PubRank

R G Roeder

Author PubWeight™ 870.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983 124.30
2 Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell 1979 19.98
3 Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997 16.79
4 Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell 1985 13.36
5 Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates. J Biol Chem 1979 11.68
6 Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes. Cell 1980 10.87
7 Multiple factors required for accurate initiation of transcription by purified RNA polymerase II. J Biol Chem 1980 10.78
8 Multiple factors are required for the accurate transcription of purified genes by RNA polymerase III. J Biol Chem 1980 10.63
9 Eukaryotic gene transcription with purified components. Methods Enzymol 1983 9.71
10 Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free system. Cell 1980 8.02
11 Definition of a novel promoter for the major adenovirus-associated virus mRNA. Cell 1980 7.42
12 Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters. Mol Cell Biol 1981 7.12
13 Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Mol Cell Biol 1983 7.01
14 Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms. Nature 1969 6.98
15 Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. Proc Natl Acad Sci U S A 1985 6.94
16 The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev 1990 6.88
17 Transcription of class III genes: formation of preinitiation complexes. Science 1983 6.79
18 Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res 1981 6.63
19 DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. Proc Natl Acad Sci U S A 1982 6.57
20 Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science 1970 6.39
21 Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol Cell Biol 1988 5.60
22 Biochemistry and structural biology of transcription factor IID (TFIID). Annu Rev Biochem 1996 5.19
23 Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell 1987 5.04
24 Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature 1995 4.93
25 Crystal structure of TFIID TATA-box binding protein. Nature 1992 4.85
26 A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc Natl Acad Sci U S A 1988 4.72
27 Specific nucleolar and nucleoplasmic RNA polymerases. Proc Natl Acad Sci U S A 1970 4.63
28 Synergistic activation of transcription by CBP and p53. Nature 1997 4.54
29 Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II. Cell 1987 4.37
30 Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro. Cell 1987 4.37
31 Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proc Natl Acad Sci U S A 1988 4.33
32 Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development. Cell 1984 4.32
33 Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell 1988 4.15
34 Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature 1991 4.09
35 Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site. J Biol Chem 1987 4.08
36 Inducible binding of a factor to the c-fos enhancer. Cell 1986 3.98
37 Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. J Biol Chem 1988 3.96
38 A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein. Nature 1988 3.95
39 Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. J Biol Chem 1985 3.89
40 Isolation and partial characterization of the multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in the mouse myeloma, MOPC 315. J Biol Chem 1974 3.84
41 Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes. Proc Natl Acad Sci U S A 1986 3.81
42 Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box. Nature 1989 3.74
43 Structure and function of the b/HLH/Z domain of USF. EMBO J 1994 3.70
44 Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc Natl Acad Sci U S A 1996 3.61
45 c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore. Mol Cell Biol 1987 3.52
46 Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science 1995 3.50
47 Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Res 1991 3.48
48 The structure of the human histone genes: clustered but not tandemly repeated. Cell 1981 3.47
49 Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell 1999 3.47
50 Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell 1994 3.43
51 Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). Nature 1990 3.42
52 Physical analysis of transcription preinitiation complex assembly on a class II gene promoter. Science 1988 3.40
53 Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. J Biol Chem 1987 3.38
54 Activation of class II gene transcription by regulatory factors is potentiated by a novel activity. Cell 1991 3.36
55 Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol Cell Biol 2001 3.31
