Published in J Bacteriol on February 01, 1967
Extrachromosomal elements as possible agents of adaptation and development. Bacteriol Rev (1976) 5.62
Genetic analysis of tox+ and tox- bacteriophages of Corynebacterium diphtheriae. J Virol (1969) 2.71
Synthesis of diphtheria tox-gene products in Escherichia coli extracts. Proc Natl Acad Sci U S A (1974) 2.62
Corynebacterium diphtheriae and its relatives. Bacteriol Rev (1970) 2.54
Evidence that the regulation of diphtheria toxin production is directed at the level of transcription. J Bacteriol (1978) 2.34
Characterization and genetic mapping of nontoxinogenic (tox) mutants of corynebacteriophage beta. J Virol (1976) 2.33
Regulation of toxinogenesis in Corynebacterium diphtheriae. I. Mutations in bacteriophage beta that alter the effects of iron on toxin production. J Virol (1981) 1.65
Comparative studies with tox plus and tox minus corynebacteriophages. J Virol (1970) 1.55
Induction of lysogenic bacteriophage and phage-associated toxin from group a streptococci during coculture with human pharyngeal cells. Infect Immun (2001) 1.46
The in vitro interaction of Streptococcus pyogenes with human pharyngeal cells induces a phage-encoded extracellular DNase. Infect Immun (2002) 1.26
Evidence for direct regulation of diphtheria toxin gene transcription by an Fe2+-dependent DNA-binding repressor, DtoxR, in Corynebacterium diphtheriae. Infect Immun (1989) 1.22
Genetic basis of toxin production and pathogenesis in Vibrio cholerae: evidence against phage conversion. Infect Immun (1975) 1.12
Park-Williams number 8 strain of Corynebacterium diphtheriae. J Bacteriol (1971) 1.04
Distribution of neuraminidase and n-acetylneuraminate lyase activities among corynebacteria, mycobacteria, and nocardias. J Bacteriol (1972) 0.98
Genome organization and pathogenicity of Corynebacterium diphtheriae C7(-) and PW8 strains. Infect Immun (2010) 0.93
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J (1956) 124.75
Agar layer method for production of high titer phage stocks. Proc Soc Exp Biol Med (1951) 12.04
Studies on the virulence of bacteriophage-infected strains of Corynebacterium diphtheriae. J Bacteriol (1951) 10.22
Phage-host relationships in nontoxigenic and toxigenic diphtheria bacilli. J Bacteriol (1954) 4.29
An Analysis of the Action of Proflavine on Bacteriophage Growth. J Bacteriol (1948) 3.43
The production of phage-related materials when bacteriophage development in interrupted by proflavine. Virology (1955) 3.20
Toxinogeny in Corynebacterium diphtheriae. J Bacteriol (1961) 2.12
The purification of diphtheria toxin and the isolation of crystalline toxin-protein. Br J Exp Pathol (1958) 1.89
Phage-directed synthesis of diphtherial toxin in non-toxinogenic Corynebacterium diphtheriae. Nature (1966) 1.45
Phage-host relationships in certain strains of Corynebacterium diphtheriae. Virology (1966) 1.37
Bacteriophages for C. diphtheriae. Can J Public Health (1950) 1.35
Purification of diphtheria toxin. I. Application of zone electrophoresis in a starch-supporting medium as a means of fractionation of toxin. Jpn J Microbiol (1957) 1.23
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol (2000) 9.85
A family of cAMP-binding proteins that directly activate Rap1. Science (1998) 6.12
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell (2000) 5.92
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature (2001) 4.83
Persisting bacteriophage infections, lysogeny, and phage conversions. Annu Rev Microbiol (1974) 4.01
The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer (1999) 3.47
Mycobacterium. Bacteriol Rev (1977) 3.20
Specificity of DNase I. Estimation of nucleosides present at the 5'-phosphate terminus of a limit digest of DNA by DNase I. J Biochem (1966) 2.96
Phospholipase C assay using p-nitrophenylphosphoryl-choline together with sorbitol and its application to studying the metal and detergent requirement of the enzyme. Anal Biochem (1976) 2.87
Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev (1998) 2.82
Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia (2003) 2.80
Genetic analysis of tox+ and tox- bacteriophages of Corynebacterium diphtheriae. J Virol (1969) 2.71
Human immunodeficiency virus vpr gene encodes a virion-associated protein. AIDS Res Hum Retroviruses (1990) 2.67
Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein. J Virol (1990) 2.60
Corynebacterium diphtheriae and its relatives. Bacteriol Rev (1970) 2.54
