Published in J Biol Chem on August 25, 1974
Stable thiobarbituric acid chromophore with dimethyl sulphoxide. Application to sialic acid assay in analytical de-O-acetylation. Biochem J (1976) 2.19
CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. Biochem J (1981) 1.91
Topography of N-CAM structural and functional determinants. I. Classification of monoclonal antibody epitopes. J Cell Biol (1986) 1.35
Description and characterization of a surface lectin from Giardia lamblia. Infect Immun (1986) 1.28
Origin of slow and fast oscillations of Ca2+ in mouse pancreatic islets. J Physiol (1998) 1.17
Human alpha-fetoprotein as a modulator of human lymphocyte transformation: correlation of biological potency with electrophoretic variants. Proc Natl Acad Sci U S A (1976) 1.05
The endoplasmic reticulum is a glucose-modulated high-affinity sink for Ca2+ in mouse pancreatic beta-cells. J Physiol (2001) 0.99
Calcium uptake by subcellular fractions of pancreatic islets. Effects of nucleotides and theophylline. Biochem J (1976) 0.97
Calcium and pancreatic beta-cell function. The mechanism of insulin secretion studied with the aid of lanthanum. Biochem J (1980) 0.90
External ATP mimics carbachol in initiating calcium mobilization from pancreatic beta-cells conditioned by previous exposure to glucose. Br J Pharmacol (1987) 0.88
Evidence for co-transport of sodium, potassium and chloride in mouse pancreatic islets. J Physiol (1988) 0.85
Effect of intracellular alkalinization on pancreatic islet calcium uptake and insulin secretion. Biochem J (1986) 0.84
Inhibition by hydrochlorothiazide of insulin release and calcium influx in mouse pancreatic beta-cells. Br J Pharmacol (1993) 0.82
Manganese accumulation in pancreatic beta-cells and its stimulation by glucose. Biochem J (1982) 0.81
Comparison of the effects of perchlorate and Bay K 8644 on the dynamics of cytoplasmic Ca2+ concentration and insulin secretion in mouse beta-cells. Biochem J (1996) 0.79
Relationships between the Na(+)/K(+) pump and ATP and ADP content in mouse pancreatic islets: effects of meglitinide and glibenclamide. Br J Pharmacol (2000) 0.79
The interaction between manganese and calcium fluxes in pancreatic beta-cells. Biochem J (1983) 0.79
Effect of perchlorate on calcium uptake and insulin secretion in mouse pancreatic islets. Biochem J (1987) 0.77
Islet autoantibodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age. Diabetologia (1999) 2.81
The preparation of, and studies on, free cell suspensions from mouse pancreatic islets. Diabetologia (1974) 2.69
Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Nature (1982) 2.58
Autoimmune type 1 diabetes: resolved and unresolved issues. J Clin Invest (2001) 2.35
Studies in obese-hyperglycemic mice. Ann N Y Acad Sci (1965) 2.17
A genetic linkage map of the laboratory rat, Rattus norvegicus. Nat Genet (1995) 2.10
A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM. Diabetologia (1994) 2.03
HLA-D region beta-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals. Nature (1983) 1.99
CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. Biochem J (1981) 1.91
Genetic dissection of autoimmune type I diabetes in the BB rat. Nat Genet (1992) 1.87
Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens (2007) 1.77
The pancreatic beta-cell recognition of insulin secretagogues. Effects of calcium and sodium on glucose metabolism and insulin release. Biochem J (1974) 1.76
The World Health Organization International Collaborative Study for islet cell antibodies. Diabetologia (2000) 1.74
Family cell lines available for research. Am J Hum Genet (1990) 1.72
Interferon expression in the pancreases of patients with type I diabetes. Diabetes (1995) 1.69
Evidence for mediated transport of glucose in mammalian pancreatic -cells. Biochim Biophys Acta (1971) 1.69
Etiological diagnosis of primary adrenal insufficiency using an original flowchart of immune and biochemical markers. J Clin Endocrinol Metab (1998) 1.63
Synchronous oscillations of cytoplasmic Ca2+ and insulin release in glucose-stimulated pancreatic islets. J Biol Chem (1994) 1.62
The significance of calcium for glucose stimulation of insulin release. Endocrinology (1975) 1.60
Islet-cell-surface antibodies in juvenile diabetes mellitus. N Engl J Med (1978) 1.59
Toxic effects of cyclosporine on the endocrine pancreas of Wistar rats. Transplantation (1986) 1.59
Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands. J Immunol Methods (1995) 1.51
Preparation and characterization of plasma membrane-enriched fractions from rat pancreatic islets. J Cell Biol (1976) 1.50
Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. J Clin Invest (1996) 1.49
Prognostic factors for the course of beta cell function in autoimmune diabetes. J Clin Endocrinol Metab (2000) 1.48
Human cell lines from families available for diabetes research. Diabetologia (1991) 1.44
Dual effects of glucose on the cytosolic Ca2+ activity of mouse pancreatic beta-cells. FEBS Lett (1984) 1.42
Glucose-induced decrease in Rb+ permeability in pancreatic beta cells. Nature (1975) 1.40
Cloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones. J Cell Biol (1986) 1.39
Association between HLA and islet cell antibodies in diabetic patients with a mitochondrial DNA mutation at base pair 3243. Diabetologia (1996) 1.38
Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients. Diabetes (1999) 1.38
Glutamate decarboxylase (GAD65) and tyrosine phosphatase-like protein (IA-2) autoantibodies index in a regional population is related to glucose intolerance and body mass index. Diabetologia (1999) 1.37
Adenosine triphosphate levels of mammalian pancreatic B cells after stimulation with glucose and hypoglycemic sulfonylureas. Diabetes (1969) 1.36
Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets. J Cell Biol (1999) 1.34
Glutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children. J Clin Invest (1995) 1.33
Propagation of cytoplasmic Ca2+ oscillations in clusters of pancreatic beta-cells exposed to glucose. Cell Calcium (1991) 1.33
Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro. Biochem J (1979) 1.32
Antibodies to a Mr-64,000 islet cell protein in Swedish children with newly diagnosed type 1 (insulin-dependent) diabetes. Diabetologia (1988) 1.32
Autoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat. Science (1984) 1.31
Glucose-induced oscillations of cytoplasmic Ca2+ in the pancreatic beta-cell. Biochem Biophys Res Commun (1988) 1.30
Transport of rubidium and sodium in pancreatic islets. J Physiol (1974) 1.29
Human class II major histocompatibility antigen beta-chains are derived from at least three loci. Nature (1983) 1.29
Block in insulin release from column-perifused pancreatic beta-cells induced by islet cell surface antibodies and complement. Diabetes (1981) 1.25
The pancreatic beta-cell recognition of insulin secretagogues: does cyclic AMP mediate the effect of glucose? Proc Natl Acad Sci U S A (1974) 1.24
Effects of glucose on 45Ca2+ uptake by pancreatic islets as studied with the lanthanum method. J Physiol (1976) 1.23
Calcium uptake by pancreatic -cells as measured with the aid of 45 Ca and mannitol- 3 H. Am J Physiol (1971) 1.23
Effects of glucose and other modifiers of insulin release on the oxidative metabolism of amino acids in micro-dissected pancreatic islets. Biochem J (1971) 1.23
[Isolated mouse islets as a model for studying insulin release]. Acta Diabetol Lat (1972) 1.21
Superoxide dismutase is a prophylactic against alloxan diabetes. Nature (1981) 1.20
The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone. Arch Biochem Biophys (1974) 1.20
HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls. Am J Hum Genet (1993) 1.19
A major loss in islet mass and B-cell function precedes hyperglycemia in mice given multiple low doses of streptozotocin. Diabetes (1981) 1.19
Transport of -aminoisobutyric acid in mammalian pancretic -cells. Diabetologia (1971) 1.19
Immunology in diabetes: an update. Diabetes Metab Rev (1998) 1.18
Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ. J Clin Invest (1987) 1.17
Origin of slow and fast oscillations of Ca2+ in mouse pancreatic islets. J Physiol (1998) 1.17
Suppression of Ca2+ oscillations in glucagon-producing alpha 2-cells by insulin/glucose and amino acids. Biochim Biophys Acta (1996) 1.16
Iodoacetamide-induced sensitization of the pancreatic beta-cells to glucose stimulation. Biochem J (1973) 1.16
Three types of cytoplasmic Ca2+ oscillations in stimulated pancreatic beta-cells. Arch Biochem Biophys (1989) 1.15
Islet cell surface and lymphocyte antibodies often precede the spontaneous diabetes in the BB rat. Diabetologia (1984) 1.15
High diagnostic accuracy for idiopathic Addison's disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase. J Clin Endocrinol Metab (1995) 1.14
Targeting of the 67-kDa isoform of glutamic acid decarboxylase to intracellular organelles is mediated by its interaction with the NH2-terminal region of the 65-kDa isoform of glutamic acid decarboxylase. J Biol Chem (1995) 1.14
Voltage-activated currents in guinea pig pancreatic alpha 2 cells. Evidence for Ca2+-dependent action potentials. J Gen Physiol (1988) 1.14
Sometimes it's hot, sometimes it's not. Nat Genet (1998) 1.14
Antibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with autoimmune polyendocrine syndrome type I. J Clin Endocrinol Metab (1996) 1.13
Characterization of the inositol 1,4,5-trisphosphate-induced Ca2+ release in pancreatic beta-cells. Biochem J (1987) 1.13
Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase. Diabetes (1993) 1.13
The pancreatic -cell recognition of insulin secretagogues. IV. Islet uptake of sulfonylureas. Diabetologia (1973) 1.12
Effects of organic mercurials on mammalian pancreatic -cells. Insulin release, glucose transport, glucose oxidation, membrane permeability and ultrastructure. Biochem J (1972) 1.11
Ca2+ oscillations in pancreatic islet cells secreting glucagon and somatostatin. Biochem Biophys Res Commun (1995) 1.10
GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65. Diabetes (2000) 1.10
Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets. Diabetes (1993) 1.10