Published in Mol Cell Biol on February 01, 1981
Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication. Proc Natl Acad Sci U S A (1982) 3.44
Homologous recombination between overlapping thymidine kinase gene fragments stably inserted into a mouse cell genome. Mol Cell Biol (1984) 1.88
Differences in intracellular DNA ligation after microinjection and transfection. Mol Cell Biol (1984) 1.73
Tumor induction by direct injection of cloned v-src DNA into chickens. Proc Natl Acad Sci U S A (1983) 1.53
Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences. Mol Cell Biol (1983) 1.35
Co-amplification of double minute chromosomes, multiple drug resistance, and cell surface P-glycoprotein in DNA-mediated transformants of mouse cells. Mol Cell Biol (1984) 1.34
Expression and stabilization of microinjected plasmids containing the herpes simplex virus thymidine kinase gene and polyoma virus DNA in mouse cells. Mol Cell Biol (1983) 1.16
ADP-ribosylation is involved in the integration of foreign DNA into the mammalian cell genome. Nucleic Acids Res (1988) 1.12
Fate of exogenous recombinant plasmids introduced into mouse and human cells. Nucleic Acids Res (1985) 1.06
Expression of adenovirus type 12 early region 1 in KB cells transformed by recombinants containing the gene. J Virol (1983) 1.04
Plasmids containing mouse rDNA do not recombine with cellular ribosomal genes when introduced into cultured mouse cells. Mol Cell Biol (1984) 0.99
Intrachromosomal recombination mediated by papovavirus large T antigens. J Virol (1990) 0.96
Unstable expression and amplification of a transfected oncogene in confluent and subconfluent cells. Mol Cell Biol (1985) 0.92
Deletions in the SV40 late polyadenylation region downstream of the AATAAA mediate similar effects on expression in various mammalian cell lines. Nucleic Acids Res (1988) 0.86
Unstable transformation of mouse 3T3 cells by transfection with DNA from normal human lymphocytes. EMBO J (1984) 0.86
DNA-mediated gene transfer of beta-aspartylhydroxamate resistance into Chinese hamster ovary cells. Proc Natl Acad Sci U S A (1981) 0.84
Satellite DNA induces unstable expression of the adjacent herpes simplex virus tk gene cotransfected in mouse cells. Mol Cell Biol (1988) 0.79
Human papillomavirus type 6b DNA required for initiation but not maintenance of transformation of C127 mouse cells. J Virol (1990) 0.79
Integration of a vector containing rodent repetitive elements in the rat genome. Nucleic Acids Res (1987) 0.78
Introduction and expression of the bacterial PaeR7 restriction endonuclease gene in mouse cells containing the PaeR7 methylase. Nucleic Acids Res (1988) 0.78
Differential expression of mouse beta/goat beta c, mouse beta/goat beta F, and mouse beta/goat epsilon II hybrid globin genes in murine erythroleukemia cells. Mol Cell Biol (1986) 0.75
Gene targeting in rat embryo fibroblasts promoted by the polyomavirus large T antigen. Nucleic Acids Res (1996) 0.75
A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol (1967) 106.91
Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. Proc Natl Acad Sci U S A (1979) 72.18
SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS. Science (1964) 24.40
Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell (1979) 21.15
Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell (1977) 18.95
Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature (1977) 16.54
Genetic and physical linkage of exogenous sequences in transformed cells. Cell (1980) 6.67
The transfer and stable integration of the HSV thymidine kinase gene into mouse cells. Cell (1978) 6.38
Insertion of synthetic copies of human globin genes into bacterial plasmids. Nucleic Acids Res (1978) 5.99
Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus. Gene (1979) 5.09
Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA. Proc Natl Acad Sci U S A (1977) 4.35
Microbial transformation and transfection. Annu Rev Microbiol (1966) 3.73
Transformation of the gene for hypoxanthine phosphoribosyltransferase. Somatic Cell Genet (1979) 2.42
DNA-mediated gene transfer of a circular plasmid into murine cells. Proc Natl Acad Sci U S A (1979) 2.02
Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells. Proc Natl Acad Sci U S A (1977) 1.97
Chromosome-mediated gene transfer results in two classes of unstable transformants. Proc Natl Acad Sci U S A (1980) 1.74
Phenotype stabilisation and integration of transferred material in chromosome-mediated gene transfer. Nature (1979) 1.73
A herpes simplex virus 1 integration site in the mouse genome defined by somatic cell genetic analysis. Cell (1978) 1.54
Molecular analysis of chromosome-mediated gene transfer. Proc Natl Acad Sci U S A (1979) 1.31
Ultrastructure of double minutes from a human tumor cell line. J Cell Biol (1979) 0.99
Somatic cell genetic analysis of transgenome integration. Somatic Cell Genet (1979) 0.87
Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci U S A (1980) 5.47
The status of the gene map of the human chromosomes. Science (1977) 5.44
Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes. Proc Natl Acad Sci U S A (1982) 5.30
