cell Biol (2000) 1.23

Identification and characterization of a mouse cell mutant defective in the intracellular transport of glycoproteins. J Cell Biol (1987) 1.21

A nonprocessive class V myosin drives cargo processively when a kinesin- related protein is a passenger. Curr Biol (2009) 1.21

Ras regulates the polarity of the yeast actin cytoskeleton through the stress response pathway. Mol Biol Cell (2001) 1.20

Mechanisms and concepts paving the way towards a complete transport cycle of plant vacuolar sorting receptors. Plant Cell (2012) 1.19

Secretion of Saccharomyces cerevisiae killer toxin: processing of the glycosylated precursor. Mol Cell Biol (1983) 1.19

The effects of clathrin inactivation on localization of Kex2 protease are independent of the TGN localization signal in the cytosolic tail of Kex2p. Mol Biol Cell (1996) 1.18

MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast. Mol Biol Cell (1999) 1.18

The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. Proc Natl Acad Sci U S A (1993) 1.16

Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ. Proc Natl Acad Sci U S A (2013) 1.16

A novel Saccharomyces cerevisiae secretory mutant possesses a thermolabile phosphomannose isomerase. J Bacteriol (1991) 1.14

Effects of inositol starvation on phospholipid and glycan syntheses in Saccharomyces cerevisiae. J Bacteriol (1980) 1.13

Two distinct subfractions in isolated Saccharomyces cerevisiae plasma membranes. J Bacteriol (1983) 1.12

The exocyst complex in exocytosis and cell migration. Protoplasma (2011) 1.12

Clonal tests of conventional kinesin function during cell proliferation and differentiation. Mol Biol Cell (2000) 1.11

Articles cited by this

Intracellular aspects of the process of protein synthesis. Science (1975) 25.21

A Critical Evaluation of the Nitrogen Assimilation Tests Commonly Used in the Classification of Yeasts. J Bacteriol (1946) 16.78

Behavior of spindles and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiae. J Bacteriol (1975) 13.41

Beta-D-fructofuranoside fructohydrolase from yeast. Methods Enzymol (1975) 9.19

Endoplasmic reticulum as the initiator of bud formation in yeast (S. cerevisiae). Arch Mikrobiol (1967) 3.65

Biosynthesis of acid phosphatase of baker's yeast. Factors influencing its production by protoplasts and characterization of the secreted enzyme. Biochim Biophys Acta (1972) 2.79

Growth and metabolism of inositol-starved Saccharomyces cerevisiae. J Bacteriol (1977) 2.75

Localized deposition of chitin on the yeast cell surface in response to mating pheromone. Proc Natl Acad Sci U S A (1979) 2.55

Gene duplication in Saccharomyces cerevisiae. Genetics (1978) 2.41

Sulfate uptake in Saccharomyces cerevisiae: biochemical and genetic study. J Bacteriol (1977) 2.40

Localization of acid phosphatase in protoplasts from Saccharomyces cerevisiae. J Bacteriol (1975) 2.06

Isolation of glucanase-containing particles from budding Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1971) 1.97

Localization of acid phosphatase in Saccharomyces cerevisiae: a clue to cell wall formation. J Bacteriol (1977) 1.93

Cell-free activity of a sulfate binding site involved in active transport. Proc Natl Acad Sci U S A (1966) 1.92

Subcellular distribution of yeast invertase isoenzymes. Arch Microbiol (1975) 1.51

Effects of proteolytic enzymes on invertase secretion in sphaeroplasts of Saccharomyces: inhibition by trypsin. Can J Microbiol (1977) 1.17

Articles by these authors

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell (1980) 23.17

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene (1987) 19.68

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides. Nature (1988) 11.00

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell (1982) 10.55

Order of events in the yeast secretory pathway. Cell (1981) 10.13

COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell (1994) 10.01

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway. Cell (1990) 8.98

Phenotypic analysis of temperature-sensitive yeast actin mutants. Cell (1985) 8.53

RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form. Proc Natl Acad Sci U S A (1972) 8.09

A possible role for RNA polymerase in the initiation of M13 DNA synthesis. Proc Natl Acad Sci U S A (1971) 6.71

The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J (1996) 6.26

Initiation of DNA synthesis: synthesis of phiX174 replicative form requires RNA synthesis resistant to rifampicin. Proc Natl Acad Sci U S A (1972) 5.74

Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway. Cell (1984) 5.53

Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast. Cell (1981) 5.51

The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis. EMBO J (1999) 5.35

Vesicle-mediated protein sorting. Annu Rev Biochem (1992) 5.20

A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J Cell Biol (1987) 4.94

COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell (1998) 4.73

Reconstitution of SEC gene product-dependent intercompartmental protein transport. Cell (1988) 4.66

Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis. Cell (1994) 4.46

Lyticase: endoglucanase and protease activities that act together in yeast cell lysis. J Bacteriol (1980) 4.25

Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme. J Cell Biol (1985) 4.24

Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation. EMBO J (1989) 4.19

Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast. J Cell Biol (1989) 4.13

Phosphoinositides as regulators in membrane traffic. Science (1996) 4.13

The role of Myo2, a yeast class V myosin, in vesicular transport. J Cell Biol (1995) 4.11

