Published in Eur J Biochem on December 01, 1969
Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping. Nucleic Acids Res (1974) 19.42
Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides. Nucleic Acids Res (1977) 8.92
Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA. Proc Natl Acad Sci U S A (1973) 7.11
Evidence for crossing-over between avian tumor viruses based on analysis of viral RNAs. Proc Natl Acad Sci U S A (1974) 4.40
Efficient expression of Escherichia coli galactokinase gene in mammalian cells. Proc Natl Acad Sci U S A (1982) 4.25
Effect of colicin E3 upon the 30S ribosomal subunit of Escherichia coli. Proc Natl Acad Sci U S A (1971) 4.12
Rapid synthesis of oligodeoxyribonucleotides: a new solid-phase method. Nucleic Acids Res (1977) 3.77
Pyrimidine sequences from the DNA of bacteriophages fd, fl, and phi X174. Proc Natl Acad Sci U S A (1972) 3.73
Ending the message: poly(A) signals then and now. Genes Dev (2011) 3.47
Avian tumor virus RNA: a comparison of three sarcoma viruses and their transformation-defective derivatives by oligonucleotide fingerprinting and DNA-RNA hybridization. Proc Natl Acad Sci U S A (1973) 3.46
Ribonucleic acid components of murine sarcoma and leukemia viruses. Proc Natl Acad Sci U S A (1973) 3.42
Nucleotide sequences of nuclear U1A RNAs from chicken, rat and man. Nucleic Acids Res (1980) 3.13
Bacterial ribosome. Bacteriol Rev (1970) 2.88
Nucleotide sequences of 4.5S RNAs associated with poly(A)-containing RNAs of mouse and hamster cells. Nucleic Acids Res (1980) 2.70
A restriction endonuclease from Staphylococcus aureus. Nucleic Acids Res (1976) 2.67
The nucleotide sequence of the intergenic region between the 5.8S and 26S rRNA genes of the yeast ribosomal RNA operon. Possible implications for the interaction between 5.8S and 26S rRNA and the processing of the primary transcript. Nucleic Acids Res (1981) 2.67
Chromatography of nucleic acid digests on thin layers of cellulose impregnated with polyethyleneimine. Biochem J (1971) 2.66
Some characteristics of processing sites in ribosomal precursor RNA of yeast. Nucleic Acids Res (1980) 2.65
The nucleotide sequence at the termini of adenovirus type 5 DNA. Nucleic Acids Res (1977) 2.61
Nucleotide sequences from tryptophan messenger RNA of Escherichia coli: the sequence corresponding to the amino-terminal region of the first polypeptide specified by the operon. Proc Natl Acad Sci U S A (1973) 2.58
A rho-dependent termination site in the gene coding for tyrosine tRNA su3 of Escherichia coli. Nature (1978) 2.58
Chemical synthesis of a self-complementary octanucleotide, dG-G-T-T-A-A-C-C by a modified triester method. Nucleic Acids Res (1978) 2.56
The nucleotide sequence preceding an RNA polymerase initiation site on SV40 DNA. Part 2. The sequence of the early strand transcript. Nucleic Acids Res (1974) 2.40
Nucleotide sequence at the binding site for coat protein on RNA of bacteriophage R17. Proc Natl Acad Sci U S A (1972) 2.38
RNA of replication-defective strains of Rous sarcoma virus. Proc Natl Acad Sci U S A (1975) 2.37
Nucleotide sequences of RNA transcribed in infected cells and by Escherichia coli RNA polymerase from a segment of simian virus 40 DNA. Proc Natl Acad Sci U S A (1974) 2.34
Joining of ribooligonucleotides with T4 RNA ligase and identification of the oligonucleotide-adenylate intermediate. Nucleic Acids Res (1976) 2.31
The structure of tandem regulatory regions in the deo operon of Escherichia coli K12. EMBO J (1982) 2.28
ClaI. a new restriction endonuclease from Caryophanon latum L. Nucleic Acids Res (1981) 2.21
A specific endonuclease from Bacillus caldolyticus. Nucleic Acids Res (1978) 2.18
A rapid and convenient synthesis of poly-thymidylic acid by the modified triester approach. Nucleic Acids Res (1977) 2.15
A nucleotide sequence from a ribonuclease III processing site in bacteriophage T7 RNA. Proc Natl Acad Sci U S A (1977) 2.04
Genomic complexities of murine leukemia and sarcoma, reticuloendotheliosis, and visna viruses. J Virol (1976) 2.01
Nucleotide sequence in the promoter region of the Escherichia coli tyrosine tRNA gene. Proc Natl Acad Sci U S A (1974) 2.01
Defined transversion mutations at a specific position in DNA using synthetic oligodeoxyribonucleotides as mutagens. Nucleic Acids Res (1979) 1.99
