PubRank

I W Mattaj

Author PubWeight™ 282.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CRM1 is an export receptor for leucine-rich nuclear export signals. Cell 1997 18.60
2 The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell 1995 9.98
3 Nucleocytoplasmic transport. Science 1996 8.76
4 Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding. Cell 1986 5.59
5 Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell 2001 5.33
6 The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J 1997 5.08
7 Nuclear export of different classes of RNA is mediated by specific factors. J Cell Biol 1994 4.99
8 Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins. Cell 1985 4.98
9 Monomethylated cap structures facilitate RNA export from the nucleus. Cell 1990 4.72
10 Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA. EMBO J 1989 4.69
11 Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B'' and their cognate RNAs. Nature 1990 4.67
12 A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell 1994 4.56
13 Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex. EMBO J 1997 4.06
14 A cap-binding protein complex mediating U snRNA export. Nature 1995 3.89
15 Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 1999 3.84
16 An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes. Nature 1985 3.80
17 Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences. Science 1995 3.79
18 Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nat Cell Biol 2001 3.67
19 Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs. EMBO J 1987 3.50
20 Identification of a nuclear export receptor for tRNA. Curr Biol 1998 3.49
21 U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell 1998 3.39
22 The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal. Cell 1990 3.24
23 In vitro assembly of U1 snRNPs. EMBO J 1987 3.18
24 RNA export. Cell 1995 3.03
25 Nucleocytoplasmic transport: the last 200 nanometers. Cell 1998 3.00
26 PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation. Cell 2000 2.88
27 A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export. J Cell Biol 1996 2.84
28 Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes. EMBO J 1983 2.81
29 A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export. J Cell Biol 1997 2.74
30 Importin provides a link between nuclear protein import and U snRNA export. Cell 1996 2.65
31 The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA. Cell 1993 2.58
32 The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein. Nat Struct Biol 2000 2.53
33 Nucleocytoplasmic transport: Ran, beta and beyond. Trends Cell Biol 2001 2.50
34 A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site. Genes Dev 1996 2.50
35 A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes. Nature 1987 2.48
36 Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif. Cell 1994 2.45
37 Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport. J Cell Biol 1991 2.45
38 The role of exportin-t in selective nuclear export of mature tRNAs. EMBO J 1998 2.40
39 RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase. Mol Cell Biol 1999 2.37
40 Participation of the nuclear cap binding complex in pre-mRNA 3' processing. Proc Natl Acad Sci U S A 1997 2.31
41 The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing. Genes Dev 2000 2.27
42 Functional analysis of mutant Xenopus U2 snRNAs. Cell 1989 2.23
43 GTP hydrolysis by Ran is required for nuclear envelope assembly. Mol Cell 2000 2.22
44 A cap binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAs. J Cell Biol 1992 2.20
45 Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway. EMBO J 2001 2.17
46 The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. EMBO J 2001 2.14
47 The U2B'' RNP motif as a site of protein-protein interaction. EMBO J 1990 2.12
48 Structure and sequence of the promoter area and of a 5' upstream demethylation site of the estrogen-regulated chicken vitellogenin ii gene. J Biol Chem 1983 2.11
49 Xenopus laevis U1 snRNA genes: characterisation of transcriptionally active genes reveals major and minor repeated gene families. EMBO J 1984 2.08
50 Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis. Curr Biol 1999 2.08
