Published in Cell on October 01, 1978
Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules. Mol Cell Biol (1982) 7.49
Chromosomal location of structural genes encoding murine immunoglobulin lambda light chains. Genetics of murine lambda light chains. J Exp Med (1981) 2.07
Polymorphism and complexity of the human DC and murine I-A alpha chain genes. EMBO J (1983) 1.50
Deoxyribonucleic acid-mediated gene transfer in mammalian cells: molecular analysis of unstable transformants and their progression to stability. Mol Cell Biol (1981) 1.47
Transformation by iontophoretic microinjection of DNA: multiple integrations without tandem insertions. Mol Cell Biol (1983) 1.37
Molecular analysis of chromosome-mediated gene transfer. Proc Natl Acad Sci U S A (1979) 1.31
A general high-efficiency procedure for production of microcell hybrids. Proc Natl Acad Sci U S A (1981) 1.22
Genomic analysis using a yeast artificial chromosome library with mouse DNA inserts. Proc Natl Acad Sci U S A (1992) 1.07
A genetic map of mouse chromosome 12 composed of polymorphic DNA fragments. J Exp Med (1984) 1.02
Eucaryotic chromosome transfer: production of a murine-specific cosmid library from a neor-linked fragment of murine chromosome 17. Mol Cell Biol (1986) 1.02
Integration of Ecogpt and SV40 early region sequences into human chromosome 17: a dominant selection system in whole cell and microcell human-mouse hybrids. EMBO J (1983) 0.99
Genetic and molecular analysis of the proximal region of the mouse t-complex using new molecular probes and partial t-haplotypes. Genetics (1990) 0.98
Random cloning of genes from mouse chromosome 17. Proc Natl Acad Sci U S A (1987) 0.89
Testis-/embryo-expressed genes are clustered in the mouse H-2K region. Proc Natl Acad Sci U S A (1992) 0.85
New molecular markers for the distal end of the t-complex and their relationships to mutations affecting mouse development. Genetics (1992) 0.78
Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci U S A (1980) 5.47
The status of the gene map of the human chromosomes. Science (1977) 5.44
Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes. Proc Natl Acad Sci U S A (1982) 5.30
Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus. Gene (1979) 5.09
[125I]deoxycytidine used in a rapid, sensitive, and specific assay for herpes simplex virus type 1 thymidine kinase. J Virol (1977) 4.88
Somatic cell genetics and gene families. Science (1983) 4.61
Stable expression in mouse cells of nuclear neoantigen after transfer of a 3.4-megadalton cloned fragment of Epstein-Barr virus DNA. Proc Natl Acad Sci U S A (1982) 4.23
A conversational system for the computer analysis of nucleic acid sequences. Nucleic Acids Res (1981) 4.07
Possible peptide chain termination mutants in thymide kinase gene of a mammalian virus, herpes simplex virus. Proc Natl Acad Sci U S A (1975) 4.00
Transfer of the human gene for hypoxanthine-guanine phosphoribosyltransferase via isolated human metaphase chromosomes into mouse L-cells. Proc Natl Acad Sci U S A (1975) 3.91
Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene. Proc Natl Acad Sci U S A (1985) 3.91
Mechanisms and applications of DNA-mediated gene transfer in mammalian cells - a review. Gene (1981) 3.46
Gene transfer, expression, and molecular cloning of the human transferrin receptor gene. Cell (1984) 3.42
A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels. J Histochem Cytochem (1973) 3.33
Structure and function of herpesvirus genomes. I. comparison of five HSV-1 and two HSV-2 strains by cleavage their DNA with eco R I restriction endonuclease. J Virol (1975) 3.32
Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants. Proc Natl Acad Sci U S A (1981) 3.21
The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence. Cell (1984) 3.14
5'-Terminal nucleotide sequence of Escherichia coli lactose repressor mRNA: features of translational initiation and reinitiation sites. Proc Natl Acad Sci U S A (1977) 3.14
Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of Drosophila. Cell (1984) 2.89
Herpes simplex virus triggers and then disarms a host antiviral response. J Virol (2001) 2.82
Controlled production of proliferating somatic cell hybrids. J Cell Biol (1970) 2.78
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. Proc Natl Acad Sci U S A (1999) 2.76