The nuclear 5S RNAs from chicken, rat and man. U5 RNAs are encoded by multiple genes. Nucleic Acids Res (1981) 1.96
Rapid synthesis of oligodeoxyribonucleotides on a grafted polymer support. Nucleic Acids Res (1979) 1.87
The 7S RNA from tomato leaf tissue resembles a signal recognition particle RNA and exhibits a remarkable sequence complementarity to viroids. EMBO J (1988) 1.84
Two new restriction endonucleases from Proteus vulgaris. Nucleic Acids Res (1981) 1.84
Experimental approaches to identify non-coding RNAs. Nucleic Acids Res (2006) 1.80
Use of specific endonuclease cleavage in RNA sequencing. Nucleic Acids Res (1977) 1.77
Genetic analysis of the processing of a spliced tRNA. EMBO J (1982) 1.67
Total synthesis of a RNA molecule with sequence identical to that of Escherichia coli formylmethionine tRNA. Proc Natl Acad Sci U S A (1981) 1.63
Determination of nucleotide sequences beyond the sites of transcriptional termination. Proc Natl Acad Sci U S A (1976) 1.61
Purification, properties and specificity of the restriction endonuclease from Bacillus stearothermophilus. Biochem J (1979) 1.58
A spite specific endonuclease from thermus thermophilus 111, Tth111I. Nucleic Acids Res (1980) 1.57
A second site-specific restriction endonuclease from Staphylococcus aureus. Nucleic Acids Res (1978) 1.56
Isolation and sequence determination of the 3'-terminal regions of isotopically labelled RNA molecules. Nucleic Acids Res (1974) 1.53
Ultrafast sequencing of oligodeoxyribonucleotides by FAB-mass spectrometry. Nucleic Acids Res (1982) 1.53
A second site specific endonuclease from Thermus thermophilus 111, Tth111II. Nucleic Acids Res (1980) 1.51
Nucleotide sequence surrounding a ribonuclease III processing site in bacteriophage T7 RNA. Proc Natl Acad Sci U S A (1977) 1.50
The primary transcript of the ribosomal repeating unit in yeast. Nucleic Acids Res (1979) 1.48
Chemical and enzymatic synthesis of lactose operator of Escherichia coli and its binding to lactose repressor. Proc Natl Acad Sci U S A (1976) 1.48
The nucleotide sequence preceding an RNA polymerase initiation site on SV40 DNA. Part 1. The sequence of the late strand transcript. Nucleic Acids Res (1974) 1.48
Specific cleavage of ribosomal RNA caused by alpha sarcin. Nucleic Acids Res (1977) 1.45
ScrFI: a new sequence-specific endonuclease from Streptococcus cremoris. Nucleic Acids Res (1982) 1.45
Solid-phase methods for sequencing of nucleic acids I. Simultaneous sequencing of different oligodeoxyribonucleotides using a new, mechanically stable anion-exchange paper. Nucleic Acids Res (1985) 1.44
Sequence of the 3'-terminal 21 nucleotides of yeast 17S ribosomal RNA. Nucleic Acids Res (1977) 1.41
Nucleotide sequence of gene VII and of a hypothetical gene (IX) in bacteriophage M13. Nucleic Acids Res (1978) 1.40
Sequence of the promoter-operator proximal region of the major leftward RNA of bacteriophage lambda. Nucleic Acids Res (1975) 1.40
Recognition sequence of restriction endonuclease KpnI from Klebsiella pneumoniae. Nucleic Acids Res (1978) 1.38
Adenovirus type 2 late mRNA's: structural evidence for 3'-coterminal species. J Virol (1978) 1.37
Transcription in vitro of bacteriophage lambda 4S RNA: studies on termination and rho protein. Nucleic Acids Res (1977) 1.33
Accurate processing of human pre-rRNA in vitro. Mol Cell Biol (1989) 1.33
Nucleotide sequences of human globin messenger RNA. Proc Natl Acad Sci U S A (1974) 1.26
The length of the terminal repetition in adenovirus-2 DNA. Proc Natl Acad Sci U S A (1974) 1.25
Comparison of nucleotide sequences of large T1 ribonuclease fragments of 18S ribosomal RNA of rat and chicken. Nucleic Acids Res (1979) 1.25
Nucleotide sequences of two fragments from the coat-protein cistron of bacteriophage R17 ribonucleic acid. Biochem J (1972) 1.23
Domains on the hepatitis C virus internal ribosome entry site for 40s subunit binding. RNA (2002) 1.22
Effect of viral RNase H on the avian sarcoma viral genome during early transcription in vitro. J Virol (1979) 1.16
Application of fingerprinting techniques to iodinated nucleic acids. Proc Natl Acad Sci U S A (1973) 1.16