51 Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation. Genes Dev 1997 2.03
52 Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA. J Cell Biol 1992 2.01
53 Nuclear import of U snRNPs requires importin beta. EMBO J 1997 2.00
54 TFIID is required for in vitro transcription of the human U6 gene by RNA polymerase III. EMBO J 1991 1.97
55 Monospecific antibodies reveal details of U2 snRNP structure and interaction between U1 and U2 snRNPs. EMBO J 1986 1.96
56 Domains of U4 and U6 snRNAs required for snRNP assembly and splicing complementation in Xenopus oocytes. EMBO J 1990 1.96
57 Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol 2001 1.95
58 An abundant U6 snRNP found in germ cells and embryos of Xenopus laevis. EMBO J 1989 1.94
59 Loop I of U1 small nuclear RNA is the only essential RNA sequence for binding of specific U1 small nuclear ribonucleoprotein particle proteins. Mol Cell Biol 1988 1.77
60 Transport of RNA between nucleus and cytoplasm. Semin Cell Biol 1992 1.77
61 RNA-protein interactions. Cell 1991 1.71
62 The yeast nuclear cap binding complex can interact with translation factor eIF4G and mediate translation initiation. Mol Cell 2000 1.71
63 The determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non-identical. EMBO J 1993 1.67
64 RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus. J Cell Biol 1996 1.66
65 Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene. Proc Natl Acad Sci U S A 1982 1.63
66 Structure and expression of a Xenopus gene encoding an snRNP protein (U1 70K). EMBO J 1988 1.62
67 Functional characterization of X. laevis U5 snRNA genes. EMBO J 1987 1.62
68 A complex secondary structure in U1A pre-mRNA that binds two molecules of U1A protein is required for regulation of polyadenylation. EMBO J 1993 1.62
69 Roles of U4 and U6 snRNAs in the assembly of splicing complexes. EMBO J 1992 1.60
70 Multiple domains of U1 snRNA, including U1 specific protein binding sites, are required for splicing. EMBO J 1990 1.60
71 Nuclear retention of RNA as a mechanism for localization. RNA 1995 1.57
72 A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing. Nucleic Acids Res 1996 1.57
73 Genetic and physical interactions involving the yeast nuclear cap-binding complex. Mol Cell Biol 1999 1.56
74 A role for nucleoporin FG repeat domains in export of human immunodeficiency virus type 1 Rev protein and RNA from the nucleus. Mol Cell Biol 1996 1.55
75 Formation of the 3' end on U snRNAs requires at least three sequence elements. EMBO J 1986 1.52
76 RanBP3 influences interactions between CRM1 and its nuclear protein export substrates. EMBO Rep 2001 1.46
77 Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition. Genes Dev 1999 1.46
78 Ribonucleoprotein particles in cellular processes. J Cell Biol 1988 1.44
79 The Xenopus U2 gene PSE is a single, compact, element required for transcription initiation and 3' end formation. Nucleic Acids Res 1989 1.43
80 Conserved amino acid residues within and outside of the N-terminal ribonucleoprotein motif of U1A small nuclear ribonucleoprotein involved in U1 RNA binding. J Mol Biol 1991 1.40
81 Crystal structure of the human nuclear cap binding complex. Mol Cell 2001 1.32
82 The influence of 5' and 3' end structures on pre-mRNA metabolism. J Cell Sci Suppl 1995 1.32
83 Drosophila SNF/D25 combines the functions of the two snRNP proteins U1A and U2B' that are encoded separately in human, potato, and yeast. RNA 1996 1.31
84 Visualizing nuclear export of different classes of RNA by electron microscopy. RNA 1997 1.30
85 Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP. RNA 2000 1.30
86 Interaction between the human nuclear cap-binding protein complex and hnRNP F. Mol Cell Biol 1997 1.24
87 Conserved loop I of U5 small nuclear RNA is dispensable for both catalytic steps of pre-mRNA splicing in HeLa nuclear extracts. Mol Cell Biol 1999 1.24
88 Cofractionation of the TATA-binding protein with the RNA polymerase III transcription factor TFIIIB. Nucleic Acids Res 1992 1.23
89 RNA processing. Splicing in space. Nature 1995 1.22
90 Properties of a U1 RNA enhancer-like sequence. Nucleic Acids Res 1987 1.21
91 A weak interaction between the U2A' protein and U2 snRNA helps to stabilize their complex with the U2B" protein. Nucleic Acids Res 1991 1.21
