Published in Cold Spring Harb Symp Quant Biol on January 01, 1969
The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. Proc Natl Acad Sci U S A (1974) 62.91
Bacterial ribosome. Bacteriol Rev (1970) 2.88
Identical 3'-terminal octanucleotide sequence in 18S ribosomal ribonucleic acid from different eukaryotes. A proposed role for this sequence in the recognition of terminator codons. Biochem J (1974) 2.52
Crystal structure of a translation termination complex formed with release factor RF2. Proc Natl Acad Sci U S A (2008) 2.33
Genetic screen for cloned release factor genes. J Bacteriol (1984) 2.09
Identification of the prfC gene, which encodes peptide-chain-release factor 3 of Escherichia coli. Proc Natl Acad Sci U S A (1994) 2.00
Peptide chain termination with mammalian release factor. Proc Natl Acad Sci U S A (1970) 1.82
Mammalian peptide chain termination. II. Codon specificity and GTPase activity of release factor. Proc Natl Acad Sci U S A (1971) 1.79
Hydrolysis of fMet-tRNA by peptidyl transferase. Proc Natl Acad Sci U S A (1971) 1.67
Conserved motifs in prokaryotic and eukaryotic polypeptide release factors: tRNA-protein mimicry hypothesis. Proc Natl Acad Sci U S A (1996) 1.64
Role of 5S RNA in the functions of 50S ribosomal subunits. Proc Natl Acad Sci U S A (1971) 1.62
Seryl-tRNA in mammalian tissues: chromatographic differences in brain and liver and a specific response to the codon, UGA. Proc Natl Acad Sci U S A (1970) 1.41
Translation of the genome of a ribonucleic acid bacteriophage. Bacteriol Rev (1972) 1.40
Is UAA or UGA part of the recognition signal for ribosomal initiation? Nucleic Acids Res (1979) 1.31
Recognition of the amber UAG stop codon by release factor RF1. EMBO J (2010) 1.23
Release factor RF-3 GTPase activity acts in disassembly of the ribosome termination complex. RNA (1998) 1.19
Reinitiation of translation from the triplet next to the amber termination codon in the absence of ribosome-releasing factor. Proc Natl Acad Sci U S A (1981) 1.18
Escherichia coli release factor 3: resolving the paradox of a typical G protein structure and atypical function with guanine nucleotides. RNA (1998) 1.10
The ribosomal binding and peptidyl-tRNA hydrolysis functions of Escherichia coli release factor 2 are linked through residue 246. RNA (2000) 1.02
A primary role for release factor 3 in quality control during translation elongation in Escherichia coli. Cell (2011) 1.01
DNA-directed synthesis in vitro of beta-galactosidase: requirement for a ribosome release factor. Proc Natl Acad Sci U S A (1977) 0.97
Comparative characterization of release factor RF-3 genes of Escherichia coli, Salmonella typhimurium, and Dichelobacter nodosus. J Bacteriol (1995) 0.93
Crystal structure of the 70S ribosome bound with the Q253P mutant form of release factor RF2. Structure (2013) 0.87
The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G). Nucleic Acids Res (2008) 0.87
Distinct roles for release factor 1 and release factor 2 in translational quality control. J Biol Chem (2014) 0.83
Overproduction of release factor reduces spontaneous frameshifting and frameshift suppression by mutant elongation factor Tu. J Bacteriol (1990) 0.81
Interactions of release factor RF3 with the translation machinery. Mol Genet Genomics (2015) 0.81
Sequential translation of trinucleotide codons for peptide bond formation, translocation, and termination. Proc Natl Acad Sci U S A (1970) 0.75
Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell (1987) 20.47
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature (1988) 20.36
High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell (1980) 8.30
Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules. Mol Cell Biol (1982) 7.49
High frequency targeting of genes to specific sites in the mammalian genome. Cell (1986) 6.91
N-formylmethionyl-sRNA as the initiator of protein synthesis. Proc Natl Acad Sci U S A (1966) 5.50
Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature (1991) 4.60
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. Cell (1983) 4.53
Retinopathy induced in mice by targeted disruption of the rhodopsin gene. Nat Genet (1997) 4.50
Suppression in vitro: Identification of a Serine-sRNA as a "Nonsense" Suppressor. Science (1965) 4.34
Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol Cell Biol (1992) 4.19
Initiation of E. coli proteins. Proc Natl Acad Sci U S A (1966) 4.07
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature (1990) 3.92
Targeting genes for self-excision in the germ line. Genes Dev (1999) 3.59
The new mouse genetics: altering the genome by gene targeting. Trends Genet (1989) 3.53
Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene. Nature (1986) 3.30
Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian cell nuclei. Mol Cell Biol (1985) 3.00
Peptide synthesis by prokaryotic-eukaryotic hybrid ribosomes. J Biol Chem (1972) 2.84
Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6. Nature (1992) 2.82
Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids. Proc Natl Acad Sci U S A (2000) 2.71
A mouse model for the delta F508 allele of cystic fibrosis. J Clin Invest (1995) 2.48
Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Lab Invest (1996) 2.47
Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. Nature (1995) 2.40
Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development (1993) 2.39
Maintenance of functional equivalence during paralogous Hox gene evolution. Nature (2000) 2.24
Altered enzymes in drug-resistant variants of mammalian tissue culture cells. Proc Natl Acad Sci U S A (1973) 2.24
Fgf8 is required for outgrowth and patterning of the limbs. Nat Genet (2000) 2.18
Cell-free protein synthesis programmed with R17 RNA: identification of two phage proteins. J Mol Biol (1966) 2.18
Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny. Dev Biol (1997) 2.16
High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Mol Cell Biol (1992) 2.14
Polypeptide chain termination in vitro: isolation of a release factor. Proc Natl Acad Sci U S A (1967) 2.08
The role of Hoxa-3 in mouse thymus and thyroid development. Development (1995) 1.93
Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro. Cell (1975) 1.87
Hoxc13 mutant mice lack external hair. Genes Dev (1998) 1.84
Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Genes Dev (1995) 1.80
Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy. Proc Natl Acad Sci U S A (1999) 1.77
Establishment of mammalian cell lines containing multiple nonsense mutations and functional suppressor tRNA genes. Cell (1982) 1.76
Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Development (1994) 1.73
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions. Nature (1994) 1.66
Selective degradation of abnormal proteins in mammalian tissue culture cells. Proc Natl Acad Sci U S A (1974) 1.66
Location of crossovers during gene targeting with insertion and replacement vectors. Mol Cell Biol (1993) 1.64
A mutational analysis of the 5' HoxD genes: dissection of genetic interactions during limb development in the mouse. Development (1996) 1.60
The isolation of a suppressible nonsense mutant in mammalian cells. Cell (1977) 1.53
Mice homozygous for a targeted disruption of Hoxd-3 (Hox-4.1) exhibit anterior transformations of the first and second cervical vertebrae, the atlas and the axis. Development (1993) 1.49
The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. J Clin Invest (1997) 1.48
Targeted mutations in hoxa-9 and hoxb-9 reveal synergistic interactions. Dev Biol (1997) 1.47
Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs. Development (2001) 1.46
Targeted disruptions of the murine Hoxa-4 and Hoxa-6 genes result in homeotic transformations of components of the vertebral column. Mech Dev (1994) 1.45
Analysis of homologous recombination in cultured mammalian cells. Cold Spring Harb Symp Quant Biol (1984) 1.43
Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. Genes Dev (1994) 1.41
Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Dev Biol (1998) 1.41
Efficient correction of mismatched bases in plasmid heteroduplexes injected into cultured mammalian cell nuclei. Mol Cell Biol (1985) 1.37
Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination. Proc Natl Acad Sci U S A (1990) 1.36
Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain. Development (1993) 1.34
Swaying is a mutant allele of the proto-oncogene Wnt-1. Cell (1991) 1.33
Cleft palate in mice with a targeted mutation in the gamma-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67. Proc Natl Acad Sci U S A (1997) 1.31