Sequence analysis of the 3' non-coding region of mouse immunoglobulin light chain messenger RNA. Nucleic Acids Res (1977) 1.14
Sequence determination of the 3' terminal T1 oligonucleotide of 18S ribosomal RNA. Nucleic Acids Res (1976) 1.12
Nucleotide sequences of the 5' termini of phi X174 mRNAs synthesized in vitro. Nucleic Acids Res (1974) 1.12
Expression of bacteriophage M13 DNA in vivo. Localization of the transcription initiation and termination signal of the mRNA coding for the major capsid protein. Nucleic Acids Res (1978) 1.11
Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein. Proc Natl Acad Sci U S A (1996) 1.10
A site-specific single-strand endonuclease from the eukaryote Chlamydomonas. Proc Natl Acad Sci U S A (1977) 1.10
The nucleotide sequence surrounding the origin of DNA replication of Col E1. Nucleic Acids Res (1977) 1.10
Termination of transcription by bacteriophage T3 RNA polymerase: homogeneous 3'-terminal oligonucleotide sequence of in vitro T3 RNA polymerase transcripts. Proc Natl Acad Sci U S A (1979) 1.10
Enzymatic synthesis of oligonucleotides of defined sequence: synthesis of a segment of yeast iso-1-cytochrome c gene. Proc Natl Acad Sci U S A (1977) 1.09
Determination of genes, restriction sites, and DNA sequences surrounding the 6S RNA template of bacteriophage lambda. Proc Natl Acad Sci U S A (1975) 1.09
Influence of nucleotide sequence adjacent to duplex DNA termini on 3' terminal labeling by terminal transferase. Nucleic Acids Res (1979) 1.08
The nucleotide sequences of some large ribonuclease T 1 products from bacteriophage R17 ribonucleic acid. Biochem J (1971) 1.07
Structural analyses of E. coli 5S RNA fragments, their associates and complexes with proteins L18 and L25. Nucleic Acids Res (1982) 1.06
Pseudouridylation of yeast ribosomal precursor RNA. Nucleic Acids Res (1979) 1.06
Potato spindle tuber and citrus exocortis viroids undergo no major sequence changes during replication in two different hosts. Proc Natl Acad Sci U S A (1978) 1.06
Sequences spanning the EcoRI substrate site. Nucleic Acids Res (1975) 1.04
A new method for 3'-labelling of polyribonucleotides by phosphorylation with RNA ligase and its application to the 3'-modification for joining reactions. Nucleic Acids Res (1979) 1.04
The preparative synthesis of oligodeoxyribonucleotides using RNA ligase. Nucleic Acids Res (1982) 0.99
The repeating nucleotide sequence in the repetitive mitochondrial DNA from a "low-density" petite mutant of yeast. Nucleic Acids Res (1977) 0.98
Pausing of RNA polymerase molecules during in vivo transcription of the SV40 leader region. EMBO J (1983) 0.95
Sequence analysis and in vitro maturation of five precursor 5S RNAs from Bacillus Q. Nucleic Acids Res (1980) 0.93
Nucleotide sequences in bacteriophage ribonucleic acid. The eighth hopkins memorial lecture. Biochem J (1971) 0.93
Processing of eukaryotic tRNA precursors: secondary structure of the precursor specific sequences affects the rate but not the accuracy of processing reactions. Nucleic Acids Res (1982) 0.92
Sequence analysis of the nicks and termini of bacteriophage T5 DNA. J Virol (1977) 0.92
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Nucleotide sequence of bacteriophage phi X174 DNA. Nature (1977) 95.69
A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. J Mol Biol (1975) 90.35
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. J Mol Biol (1980) 61.16
Nucleotide and amino acid sequences of gene G of omegaX174. J Mol Biol (1976) 57.73
Sequence and organization of the human mitochondrial genome. Nature (1981) 57.39
The use of thin acrylamide gels for DNA sequencing. FEBS Lett (1978) 40.52
3' non-coding region sequences in eukaryotic messenger RNA. Nature (1976) 39.12
A two-dimensional fractionation procedure for radioactive nucleotides. J Mol Biol (1965) 20.83
Nucleotide sequence of bacteriophage lambda DNA. J Mol Biol (1982) 19.80
The nucleotide sequence of bacteriophage phiX174. J Mol Biol (1978) 13.55
The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype). Cell (1982) 12.44
The availability of the acetyl derivatives of lysine for growth. Biochem J (1943) 11.78
Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome. J Mol Biol (1982) 11.71
