A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM.

PubWeight™: 2.03‹?› | Rank: Top 2%

🔗 View Article (PMID 8063033)

Published in Diabetologia on April 01, 1994

Authors

C E Grubin1, T Daniels, B Toivola, M Landin-Olsson, W A Hagopian, L Li, A E Karlsen, E Boel, B Michelsen, A Lernmark

Author Affiliations

1: Department of Medicine, University of Washington, Seattle.

Articles citing this

Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1. Diabetes Care (2009) 2.91

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care (2011) 2.75

GAD2 on chromosome 10p12 is a candidate gene for human obesity. PLoS Biol (2003) 1.83

IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus. Proc Natl Acad Sci U S A (1996) 1.71

Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes (2010) 1.67

Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect. J Clin Invest (1997) 1.30

Frequency, immunogenetics, and clinical characteristics of latent autoimmune diabetes in China (LADA China study): a nationwide, multicenter, clinic-based cross-sectional study. Diabetes (2012) 1.19

Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy. J Autoimmun (2010) 1.10

Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens. Clin Immunol (2008) 1.06

No association of vitamin D intake or 25-hydroxyvitamin D levels in childhood with risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). Diabetologia (2011) 1.03

Longitudinal changes in epitope recognition of autoantibodies against glutamate decarboxylase 65 (GAD65Ab) in prediabetic adults developing diabetes. Clin Exp Immunol (2007) 1.02

Islet autoantigens: structure, function, localization, and regulation. Cold Spring Harb Perspect Med (2012) 1.02

Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study. Diabetes (2012) 1.01

Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia. Orphanet J Rare Dis (2011) 0.98

Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden. Int J Obes (Lond) (2011) 0.95

Simple screening method for autoantigen proteins using the N-terminal biotinylated protein library produced by wheat cell-free synthesis. J Proteome Res (2010) 0.94

Detection of four diabetes specific autoantibodies in a single radioimmunoassay: an innovative high-throughput approach for autoimmune diabetes screening. Clin Exp Immunol (2011) 0.94

A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease. PLoS One (2013) 0.93

The association between the PTPN22 1858C>T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies. Genes Immun (2010) 0.91

Investigation of the vitamin D receptor gene (VDR) and its interaction with protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2) on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). J Steroid Biochem Mol Biol (2012) 0.89

Detection of candidal antigens in autoimmune polyglandular syndrome type I. Clin Diagn Lab Immunol (1996) 0.89

Evidence for immunological priming and increased frequency of CD4+ CD25+ cord blood T cells in children born to mothers with type 1 diabetes. Clin Exp Immunol (2006) 0.88

The effect of age on insulin sensitivity and insulin secretion in first-degree relatives of type 1 diabetic patients: a population analysis. J Clin Endocrinol Metab (2009) 0.87

How to diagnose and classify diabetes in primary health care: lessons learned from the Diabetes Register in Northern Sweden (DiabNorth). Scand J Prim Health Care (2012) 0.86

Changes in GAD65Ab-specific antiidiotypic antibody levels correlate with changes in C-peptide levels and progression to islet cell autoimmunity. J Clin Endocrinol Metab (2010) 0.85

Photopheresis at onset of type 1 diabetes: a randomised, double blind, placebo controlled trial. Arch Dis Child (2001) 0.85

GAD65 autoantibodies and its role as biomarker of Type 1 diabetes and Latent Autoimmune Diabetes in Adults (LADA). Drugs Future (2011) 0.84

Evidence of stage- and age-related heterogeneity of non-HLA SNPs and risk of islet autoimmunity and type 1 diabetes: the diabetes autoimmunity study in the young. Clin Dev Immunol (2013) 0.84

Autoimmunity to glutamic acid decarboxylase in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). Clin Exp Immunol (2000) 0.83

Altered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiency. Clin Exp Immunol (2010) 0.82

Ketosis-onset diabetes and ketosis-prone diabetes: same or not? Int J Endocrinol (2013) 0.81