56 Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus. Cell 1985 3.21
57 Family of proteins that interact with TFIID and regulate promoter activity. Cell 1991 3.20
58 Mechanism of action of a yeast activator: direct effect of GAL4 derivatives on mammalian TFIID-promoter interactions. Cell 1988 3.17
59 The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene. Cell 1981 3.15
60 Role of DNA-dependent RNA polymerase 3 in the transcription of the tRNA and 5S RNA genes. Proc Natl Acad Sci U S A 1974 3.14
61 Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. Trends Biochem Sci 2000 3.03
62 Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta. Nature 1995 2.96
63 Role of DNA-dependent RNA polymerases II and III in transcription of the adenovirus genome late in productive infection. Proc Natl Acad Sci U S A 1974 2.95
64 Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. J Biol Chem 1987 2.95
65 Formation of a rate-limiting intermediate in 5S RNA gene transcription. Cell 1985 2.94
66 Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature 1996 2.92
67 Direct interaction of human TFIID with the HIV-1 transactivator tat. Nature 1994 2.87
68 Activation of transcription factor IIIC by the adenovirus E1A protein. Cell 1988 2.86
69 HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. Genes Dev 1992 2.85
70 Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis. Isolation and partial characterization. J Biol Chem 1974 2.80
71 The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc Natl Acad Sci U S A 1998 2.76
72 Multiple factors involved in the transcription of class III genes in Xenopus laevis. J Biol Chem 1982 2.75
73 Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol Cell Biol 1995 2.74
74 A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. Mol Cell 1999 2.71
75 Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer. Proc Natl Acad Sci U S A 1988 2.70
76 Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Mol Cell Biol 1986 2.69
77 HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. Mol Cell 2000 2.68
78 Purification of the c-fos enhancer-binding protein. Mol Cell Biol 1987 2.64
79 The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions. Genes Dev 1988 2.60
80 Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature 1996 2.58
81 Association of a 5S gene transcription factor with 5S RNA and altered levels of the factor during cell differentiation. Cell 1980 2.58
82 Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III. EMBO J 1993 2.56
83 The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1. Nature 1993 2.50
84 Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes Dev 1988 2.47
85 Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Mol Cell Biol 1992 2.47
86 Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes Dev 1996 2.45
87 Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters. EMBO J 1993 2.45
88 A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors. Cell 1992 2.43
89 Transcripts of the adeno-associated virus genome: mapping of the major RNAs. J Virol 1980 2.42
90 A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID. J Biol Chem 1998 2.40
91 Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Mol Cell 2000 2.39
92 Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Mol Cell Biol 1984 2.38
93 Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes. Mol Cell Biol 1995 2.33
94 Low molecular weight viral RNAs transcribed by RNA polymerase III during adenovirus 2 infection. Cell 1976 2.33
95 Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science 1988 2.31
96 Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III. EMBO J 1999 2.28
97 Direct role for Myc in transcription initiation mediated by interactions with TFII-I. Nature 1993 2.28
98 Transcription of human histone genes in extracts from synchronized HeLa cells. Proc Natl Acad Sci U S A 1984 2.27
99 Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains. J Biol Chem 1987 2.27
100 The TRAP/SMCC/Mediator complex and thyroid hormone receptor function. Trends Endocrinol Metab 2001 2.26
101 Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression. Genes Dev 1993 2.26
102 Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300. Mol Cell 2000 2.25
103 Transcriptional regulation by the immediate early protein of pseudorabies virus during in vitro nucleosome assembly. Cell 1988 2.23
104 A histone octamer-like structure within TFIID. Nature 1996 2.21
105 The primary structure and expression of four cloned human histone genes. Nucleic Acids Res 1983 2.21
106 Energy requirement for specific transcription initiation by the human RNA polymerase II system. J Biol Chem 1984 2.20
