Published in Proc Natl Acad Sci U S A on May 01, 1983
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Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys. J Virol (1991) 3.46
DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. EMBO J (1985) 3.20
Highly conserved sequences in the 3' untranslated region of mRNAs coding for homologous proteins in distantly related species. Nucleic Acids Res (1985) 2.83
Identification of a retrovirus-like repetitive element in human DNA. Proc Natl Acad Sci U S A (1984) 2.25
Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes. EMBO J (1984) 2.18
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Nucleotide sequence of the Adh gene region of Drosophila pseudoobscura: evolutionary change and evidence for an ancient gene duplication. Genetics (1987) 2.04
Nucleotide sequences of chimpanzee MHC class I alleles: evidence for trans-species mode of evolution. EMBO J (1988) 1.98
Molecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient. Proc Natl Acad Sci U S A (1984) 1.95
Potential basis for regulation of the coordinately expressed fibrinogen genes: homology in the 5' flanking regions. Proc Natl Acad Sci U S A (1984) 1.91
The subtelomeric Y' repeat family in Saccharomyces cerevisiae: an experimental system for repeated sequence evolution. Genetics (1990) 1.79
Exon shuffling in vivo can generate novel HLA class I molecules. EMBO J (1985) 1.54
Organization of the human myoglobin gene. EMBO J (1984) 1.49
Searching for coding sequences in the mammalian genome: the H-2K region of the mouse MHC is replete with genes expressed in embryos. EMBO J (1988) 1.43
The synonymous substitution rate of the major histocompatibility complex loci in primates. Proc Natl Acad Sci U S A (1993) 1.34
Structural organization of glycophorin A and B genes: glycophorin B gene evolved by homologous recombination at Alu repeat sequences. Proc Natl Acad Sci U S A (1989) 1.19
The Drosophila virilis dopa decarboxylase gene is developmentally regulated when integrated into Drosophila melanogaster. EMBO J (1986) 1.18
DNA sequence transfer between two high-cysteine chorion gene families in the silkmoth Bombyx mori. Proc Natl Acad Sci U S A (1984) 1.12
Gene conversion-like events cause steroid 21-hydroxylase deficiency in congenital adrenal hyperplasia. Proc Natl Acad Sci U S A (1987) 1.11
Mouse histocompatibility-related genes are not conserved in other mammals. EMBO J (1985) 1.09
Organization and structure of the Qa genes of the major histocompatibility complex of the C3H mouse: implications for Qa function and class I evolution. EMBO J (1989) 1.07
Transcription analysis, physical mapping, and molecular characterization of a nonclassical human leukocyte antigen class I gene. Mol Cell Biol (1990) 1.02
Electron microscopic heteroduplex mapping identifies regions of the engrailed locus that are conserved between Drosophila melanogaster and Drosophila virilis. Mol Cell Biol (1985) 1.02
Comparative studies of Drosophila Antennapedia genes. Genetics (1992) 1.01
A truncated immunoglobulin epsilon pseudogene is found in gorilla and man but not in chimpanzee. Proc Natl Acad Sci U S A (1985) 1.00
Interaction of selection and biased gene conversion in a multigene family. Proc Natl Acad Sci U S A (1985) 0.99
Evolution of major histocompatibility complex class II allelic diversity: direct descent in mice and humans. Proc Natl Acad Sci U S A (1992) 0.98
The molecular organization of the H-2K region of two t-haplotypes: implications for the evolution of genetic diversity. EMBO J (1987) 0.95
Microrecombinations generate sequence diversity in the murine major histocompatibility complex: analysis of the Kbm3, Kbm4, Kbm10, and Kbm11 mutants. Mol Cell Biol (1988) 0.94
Concerted evolution of the mouse immunoglobulin gamma chain genes. EMBO J (1984) 0.92
The homeotic gene spalt (sal) evolved during Drosophila speciation. Proc Natl Acad Sci U S A (1989) 0.92
Comparison of exon 5 sequences from 35 class I genes of the BALB/c mouse. J Exp Med (1989) 0.88
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Nucleotide sequence, evolution, and expression of the fetal globin gene of the spider monkey Ateles geoffroyi. Proc Natl Acad Sci U S A (1985) 0.84
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Ancestral major histocompatibility complex DRB genes beget conserved patterns of localized polymorphisms. Proc Natl Acad Sci U S A (1996) 0.80
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Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature (1979) 11.83
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The structure and evolution of the two nonallelic rat preproinsulin genes. Cell (1979) 9.25