Somatic cell genetics and gene families. Science (1983) 4.61
A conversational system for the computer analysis of nucleic acid sequences. Nucleic Acids Res (1981) 4.07
Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells. Proc Natl Acad Sci U S A (1975) 3.91
Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene. Proc Natl Acad Sci U S A (1985) 3.91
Mechanisms and applications of DNA-mediated gene transfer in mammalian cells - a review. Gene (1981) 3.46
Gene transfer, expression, and molecular cloning of the human transferrin receptor gene. Cell (1984) 3.42
A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels. J Histochem Cytochem (1973) 3.33
Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants. Proc Natl Acad Sci U S A (1981) 3.21
The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence. Cell (1984) 3.14
Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of Drosophila. Cell (1984) 2.89
Controlled production of proliferating somatic cell hybrids. J Cell Biol (1970) 2.78
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. Proc Natl Acad Sci U S A (1999) 2.76
A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids. Exp Cell Res (1977) 2.71
Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 2.65
International system for human gene nomenclature (1979) ISGN (1979). Cytogenet Cell Genet (1979) 2.58
Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome. Proc Natl Acad Sci U S A (1985) 2.58
The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21. J Exp Med (1973) 2.57
Linkage analysis in man by somatic cell genetics. Nature (1973) 2.33
Integration and stable germ line transmission of genes injected into mouse pronuclei. Science (1981) 2.31
Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Methods Enzymol (1983) 2.23
Two steps in the evolution of Antennapedia-class vertebrate homeobox genes. Proc Natl Acad Sci U S A (1989) 2.23
Spatial restriction in expression of a mouse homoeo box locus within the central nervous system. Nature (1986) 2.16
Molecular cloning and structural analysis of murine thymidine kinase genomic and cDNA sequences. Mol Cell Biol (1985) 2.13
Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome. Somatic Cell Genet (1975) 2.11
Chromosomal location of structural genes encoding murine immunoglobulin lambda light chains. Genetics of murine lambda light chains. J Exp Med (1981) 2.07
DNA-mediated gene transfer of a circular plasmid into murine cells. Proc Natl Acad Sci U S A (1979) 2.02
Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain. Somatic Cell Genet (1976) 1.98
Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells. Proc Natl Acad Sci U S A (1977) 1.97
Assignment of the gene for adenine phosphoribosyltransferase to human chromosome 16 by mouse-human somatic cell hybridization. Proc Natl Acad Sci U S A (1974) 1.97
Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem Genet (1970) 1.96
A new era in mammalian gene mapping: somatic cell genetics and recombinant DNA methodologies. Nature (1981) 1.96
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (1974) 1.95
Assignment of three human genes to chromosomes (LDH-A to 11, TK to 17, and IDH to 20) and evidence for translocation between human and mouse chromosomes in somatic cell hybrids (thymidine kinase-lactate dehydrogenase A-isocitrate dehydrogenase-C-11, E-17, and F-20 chromosomes). Proc Natl Acad Sci U S A (1972) 1.93
Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms. Infect Immun (1994) 1.93
Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus. Cell (1985) 1.92
Chromosomal assignment of the mouse kappa light chain genes. Proc Natl Acad Sci U S A (1979) 1.87
Receptors for human alpha and beta interferon but not for gamma interferon are specified by human chromosome 21. Proc Natl Acad Sci U S A (1984) 1.86
Human chromosome 7 carries the beta 2 interferon gene. Proc Natl Acad Sci U S A (1986) 1.82
Starch gel electrophoretic phenotypes of mouse times human somatic cell hybrids and mouse isozyme polymorphisms. In Vitro (1974) 1.81
Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes. Nature (1985) 1.81
A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes. Nucleic Acids Res (1995) 1.80
A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases. Anal Biochem (1973) 1.78
Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains. J Exp Med (1980) 1.76
Chromosome-mediated gene transfer results in two classes of unstable transformants. Proc Natl Acad Sci U S A (1980) 1.74
Co-transfer of human X-linked markers into murine somatic cells via isolated metaphase chromosomes. Proc Natl Acad Sci U S A (1978) 1.73
Phenotype stabilisation and integration of transferred material in chromosome-mediated gene transfer. Nature (1979) 1.73
Genetic analysis with man-mouse somatic cell hybrids. Linkage between human lactate dehydrogenase A and B and peptidase B. Nature (1970) 1.73
An efficient cis-element discovery method using multiple sequence comparisons based on evolutionary relationships. Genomics (2001) 1.72