107 Repression of HIV-1 transcription by a cellular protein. Science 1991 2.17
108 Interaction of TFIID in the minor groove of the TATA element. Cell 1991 2.17
109 Crystal structure of a human TATA box-binding protein/TATA element complex. Proc Natl Acad Sci U S A 1996 2.15
110 Analysis of the role of the transcription factor ATF in the assembly of a functional preinitiation complex. Cell 1988 2.13
111 Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro. Genes Dev 1992 2.12
112 Topology and reorganization of a human TFIID-promoter complex. Nature 1996 2.10
113 Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity. Nature 1993 2.10
114 The sarcomeric actin CArG-binding factor is indistinguishable from the c-fos serum response factor. Mol Cell Biol 1989 2.05
115 Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF. Mol Cell Biol 1991 2.04
116 Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation. EMBO J 1998 2.04
117 Ribosomal RNA synthesis in isolated nuclei. J Mol Biol 1972 2.03
118 The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription. EMBO J 1990 2.01
119 Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation. Genes Dev 1997 2.00
120 Physical properties and DNA-binding stoichiometry of a 5 S gene-specific transcription factor. J Biol Chem 1984 2.00
121 Transcription of cloned Xenopus 5S RNA genes by X. laevis RNA polymerase III in reconstituted systems. Proc Natl Acad Sci U S A 1979 2.00
122 An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly. EMBO J 1990 1.99
123 Spermiogenesis deficiency in mice lacking the Trf2 gene. Science 2001 1.99
124 Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains. Proc Natl Acad Sci U S A 1995 1.96
125 Arabidopsis thaliana contains two genes for TFIID. Nature 1990 1.92
126 The 5S gene internal control region is composed of three distinct sequence elements, organized as two functional domains with variable spacing. Cell 1987 1.92
127 Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID. Genes Dev 1990 1.90
128 An alternative pathway for transcription initiation involving TFII-I. Nature 1993 1.87
129 The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. J Biol Chem 1994 1.87
130 The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes. Nature 1996 1.84
131 Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro. Proc Natl Acad Sci U S A 1986 1.82
132 Expression and purification of general transcription factors by FLAG epitope-tagging and peptide elution. Pept Res 1993 1.80
133 Quantitation of RNA polymerase II and its transcription factors in an HeLa cell: little soluble holoenzyme but significant amounts of polymerases attached to the nuclear substructure. Mol Cell Biol 1999 1.79
134 TATA-binding protein-associated factor(s) in TFIID function through the initiator to direct basal transcription from a TATA-less class II promoter. EMBO J 1994 1.79
135 Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE. Nature 1991 1.79
136 Regulation of TFIIH ATPase and kinase activities by TFIIE during active initiation complex formation. Nature 1994 1.78
137 Thyroid hormone receptor-associated proteins and general positive cofactors mediate thyroid hormone receptor function in the absence of the TATA box-binding protein-associated factors of TFIID. Proc Natl Acad Sci U S A 1999 1.77
138 Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Proc Natl Acad Sci U S A 1993 1.76
139 Structural organization of yeast and mammalian mediator complexes. Proc Natl Acad Sci U S A 2000 1.76
140 Multiple sequence elements in the c-fos promoter mediate induction by cAMP. Genes Dev 1989 1.76
141 Purification and analysis of a factor which suppresses nick-induced transcription by RNA polymerase II and its identity with poly(ADP-ribose) polymerase. J Biol Chem 1983 1.74
142 Sequence of general transcription factor TFIIB and relationships to other initiation factors. Proc Natl Acad Sci U S A 1991 1.74
143 Stability of transcription complexes on class II genes. Mol Cell Biol 1989 1.73
144 A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription. EMBO J 1999 1.73
145 Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1. EMBO J 1997 1.72
146 Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter. Nature 1989 1.72
147 Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proc Natl Acad Sci U S A 1986 1.71
148 Purification of a yeast TATA box-binding protein that exhibits human transcription factor IID activity. Proc Natl Acad Sci U S A 1989 1.70
149 Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein. Mol Cell Biol 1996 1.70
150 Molecular cloning of Drosophila TFIID subunits. Nature 1994 1.69
151 Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation. Proc Natl Acad Sci U S A 1994 1.67