Increased prevalence of autoimmune thyroid disease in patients with type 1 diabetes. Korean J Intern Med (2000) 0.81

Modulation of diabetes in NOD mice by GAD65-specific monoclonal antibodies is epitope specific and accompanied by anti-idiotypic antibodies. Immunology (2007) 0.81

Evidence for oligogenic inheritance of type 1 diabetes in a large Bedouin Arab family. J Clin Invest (1998) 0.81

Autoantibody epitopes to the smaller isoform of glutamate decarboxylase do not differ in Swedish and Japanese type 1 diabetes patients and may be associated with high-risk human leucocyte antigen class II alleles. Clin Exp Immunol (2007) 0.81

Altered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA). Clin Exp Immunol (2016) 0.80

Reduction of tissue transglutaminase autoantibody levels by gluten-free diet is associated with changes in subsets of peripheral blood lymphocytes in children with newly diagnosed coeliac disease. Clin Exp Immunol (2006) 0.80

Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein. J Immunol Methods (2008) 0.79

Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young. Diabetologia (2013) 0.79

p73 overexpression and nuclear accumulation in hepatitis C virus-associated hepatocellular carcinoma. Dig Dis Sci (2002) 0.79

Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotransmission and affect motor learning and behavioral functions. Front Behav Neurosci (2015) 0.79

Decline in titers of anti-idiotypic antibodies specific to autoantibodies to GAD65 (GAD65Ab) precedes development of GAD65Ab and type 1 diabetes. PLoS One (2013) 0.79

Masked and overt autoantibodies specific to the DPD epitope of 65-kDa glutamate decarboxylase (GAD65-DPD) are associated with preserved β-cell functional reserve in ketosis-prone diabetes. J Clin Endocrinol Metab (2014) 0.78

Association between vitamin D metabolism gene polymorphisms and risk of islet autoimmunity and progression to type 1 diabetes: the diabetes autoimmunity study in the young (DAISY). J Clin Endocrinol Metab (2013) 0.78

The glutamic acid decarboxylase 65 immunoglobulin G subclass profile differs between adult-onset type 1 diabetes and latent autoimmune diabetes in adults (LADA) up to 3 years after clinical onset. Clin Exp Immunol (2009) 0.78

Expression of GAD67 and novel GAD67 splice variants during human fetal pancreas development: GAD67 expression in the fetal pancreas. Endocr Pathol (2007) 0.77

Molecular biology of IDDM. Diabetologia (1994) 0.77

GAD autoantibody epitope pattern after GAD-alum treatment in children and adolescents with type 1 diabetes. Pediatr Diabetes (2011) 0.77

Effect of photopheresis on lymphocyte population in children with newly diagnosed type 1 diabetes. Clin Diagn Lab Immunol (2004) 0.77

Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies. Genes Immun (2015) 0.76

Relationship between Ljungan virus antibodies, HLA-DQ8, and insulin autoantibodies in newly diagnosed type 1 diabetes children. Viral Immunol (2013) 0.76

Assessing age-related etiologic heterogeneity in the onset of islet autoimmunity. Biomed Res Int (2015) 0.75

Determination of glutamic acid decarboxylase antibodies (GADA) IgG subclasses - comparison of three immunoprecipitation assays (IPAs). Clin Exp Immunol (2007) 0.75

Danish children born with glutamic acid decarboxylase-65 and islet antigen-2 autoantibodies at birth had an increased risk to develop type 1 diabetes. Eur J Endocrinol (2010) 0.75

Increased inflammation is associated with islet autoimmunity and type 1 diabetes in the Diabetes Autoimmunity Study in the Young (DAISY). PLoS One (2017) 0.75

Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development. Diabetes Care (2017) 0.75

Osteoprotegerin autoantibodies do not predict low bone mineral density in middle-aged women. Bone Rep (2017) 0.75