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments. Cell (1980) 8.77
The nucleotide sequence of the human beta-globin gene. Cell (1980) 8.11
The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes. Cell (1979) 8.11
Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence. Science (1979) 6.94
Gene conversion: some implications for immunoglobulin genes. Cell (1981) 6.70
A kappa-immunoglobulin gene is formed by site-specific recombination without further somatic mutation. Nature (1979) 6.54
The complete sequence of a chromosomal mouse alpha--globin gene reveals elements conserved throughout vertebrate evolution. Cell (1979) 6.05
Sequence of the human insulin gene. Nature (1980) 5.76
A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell (1981) 5.43
Tissue-specific expression of mouse-alpha-amylase genes: nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland. Cell (1980) 5.25
Complete nucleotide sequence of mouse immunoglobulin mu gene and comparison with other immunoglobulin heavy chain genes. Nucleic Acids Res (1980) 5.20
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Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene. Cell (1979) 5.04
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Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes. Cell (1981) 4.95
Clustered arrangement of immunoglobulin lambda constant region genes in man. Nature (1981) 4.87
The major histocompatibility complex of the mouse. Science (1979) 4.76
Clusters of genes encoding mouse transplantation antigens. Cell (1982) 4.71
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The structures of cytochrome c and the rates of molecular evolution. J Mol Evol (1971) 4.37
Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. Nucleic Acids Res (1981) 4.03
The primary sequence of rabbit alpha-globin mRNA. Cell (1978) 3.88
Exon/intron organization and complete nucleotide sequence of an HLA gene. Proc Natl Acad Sci U S A (1982) 3.72
Molecular evolution of mRNA: a method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application. J Mol Evol (1980) 3.61
Evolution of human immunoglobulin kappa J region genes. J Biol Chem (1982) 3.41
DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen. Science (1982) 3.17
Construction and analysis of recombinant DNA for human chorionic somatomammotropin. Nature (1977) 3.13
Human immunoglobulin heavy chain genes: evolutionary comparisons of C mu, C delta and C gamma genes and associated switch sequences. Nucleic Acids Res (1981) 3.11
Allelic and nonallelic homology of a supergene family. Proc Natl Acad Sci U S A (1982) 2.72
Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer. Proc Natl Acad Sci U S A (1980) 2.68
DNA sequence of the rat growth hormone gene: location of the 5' terminus of the growth hormone mRNA and identification of an internal transposon-like element. Nucleic Acids Res (1981) 2.67
Molecular clock of silent substitution: at least six-fold preponderance of silent changes in mitochondrial genes over those in nuclear genes. J Mol Evol (1982) 2.58
Structure of cloned DNA complementary to rat prolactin messenger RNA. J Biol Chem (1980) 2.44
Isolation, cloning and sequence analysis of the cDNA for the alpha-subunit of human chorionic gonadotropin. Nature (1979) 2.36
Isolation of a cDNA clone for the murine transplantation antigen H-2Kb. Proc Natl Acad Sci U S A (1982) 2.20
Structure of a family of rat amylase genes. Nature (1980) 2.19
Human prolactin. cDNA structural analysis and evolutionary comparisons. J Biol Chem (1981) 2.19
The 3' untranslated regions of the duplicated human alpha-globin genes are unexpectedly divergent. Cell (1980) 2.08
Dual expression of lambda genes in the MOPC-315 plasmacytoma. Nature (1981) 2.03
Structure of C-terminal half of two H-2 antigens from cloned mRNA. Nature (1981) 1.90
Comparison of nucleotide sequences of mRNAs belonging to the mouse H-2 multigene family. Nucleic Acids Res (1982) 1.83
Allelic forms of rat kappa chain genes: evidence for strong selection at the level of nucleotide sequence. Proc Natl Acad Sci U S A (1981) 1.70
Nucleotide sequence of a human immunoglobulin C gamma 4 gene. DNA (1981) 1.56
An unusual evolutionary behaviour of a sea urchin histone gene cluster. EMBO J (1982) 1.48
The untranslated regions of beta-globin mRNA evolve at a functional rate in higher primates. Cell (1981) 1.35
Nucleotide sequence of the mRNA encoding the pre-alpha-subunit of mouse thyrotropin. Proc Natl Acad Sci U S A (1981) 1.23
Biochemical comparison of major histocompatibility complex molecules from different subspecies of Mus musculus: evidence for trans-specific evolution of alleles. Proc Natl Acad Sci U S A (1982) 1.21