152 Transcription factor TFIID induces DNA bending upon binding to the TATA element. Proc Natl Acad Sci U S A 1992 1.67
153 Expression of the autonomous parvovirus H1 genome: evidence for a single transcriptional unit and multiple spliced polyadenylated transcripts. Cell 1979 1.66
154 The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs. Mol Cell 2000 1.65
155 Transcripts of the adenovirus-associated virus genome: multiple polyadenylated RNAs including a potential primary transcript. J Virol 1980 1.63
156 Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat. Mol Cell Biol 1989 1.63
157 Genomic organization and nucleotide sequence of two distinct histone gene clusters from Xenopus laevis. Identification of novel conserved upstream sequence elements. J Mol Biol 1985 1.63
158 Analysis of structure-function relationships of yeast TATA box binding factor TFIID. Cell 1990 1.63
159 Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro. Mol Cell Biol 1994 1.62
160 Conserved sequence motifs in the small subunit of human general transcription factor TFIIE. Nature 1991 1.61
161 Purified octamer binding transcription factors stimulate RNA polymerase III--mediated transcription of the 7SK RNA gene. Cell 1989 1.61
162 Effects of activation-defective TBP mutations on transcription initiation in yeast. Nature 1994 1.60
163 Multiple ribonucleic acid polymerases and ribonucleic acid synthesis during sea urchin development. Biochemistry 1970 1.60
164 Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID). Nucleic Acids Res 1991 1.59
165 Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters. Mol Cell Biol 1990 1.58
166 Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID. Genes Dev 1993 1.58
167 Human TFIIIC relieves chromatin-mediated repression of RNA polymerase III transcription and contains an intrinsic histone acetyltransferase activity. Mol Cell Biol 1999 1.58
168 Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression. Mol Cell Biol 1996 1.57
169 Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase I from the mouse myeloma, MOPC 315. J Biol Chem 1974 1.56
170 Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs. Mol Cell 1998 1.56
171 TFIIA induces conformational changes in TFIID via interactions with the basic repeat. Mol Cell Biol 1992 1.55
172 Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle. EMBO J 1998 1.54
173 A downstream initiation element required for efficient TATA box binding and in vitro function of TFIID. Nature 1990 1.53
174 Xenopus laevis histone genes: variant H1 genes are present in different clusters. Cell 1980 1.51
175 Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. Cell 2001 1.50
176 Altered levels of a 5 S gene-specific transcription factor (TFIIIA) during oogenesis and embryonic development of Xenopus laevis. J Biol Chem 1984 1.49
177 A dynamic model for PC4 coactivator function in RNA polymerase II transcription. Proc Natl Acad Sci U S A 1998 1.47
178 In vitro stimulation of specific RNA polymerase II-mediated transcription by the pseudorabies virus immediate early protein. Cell 1985 1.46
179 Octamer transcription factors 1 and 2 each bind to two different functional elements in the immunoglobulin heavy-chain promoter. Mol Cell Biol 1989 1.46
180 An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate. Mol Cell Biol 1989 1.45
181 Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells. Proc Natl Acad Sci U S A 1999 1.44
182 Activator-dependent transcription by mammalian RNA polymerase II: in vitro reconstitution with general transcription factors and cofactors. Methods Enzymol 1996 1.43
183 Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG. Proc Natl Acad Sci U S A 1990 1.43
184 TATA-binding protein residues implicated in a functional interplay between negative cofactor NC2 (Dr1) and general factors TFIIA and TFIIB. J Biol Chem 1995 1.41
185 Identification of an autonomously initiating RNA polymerase III holoenzyme containing a novel factor that is selectively inactivated during protein synthesis inhibition. Genes Dev 1997 1.40
186 Cloning and characterization of a TFIIIC2 subunit (TFIIIC beta) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors. Genes Dev 1995 1.39
187 TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes. EMBO J 2000 1.39
188 DNA-dependent RNA polymerase levels during the response of human peripheral lymphocytes to phytohemagglutinin. Cell 1975 1.39
189 A plant DNA-binding protein increases the number of active preinitiation complexes in a human in vitro transcription system. Genes Dev 1990 1.39
190 Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split. Mol Cell Biol 2001 1.38