Articles by these authors

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell (2000) 11.90

Role of LXRs in control of lipogenesis. Genes Dev (2000) 6.98

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science (2000) 6.52

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19

Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ Res (2001) 5.08

The GA5 locus of Arabidopsis thaliana encodes a multifunctional gibberellin 20-oxidase: molecular cloning and functional expression. Proc Natl Acad Sci U S A (1995) 4.80

Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science (2013) 4.17

The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake. Cell (1994) 4.12

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci U S A (2000) 4.08

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proc Natl Acad Sci U S A (1998) 3.99

Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care (1998) 3.99

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation (2001) 3.98

Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol (1991) 3.82

Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment. J Virol (2001) 3.40

Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron (2001) 3.37

Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci U S A (2000) 3.24

Determinants of car travel on daily journeys to school: cross sectional survey of primary school children. BMJ (1998) 3.11

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737. Oncogene (2006) 3.10

Activity of neurons in anterior inferior temporal cortex during a short-term memory task. J Neurosci (1993) 3.04

Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects. Clin Pharmacol Ther (2009) 2.98

Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin Pharmacol Ther (2009) 2.96

New tricks for modelers from the crystallography toolkit: the particle mesh Ewald algorithm and its use in nucleic acid simulations. Structure (1999) 2.92

A neural mechanism for working and recognition memory in inferior temporal cortex. Science (1991) 2.86

Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83

Islet autoantibodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age. Diabetologia (1999) 2.81

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell (1995) 2.78

Global gene expression profiles of Bacillus subtilis grown under anaerobic conditions. J Bacteriol (2000) 2.77

Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature (2001) 2.76

Prism adaptation to a rightward optical deviation rehabilitates left hemispatial neglect. Nature (1998) 2.74

The preparation of, and studies on, free cell suspensions from mouse pancreatic islets. Diabetologia (1974) 2.69

From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A (2001) 2.66

Multiple novel astrovirus species in human stool. J Gen Virol (2009) 2.63

Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science (1993) 2.62

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Nature (1982) 2.58

Analysis of trends in deaths from accidental drug poisoning in teenagers, 1985-95. BMJ (1997) 2.44

Fluorescence and photobleaching dynamics of single light-harvesting complexes. Proc Natl Acad Sci U S A (1997) 2.42

Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. Circulation (1999) 2.40

Implications of a new dietary measurement error model for estimation of relative risk: application to four calibration studies. Am J Epidemiol (1999) 2.40

Influence of changing travel patterns on child death rates from injury: trend analysis. BMJ (1997) 2.37

Molecular cloning and photoperiod-regulated expression of gibberellin 20-oxidase from the long-day plant spinach. Plant Physiol (1996) 2.36

Autoimmune type 1 diabetes: resolved and unresolved issues. J Clin Invest (2001) 2.35

Molecular cloning of human gastrin cDNA: evidence for evolution of gastrin by gene duplication. Proc Natl Acad Sci U S A (1983) 2.35

Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure. J Biol Chem (2001) 2.32

Phylogeny of the Simbu serogroup of the genus Bunyavirus. J Gen Virol (2001) 2.30

A role for destabilizing amino acid replacements in light-chain amyloidosis. Proc Natl Acad Sci U S A (1994) 2.27

Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nat Cell Biol (1999) 2.25

Overview of the MHC fine mapping data. Diabetes Obes Metab (2009) 2.24

Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment. J Virol (2000) 2.24

Cardiac defects and renal failure in mice with targeted mutations in Pkd2. Nat Genet (2000) 2.24

The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev (1998) 2.23

Disturbed sleep: effects of sociocultural factors and illness. Arch Dis Child (1998) 2.23

The looming epidemic of diabetes-associated tuberculosis: learning lessons from HIV-associated tuberculosis. Int J Tuberc Lung Dis (2011) 2.19

Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking. Nat Genet (1996) 2.18

Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur J Neurol (2012) 2.18

Coniferyl aldehyde 5-hydroxylation and methylation direct syringyl lignin biosynthesis in angiosperms. Proc Natl Acad Sci U S A (1999) 2.17