Normal limb development in conditional mutants of Fgf4. Development (2000) 1.31
Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Dev Biol (1997) 1.28
Roles of Hoxa1 and Hoxa2 in patterning the early hindbrain of the mouse. Development (2000) 1.25
Immunological characterization of hypoxanthine-guanine phosphoribosyl transferase mutants of mouse L cells: evidence for mutations at different loci in the HGPRT gene. J Cell Physiol (1975) 1.24
Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve. Development (1996) 1.23
Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development (1999) 1.23
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations. Dev Biol (1996) 1.22
Compensatory defects associated with mutations in Hoxa1 restore normal palatogenesis to Hoxa2 mutants. Development (1999) 1.16
Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the v-abl oncogene. Proc Natl Acad Sci U S A (1986) 1.15
Expression of a microinjected porcine class I major histocompatibility complex gene in transgenic mice. Science (1985) 1.12
Analysis of homologous recombination in cultured mammalian cells in transient expression and stable transformation assays. Somat Cell Mol Genet (1986) 1.11
Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells. EMBO J (1984) 1.11
Targeted gene replacement. Sci Am (1994) 1.10
Targeted disruption of Hoxd-10 affects mouse hindlimb development. Development (1997) 1.08
Computer analysis of radionuclide esophageal transit studies. J Nucl Med (1984) 1.08
Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase. Mol Cell Biol (1987) 1.07
The mouse Hoxc11 gene: genomic structure and expression pattern. Mech Dev (1998) 1.05
Polarity in vitro. J Mol Biol (1967) 1.05
Polypetide chain termination. Purification of the release factors, R1 and R2, from Escherichia coli. J Biol Chem (1971) 1.05
Detection of targeted GFP-Hox gene fusions during mouse embryogenesis. Proc Natl Acad Sci U S A (1998) 1.02
Analysis of Hoxa7/Hoxb7 mutants suggests periodicity in the generation of the different sets of vertebrae. Mech Dev (1998) 0.99
Hoxb2 and hoxb4 act together to specify ventral body wall formation. Dev Biol (2001) 0.98
Release factors mediating termination of complete proteins. Nature (1970) 0.98
Targeted disruption of the Hoxb-2 locus in mice interferes with expression of Hoxb-1 and Hoxb-4. Development (1996) 0.98
Role of inflammation in the lung disease of systemic sclerosis: comparison with idiopathic pulmonary fibrosis. J Lab Clin Med (1986) 0.94
Purification and characterization of mouse hypoxanthine-guanine phosphoribosyltransferase. J Biol Chem (1975) 0.93
Mouse genetics. YACs to the rescue. Nature (1993) 0.92
Effect of cell cycle position on transformation by microinjection. Somat Cell Mol Genet (1985) 0.88
Hertz-level measurement of the optical clock frequency in a single 88Sr+ ion. Science (2004) 0.88
Hoxb1 controls effectors of sonic hedgehog and Mash1 signaling pathways. Development (2000) 0.88
Protein synthesis directed by DNA phage messengers. Cold Spring Harb Symp Quant Biol (1966) 0.86
Sequence-independent assembly of spermatid mRNAs into messenger ribonucleoprotein particles. Mol Cell Biol (1999) 0.86
Scintigraphy versus pH probe for quantification of pediatric gastroesophageal reflux: a study using concurrent multiplexed data and acid feedings. J Nucl Med (1993) 0.86
The scope of false-positive iodine-131 images for thyroid carcinoma. Clin Nucl Med (1989) 0.85
The role of the lateral malleolus as a stabilizing factor of the ankle joint: preliminary report. Foot Ankle (1981) 0.85
Correlates of life satisfaction among military wives. J Psychol (1989) 0.84
Multidimensional self-perception: linkages to parental nurturance. J Genet Psychol (1993) 0.84
Fractionation of a suppressor sRNA. J Mol Biol (1966) 0.84
Targeting of genes to specific sites in the mammalian genome. Cold Spring Harb Symp Quant Biol (1986) 0.83
The relationship of temperament to adjustment in British infant schools. J Soc Psychol (1988) 0.81
Recombinant DNA technique and sickle cell anemia research. Science (1997) 0.80
Hair defects in Hoxc13 mutant mice. J Investig Dermatol Symp Proc (1999) 0.80
SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas. Oncogene (2012) 0.79