191 Human transcription factor IIIC (TFIIIC). Purification, polypeptide structure, and the involvement of thiol groups in specific DNA binding. J Biol Chem 1989 1.38
192 Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro. Proc Natl Acad Sci U S A 1997 1.37
193 A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription. Proc Natl Acad Sci U S A 1998 1.37
194 Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis. Levels of activity during oocyte and embryonic development. J Biol Chem 1974 1.35
195 Engrailed, a homeodomain protein, can repress in vitro transcription by competition with the TATA box-binding protein transcription factor IID. Proc Natl Acad Sci U S A 1990 1.35
196 Recombinant yeast TFIID, a general transcription factor, mediates activation by the gene-specific factor USF in a chromatin assembly assay. Proc Natl Acad Sci U S A 1990 1.35
197 Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE. Proc Natl Acad Sci U S A 1990 1.34
198 RNA polymerase II cofactor PC2 facilitates activation of transcription by GAL4-AH in vitro. Mol Cell Biol 1994 1.34
199 A quick procedure for purification of functional recombinant proteins over-expressed in E.coli. Nucleic Acids Res 1991 1.33
200 Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase II from the mouse plasmacytoma, MOPC 315. J Biol Chem 1975 1.33
201 Purification and characterization of two forms of human transcription factor IIIC. J Biol Chem 1992 1.33
202 The ts13 mutation in the TAF(II)250 subunit (CCG1) of TFIID directly affects transcription of D-type cyclin genes in cells arrested in G1 at the nonpermissive temperature. Mol Cell Biol 1997 1.33
203 Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau). Proc Natl Acad Sci U S A 1992 1.33
204 Selective and accurate transcription of the Xenopus laevis 5S RNA genes in isolated chromatin by purified RNA polymerase III. Proc Natl Acad Sci U S A 1977 1.33
205 RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2. J Biol Chem 1997 1.31
206 Definition of the transcriptional activation domain of recombinant 43-kilodalton USF. Mol Cell Biol 1992 1.31
207 Binding site-dependent direct activation and repression of in vitro transcription by Drosophila homeodomain proteins. Cell 1990 1.30
208 Analysis of the role of TFIIE in basal transcription and TFIIH-mediated carboxy-terminal domain phosphorylation through structure-function studies of TFIIE-alpha. Mol Cell Biol 1995 1.30
209 Considerations of transcriptional control mechanisms: do TFIID-core promoter complexes recapitulate nucleosome-like functions? Proc Natl Acad Sci U S A 1997 1.30
210 Positive and negative regulation of the gene for transcription factor IIIA in Xenopus laevis oocytes. Genes Dev 1989 1.30
211 Fos and jun cooperate in transcriptional regulation via heterologous activation domains. Mol Cell Biol 1990 1.30
212 A bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID. Proc Natl Acad Sci U S A 1992 1.29
213 Sarkosyl defines three intermediate steps in transcription initiation by RNA polymerase III: application to stimulation of transcription by E1A. Genes Dev 1990 1.29
214 Control of class II gene transcription during in vitro nucleosome assembly. Methods Cell Biol 1991 1.28
215 Interaction between the N-terminal domain of the 230-kDa subunit and the TATA box-binding subunit of TFIID negatively regulates TATA-box binding. Proc Natl Acad Sci U S A 1994 1.27
216 DNA sequences and transcription factor interactions of active and inactive forms of mammalian 5 S RNA genes. J Biol Chem 1984 1.27
217 Potential RNA polymerase II-induced interactions of transcription factor TFIIB. Mol Cell Biol 1993 1.27
218 Transcriptional activation in yeast by the proline-rich activation domain of human CTF1. J Biol Chem 1993 1.26
219 Positive and negative TAF(II) functions that suggest a dynamic TFIID structure and elicit synergy with traps in activator-induced transcription. Mol Cell Biol 2001 1.26
220 A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements. Proc Natl Acad Sci U S A 2000 1.26
221 Transcription of specific adenovirus genes in isolated nuclei by exogenous RNA polymerases. J Biol Chem 1977 1.26
222 The conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth. Mol Cell Biol 1991 1.25
223 OCA-B integrates B cell antigen receptor-, CD40L- and IL 4-mediated signals for the germinal center pathway of B cell development. EMBO J 1998 1.25
224 CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues. Nucleic Acids Res 1997 1.24
225 The Drosophila 110-kDa transcription factor TFIID subunit directly interacts with the N-terminal region of the 230-kDa subunit. Proc Natl Acad Sci U S A 1993 1.24
226 The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity. Mol Cell Biol 1999 1.24