Human albumin solution for resuscitation and volume expansion in critically ill patients. Cochrane Database Syst Rev (2002) 2.15

A genetic linkage map of the bovine genome. Nat Genet (1994) 2.15

Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inhibition by anti-C5 therapy. Circulation (1998) 2.14

Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes (2007) 2.13

Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development. Proc Natl Acad Sci U S A (1997) 2.12

A genetic linkage map of the laboratory rat, Rattus norvegicus. Nat Genet (1995) 2.10

KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit. Proc Natl Acad Sci U S A (1998) 2.07

Peroral endoscopic remyotomy for failed Heller myotomy: a prospective single-center study. Endoscopy (2013) 2.04

A systematic review of therapeutic interventions to reduce acute and chronic post-surgical pain after amputation, thoracotomy or mastectomy. Eur J Pain (2014) 2.03

Laparoscopic versus open total mesorectal excision with anal sphincter preservation for low rectal cancer. Surg Endosc (2004) 2.01

Field evaluation of the Computer Science and Applications, Inc. physical activity monitor. Med Sci Sports Exerc (2000) 1.99

Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial. Osteoarthritis Cartilage (2010) 1.99

HLA-D region beta-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals. Nature (1983) 1.99

Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells. Nat Med (1998) 1.98

Attributable causes of cancer in China. Ann Oncol (2012) 1.98

Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population. Int J Oral Maxillofac Surg (2009) 1.98

Shanxi Province Cervical Cancer Screening Study: a cross-sectional comparative trial of multiple techniques to detect cervical neoplasia. Gynecol Oncol (2001) 1.93

Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor. J Biol Chem (2000) 1.91

Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation (2001) 1.90

Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease. Am J Psychiatry (1990) 1.87

Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells. Toxicol Sci (2000) 1.87

Genetic dissection of autoimmune type I diabetes in the BB rat. Nat Genet (1992) 1.87

Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity. Kidney Int (2008) 1.86

Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2. Cancer Res (2000) 1.85

Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway. Nat Struct Biol (2000) 1.85

A medium-density genetic linkage map of the bovine genome. Mamm Genome (1997) 1.85

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature (1995) 1.81

The use of propranolol in the treatment of infantile haemangiomas: an update on potential mechanisms of action. Br J Dermatol (2014) 1.80

FMR1 CGG repeat length predicts motor dysfunction in premutation carriers. Neurology (2007) 1.80

Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding. Mol Cell Biol (1991) 1.79

A randomized, prospective trial of rituximab for acute rejection in pediatric renal transplantation. Am J Transplant (2008) 1.79

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens (2007) 1.77

Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair. Mol Cell Biol (2001) 1.76

The pancreatic beta-cell recognition of insulin secretagogues. Effects of calcium and sodium on glucose metabolism and insulin release. Biochem J (1974) 1.76

Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice. Proc Natl Acad Sci U S A (1995) 1.75

Serologic association between human papillomavirus type 16 infection and esophageal cancer in Shaanxi Province, China. J Natl Cancer Inst (1996) 1.75

Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10. Proc Natl Acad Sci U S A (1991) 1.74

Human albumin solution for resuscitation and volume expansion in critically ill patients. Cochrane Database Syst Rev (2004) 1.74

The World Health Organization International Collaborative Study for islet cell antibodies. Diabetologia (2000) 1.74

Systematic review of the concurrent and predictive validity of MRI biomarkers in OA. Osteoarthritis Cartilage (2011) 1.73

Family cell lines available for research. Am J Hum Genet (1990) 1.72

Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency. Proc Natl Acad Sci U S A (1998) 1.70

Interferon expression in the pancreases of patients with type I diabetes. Diabetes (1995) 1.69

A phase II trial of oral diethylstilbesterol as a second-line hormonal agent in advanced prostate cancer. Urology (1998) 1.69