Published in Cell on June 01, 1983
New human transforming genes detected by a tumorigenicity assay. Mol Cell Biol (1984) 3.43
Nucleotide sequence of cDNA clones of the murine myb proto-oncogene. EMBO J (1985) 2.73
Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol Cell Biol (1988) 2.70
Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene. Proc Natl Acad Sci U S A (1989) 2.59
Two modes of c-myb activation in virus-induced mouse myeloid tumors. Mol Cell Biol (1986) 2.57
Isolation of monoclonal antibodies specific for products of avian oncogene myb. Mol Cell Biol (1984) 2.50
Human c-myb protooncogene: nucleotide sequence of cDNA and organization of the genomic locus. Proc Natl Acad Sci U S A (1986) 2.47
The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J (1987) 2.35
Isolation of human cDNA clones of myb-related genes, A-myb and B-myb. Nucleic Acids Res (1988) 2.26
c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock. Mol Cell Biol (1988) 2.10
Characterization of the sequence-specific interaction of mouse c-myb protein with DNA. EMBO J (1990) 2.05
Murine myb protooncogene mRNA: cDNA sequence and evidence for 5' heterogeneity. Proc Natl Acad Sci U S A (1986) 2.05
Avian myeloblastosis virus and E26 virus oncogene products are nuclear proteins. Proc Natl Acad Sci U S A (1984) 1.97
Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors. EMBO J (1993) 1.97
Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells. Mol Cell Biol (1984) 1.92
Identification and preferential expression in thymic and bursal lymphocytes of a c-ets oncogene-encoded Mr 54,000 cytoplasmic protein. Proc Natl Acad Sci U S A (1986) 1.89
Subnuclear localization of proteins encoded by the oncogene v-myb and its cellular homolog c-myb. Mol Cell Biol (1986) 1.81
Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. Mol Cell Biol (1994) 1.81
Identification and characterization of the protein encoded by the human c-myb proto-oncogene. EMBO J (1986) 1.80
Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M. EMBO J (1996) 1.77
Structure of the protein encoded by the chicken proto-oncogene c-myb. Mol Cell Biol (1986) 1.69
Estrogen-dependent alterations in differentiation state of myeloid cells caused by a v-myb/estrogen receptor fusion protein. EMBO J (1991) 1.61
Rapid induction of B-cell lymphomas: insertional activation of c-myb by avian leukosis virus. J Virol (1988) 1.61
Antibodies to the evolutionarily conserved amino-terminal region of the v-myb-encoded protein detect the c-myb protein in widely divergent metazoan species. Proc Natl Acad Sci U S A (1986) 1.59
Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene. Mol Cell Biol (1991) 1.58
The proto-oncogene c-ets is preferentially expressed in lymphoid cells. Mol Cell Biol (1985) 1.53
A novel DNA binding protein with homology to Myb oncoproteins containing only one repeat can function as a transcriptional activator. EMBO J (1994) 1.50
Developmental regulation of c-myb in normal myeloid progenitor cells. Proc Natl Acad Sci U S A (1985) 1.49
Drosophila and vertebrate myb proteins share two conserved regions, one of which functions as a DNA-binding domain. EMBO J (1987) 1.48
Nuclear compartmentalization of the v-myb oncogene product. Mol Cell Biol (1985) 1.48
Structural organization and nucleotide sequence of mouse c-myb oncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5' coding sequences. Nucleic Acids Res (1986) 1.42
Activation of human raf transforming genes by deletion of normal amino-terminal coding sequences. Mol Cell Biol (1987) 1.39
Determination of the molecular weight of DNA-bound protein(s) responsible for gel electrophoretic mobility shift of linear DNA fragments examplified with purified viral myb protein. Nucleic Acids Res (1988) 1.39
Functional antagonism between members of the myb family: B-myb inhibits v-myb-induced gene activation. EMBO J (1992) 1.36
c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer. Mol Cell Biol (1995) 1.33
Activation of oncogenicity of the c-rel proto-oncogene. Mol Cell Biol (1986) 1.31
Multiple c-myb transcript cap sites are variously utilized in cells of mouse haemopoietic origin. EMBO J (1987) 1.31
D-type cyclins repress transcriptional activation by the v-Myb but not the c-Myb DNA-binding domain. EMBO J (1998) 1.26
Expression of enzymatically active poliovirus RNA-dependent RNA polymerase in Escherichia coli. Proc Natl Acad Sci U S A (1987) 1.24
Generation of altered transcripts by retroviral insertion within the c-myb gene in two murine monocytic leukemias. J Virol (1987) 1.24
Transformation by v-myb correlates with trans-activation of gene expression. Mol Cell Biol (1990) 1.23
Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation. J Virol (1988) 1.23
Transduction of c-myb into avian myeloblastosis virus: locating points of recombination within the cellular gene. J Virol (1983) 1.14
Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro. EMBO J (1989) 1.13
Interaction of C/EBPbeta and v-Myb is required for synergistic activation of the mim-1 gene. Mol Cell Biol (1996) 1.13
Expression of molecular clones of v-myb in avian and mammalian cells independently of transformation. J Virol (1986) 1.10