Signals for site-specific cleavage of HSV DNA: maturation involves two separate cleavage events at sites distal to the recognition sequences. Cell (1985) 2.74
A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids. Exp Cell Res (1977) 2.71
Two Epstein-Barr viral nuclear neoantigens distinguished by gene transfer, serology, and chromosome binding. Proc Natl Acad Sci U S A (1983) 2.68
Herpes simplex virus ICP0 mutants are hypersensitive to interferon. J Virol (2000) 2.66
Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 2.65
Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs. J Virol (1994) 2.64
Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome. Proc Natl Acad Sci U S A (1985) 2.58
International system for human gene nomenclature (1979) ISGN (1979). Cytogenet Cell Genet (1979) 2.58
The linkage of genes for the human interferon-induced antiviral protein and indophenol oxidase-B traits to chromosome G-21. J Exp Med (1973) 2.57
Cells that constitutively express the herpes simplex virus immediate-early protein ICP4 allow efficient activation of viral delayed-early genes in trans. J Virol (1985) 2.40
Construction of a double-jointed herpes simplex viral DNA molecule: inverted repeats are required for segment inversion, and direct repeats promote deletions. Virology (1981) 2.39
Linkage analysis in man by somatic cell genetics. Nature (1973) 2.33
Identification of Epstein-Barr nuclear antigen polypeptide in mouse and monkey cells after gene transfer with a cloned 2.9-kilobase-pair subfragment of the genome. Proc Natl Acad Sci U S A (1984) 2.32
Integration and stable germ line transmission of genes injected into mouse pronuclei. Science (1981) 2.31
Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2. J Virol (1984) 2.29
Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection. Methods Enzymol (1983) 2.23
Two steps in the evolution of Antennapedia-class vertebrate homeobox genes. Proc Natl Acad Sci U S A (1989) 2.23
Genetic and physical evidence for the polarity of transcription of the thymidine kinase gene of herpes simplex virus. Virology (1980) 2.22
Spatial restriction in expression of a mouse homoeo box locus within the central nervous system. Nature (1986) 2.16
Evidence that herpes simplex virus VP16 is required for viral egress downstream of the initial envelopment event. J Virol (2000) 2.15
Construction in vitro and rescue of a thymidine kinase-deficient deletion mutation of herpes simplex virus. Nature (1980) 2.14
Molecular cloning and structural analysis of murine thymidine kinase genomic and cDNA sequences. Mol Cell Biol (1985) 2.13
Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome. Somatic Cell Genet (1975) 2.11
Chromosomal location of structural genes encoding murine immunoglobulin lambda light chains. Genetics of murine lambda light chains. J Exp Med (1981) 2.07
DNA-mediated gene transfer of a circular plasmid into murine cells. Proc Natl Acad Sci U S A (1979) 2.02
Herpes simplex virus VP16 rescues viral mRNA from destruction by the virion host shutoff function. EMBO J (1996) 1.99
Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain. Somatic Cell Genet (1976) 1.98
Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells. Proc Natl Acad Sci U S A (1977) 1.97
Assignment of the gene for adenine phosphoribosyltransferase to human chromosome 16 by mouse-human somatic cell hybridization. Proc Natl Acad Sci U S A (1974) 1.97
Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem Genet (1970) 1.96
The herpes simplex virus vhs protein induces endoribonucleolytic cleavage of target RNAs in cell extracts. J Virol (1999) 1.96
A new era in mammalian gene mapping: somatic cell genetics and recombinant DNA methodologies. Nature (1981) 1.96
Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state. Science (1974) 1.95
Assignment of three human genes to chromosomes (LDH-A to 11, TK to 17, and IDH to 20) and evidence for translocation between human and mouse chromosomes in somatic cell hybrids (thymidine kinase-lactate dehydrogenase A-isocitrate dehydrogenase-C-11, E-17, and F-20 chromosomes). Proc Natl Acad Sci U S A (1972) 1.93
Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41. J Gen Virol (1992) 1.92
Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus. Cell (1985) 1.92
In vitro suppression of UAG and UGA mutants in the thymidine kinase gene of herpes simplex virus. Proc Natl Acad Sci U S A (1979) 1.88