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. Proc Natl Acad Sci U S A (1998) 2.47
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol (1996) 2.44
Preoperative identification of meningiomas that are highly likely to recur. J Neurosurg (1999) 2.38
Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin. J Cell Biol (1997) 2.25
Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i) Nature (1999) 2.23
Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome. Proc Natl Acad Sci U S A (1988) 2.20
The long-term effects of polymethylmethacrylate contact lens wear on the corneal endothelium. Ophthalmology (1994) 2.05
Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res (1993) 1.95
Corneal endothelial changes in type I and type II diabetes mellitus. Am J Ophthalmol (1984) 1.94
Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo. J Biol Chem (1997) 1.91
Abnormal plasminogen. A hereditary molecular abnormality found in a patient with recurrent thrombosis. J Clin Invest (1978) 1.79
Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J (2001) 1.74
Isolation and purification of two antigenically active, "complimentary" polypeptide fragments of tetanus neurotoxin. Infect Immun (1975) 1.74
Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man. Diabetologia (1994) 1.73
Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex. J Biol Chem (1998) 1.72
Recent dioxin contamination from Agent Orange in residents of a southern Vietnam city. J Occup Environ Med (2001) 1.68
Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection. Am J Pathol (1999) 1.66
Nonrandom distribution of gp120 N-linked glycosylation sites important for infectivity of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1992) 1.61
Phospholipase D activity of Corynebacterium pseudotuberculosis (Corynebacterium ovis) and Corynebacterium ulcerans, a distinctive marker within the genus Corynebacterium. J Clin Microbiol (1981) 1.59
Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone. Diabetes Care (2001) 1.56
Gene expression profiling of exercise-induced cardiac hypertrophy in rats. Acta Physiol Scand (2005) 1.55
Bromocriptine: a novel approach to the treatment of type 2 diabetes. Diabetes Care (2000) 1.55
Comparative studies with tox plus and tox minus corynebacteriophages. J Virol (1970) 1.55
Non-invasive assessment of cardiac output during exercise in healthy young humans: comparison between Modelflow method and Doppler echocardiography method. Acta Physiol Scand (2003) 1.54
In vivo evaluation of NM441, a new thiazeto-quinoline derivative. Antimicrob Agents Chemother (1991) 1.49
Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type II diabetic patients. Diabetologia (2001) 1.48
Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett (1994) 1.47
Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance. J Gastroenterol (2000) 1.47
Heritable artificial sex chromosomes in the medaka, Oryzias latipes. Heredity (Edinb) (2009) 1.46
Cytochemical reactions of human leprosy bacilli and mycobacteria: ultrastructural implications. J Bacteriol (1973) 1.46
Swine influenza virus strains recognize sialylsugar chains containing the molecular species of sialic acid predominantly present in the swine tracheal epithelium. FEBS Lett (1997) 1.46
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway. Proc Natl Acad Sci U S A (1998) 1.46
Changes in the normal corneal endothelial cellular pattern as a function of age. Curr Eye Res (1985) 1.46
Phage-directed synthesis of diphtherial toxin in non-toxinogenic Corynebacterium diphtheriae. Nature (1966) 1.45
Lp(a) lipoprotein as a risk factor for coronary heart disease and cerebral infarction. Atherosclerosis (1986) 1.43
Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3. J Biol Chem (2000) 1.42
13-cis retinoic acid inhibits growth of adult T cell leukemia cells and causes apoptosis; possible new indication for retinoid therapy. Intern Med (1996) 1.41
CalDAG-GEFIII activation of Ras, R-ras, and Rap1. J Biol Chem (2000) 1.40
Increased expression of intercellular adhesion molecule-1 (ICAM-1) in diabetic rat glomeruli: glomerular hyperfiltration is a potential mechanism of ICAM-1 upregulation. Diabetes (1997) 1.40
An infectious DNA clone of HIV type 1 subtype C. AIDS Res Hum Retroviruses (1999) 1.40
A case of Hashimoto's thyroiditis with antibodies to thyroid hormone analogues. Clin Chim Acta (1992) 1.39
A locus for female discrimination behavior causing sexual isolation in Drosophila. Proc Natl Acad Sci U S A (2001) 1.39
Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein rho. J Cell Sci (1995) 1.38
Activation of R-Ras by Ras-guanine nucleotide-releasing factor. J Biol Chem (1997) 1.36
Amino acids of the cell wall of Nocardia rubra. J Bacteriol (1971) 1.35
Equi factors in the identification of Corynebacterium equi Magnusson. J Clin Microbiol (1982) 1.35
Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells. Mol Cell Biol (1993) 1.34
Ultrastructure of superficial mycosidic integuments of Mycobacterium sp. J Bacteriol (1976) 1.34
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho. Proc Natl Acad Sci U S A (1997) 1.33
Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade. Mol Cell Biol (2000) 1.32
The behavior of alpha2-plasmin inhibitor in fibrinolytic states. J Clin Invest (1977) 1.31
Comparison of the corneal endothelium in an American and a Japanese population. Arch Ophthalmol (1985) 1.28
Aquaporin adipose, a putative glycerol channel in adipocytes. J Biol Chem (2000) 1.28
Effects of exercise training of 8 weeks and detraining on plasma levels of endothelium-derived factors, endothelin-1 and nitric oxide, in healthy young humans. Life Sci (2001) 1.27
Genetic characterization of JC virus Tokyo-1 strain, a variant oncogenic in rodents. Virus Res (1987) 1.27
Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells. Biochem Soc Trans (2005) 1.26
Neuraminidase of Corynebacterium diphtheriae. J Bacteriol (1967) 1.26
Temperature-sensitive mutants on nonlysogenizing corynebacteriophage hv : their isolation, characterization and relation to toxiongenesis. Biken J (1971) 1.26
In vitro antibacterial activity of a new quinolone, NM394. Antimicrob Agents Chemother (1991) 1.25
Response of the corneal endothelium to cataract surgery. Arch Ophthalmol (1986) 1.24
A new technique for laparoscopic cholecystectomy--retrograde laparoscopic cholecystectomy: an analysis of 81 cases. Endoscopy (1996) 1.24
Effects of intraocular irrigating solutions on the corneal endothelium after in vivo anterior chamber irrigation. Am J Ophthalmol (1985) 1.24
Primary structure of human poly(ADP-ribose) synthetase as deduced from cDNA sequence. J Biol Chem (1987) 1.23
Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in impaired glucose tolerance. Diabetologia (2003) 1.22
DNA isolated from Mycobacterium leprae: genome size, base ratio, and homology with other related bacteria as determined by optical DNA-DNA reassociation. J Bacteriol (1982) 1.22
Quantitative analysis of narrowings of intramyocardial small arteries in normal hearts, hypertensive hearts, and hearts with hypertrophic cardiomyopathy. Circulation (1987) 1.22
Prevalence of thyroid hormone autoantibodies in healthy subjects. Clin Endocrinol (Oxf) (1994) 1.21
A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo. J Biol Chem (2001) 1.20
Management of the pancreatic metastases from renal cell carcinoma: report of four resected cases. Hepatogastroenterology (1998) 1.20
Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling. J Biol Chem (2001) 1.19
[A case of colonic carcinoma associated with intestinal tuberculosis, and an analysis of 26 cases reported in Japan]. Gan No Rinsho (1987) 1.18
Primary action of Clostridium perfringens type A enterotoxin on HeLa and Vero cells in the absence of extracellular calcium: rapid and characteristic changes in membrane permeability. Biochem Biophys Res Commun (1986) 1.18
Gastric small-cell carcinoma in Japan: a case report and review of the literature. Am J Clin Oncol (1998) 1.18
Campylobacter jejuni. Lett Appl Microbiol (2005) 1.18
Angiolipoma of the colon with right lower quadrant abdominal pain. Dig Surg (1999) 1.18
Laparoscopic cholecystectomy from fundus downward. Surg Laparosc Endosc (1994) 1.17
Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504. J Biol Chem (1999) 1.16
Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes. EMBO J (1998) 1.16
Reconstitution and poly(ADP-ribosyl)ation of proteolytically fragmented poly(ADP-ribose) synthetase. J Biol Chem (1986) 1.16
Serial alterations in endothelial cell shape and pattern after intraocular surgery. Am J Ophthalmol (1984) 1.16
Antigenic substructure of tetanus neurotoxin. Biochem Biophys Res Commun (1977) 1.15
Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat. Am J Physiol Regul Integr Comp Physiol (2001) 1.14
Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2. J Biol Chem (1993) 1.13