92 Isolation and fine structure organisation of an avian vitellogenin gene coding for the major estrogen-inducible mRNA. Gene 1981 1.20
93 Analysis of in vitro binding of U1-A protein mutants to U1 snRNA. Nucleic Acids Res 1991 1.17
94 Cloning of nucleoplasmin from Xenopus laevis oocytes and analysis of its developmental expression. Genes Dev 1987 1.16
95 Anti-(U1) small nuclear RNA antibodies in anti-small nuclear ribonucleoprotein sera from patients with connective tissue diseases. J Clin Invest 1990 1.11
96 Common and unique transcription factor requirements of human U1 and U6 snRNA genes. EMBO J 1993 1.10
97 The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction. J Biol Chem 1999 1.06
98 Localisation of a strongly conserved section of coding sequence in glutamate dehydrogenase genes. FEBS Lett 1982 1.06
99 Proximal sequence element factor binding and species specificity in vertebrate U6 snRNA promoters. J Mol Biol 1992 1.05
100 Positionally exact initiation is required for the formation of a stable RNA polymerase II transcription complex in vivo. EMBO J 1988 1.05
101 Positive and negative functional interactions between promoter elements from different classes of RNA polymerase III-transcribed genes. EMBO J 1990 1.04
102 The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export. RNA 2001 1.03
103 An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B" spliceosome proteins. J Cell Biol 2000 1.02
104 The Xenopus laevis U2 gene distal sequence element (enhancer) is composed of four subdomains that can act independently and are partly functionally redundant. Mol Cell Biol 1989 1.02
105 Anti-OTF-1 antibodies inhibit NFIII stimulation of in vitro adenovirus DNA replication. Nucleic Acids Res 1989 1.00
106 Nuclear localization of a cap-binding protein complex. Cold Spring Harb Symp Quant Biol 1995 0.97
107 Recruiting proteins to the RNA world. Nat Struct Biol 1995 0.96
108 Only two of the four sites of interaction with nuclear factors within the Xenopus U2 gene promoter are necessary for efficient transcription. Nucleic Acids Res 1987 0.93
109 Mutant U2 snRNAs of Xenopus which can form an altered higher order RNA structure are unable to enter the nucleus. Exp Cell Res 1987 0.92
110 Nuclear exclusion of transcription factor IIIA and the 42s particle transfer RNA-binding protein in Xenopus oocytes: a possible mechanism for gene control? J Cell Biol 1983 0.91
111 Complex requirements for RNA polymerase III transcription of the Xenopus U6 promoter. Nucleic Acids Res 1990 0.90
112 A factor with Sp1 DNA-binding specificity stimulates Xenopus U6 snRNA in vivo transcription by RNA polymerase III. J Mol Biol 1992 0.90
113 The gdhA1 point mutation in Escherichia coli K12 CLR207 alters a key lysine residue of glutamate dehydrogenase. Mol Gen Genet 1993 0.89
114 Energy- and temperature-dependent in vitro export of RNA from synthetic nuclei. Biol Chem 1997 0.87
115 Nuclear transport of the U2 snRNP-specific U2B'' protein is mediated by both direct and indirect signalling mechanisms. J Cell Sci 1994 0.87
116 U snRNA gene families in Xenopus laevis. Oxf Surv Eukaryot Genes 1985 0.86
117 Meiosis: MeiRNA hits the spot. Curr Biol 1999 0.86
118 Cyclosporin A is a differential inhibitor of eukaryotic RNA polymerases. Exp Cell Res 1984 0.84
119 The Xenopus homeo boxes. Cold Spring Harb Symp Quant Biol 1985 0.82
120 Cell biology. Snail mail to the nucleus. Nature 1999 0.81
121 New pieces in the U5 puzzle. Curr Biol 1991 0.79
122 Cloning in a cosmid vector of complete 37 kb and 25 kb ribosomal DNA repeat units from the chicken. Biochim Biophys Acta 1982 0.79
123 Small nuclear RNA-protein complexes. Biochem Soc Trans 1988 0.78
124 Binding specificity determinants of U1A and U2B'' proteins. Mol Biol Rep 1990 0.78
125 Analysis of the in vitro binding of A and B" snRNP proteins to U1 and U2 snRNAs using mutated A and B" proteins. Mol Biol Rep 1990 0.77
126 Structure-function in Xenopus snRNPs. Mol Biol Rep 1990 0.76
127 Structural analysis of U small nuclear ribonucleoproteins by in vitro assembly. Methods Enzymol 1990 0.75
128 Nucleus and gene expression. Curr Opin Cell Biol 1997 0.75