Rescue of influenza A virus from recombinant DNA. J Virol (1999) 11.54
A possible precursor of immunoglobulin light chains. Nat New Biol (1972) 11.03
The free amino groups of haemoglobins. Biochem J (1948) 10.93
New rapid gel sequencing method for RNA. Nature (1977) 9.56
Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA. Proc Natl Acad Sci U S A (1973) 7.11
Sequence of chicken ovalbumin mRNA. Nature (1978) 6.73
The sequence of 5 s ribosomal ribonucleic acid. J Mol Biol (1968) 6.47
Determination of nucleotide sequences in DNA. Science (1981) 6.02
The nucleotide sequence of oocyte 5S DNA in Xenopus laevis. II. The GC-rich region. Cell (1978) 5.87
Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype. Nature (1981) 4.86
Rapid gel sequencing of RNA by primed synthesis with reverse transcriptase. J Mol Biol (1977) 4.72
Sequence at the 3' end of globin mRNA shows homology with immunoglobulin light chain mRNA. Nature (1974) 4.24
The gene structure of human anti-haemophilic factor IX. EMBO J (1984) 4.09
The sequence of the nucleoprotein gene of human influenza A virus, strain A/NT/60/68. Nucleic Acids Res (1982) 3.99
Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells. Cell (1984) 3.97
Different pattern of codon recognition by mammalian mitochondrial tRNAs. Proc Natl Acad Sci U S A (1980) 3.74
The influenza virus panhandle is involved in the initiation of transcription. J Virol (1994) 3.56
Structure of the neuraminidase gene in human influenza virus A/PR/8/34. Nature (1981) 3.56
The metabolism of lysine. Biochem J (1944) 3.48
The antigenicity and evolution of influenza H1 haemagglutinin, from 1950-1957 and 1977-1983: two pathways from one gene. Virology (1986) 3.34
Nucleotide sequence homology at 12 intron--exon junctions in the chick ovalbumin gene. Nature (1978) 3.30
Nucleotide sequence from the coat protein cistron of R17 bacteriophage RNA. Nature (1969) 3.23
Nucleotide sequences from the low molecular weight ribosomal RNA of Escherichia coli. J Mol Biol (1967) 3.06
A new method for reconstituting influenza polymerase and RNA in vitro: a study of the promoter elements for cRNA and vRNA synthesis in vitro and viral rescue in vivo. Virology (1992) 2.85
AUG is the only recognisable signal sequence in the 5' non-coding regions of eukaryotic mRNA. Nature (1978) 2.76
Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance. Biochemistry (1981) 2.67
Use of polynucleotide kinase in fingerprinting non-radioactive nucleic acids. J Mol Biol (1969) 2.66
Gene deletions in patients with haemophilia B and anti-factor IX antibodies. Nature (1983) 2.59
Characterization of the RNA-fork model of virion RNA in the initiation of transcription in influenza A virus. J Virol (1995) 2.52
Molecular cloning of the gene for human anti-haemophilic factor IX. Nature (1982) 2.50
Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence. Nature (1987) 2.44
Antigenicity and evolution amongst recent influenza viruses of H1N1 subtype. Nucleic Acids Res (1983) 2.41
The use of synthetic oligodeoxynucleotide primers in cloning and sequencing segment of 8 influenza virus (A/PR/8/34). Nucleic Acids Res (1981) 2.40
Nucleotide sequence of 5S-ribosomal RNA from Escherichia coli. Nature (1967) 2.30
The 3' terminal sequence of chicken ovalbumin messenger RNA and its comparison with other messenger RNA molecules. J Mol Biol (1976) 2.29
Sequence analysis of immunoglobulin light chain messenger RNA. Nature (1974) 2.22
Photochemical cross-linking of influenza A polymerase to its virion RNA promoter defines a polymerase binding site at residues 9 to 12 of the promoter. J Gen Virol (1993) 2.17
The sequence of phenylalanine tRNA from E. coli. FEBS Lett (1969) 2.14
DNA sequencing with chain-terminating inhibitors. 1977. Biotechnology (1992) 2.13
A new method for the size estimation of the RNA genome segments of influenza virus. Nucleic Acids Res (1979) 2.12
Characterisation and use of an intragenic polymorphic marker for detection of carriers of haemophilia B (factor IX deficiency). Lancet (1984) 2.08
Sequence of 6S RNA of E. coli. Nat New Biol (1971) 2.06
Orthomyxovirus replication, transcription, and polyadenylation. Curr Top Microbiol Immunol (2004) 2.04
Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template. J Virol (1999) 2.01
