Published in Proc Natl Acad Sci U S A on June 21, 1994
An unusual case of 'uncompetitive activation' by ascorbic acid: purification and kinetic properties of a myrosinase from Raphanus sativus seedlings. Biochem J (1999) 1.14
Cloning and expression of the inositol monophosphatase gene from Methanococcus jannaschii and characterization of the enzyme. Appl Environ Microbiol (1998) 1.07
Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli. J Biol Chem (2008) 1.00
Characterization of a tetrameric inositol monophosphatase from the hyperthermophilic bacterium Thermotoga maritima. Appl Environ Microbiol (1999) 0.92
Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase. Proc Natl Acad Sci U S A (1995) 0.91
Structural Studies of Medicago truncatula Histidinol Phosphate Phosphatase from Inositol Monophosphatase Superfamily Reveal Details of Penultimate Step of Histidine Biosynthesis in Plants. J Biol Chem (2016) 0.90
Molecular and biochemical characterization of a distinct type of fructose-1,6-bisphosphatase from Pyrococcus furiosus. J Bacteriol (2002) 0.89
Characterization and regulation of inositol monophosphatase activity in Mycobacterium smegmatis. Biochem J (2002) 0.85
Common-type acylphosphatase: steady-state kinetics and leaving-group dependence. Biochem J (1997) 0.84
Kinetic characterization of enzyme forms involved in metal ion activation and inhibition of myo-inositol monophosphatase. Biochem J (1995) 0.82
Toward a crystal-clear view of lithium's site of action. Proc Natl Acad Sci U S A (1994) 0.82
Inositol synthesis regulates the activation of GSK-3α in neuronal cells. J Neurochem (2014) 0.81
Cloning, expression, purification, crystallization and X-ray analysis of inositol monophosphatase from Mus musculus and Homo sapiens. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.81
In silico study on the substrate binding manner in human myo-inositol monophosphatase 2. J Mol Model (2011) 0.79
Improving lithium therapeutics by crystal engineering of novel ionic cocrystals. Mol Pharm (2013) 0.79
Bovine inositol monophosphatase: enzyme-metal-ion interactions studied by pre-equilibrium fluorescence spectroscopy. Biochem J (1996) 0.77
Plasma and Brain Pharmacokinetics of Previously Unexplored Lithium Salts. RSC Adv (2014) 0.77
Proteomic analysis of rat brains following exposure to electroconvulsive therapy. J Korean Med Sci (2009) 0.76
Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Mol Psychiatry (2015) 0.75
Multibody cofactor and substrate molecular recognition in the myo-inositol monophosphatase enzyme. Sci Rep (2016) 0.75
Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol (1987) 66.52
Inositol phosphates and cell signalling. Nature (1989) 17.78
The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature (1988) 14.43
Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. EMBO J (1991) 7.16
The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain. J Biol Chem (1980) 6.02
Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. Science (1988) 4.50
Enzyme-catalyzed phosphoryl transfer reactions. Annu Rev Biochem (1980) 4.32
Neural and developmental actions of lithium: a unifying hypothesis. Cell (1989) 4.13
Reaction mechanism of alkaline phosphatase based on crystal structures. Two-metal ion catalysis. J Mol Biol (1991) 3.33
Cocrystal structure of an editing complex of Klenow fragment with DNA. Proc Natl Acad Sci U S A (1988) 3.02
Hydrolysis of phosphate monoesters: a biological problem with multiple chemical solutions. Trends Biochem Sci (1992) 2.00
The purification and properties of myo-inositol monophosphatase from bovine brain. Biochem J (1988) 1.80
The dephosphorylation of inositol 1,4-bisphosphate to inositol in liver and brain involves two distinct Li+-sensitive enzymes and proceeds via inositol 4-phosphate. Biochem J (1988) 1.49
Why is uncompetitive inhibition so rare? A possible explanation, with implications for the design of drugs and pesticides. FEBS Lett (1986) 1.38
Structure of inositol monophosphatase, the putative target of lithium therapy. Proc Natl Acad Sci U S A (1992) 1.32
Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences. Trends Pharmacol Sci (1991) 1.29
Crystallographic studies of the catalytic mechanism of the neutral form of fructose-1,6-bisphosphatase. Biochemistry (1993) 1.27
cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme. Biochem J (1992) 1.23
Chemical and kinetic mechanism of the inositol monophosphatase reaction and its inhibition by Li+. Eur J Biochem (1993) 1.09
Kinetic studies with myo-inositol monophosphatase from bovine brain. Biochemistry (1990) 1.07
Structural similarities between fructose-1,6-bisphosphatase and inositol monophosphatase. Biochem Biophys Res Commun (1993) 1.05
Catalysis of the hydrolysis of phosphorylated pyridines by Mg(OH)+: a possible model for enzymatic phosphoryl transfer. Biochemistry (1990) 1.03
Probing the role of metal ions in the mechanism of inositol monophosphatase by site-directed mutagenesis. Eur J Biochem (1993) 0.98
Modification of myo-inositol monophosphatase by the arginine-specific reagent phenylglyoxal. Biochem J (1989) 0.89