Sequence analysis of the murine Hox-2.2, -2.3, and -2.4 homeo boxes: evolutionary and structural comparisons. Genomics (1987) 1.71
Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice. Proc Natl Acad Sci U S A (1989) 1.69
Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem Genet (1969) 1.69
Karyotype analysis utilizing differentially stained constitutive heterochromatin of human and murine chromosomes. Chromosoma (1971) 1.68
Cotransfer of thymidine kinase and galactokinase genes by chromosome-mediated gene transfer. Proc Natl Acad Sci U S A (1978) 1.67
Chromosome polymorphism in American Negro and White populations. Nature (1971) 1.66
The evolution of the vertebrate Dlx gene family. Proc Natl Acad Sci U S A (1996) 1.64
Chromosomal abnormalities in the human population: estimation of rates based on New Haven newborn study. Science (1970) 1.64
Biological detection of specific mRNA molecules by microinjection. Proc Natl Acad Sci U S A (1979) 1.63
Cloning and expression of murine lymphotoxin cDNA. J Immunol (1987) 1.62
Parasexual approaches to the genetics of man. Annu Rev Genet (1975) 1.62
Genetic complementation in heterokaryons of human fibroblasts defective in cobalamin metabolism. Proc Natl Acad Sci U S A (1975) 1.62
Expression of liver phenotypes in cultured mouse hepatoma cells. J Natl Cancer Inst (1980) 1.60
Pluripotent teratocarcinoma-thymus somatic cell hybrids. Cell (1976) 1.60
Mouse-human heterokaryon analysis with a 33258 Hoechst-Giemsa technique. J Cell Biol (1975) 1.59
Embryonal carcinoma cells (and their somatic cell hybrids) are resistant to infection by the murine parvovirus MVM, which does infect other teratocarcinoma-derived cell lines. J Cell Physiol (1977) 1.58
Detection of homeobox genes in development and evolution. Proc Natl Acad Sci U S A (1991) 1.55
A herpes simplex virus 1 integration site in the mouse genome defined by somatic cell genetic analysis. Cell (1978) 1.54
Cyclic changes in enzyme activity in synchronized mammalian cell cultures. Science (1968) 1.53
Chromosomal assignment of a family of human oncogenes. Proc Natl Acad Sci U S A (1983) 1.53
Expansion of the Hox gene family and the evolution of chordates. Proc Natl Acad Sci U S A (1993) 1.52
Assignment of a gene for adenosine deaminase to human chromosome 20. Hum Hered (1974) 1.52
The William Allan Memorial Award address: Reverse genetics and beyond. Am J Hum Genet (1984) 1.52
DNA sequence associated with chromosome translocations in mouse plasmacytomas. Proc Natl Acad Sci U S A (1982) 1.51
Assignment of nucleoside phosphorylase to D-14 and localization of X-linked loci in man by somatic cell genetics. Nat New Biol (1973) 1.51
Tay-Sachs' and Sandhoff's diseases: the assignment of genes for hexosaminidase A and B to individual human chromosomes. Proc Natl Acad Sci U S A (1975) 1.49
Fibroblast interferon in man is coded by two loci on separate chromosomes. Cell (1979) 1.49
Assignment of the gene for galactokinase to human chromosome 17 and its regional localisation to band q21-22. Nature (1974) 1.49
The somatic cell genetics of human interferon: assignment of human interferon loci to chromosomes 2 and 5. Proc Natl Acad Sci U S A (1974) 1.46
Stable association of the human transgenome and host murine chromosomes demonstrated with trispecific microcell hybrids. Proc Natl Acad Sci U S A (1977) 1.45
The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes. EMBO J (1982) 1.44
Isolation, chromosomal localization, and nucleotide sequence of the human HOX 1.4 homeobox. Genomics (1989) 1.43
The PKU locus in man is on chromosome 12. Am J Hum Genet (1984) 1.42
Transcriptional regulation by iron of the gene for the transferrin receptor. Mol Cell Biol (1986) 1.42
Localization and induction of the human thymidine kinase gene by adenovirus 12. Nat New Biol (1973) 1.42
Phylogenetic reconstruction of vertebrate Hox cluster duplications. Mol Biol Evol (1997) 1.41
Murine alpha-fetoprotein and albumin: two evolutionarily linked proteins encoded on the same mouse chromosome. Somatic Cell Genet (1981) 1.41
Identification of human genomic clones coding the major histocompatibility antigens HLA-a2 and HLA-B7 by DNA-mediated gene transfer. Proc Natl Acad Sci U S A (1982) 1.39
Linkage of isozyyme loci in the mouse: phosphoglucomutase-2 (Pgm-2), mitochondrial NADP malate dehydrogenase (Mod-2), and dipeptidase-1 (Dip-1). Biochem Genet (1971) 1.37
Linkage analysis using somatic cell hybrids. Adv Hum Genet (1972) 1.36
Modification of expression and cis-regulation of Hoxc8 in the evolution of diverged axial morphology. Proc Natl Acad Sci U S A (1998) 1.36
Antibodies to a cell-surface component coded by human chromosome 21 inhibit action of interferon. Nature (1976) 1.35
Molecular cloning of the c-fms locus and its assignment to human chromosome 5. J Virol (1983) 1.33
Mitochondrial malate dehydrogenase and malic enzyme: Mendelian inherited electrophoretic variants in the mouse. Biochem Genet (1970) 1.33
Localization of the casein gene family to a single mouse chromosome. J Cell Biol (1982) 1.33
Human serum albumin phenotype activation in mouse hepatoma--human leukocyte cell hybrids. Science (1974) 1.33