An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proc Natl Acad Sci U S A (1983) 3.95

Localization of components involved in protein transport and processing through the yeast Golgi apparatus. J Cell Biol (1991) 3.86

Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J Cell Biol (1995) 3.85

Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y. J Cell Biol (1986) 3.85

Localized secretion of acid phosphatase reflects the pattern of cell surface growth in Saccharomyces cerevisiae. J Cell Biol (1980) 3.84

Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. Mol Biol Cell (1992) 3.81

Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae. Cell (1993) 3.67

Multienzyme systems of DNA replication. Science (1974) 3.66

The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J Cell Biol (1989) 3.57

Protein localization and membrane traffic in yeast. Annu Rev Cell Biol (1985) 3.51

Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin gene. Proc Natl Acad Sci U S A (1984) 3.47

Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes. Cell (1995) 3.44

A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast. J Cell Biol (1988) 3.37

Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum. Science (1993) 3.36

Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell (1998) 3.32

SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature (1993) 3.23

A protein interaction map for cell polarity development. J Cell Biol (2001) 3.23

Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex. Nature (1991) 3.21

COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature (1998) 3.20

Regulated import and degradation of a cytosolic protein in the yeast vacuole. Nature (1991) 3.12

The yeast phosphatidylinositol-4-OH kinase pik1 regulates secretion at the Golgi. Nat Cell Biol (1999) 3.01

SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer. Nature (1992) 2.99

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation. EMBO J (1997) 2.92

COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell (1995) 2.87

Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast. J Cell Biol (1988) 2.86

Spatial regulation of the exocyst complex by Rho1 GTPase. Nat Cell Biol (2001) 2.86

GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction. Proc Natl Acad Sci U S A (1990) 2.78

Clathrin: a role in the intracellular retention of a Golgi membrane protein. Science (1989) 2.75

Yeast secretory mutants that block the formation of active cell surface enzymes. J Cell Biol (1984) 2.71

A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome. J Cell Biol (1993) 2.65

Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro. EMBO J (1989) 2.64

Cdc42 interacts with the exocyst and regulates polarized secretion. J Biol Chem (2001) 2.62

A primer on vesicle budding. Cell (1999) 2.58

Export of major cell surface proteins is blocked in yeast secretory mutants. J Cell Biol (1983) 2.58

Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation. Mol Cell Biol (1992) 2.51

Genetic and biochemical characterization of clathrin-deficient Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.50

SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum. J Cell Biol (1989) 2.49

Ten proteins required for conversion of phiX174 single-stranded DNA to duplex form in vitro. Resolution and reconstitution. J Biol Chem (1975) 2.48

Dynamics of the COPII coat with GTP and stable analogues. Nat Cell Biol (2001) 2.44

A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. Proc Natl Acad Sci U S A (1973) 2.42

Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery. Mol Cell Biol (1990) 2.36

A test of clathrin function in protein secretion and cell growth. Science (1985) 2.36

SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus. J Biol Chem (1988) 2.35

GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae. J Bacteriol (1986) 2.30

Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. Proc Natl Acad Sci U S A (1991) 2.27

Actin from Saccharomyces cerevisiae. Mol Cell Biol (1982) 2.26

Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4. Nature (1993) 2.21

Protein complexes in transport vesicle targeting. Trends Cell Biol (2000) 2.15

Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes. Proc Natl Acad Sci U S A (1998) 2.15

Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs. Science (1998) 2.14

BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum. Proc Natl Acad Sci U S A (1995) 2.09

Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER. J Cell Biol (1991) 2.04

Purification and characterization of SAR1p, a small GTP-binding protein required for transport vesicle formation from the endoplasmic reticulum. J Biol Chem (1993) 2.04

The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein. J Biol Chem (1992) 2.03

ER export: public transportation by the COPII coach. Curr Opin Cell Biol (2001) 2.02

Exo84p is an exocyst protein essential for secretion. J Biol Chem (1999) 2.02

Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70. J Cell Biol (1993) 2.02

Genes required for completion of import of proteins into the endoplasmic reticulum in yeast. J Cell Biol (1984) 2.00

Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro. J Cell Biol (1993) 2.00

Characterization of a gene product (Sec53p) required for protein assembly in the yeast endoplasmic reticulum. J Cell Biol (1985) 1.97

Sec8p and Sec15p are components of a plasma membrane-associated 19.5S particle that may function downstream of Sec4p to control exocytosis. J Cell Biol (1992) 1.96

Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic. J Biol Chem (1994) 1.93

Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures. J Biol Chem (1998) 1.93

The role of GTP-binding proteins in transport along the exocytic pathway. Annu Rev Cell Biol (1993) 1.93

Invertase beta-galactosidase hybrid proteins fail to be transported from the endoplasmic reticulum in Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.91

Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiae. Mol Cell Biol (1992) 1.90

Chs6p-dependent anterograde transport of Chs3p from the chitosome to the plasma membrane in Saccharomyces cerevisiae. Mol Biol Cell (1998) 1.90

New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex. Genetics (1996) 1.89

Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae. J Cell Biol (2000) 1.87