Bovine inositol monophosphatase. Studies on the binding interactions with magnesium, lithium and phosphate ions. FEBS Lett (1993) 0.88
Disruption of phosphoinositide signalling by lithium. Biochem Soc Trans (1992) 0.79
The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry (1998) 65.11
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem (1966) 7.91
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype. Nat Neurosci (2000) 5.53
The uptake of [3H]GABA by slices of rat cerebral cortex. J Neurochem (1968) 5.05
Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase. Nature (1985) 4.96
Continuity of care and trust in one's physician: evidence from primary care in the United States and the United Kingdom. Fam Med (2001) 4.54
Comparison of standards in training and non-training practices. J R Coll Gen Pract (1985) 4.44
Qualitative methods in research on healthcare quality. Qual Saf Health Care (2002) 4.42
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci U S A (1986) 3.97
Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med (1998) 3.91
Role of transmitter uptake mechanisms in synaptic neurotransmission. Br J Pharmacol (1971) 3.82
What do we know about how to do audit and feedback? Pitfalls in applying evidence from a systematic review. BMC Health Serv Res (2005) 3.51
Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain. J Neurochem (1970) 3.42
Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria. Arch Biochem Biophys (1977) 3.40
Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation. J Clin Invest (1986) 3.36
Abnormal ion permeation through cystic fibrosis respiratory epithelium. Science (1983) 3.31
Impact of the population at risk of diabetes on projections of diabetes burden in the United States: an epidemic on the way. Diabetologia (2006) 3.28
The role of uptake2 in the extraneuronal metabolism of catecholamines in the isolated rat heart. Br J Pharmacol (1969) 3.25
Changing the clinical behavior of doctors: a psychological framework. Qual Health Care (1996) 3.22
Electrotonic coupling between neurons in cat inferior olive. J Neurophysiol (1974) 3.20
Inhibition of catecholamine Uptake-2 by steroids in the isolated rat heart. Br J Pharmacol (1970) 3.07
Model for directly assessing and improving clinical competence and performance in revalidation of clinicians. BMJ (2001) 3.05
Features of primary care associated with variations in process and outcome of care of people with diabetes. Br J Gen Pract (2001) 2.95
Opiate analgesics inhibit substance P release from rat trigeminal nucleus. Nature (1977) 2.74
Clozapine for the treatment of adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry (1992) 2.68
The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60
Release of gamma-aminobutyric acid from inhibitory nerves of lobster. Proc Natl Acad Sci U S A (1966) 2.47
Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease. J Neurol Neurosurg Psychiatry (1985) 2.47
Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes. Cochrane Database Syst Rev (2005) 2.46
Differentiating between audit and research: postal survey of health authorities' views. BMJ (1999) 2.41
Quality improvement research: understanding the science of change in health care. Qual Saf Health Care (2002) 2.41
Differentiation of atypical atrioventricular node re-entrant tachycardia from orthodromic reciprocating tachycardia using a septal accessory pathway by the response to ventricular pacing. J Am Coll Cardiol (2001) 2.40
Flavoproteins of the mitochondrial respiratory chain. Proc Natl Acad Sci U S A (1967) 2.40
Left in limbo: patients' views on care across the primary/secondary interface. Qual Health Care (1999) 2.38
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. Gastroenterology (2001) 2.36
Multiple opiate receptor sites on primary afferent fibres. Nature (1980) 2.34
Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis. Mol Ther (2000) 2.34
Amiloride inhalation therapy in cystic fibrosis. Influence on ion content, hydration, and rheology of sputum. Am Rev Respir Dis (1993) 2.31
Jumonji, a nuclear protein that is necessary for normal heart development. Circ Res (2000) 2.26
Nontuberculous mycobacteria in adult patients with cystic fibrosis. Chest (1992) 2.25
Improved recovery of mycobacteria from respiratory secretions of patients with cystic fibrosis. J Clin Microbiol (1993) 2.22
The possible existence of multiple receptors for substance P. Naunyn Schmiedebergs Arch Pharmacol (1982) 2.18
A split binding site for transcription factor tau on the tRNA3Glu gene. EMBO J (1985) 2.16
In vivo intracellular recording and perturbation of persistent activity in a neural integrator. Nat Neurosci (2001) 2.13
Evidence for reduced Cl- and increased Na+ permeability in cystic fibrosis human primary cell cultures. J Physiol (1988) 2.10
Effectiveness of screening and monitoring tests for diabetic retinopathy--a systematic review. Diabet Med (2000) 2.10
Metastatic malignant mesothelioma presenting as colonic polyps. Hum Pathol (1997) 2.09
The physiologic disposition and metabolism of norepinephrine in immunosympathectomized animals. J Pharmacol Exp Ther (1966) 2.03
GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors. J Neurochem (1971) 2.00