227 cDNA clone encoding Drosophila transcription factor TFIID. Proc Natl Acad Sci U S A 1990 1.24
228 A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA. Genes Dev 1993 1.24
229 DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III. Mol Cell 1998 1.23
230 Structure, function and expression of a murine homeobox protein AREC3, a homologue of Drosophila sine oculis gene product, and implication in development. Nucleic Acids Res 1996 1.23
231 Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC. Mol Cell Biol 1994 1.23
232 Utilization of signal transduction pathway by the human T-cell leukemia virus type I transcriptional activator tax. J Virol 1989 1.22
233 Multiple proteins bind to VA RNA genes of adenovirus type 2. Mol Cell Biol 1987 1.21
234 Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex. Mol Cell Biol 1998 1.21
235 The Xenopus B1 factor is closely related to the mammalian activator USF and is implicated in the developmental regulation of TFIIIA gene expression. Mol Cell Biol 1991 1.20
236 Identification of TFIID components required for transcriptional activation by upstream stimulatory factor. J Biol Chem 1993 1.20
237 Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappaB and Sp1. Mol Cell Biol 1998 1.19
238 Viral RNA synthesis and levels of DNA-dependent RNA polymerases during replication of adenovirus 2. J Virol 1975 1.18
239 Distinct molecular structures of nuclear class I, II, and III DNA-dependent RNA polymerases. Proc Natl Acad Sci U S A 1975 1.17
240 Encephalomyocarditis virus infection of mouse plasmacytoma cells. II. Effect on host RNA synthesis and RNA polymerases. J Virol 1974 1.17
241 Transcription factor TFIIB sites important for interaction with promoter-bound TFIID. Science 1993 1.17
242 Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III. Mol Cell Biol 1996 1.16
243 Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription. Proc Natl Acad Sci U S A 1995 1.16
244 The helix-loop-helix/leucine repeat transcription factor USF can be functionally regulated in a redox-dependent manner. J Biol Chem 1992 1.16
245 Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III. Mol Cell Biol 1999 1.16
246 Phosphorylation negatively regulates the function of coactivator PC4. Proc Natl Acad Sci U S A 1994 1.14
247 TFIIIC1 acts through a downstream region to stabilize TFIIIC2 binding to RNA polymerase III promoters. Mol Cell Biol 1996 1.14
248 Stable transcription complex on a class III gene in a minichromosome. Mol Cell Biol 1985 1.13
249 Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors. Proc Natl Acad Sci U S A 1995 1.12
250 Core promoter-specific function of a mutant transcription factor TFIID defective in TATA-box binding. Proc Natl Acad Sci U S A 1995 1.11
251 Cloning and characterization of human TAF20/15. Multiple interactions suggest a central role in TFIID complex formation. J Biol Chem 1996 1.10
252 Transcriptional regulation of c-fos. Cold Spring Harb Symp Quant Biol 1988 1.10
253 Cloning and expression of cDNA for human poly(ADP-ribose) polymerase. Proc Natl Acad Sci U S A 1987 1.09
254 Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit. J Biol Chem 1998 1.08
255 Purification, properties, and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase III from uninfected and adenovirus 2-infected KB cells. J Biol Chem 1977 1.08
256 Drosophila TAF(II)230 and the transcriptional activator VP16 bind competitively to the TATA box-binding domain of the TATA box-binding protein. Proc Natl Acad Sci U S A 1997 1.07
257 Serum response factor affects preinitiation complex formation by TFIID in vitro. New Biol 1991 1.07
258 Molecular cloning, expression, and characterization of the Drosophila 85-kilodalton TFIID subunit. Mol Cell Biol 1993 1.06
259 TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism. Mol Cell Biol 1999 1.06
260 Isolation and genomic arrangement of active and inactive forms of mammalian 5 S RNA genes. J Biol Chem 1984 1.06
261 Specific interactions and potential functions of human TAFII100. J Biol Chem 1997 1.05
262 Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF. Proc Natl Acad Sci U S A 2001 1.05
263 Identification of an octamer-binding site in the mouse kappa light-chain immunoglobulin enhancer. Mol Cell Biol 1989 1.05
264 Transcription of viral genes by RNA polymerase II in nuclei isolated from adenovirus 2 transformed cells. Biochemistry 1978 1.04
265 Nucleotide and amino acid sequence of RAP30. Nucleic Acids Res 1991 1.04
266 The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors. J Biol Chem 1997 1.02
267 Elucidation of three putative structural subdomains by comparison of primary structure of Xenopus and human RAP74. Nucleic Acids Res 1992 1.02
