Published in Mol Cell Biol on November 01, 1984
A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J Cell Biol (1987) 4.94
Uses of lac fusions for the study of biological problems. Microbiol Rev (1985) 4.38
Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme. J Cell Biol (1985) 4.24
The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J Cell Biol (1986) 4.07
Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product. Mol Cell Biol (1988) 3.74
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Physical map of the Saccharomyces cerevisiae genome at 110-kilobase resolution. Genetics (1991) 2.43
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A short domain of the plant vacuolar protein phytohemagglutinin targets invertase to the yeast vacuole. Plant Cell (1990) 1.91
Isolation and DNA sequence of ADH3, a nuclear gene encoding the mitochondrial isozyme of alcohol dehydrogenase in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.88
Secretion-defective mutations in the signal sequence for Saccharomyces cerevisiae invertase. Mol Cell Biol (1986) 1.66
Genetic studies on the inability of beta-galactosidase to be translocated across the Escherichia coli cytoplasmic membrane. J Bacteriol (1989) 1.61
Expression of the lacZ gene from two methanol-regulated promoters in Pichia pastoris. Nucleic Acids Res (1987) 1.57
The yeast cell fusion protein FUS1 is O-glycosylated and spans the plasma membrane. Proc Natl Acad Sci U S A (1989) 1.56
Coincident localization of secretory and plasma membrane proteins in organelles of the yeast secretory pathway. J Bacteriol (1988) 1.55
Reconstitution of transport of vesicular stomatitis virus G protein from the endoplasmic reticulum to the Golgi complex using a cell-free system. J Cell Biol (1987) 1.47
A vesicular intermediate in the transport of hepatoma secretory proteins from the rough endoplasmic reticulum to the Golgi complex. J Cell Biol (1987) 1.44
Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane. Mol Cell Biol (1986) 1.36
Characterization of the promoter, signal sequence, and amino terminus of a secreted beta-galactosidase from "Streptomyces lividans". J Bacteriol (1987) 1.18
Regulated expression of Sindbis and vesicular stomatitis virus glycoproteins in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1986) 0.98
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Signal processing, glycosylation, and secretion of mutant hemagglutinins of a human influenza virus by Saccharomyces cerevisiae. Mol Cell Biol (1987) 0.93
Metabolic engineering of Saccharomyces cerevisiae for lactose/whey fermentation. Bioeng Bugs (2009) 0.81
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Two differentially regulated mRNAs with different 5' ends encode secreted with intracellular forms of yeast invertase. Cell (1982) 25.10
Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell (1980) 23.17
Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components. J Cell Biol (1975) 15.47
Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell (1982) 10.55
Order of events in the yeast secretory pathway. Cell (1981) 10.13
Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1981) 9.45
Beta-D-fructofuranoside fructohydrolase from yeast. Methods Enzymol (1975) 9.19
Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm. J Bacteriol (1979) 6.38
Mutations that alter the signal sequence of alkaline phosphatase in Escherichia coli. J Bacteriol (1983) 6.27
Mechanisms of protein localization. Microbiol Rev (1983) 6.12
Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast. Cell (1981) 5.51
Yeast genes fused to beta-galactosidase in Escherichia coli can be expressed normally in yeast. Proc Natl Acad Sci U S A (1981) 4.79
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The secreted form of invertase in Saccharomyces cerevisiae is synthesized from mRNA encoding a signal sequence. Mol Cell Biol (1983) 3.96
An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proc Natl Acad Sci U S A (1983) 3.95
The amino acid sequence of beta-galactosidase of Escherichia coli. Proc Natl Acad Sci U S A (1977) 3.63
Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage lambda receptor. J Mol Biol (1980) 3.62
Presecretory and cytoplasmic invertase polypeptides encoded by distinct mRNAs derived from the same structural gene differ by a signal sequence. Proc Natl Acad Sci U S A (1982) 3.22
Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm. Nature (1979) 3.10
Regulation of HIS4-lacZ fusions in Saccharomyces cerevisiae. Mol Cell Biol (1982) 3.07
Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria. Proc Natl Acad Sci U S A (1984) 3.02
Nucleotide sequence of the yeast SUC2 gene for invertase. Nucleic Acids Res (1983) 2.86
Yeast secretory mutants that block the formation of active cell surface enzymes. J Cell Biol (1984) 2.71
Subunit structure of external invertase from Saccharomyces cerevisiae. J Biol Chem (1977) 2.59
Export of major cell surface proteins is blocked in yeast secretory mutants. J Cell Biol (1983) 2.58
Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein. Proc Natl Acad Sci U S A (1978) 2.37
Regulatory sites for his3 gene expression in yeast. Nature (1982) 2.09
Identification of a sequence responsible for periodic synthesis of yeast histone 2A mRNA. Proc Natl Acad Sci U S A (1982) 2.07
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Information within the mature LamB protein necessary for localization to the outer membrane of E coli K12. Cell (1983) 1.94
Genetic evidence for a silent SUC gene in yeast. Genetics (1981) 1.80
Fusion of the Saccharomyces cerevisiae leu2 gene to an Escherichia coli beta-galactosidase gene. Mol Cell Biol (1983) 1.56
Carbohydrate structure of yeast invertase. Demonstration of a form with only core oligosaccharides and a form with completed polysaccharide chains. J Biol Chem (1979) 1.27
Heat shock-regulated production of Escherichia coli beta-galactosidase in Saccharomyces cerevisiae. Mol Cell Biol (1983) 1.24
Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell (1980) 23.17
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Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol (1988) 13.27
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A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides. Nature (1988) 11.00
Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell (1982) 10.55
Order of events in the yeast secretory pathway. Cell (1981) 10.13
COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell (1994) 10.01
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell (2001) 9.08
Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway. Cell (1990) 8.98
RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form. Proc Natl Acad Sci U S A (1972) 8.09
Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1979) 8.03