Carrier detection in haemophilia B using two further intragenic restriction fragment length polymorphisms. Nucleic Acids Res (1984) 2.00
The influenza virus haemagglutinin gene: cloning and characterisation of a double-stranded DNA copy. Nucleic Acids Res (1979) 1.98
The nitrogen of the potato. Biochem J (1942) 1.94
The complete sequence of RNA segment 2 of influenza A/NT/60/68 P1 protein. Nucleic Acids Res (1982) 1.92
The structure of a Ca(2+)-binding epidermal growth factor-like domain: its role in protein-protein interactions. Cell (1995) 1.84
Defective propeptide processing of blood clotting factor IX caused by mutation of arginine to glutamine at position -4. Cell (1986) 1.82
An improved direct RNA sequence method; its application to Vicia faba 5.8S ribosomal RNA. Nucleic Acids Res (1980) 1.80
Sequence analysis of specific areas of the 16S and 23S ribosomal RNAs. Nature (1968) 1.78
Completion of the detailed restriction map of the E. coli genome by the isolation of overlapping cosmid clones. Nucleic Acids Res (1989) 1.71
Sequence of three introns in the chick ovalbumin gene. Nature (1979) 1.69
Polyadenylation of influenza virus mRNA transcribed in vitro from model virion RNA templates: requirement for 5' conserved sequences. J Virol (1998) 1.68
Key residues involved in calcium-binding motifs in EGF-like domains. Nature (1991) 1.68
Disruption of a C/EBP binding site in the factor IX promoter is associated with haemophilia B. Nature (1990) 1.68
A pseudogene structure in 5S DNA of Xenopus laevis. Cell (1977) 1.67
Attenuation of influenza A virus mRNA levels by promoter mutations. J Virol (1998) 1.63
Randomly picked cosmid clones overlap the pyrB and oriC gap in the physical map of the E. coli chromosome. Nucleic Acids Res (1988) 1.62
A hairpin loop at the 5' end of influenza A virus virion RNA is required for synthesis of poly(A)+ mRNA in vitro. J Virol (1999) 1.58
Nucleotides 9 to 11 of the influenza A virion RNA promoter are crucial for activity in vitro. J Gen Virol (1992) 1.57
The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX. EMBO J (1988) 1.54
Haemophilia B: database of point mutations and short additions and deletions--eighth edition. Nucleic Acids Res (1998) 1.54
Lysine deficiency in young rats. Biochem J (1943) 1.52
The RNA polymerase of influenza virus, bound to the 5' end of virion RNA, acts in cis to polyadenylate mRNA. J Virol (1998) 1.52
RNA-binding properties of influenza A virus matrix protein M1. Nucleic Acids Res (1989) 1.51
Translation of messenger RNA for immunoglobulin light chains in a cell-free system from Krebs II ascites cells. FEBS Lett (1972) 1.49
Purification and sequence of messenger RNA for immunoglobulin light chains. Nat New Biol (1973) 1.46
Haemophilia B (sixth edition): a database of point mutations and short additions and deletions. Nucleic Acids Res (1996) 1.44
3'End labelling of RNA with 32P suitable for rapid gel sequencing. Nucleic Acids Res (1978) 1.44
Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin. EMBO J (1986) 1.40
Mutational analysis of the RNA-fork model of the influenza A virus vRNA promoter in vivo. J Gen Virol (1997) 1.37
Studies on polysome-membrane interactions in mouse myeloma cells. Eur J Biochem (1974) 1.36
Multi-allelic RFLP for M27 beta, an anonymous single copy genomic clone at Xp11.3-Xcen [HGM9 provisional no. DXS255]. Nucleic Acids Res (1987) 1.36
Mutagenic analysis of the 5' arm of the influenza A virus virion RNA promoter defines the sequence requirements for endonuclease activity. J Virol (2001) 1.35
In vitro transcription and polymerase binding studies of the termini of influenza A virus cRNA: evidence for a cRNA panhandle. J Gen Virol (1995) 1.35
Haemophilia B caused by a point mutation in a donor splice junction of the human factor IX gene. Nature (1985) 1.34
The nucleotide sequence of a small (3S) seryl-tRNA (anticodon GCU) from beef heart mitochondria. Nucleic Acids Res (1980) 1.33
Determination of a nucleotide sequence in bacteriophage f1 DNA by primed synthesis with DNA polymerase. J Mol Biol (1974) 1.32
Sequence studies of the 5 S DNA of Xenopus laevis. J Mol Biol (1974) 1.31
Is there a correction mechanism in the 5S multigene system? Nature (1978) 1.30