268 Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase III from the mouse plasmacytoma, MOPC 315. J Biol Chem 1976 1.01
269 The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter. Proc Natl Acad Sci U S A 1989 1.01
270 Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters. J Virol 1989 1.00
271 Transcription of specific genes in isolated nuclei by exogenous RNA polymerases. Cell 1977 1.00
272 Isolation and characterization of a cDNA encoding Drosophila transcription factor TFIIB. Proc Natl Acad Sci U S A 1992 0.99
273 The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear extracts. Proc Natl Acad Sci U S A 2000 0.99
274 3' IgH enhancer elements shift synergistic interactions during B cell development. J Immunol 1998 0.99
275 CTD-like sequences are important for transcriptional activation by the proline-rich activation domain of CTF1. Nucleic Acids Res 1994 0.98
276 Interaction between cell cycle regulator, E2F-1, and NF-kappaB mediates repression of HIV-1 gene transcription. J Biol Chem 1997 0.98
277 A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro. J Biol Chem 1995 0.97
278 Coactivation by OCA-B: definition of critical regions and synergism with general cofactors. Mol Cell Biol 1998 0.97
279 Isolation and characterization of monoclonal antibodies directed against subunits of human RNA polymerases I, II, and III. Exp Cell Res 2000 0.96
280 Assembly and DNA binding of recombinant Ku (p70/p80) autoantigen defined by a novel monoclonal antibody specific for p70/p80 heterodimers. J Cell Sci 1994 0.96
281 The transcriptional role of host DNA-dependent RNA polymerases in adenovirus-infected KB cells. Cold Spring Harb Symp Quant Biol 1975 0.95
282 Epitopes of the p70 and p80 (Ku) lupus autoantigens. J Immunol 1991 0.95
283 Structural conservation of putative functional motifs between Xenopus and human TFIIE-beta. Nucleic Acids Res 1992 0.95
284 Identification and characterization of a novel OCA-B isoform. implications for a role in B cell signaling pathways. Immunity 2001 0.95
285 Two forms of transcription factor TFIIIC in extracts from HeLa cells. Nucleic Acids Res 1987 0.94
286 Parvovirus H-1 expression: mapping of the abundant cytoplasmic transcripts and identification of promoter sites and overlapping transcription units. J Virol 1986 0.94
287 Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase III from the posterior silk gland of Bombyx mori. J Biol Chem 1976 0.94
288 Activation of the adenovirus EIIa late promoter by a single-point mutation which enhances binding of transcription factor IID. J Biol Chem 1988 0.93
289 Nuclear factor 1 (NF1) affects accurate termination and multiple-round transcription by human RNA polymerase III. EMBO J 2000 0.93
290 Transformation by homeobox genes can be mediated by selective transcriptional repression. EMBO J 1994 0.93
291 TATA box mimicry by TFIID: autoinhibition of pol II transcription. Cell 1998 0.93
292 Faithful gene transcription by eukaryotic RNA polymerases in reconstructed systems. Cold Spring Harb Symp Quant Biol 1978 0.92
293 Structural relationships of low molecular weight viral RNAs synthesized by RNA polymerase III in nuclei from adenovirus 2-infected cells. J Biol Chem 1978 0.92
294 Cell- and stage-specific high-level expression of TBP-related factor 2 (TRF2) during mouse spermatogenesis. Mech Dev 2001 0.92
295 Purification and characterization of human transcription factor IIIA. J Biol Chem 1994 0.92
296 Conserved structural motifs within the N-terminal domain of TFIID tau from Xenopus, mouse and human. Nucleic Acids Res 1992 0.91
297 Role of OCA-B in 3'-IgH enhancer function. J Immunol 2000 0.91
298 Conserved structural motifs between Xenopus and human TFIIB. Nucleic Acids Res 1991 0.90
299 Identification of a novel factor that interacts with an immunoglobulin heavy-chain promoter and stimulates transcription in conjunction with the lymphoid cell-specific factor OTF2. Mol Cell Biol 1990 0.90
300 Upstream stimulating factor affects human immunodeficiency virus type 1 (HIV-1) long terminal repeat-directed transcription in a cell-specific manner, independently of the HIV-1 subtype and the core-negative regulatory element. J Gen Virol 2001 0.90
301 Identification of USF as the ubiquitous murine factor that binds to and stimulates transcription from the immunoglobulin lambda 2-chain promoter. Nucleic Acids Res 1992 0.89
302 The human homologue of Drosophila TRF-proximal protein is associated with an RNA polymerase II-SRB complex. J Biol Chem 1999 0.88
303 Multiple forms of DNA-dependent RNA polymerases in Xenopus laevis. Rapid purification and structural and immunological properties. J Biol Chem 1983 0.88