Trans-synaptic regulation of growth and development of adrenergic neurones in a mouse sympathetic ganglion. Brain Res (1971) 1.99
Differential distribution of 5HT1D- and 5HT1B-immunoreactivity within the human trigemino-cerebrovascular system: implications for the discovery of new antimigraine drugs. Cephalalgia (1997) 1.99
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc Natl Acad Sci U S A (1988) 1.99
Comparison of the clinical manifestations of cystic fibrosis in black and white patients. J Pediatr (1998) 1.97
Preferential coassembly of alpha4 and delta subunits of the gamma-aminobutyric acidA receptor in rat thalamus. Mol Pharmacol (1999) 1.96
Release of dopamine from dendrites in rat substantia nigra. Nature (1976) 1.95
Orphan G-protein-coupled receptors and natural ligand discovery. Trends Pharmacol Sci (2001) 1.94
Effects of treatment with formoterol on bronchoprotection against methacholine. Am J Med (1998) 1.94
Reduced uptake of tritiated noradrenaline in tissues of immunosympathectomized animals. Nature (1965) 1.91
Autoradiographic localization of 3 H-GABA in rat retina. Nat New Biol (1972) 1.90
Effects of phenoxybenzamine on the uptake and metabolism of noradrenaline in the rat heart and vas deferens. Br J Pharmacol (1969) 1.90
URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit. Science (1986) 1.87
Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis. Am Rev Respir Dis (1985) 1.87
Multiple tachykinin binding sites in peripheral tissues and in brain. Eur J Pharmacol (1986) 1.86
Identification of common cystic fibrosis mutations in African-Americans with cystic fibrosis increases the detection rate to 75%. Am J Hum Genet (1997) 1.84
Features of primary health care teams associated with successful quality improvement of diabetes care: a qualitative study. Fam Pract (2001) 1.84
Catecholamine uptake processes. Br Med Bull (1973) 1.83
Uptake and metabolism of gamma-aminobutyric acid by neurones and glial cells. Biochem Pharmacol (1975) 1.83
The inhibition of noradrenaline uptake by drugs. Adv Drug Res (1965) 1.82
Use of catechol O-methyltransferase for the enzyme radiochemical assay of dopamine. J Neurochem (1973) 1.82
Pulmonary epithelial sodium-channel dysfunction and excess airway liquid in pseudohypoaldosteronism. N Engl J Med (1999) 1.81
The purification and properties of myo-inositol monophosphatase from bovine brain. Biochem J (1988) 1.80
Capsaicin-induced depletion of substance P from primary sensory neurones. Brain Res (1978) 1.80
Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death. Proc Natl Acad Sci U S A (1994) 1.79
Dopamine receptors in the brain. Science (1975) 1.79
Altered intestinal chloride transport in cystic fibrosis. FASEB J (1988) 1.78
Neurochemical characteristics of early and late onset types of Alzheimer's disease. Br Med J (Clin Res Ed) (1984) 1.78
Decreased sodium ion absorption across nasal epithelium of very premature infants with respiratory distress syndrome. J Pediatr (1997) 1.77
Best place of care for older people after acute and during subacute illness: a systematic review. J Health Serv Res Policy (2000) 1.75
Quality assurance in general practice: the state of the art in Europe. Fam Pract (1994) 1.75
The costs and benefits of asking patients for their opinions about general practice. Fam Pract (1996) 1.73
Uptake mechanisms for neurotransmitter amines. Biochem Pharmacol (1974) 1.73
Development of guidelines to facilitate improved support of South Asian carers by primary health care teams. Qual Health Care (2001) 1.72
Structural study of inferior olivary nucleus of the cat: morphological correlates of electrotonic coupling. J Neurophysiol (1974) 1.71
Benign missense variations in the cystic fibrosis gene. Am J Hum Genet (1990) 1.67
Specific labelling of a constituent polypeptide of bovine heart mitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone reductase by the inhibitor diphenyleneiodonium. Biochem J (1977) 1.66
Characteristics of general practices associated with emergency admission rates to hospital: a cross-sectional study. Emerg Med J (2011) 1.65
Tissue selectivity of substance P alkyl esters: suggesting multiple receptors. Eur J Pharmacol (1983) 1.65
Introducing a quality improvement programme to primary healthcare teams. Qual Health Care (1998) 1.64
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8. J Biol Chem (2000) 1.63
Sodium dependence of transmitter uptake at adrenergic nerve terminals. Mol Pharmacol (1966) 1.63
Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms. J Clin Invest (1989) 1.62
A post-mortem study of the cholinergic and GABA systems in senile dementia. Brain (1982) 1.62
Working from upstream to improve health care: the IHI interdisciplinary professional education collaborative. Jt Comm J Qual Improv (1996) 1.61
The release of gamma-aminobutyric acid during inhibition in the cat visual cortex. J Physiol (1971) 1.59
Uptake, storage and metabolism of norepinephrine in tissues of the developing rat. J Pharmacol Exp Ther (1967) 1.58
Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia. Brain (1974) 1.57
In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J Neurochem (1993) 1.56