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science (1993) 7.86
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J (1998) 7.68
The fungal vacuole: composition, function, and biogenesis. Microbiol Rev (1990) 6.98
A possible role for RNA polymerase in the initiation of M13 DNA synthesis. Proc Natl Acad Sci U S A (1971) 6.71
Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell (1994) 6.57
Suppressor mutations that restore export of a protein with a defective signal sequence. Cell (1981) 6.33
Mechanisms of protein localization. Microbiol Rev (1983) 6.12
Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell (1998) 6.07
Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease. Cell (1987) 5.92
Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant. J Cell Biol (1991) 5.76
Initiation of DNA synthesis: synthesis of phiX174 replicative form requires RNA synthesis resistant to rifampicin. Proc Natl Acad Sci U S A (1972) 5.74
Isolation of yeast mutants defective in protein targeting to the vacuole. Proc Natl Acad Sci U S A (1986) 5.71
Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway. Cell (1984) 5.53
Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast. Cell (1981) 5.51
Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information. Mol Cell Biol (1988) 5.42
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol (1990) 5.25
Vesicle-mediated protein sorting. Annu Rev Biochem (1992) 5.20
Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J (1989) 5.12
The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell (1994) 5.10
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p. EMBO J (1997) 5.05
A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J Cell Biol (1987) 4.94
Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J Cell Biol (1988) 4.90
COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell (1998) 4.73
Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol Biol Cell (1996) 4.71
Reconstitution of SEC gene product-dependent intercompartmental protein transport. Cell (1988) 4.66
In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor. Cell (1986) 4.59
Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast. Mol Biol Cell (1996) 4.58
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol (1998) 4.41
Lyticase: endoglucanase and protease activities that act together in yeast cell lysis. J Bacteriol (1980) 4.25
Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme. J Cell Biol (1985) 4.24
Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation. EMBO J (1989) 4.19
Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic (2000) 4.17
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Cell Biol (1997) 4.16
Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast. J Cell Biol (1989) 4.13
Phosphoinositides as regulators in membrane traffic. Science (1996) 4.13
The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J Cell Biol (1986) 4.07
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. Mol Cell (1998) 4.01
An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proc Natl Acad Sci U S A (1983) 3.95
Localization of components involved in protein transport and processing through the yeast Golgi apparatus. J Cell Biol (1991) 3.86
Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y. J Cell Biol (1986) 3.85
Localized secretion of acid phosphatase reflects the pattern of cell surface growth in Saccharomyces cerevisiae. J Cell Biol (1980) 3.84
Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. Mol Biol Cell (1992) 3.81
Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product. Mol Cell Biol (1988) 3.74
New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J Cell Biol (2000) 3.69
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Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage lambda receptor. J Mol Biol (1980) 3.62
Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products. J Cell Biol (1997) 3.61
The role of phosphoinositides in membrane transport. Curr Opin Cell Biol (2001) 3.57
The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex. J Cell Biol (1989) 3.55
Protein localization and membrane traffic in yeast. Annu Rev Cell Biol (1985) 3.51
A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J (1993) 3.49
Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes. Cell (1995) 3.44
A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast. J Cell Biol (1988) 3.37
Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum. Science (1993) 3.36
Sequence analysis of mutations that prevent export of lambda receptor, an Escherichia coli outer membrane protein. Nature (1980) 3.36
Targeted selection of recombinant clones through gene dosage effects. Proc Natl Acad Sci U S A (1983) 3.33
Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J Cell Biol (1994) 3.32
The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell (1997) 3.30
Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. Mol Cell (2000) 3.30
A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. Mol Biol Cell (1997) 3.27
Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment. J Cell Biol (1993) 3.25
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis. J Cell Biol (1998) 3.24
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature (1993) 3.23
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex. Nature (1991) 3.21
COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature (1998) 3.20
Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol (1995) 3.16
Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes. Nat Cell Biol (2001) 3.14
Regulated import and degradation of a cytosolic protein in the yeast vacuole. Nature (1991) 3.12
Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria. Proc Natl Acad Sci U S A (1984) 3.02
SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer. Nature (1992) 2.99
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Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation. EMBO J (1997) 2.92
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VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J (1994) 2.90
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell (1995) 2.87
Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics. Mol Biol Cell (2000) 2.87
Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast. J Cell Biol (1988) 2.86
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A previously unidentified gene in the spc operon of Escherichia coli K12 specifies a component of the protein export machinery. Cell (1982) 2.84
Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking. Mol Cell Biol (1998) 2.80
GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction. Proc Natl Acad Sci U S A (1990) 2.78
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Yeast secretory mutants that block the formation of active cell surface enzymes. J Cell Biol (1984) 2.71