Chromosomal assignment of the mouse kappa light chain genes. Proc Natl Acad Sci U S A (1979) 1.87
Receptors for human alpha and beta interferon but not for gamma interferon are specified by human chromosome 21. Proc Natl Acad Sci U S A (1984) 1.86
Herpes simplex virus thymidine kinase transcripts are absent from both nucleus and cytoplasm during infection in the presence of cycloheximide. J Virol (1980) 1.86
Elongation by Escherichia coli RNA polymerase is blocked in vitro by a site-specific DNA binding protein. J Biol Chem (1990) 1.84
Human chromosome 7 carries the beta 2 interferon gene. Proc Natl Acad Sci U S A (1986) 1.82
Starch gel electrophoretic phenotypes of mouse times human somatic cell hybrids and mouse isozyme polymorphisms. In Vitro (1974) 1.81
Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes. Nature (1985) 1.81
Nucleotide sequence of a 5S ribosomal RNA gene in the sea urchin Lytechinus variegatus. Nucleic Acids Res (1980) 1.81
A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes. Nucleic Acids Res (1995) 1.80
A new electrophoretic-autoradiographic method for the visual detection of phosphotransferases. Anal Biochem (1973) 1.78
Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains. J Exp Med (1980) 1.76
Chromosome-mediated gene transfer results in two classes of unstable transformants. Proc Natl Acad Sci U S A (1980) 1.74
Co-transfer of human X-linked markers into murine somatic cells via isolated metaphase chromosomes. Proc Natl Acad Sci U S A (1978) 1.73
Phenotype stabilisation and integration of transferred material in chromosome-mediated gene transfer. Nature (1979) 1.73
Genetic analysis with man-mouse somatic cell hybrids. Linkage between human lactate dehydrogenase A and B and peptidase B. Nature (1970) 1.73
An efficient cis-element discovery method using multiple sequence comparisons based on evolutionary relationships. Genomics (2001) 1.72
Sequence analysis of the murine Hox-2.2, -2.3, and -2.4 homeo boxes: evolutionary and structural comparisons. Genomics (1987) 1.71
Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice. Proc Natl Acad Sci U S A (1989) 1.69
Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem Genet (1969) 1.69
Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteins. J Virol (1995) 1.68
Karyotype analysis utilizing differentially stained constitutive heterochromatin of human and murine chromosomes. Chromosoma (1971) 1.68
Cotransfer of thymidine kinase and galactokinase genes by chromosome-mediated gene transfer. Proc Natl Acad Sci U S A (1978) 1.67
lac repressor blocks in vivo transcription of lac control region DNA. Proc Natl Acad Sci U S A (1987) 1.66
Chromosome polymorphism in American Negro and White populations. Nature (1971) 1.66
The evolution of the vertebrate Dlx gene family. Proc Natl Acad Sci U S A (1996) 1.64
Chromosomal abnormalities in the human population: estimation of rates based on New Haven newborn study. Science (1970) 1.64
Biological detection of specific mRNA molecules by microinjection. Proc Natl Acad Sci U S A (1979) 1.63
Cloning and expression of murine lymphotoxin cDNA. J Immunol (1987) 1.62
Parasexual approaches to the genetics of man. Annu Rev Genet (1975) 1.62
Genetic complementation in heterokaryons of human fibroblasts defective in cobalamin metabolism. Proc Natl Acad Sci U S A (1975) 1.62
Expression of liver phenotypes in cultured mouse hepatoma cells. J Natl Cancer Inst (1980) 1.60
Pluripotent teratocarcinoma-thymus somatic cell hybrids. Cell (1976) 1.60
Mouse-human heterokaryon analysis with a 33258 Hoechst-Giemsa technique. J Cell Biol (1975) 1.59
Differential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant. J Virol (1990) 1.58
Embryonal carcinoma cells (and their somatic cell hybrids) are resistant to infection by the murine parvovirus MVM, which does infect other teratocarcinoma-derived cell lines. J Cell Physiol (1977) 1.58
Intracellular transport of herpes simplex virus gD occurs more rapidly in uninfected cells than in infected cells. J Virol (1985) 1.56
Detection of homeobox genes in development and evolution. Proc Natl Acad Sci U S A (1991) 1.55
Transactivation of a late herpes simplex virus promoter. Mol Cell Biol (1984) 1.53
Chromosomal assignment of a family of human oncogenes. Proc Natl Acad Sci U S A (1983) 1.53