304 The major histocompatibility complex class II Ea promoter requires TFIID binding to an initiator sequence. Mol Cell Biol 1996 0.88
305 Involvement of the basic repeat domain of TATA-binding protein (TBP) in transcription by RNA polymerases I, II, and III. J Biol Chem 1994 0.87
306 Characterization of the nucleotide requirement for elimination of the rate-limiting step in 5 S RNA gene transcription. J Biol Chem 1986 0.86
307 Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II. Nucleic Acids Res 1997 0.85
308 The gene-specific initiation factor USF (upstream stimulatory factor) bound at the adenovirus type 2 major late promoter: mass and three-dimensional structure. Proc Natl Acad Sci U S A 1987 0.85
309 Genetic and biochemical analyses of yeast TATA-binding protein mutants. J Biol Chem 1993 0.84
310 Downstream promoter sequences facilitate the formation of a specific transcription factor IID-promoter complex topology required for efficient transcription from the megalin/low density lipoprotein receptor-related protein 2 promoter. J Biol Chem 2000 0.84
311 Genetic analyses of NFKB1 and OCA-B function: defects in B cells, serum IgM level, and antibody responses in Nfkb1-/-Oca-b-/- mice. J Immunol 2000 0.84
312 The use of monoclonal antibodies for the characterization of a 5 S gene-specific transcription factor (IIIA) from Xenopus laevis. J Biol Chem 1983 0.84
313 Yeast transcription factor IID participates in cell-free transcription of a mammalian ribosomal protein TATA-less promoter. Biochem J 1992 0.84
314 Major transitions in histone gene expression do not occur during development in Xenopus laevis. Dev Biol 1986 0.84
315 B-cell-specific coactivator OCA-B: biochemical aspects, role in B-cell development and beyond. Cold Spring Harb Symp Quant Biol 1999 0.83
316 Anti-IgM antibodies down modulate mu-enhancer activity and OTF2 levels in LPS-stimulated mouse splenic B-cells. Nucleic Acids Res 1991 0.82
317 An RNA polymerase III-defective mutation in TATA-binding protein disrupts its interaction with a transcription factor IIIB subunit in drosophila cells. J Biol Chem 1997 0.82
318 Identification of two large subdomains in TFIIE-alpha on the basis of homology between Xenopus and human sequences. Nucleic Acids Res 1992 0.81
319 Functional analysis of the OCA-B promoter. J Immunol 2000 0.81
320 Characterization of the core promoter of the Na+/K(+)-ATPase alpha 1 subunit gene. Elements required for transcription by RNA polymerase II and RNA polymerase III in vitro. Eur J Biochem 1996 0.81
321 Imperfect conservation of a sigma factor-like subregion in Xenopus general transcription factor RAP30. Nucleic Acids Res 1992 0.81
322 Direct binding of yeast transcription factor (TFIID) to the ribosomal protein L32 (rpL32) TATA-less promoter sequence. FEBS Lett 1993 0.81
323 Critical role of the second stirrup region of the TATA-binding protein for transcriptional activation both in yeast and human. J Biol Chem 1997 0.81
324 Neonatal induction of a nuclear protein that binds to the c-fos enhancer. Proc Natl Acad Sci U S A 1989 0.80
325 Novobiocin interferes with the binding of transcription factors TFIIIA and TFIIIC to the promoters of class III genes. Nucleic Acids Res 1987 0.80
326 Initiator element binding protein TFII-I: a tale of two sites. Indian J Biochem Biophys 1994 0.79
327 Transcription factor OTF-1 interacts with two distinct DNA elements in the A gamma-globin gene promoter. Biochemistry 1991 0.78
328 Transcription of viral genes in chromatin from adenovirus 2 transformed cells by exogenous eukaryotic RNA polymerases. Nucleic Acids Res 1979 0.78
329 Overlapping transcription by RNA polymerases II and III of the Xenopus TFIIIA gene in somatic cells. J Biol Chem 1994 0.78
330 Function, structure, and regulation of eukaryotic nuclear RNA polymerases. Symp Soc Dev Biol 1976 0.78
331 Human GLI-2 is a tat activation response element-independent Tat cofactor. J Virol 2001 0.77
332 Characterization of the highly conserved TFIIA small subunit from Drosophila melanogaster. J Biol Chem 1994 0.77
333 The upstream stimulatory factor functionally interacts with the Alzheimer amyloid beta-protein precursor gene. Hum Mol Genet 1995 0.77
334 Multiple forms of DNA-dependent RNA polymerases in Xenopus laevis. Properties, purification, and subunit structure of class III RNA polymerases. J Biol Chem 1983 0.77
335 Delineation of DNA sequences that are important for in vitro transcription from the adenovirus EIIa late promoter. Mol Cell Biol 1988 0.75
336 Independent control of transcription initiations from two sites by an initiator-like element and TATA box in the human c-erbB-2 promoter. FEBS Lett 1994 0.75