Induced differentiation of avian myeloblastosis virus-transformed myeloblasts: phenotypic alteration without altered expression of the viral oncogene. Mol Cell Biol (1984) 1.06
Murine myeloid cell lines derived by in vitro infection with recombinant c-myb retroviruses express myb from rearranged vector proviruses. EMBO J (1989) 1.02
A second c-myb protein is translated from an alternatively spliced mRNA expressed from normal and 5'-disrupted myb loci. Mol Cell Biol (1989) 0.98
tom-1, a novel v-Myb target gene expressed in AMV- and E26-transformed myelomonocytic cells. EMBO J (1997) 0.96
env-encoded residues are not required for transformation by p48v-myb. J Virol (1987) 0.96
DNA-binding activity associated with the v-myb oncogene product is not sufficient for transformation. J Virol (1988) 0.89
Overexpression of C-terminally but not N-terminally truncated Myb induces fibrosarcomas: a novel nonhematopoietic target cell for the myb oncogene. Mol Cell Biol (1994) 0.88
Transformation of Brown Leghorn chicken embryo fibroblasts by avian myeloblastosis virus proviral DNA. J Virol (1985) 0.87
Neoplastic transformation by E26 leukemia virus is mediated by a single protein containing domains of gag and myb genes. J Virol (1984) 0.86
Tumour immunogenicity, antigen presentation and immunological barriers in cancer immunotherapy. New J Sci (2014) 0.85
Coordinate regulation of myelomonocytic phenotype by v-myb and v-myc. Mol Cell Biol (1986) 0.85
v-myb does not prevent the expression of c-myb in avian erythroblasts. J Virol (1987) 0.84
Structural organization of upstream exons and distribution of transcription start sites in the chicken c-myb gene. Mol Cell Biol (1989) 0.84
Analysis of the v-myb structural components important for transactivation of gene expression. Nucleic Acids Res (1991) 0.83
Identification of an inducible regulator of c-myb expression during T-cell activation. Mol Cell Biol (1996) 0.83
Subnuclear associations of the v-myb oncogene product and actin are dependent on ionic strength during nuclear isolation. Mol Cell Biol (1987) 0.83
Myb-induced chromatin remodeling at a dual enhancer/promoter element involves non-coding rna transcription and is disrupted by oncogenic mutations of v-myb. J Biol Chem (2009) 0.82
Alternative splicing of RNAs transcribed from the human c-myb gene. Mol Cell Biol (1990) 0.82
Transcription and cancer. Br J Cancer (1991) 0.81
Protein product of proto-oncogene c-mil. Mol Cell Biol (1986) 0.81
Oncogenic point mutations in the Myb DNA-binding domain alter the DNA-binding properties of Myb at a physiological target gene. Nucleic Acids Res (2007) 0.79
The carboxyterminus of human c-myb protein stimulates activated transcription in trans. Nucleic Acids Res (1994) 0.78
Transformation-defective mutant of avian myeloblastosis virus that is temperature sensitive for production of transforming protein p45v-myb. Mol Cell Biol (1985) 0.78
Predicted common structural features of DNA-binding domains from Ets, Myb and HMG transcription factors. Nucleic Acids Res (1993) 0.78
Retroviral insertional activation of the c-myb proto-oncogene in a Marek's disease T-lymphoma cell line. J Virol (1996) 0.77
The glioma-amplified sequence 41 gene (GAS41) is a direct Myb target gene. Nucleic Acids Res (2004) 0.76
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol Cell Biol (1985) 25.52
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell (1978) 13.33
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein. Cell (1978) 11.17
Correct integration of retroviral DNA in vitro. Cell (1987) 10.73
Cellular oncogenes and retroviruses. Annu Rev Biochem (1983) 10.65
Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature (1983) 10.64
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (1984) 9.64
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas. Nature (1982) 9.12
A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev (1989) 8.80
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. Proc Natl Acad Sci U S A (1989) 8.13
Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell (1999) 8.03
The molecular genetics of cancer. Science (1987) 7.64
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proc Natl Acad Sci U S A (1979) 7.55
Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell (1978) 7.46
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules. J Virol (1980) 7.37
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
Continuous tissue culture cell lines derived from chemically induced tumors of Japanese quail. Cell (1977) 7.23
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc Natl Acad Sci U S A (1983) 7.01
Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state. Cell (1981) 6.98
Expression of human immune interferon cDNA in E. coli and monkey cells. Nature (1982) 6.55
Comparative biochemical properties of normal and activated human ras p21 protein. Nature (1984) 6.50
Virus-specific ribonucleic acid in cells producing rous sarcoma virus: detection and characterization. J Virol (1972) 6.38
Standardized and simplified nomenclature for proteins common to all retroviruses. J Virol (1988) 6.31
Biological properties of human c-Ha-ras1 genes mutated at codon 12. Nature (1984) 6.21
Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: the architecture of a transduced oncogene. Cell (1982) 6.19
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene. Nature (1983) 5.90
Viral myb oncogene encodes a sequence-specific DNA-binding activity. Nature (1988) 5.72
Transcripts from the cellular homologs of retroviral oncogenes: distribution among chicken tissues. Mol Cell Biol (1982) 5.70
Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol Cell Biol (1987) 5.67
Isolation and expression of an altered mouse dihydrofolate reductase cDNA. Proc Natl Acad Sci U S A (1983) 5.46
The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature (1987) 5.43
Retroviruses. Annu Rev Biochem (1978) 5.41
Initiation of translation at internal AUG codons in mammalian cells. Nature (1984) 5.34
The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses. Cell (1977) 5.23
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product. Nature (1980) 5.22
Viral oncogenes. Cell (1985) 5.20
Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev (1998) 5.14
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. J Mol Biol (1976) 5.07
The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane. Proc Natl Acad Sci U S A (1980) 4.99
Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature (1984) 4.99
Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J (1997) 4.99
The MYC protein activates transcription of the alpha-prothymosin gene. EMBO J (1991) 4.96
Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src). Proc Natl Acad Sci U S A (1981) 4.69
The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme. Science (1988) 4.69
Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature (1989) 4.65
The low molecular weight RNAs of Rous sarcoma virus. I. The 4 S RNA. Virology (1970) 4.64
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. Cell (1983) 4.53
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proc Natl Acad Sci U S A (1978) 4.47
c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature (2001) 4.46
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture. Nature (1985) 4.31
Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts. Proc Natl Acad Sci U S A (1973) 4.19
A joint produce of the genes gag and pol of avian sarcoma virus: a possible precursor of reverse transcriptase. Cell (1977) 4.18
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations. Nature (1983) 4.15
Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29. Nature (1983) 4.06
Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA. Cell (1977) 4.06
Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src). Proc Natl Acad Sci U S A (1981) 4.04
Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. J Mol Biol (1978) 4.04
The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine. J Biol Chem (1980) 3.95
Transcription of DNA from the 70S RNA of Rous sarcoma virus. I. Identification of a specific 4S RNA which serves as primer. J Virol (1974) 3.90
A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell (1990) 3.87
Identification of nuclear proteins encoded by viral and cellular myc oncogenes. Nature (1984) 3.86
Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements. Proc Natl Acad Sci U S A (1981) 3.82
Computer-based screening system for patients at risk of hypothyroidism. Lancet (1969) 3.70
DNA and RNA from uninfected vertebrate cells contain nucleotide sequences related to the putative transforming gene of avian myelocytomatosis virus. J Virol (1979) 3.68
Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids. Mol Cell Biol (1983) 3.63
Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus. Nature (1975) 3.63
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature (1983) 3.56
Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus. Cell (1982) 3.53
Purification and characterization of the deoxyribonucleic acid polymerase associated with Rous sarcoma virus. Biochemistry (1972) 3.53
Daily requirement of oxygen to reverse pulmonary hypertension in patients with chronic bronchitis. Br Med J (1972) 3.43
Corrections to the nucleotide sequence of the src gene of Rous sarcoma virus. Nature (1983) 3.42
Transduction of a cellular oncogene: the genesis of Rous sarcoma virus. Proc Natl Acad Sci U S A (1983) 3.41
Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: assay by molecular hybridization. Virology (1975) 3.40
A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein. Proc Natl Acad Sci U S A (1981) 3.32
RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with 70 S viral RNA as template. J Mol Biol (1973) 3.32
The protein encoded by the human proto-oncogene c-myc. Proc Natl Acad Sci U S A (1984) 3.31
Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA. Proc Natl Acad Sci U S A (1977) 3.31
Laparoscopic versus minilaparotomy cholecystectomy: a randomised trial. Lancet (1994) 3.29
Detection of avian tumor virus-specific nucleotide sequences in avian cell DNAs (reassociation kinetics-RNA tumor viruses-gas antigen-Rous sarcoma virus, chick cells). Proc Natl Acad Sci U S A (1972) 3.28
Transient excess of MYC activity can elicit genomic instability and tumorigenesis. Proc Natl Acad Sci U S A (1999) 3.24