Nucleotide sequence of constant and 3' untranslated regions of a kappa immunoglobulin light chain mRNA of a homozygous b4 rabbit. Proc Natl Acad Sci U S A (1981) 1.08
Recent divergence from a common ancestor of human IFN-alpha genes. Nature (1982) 1.04
Rat kappa-chain J-segment genes: two recent gene duplications separate rat and mouse. Cell (1982) 0.96
Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract (1995) 12.51
Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell (1988) 9.04
Evolutionary relationship of archaebacteria, eubacteria, and eukaryotes inferred from phylogenetic trees of duplicated genes. Proc Natl Acad Sci U S A (1989) 8.45
Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus. Nature (1983) 6.96
Total enteroscopy with a nonsurgical steerable double-balloon method. Gastrointest Endosc (2001) 6.76
Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell (1989) 6.11
Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's. Science (1989) 5.08
Nucleotide sequence divergence and functional constraint in mRNA evolution. Proc Natl Acad Sci U S A (1980) 4.71
Structural homology of Torpedo californica acetylcholine receptor subunits. Nature (1983) 4.70
A giant nucleopore protein that binds Ran/TC4. Nature (1995) 4.36
Two types of amino acid substitutions in protein evolution. J Mol Evol (1979) 4.34
Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell (1993) 4.04
Primary structure of alpha-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence. Nature (1982) 3.69
Male-driven molecular evolution: a model and nucleotide sequence analysis. Cold Spring Harb Symp Quant Biol (1987) 3.66
Molecular evolution of mRNA: a method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application. J Mol Evol (1980) 3.61
Nucleotide sequence of human endogenous retrovirus genome related to the mouse mammary tumor virus genome. J Virol (1986) 3.52
Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors. J Exp Med (1999) 3.07
Close structural resemblance between putative polymerase of a Drosophila transposable genetic element 17.6 and pol gene product of Moloney murine leukaemia virus. EMBO J (1985) 3.02
Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation. Genes Dev (1987) 2.86
Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes. Cell (1981) 2.84
The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron (1995) 2.82
Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell. Dev Biol (1996) 2.68
Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer. Proc Natl Acad Sci U S A (1980) 2.68
Successful en-bloc resection of large superficial tumors in the stomach and colon using sodium hyaluronate and small-caliber-tip transparent hood. Endoscopy (2003) 2.67
A role for Cajal-Retzius cells and reelin in the development of hippocampal connections. Nature (1997) 2.61
Molecular clock of silent substitution: at least six-fold preponderance of silent changes in mitochondrial genes over those in nuclear genes. J Mol Evol (1982) 2.58
The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. J Exp Med (1998) 2.56
Primary structures of beta- and delta-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences. Nature (1983) 2.55
Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells. Mol Cell Neurosci (2001) 2.47
Protein-bound acrolein: potential markers for oxidative stress. Proc Natl Acad Sci U S A (1998) 2.42
Cloning and sequence analysis of cDNA for the luminescent protein aequorin. Proc Natl Acad Sci U S A (1985) 2.42
Extraordinarily high evolutionary rate of pseudogenes: evidence for the presence of selective pressure against changes between synonymous codons. Proc Natl Acad Sci U S A (1981) 2.42
Evolution of RNA polymerases and branching patterns of the three major groups of Archaebacteria. J Mol Evol (1991) 2.38
The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse. J Biol Chem (1982) 2.37
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The complete nucleotide sequence of mouse immunoglobin gamma 2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer. Nucleic Acids Res (1981) 2.26
Nucleotide sequence of the staphylocoagulase gene: its unique COOH-terminal 8 tandem repeats. J Biochem (1987) 2.21
Nucleotide sequence of the Syrian hamster intracisternal A-particle gene: close evolutionary relationship of type A particle gene to types B and D oncovirus genes. J Virol (1985) 2.20
Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody. J Neurosci (1997) 2.17
Nucleotide sequence of the structural gene for colicin E1 and predicted structure of the protein. Proc Natl Acad Sci U S A (1982) 2.15
Structural organization of the human kininogen gene and a model for its evolution. J Biol Chem (1985) 2.14
Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure. J Biol Chem (1988) 2.09
Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res (2002) 2.06
Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes. J Biol Chem (1996) 2.01
Novel models for RNA splicing that involve a small nuclear RNA. Proc Natl Acad Sci U S A (1981) 2.00
Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress. J Biol Chem (2000) 1.98
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Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. Immunity (2000) 1.92
Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains. Proc Natl Acad Sci U S A (1982) 1.91
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response. J Biol Chem (2000) 1.89
The preferential codon usages in variable and constant regions of immunoglobulin genes are quite distinct from each other. Nucleic Acids Res (1979) 1.83
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Evolution of influenza virus genes. Mol Biol Evol (1985) 1.83
Potassium channels from NG108-15 neuroblastoma-glioma hybrid cells. Primary structure and functional expression from cDNAs. FEBS Lett (1989) 1.82
Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene. EMBO J (1994) 1.80
When overexpressed, a novel centrosomal protein, RanBPM, causes ectopic microtubule nucleation similar to gamma-tubulin. J Cell Biol (1998) 1.78
A retrospective study of intravascular ultrasound use in patients undergoing endovascular aneurysm repair: its usefulness and a description of the procedure. Eur J Vasc Endovasc Surg (2010) 1.77
The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells. J Neurosci (2000) 1.74
Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. Genomics (2001) 1.73
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy. J Clin Invest (1997) 1.73
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age. Invest Ophthalmol Vis Sci (1999) 1.67
Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model. Kidney Int (2007) 1.66
Surgical treatment and long-term outcome of renovascular hypertension in children and adolescents. Eur J Vasc Endovasc Surg (2010) 1.65
Newcastle disease virus evolution. II. Lack of gene recombination in generating virulent and avirulent strains. Virology (1989) 1.64
Effects of NXY-059 in experimental stroke: an individual animal meta-analysis. Br J Pharmacol (2009) 1.60
The amino acid sequence of the procoagulant- and prothrombin-binding domain isolated from staphylocoagulase. J Biol Chem (1986) 1.60
Structure and expression of the alkA gene of Escherichia coli involved in adaptive response to alkylating agents. J Biol Chem (1984) 1.59
Neurogenesis by progenitor cells in the ischemic adult rat hippocampus. Stroke (2001) 1.59
Crry, a complement regulatory protein, modulates renal interstitial disease induced by proteinuria. Kidney Int (1999) 1.57
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Newcastle disease virus evolution. I. Multiple lineages defined by sequence variability of the hemagglutinin-neuraminidase gene. Virology (1989) 1.55
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Secondary structure of MS2 phage RNA and bias in code word usage. Nucleic Acids Res (1979) 1.47
Early branchings in the evolution of eukaryotes: ancient divergence of entamoeba that lacks mitochondria revealed by protein sequence data. J Mol Evol (1993) 1.47
Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells. Kidney Int (2006) 1.46
Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif. Oncogene (1994) 1.46
Evolution and structure of two ADP-ribosylation enterotoxins, Escherichia coli heat-labile toxin and cholera toxin. FEBS Lett (1984) 1.45
Molecular cloning of the cDNA of human X chromosomal gene (CCG1) which complements the temperature-sensitive G1 mutants, tsBN462 and ts13, of the BHK cell line. EMBO J (1988) 1.45
How many biopsies should be performed during percutaneous transhepatic cholangioscopy to diagnose biliary tract cancer? Gastrointest Endosc (1999) 1.43
Long-term protective immunity of recipients of the OKA strain of live varicella vaccine. Pediatrics (1985) 1.43
Both RadA and RadB are involved in homologous recombination in Pyrococcus furiosus. J Biol Chem (2000) 1.42
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Primary structure and functional expression of the omega-conotoxin-sensitive N-type calcium channel from rabbit brain. Neuron (1993) 1.41
Collagen as a biomaterial. Annu Rev Biophys Bioeng (1974) 1.40
cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett (1994) 1.39
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Surgical treatment of patients with congenital vascular malformation-associated aneurysms. Eur J Vasc Endovasc Surg (2011) 1.38