Published in Proc Natl Acad Sci U S A on November 01, 1983
A membrane protein encoded by Epstein-Barr virus in latent growth-transforming infection. Proc Natl Acad Sci U S A (1984) 5.60
Strategies for achieving high-level expression of genes in Escherichia coli. Microbiol Rev (1996) 4.93
Nucleotide sequence of a yeast Ty element: evidence for an unusual mechanism of gene expression. Proc Natl Acad Sci U S A (1985) 4.93
Uses of lac fusions for the study of biological problems. Microbiol Rev (1985) 4.38
Immunofluorescence localization of the Saccharomyces cerevisiae CDC12 gene product to the vicinity of the 10-nm filaments in the mother-bud neck. Mol Cell Biol (1987) 3.70
A bicistronic Epstein-Barr virus mRNA encodes two nuclear proteins in latently infected, growth-transformed lymphocytes. J Virol (1987) 3.58
Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors. EMBO J (1985) 2.91
The replication initiator protein of plasmid pT181 has sequence-specific endonuclease and topoisomerase-like activities. Proc Natl Acad Sci U S A (1985) 2.59
RAD3 gene of Saccharomyces cerevisiae: nucleotide sequence of wild-type and mutant alleles, transcript mapping, and aspects of gene regulation. Mol Cell Biol (1985) 2.16
Characterization of a gene product (Sec53p) required for protein assembly in the yeast endoplasmic reticulum. J Cell Biol (1985) 1.97
Rapid purification of a cloned gene product by genetic fusion and site-specific proteolysis. Proc Natl Acad Sci U S A (1984) 1.97
Replication initiator protein of plasmid R6K autoregulates its own synthesis at the transcriptional step. Proc Natl Acad Sci U S A (1985) 1.63
Positive and negative roles of an initiator protein at an origin of replication. Proc Natl Acad Sci U S A (1986) 1.56
The cellular RNA-binding protein EAP recognizes a conserved stem-loop in the Epstein-Barr virus small RNA EBER 1. Mol Cell Biol (1993) 1.37
The replication initiator protein of plasmid pSC101 is a transcriptional repressor of its own cistron. Proc Natl Acad Sci U S A (1985) 1.35
Role of glutamic acid 177 of the ricin toxin A chain in enzymatic inactivation of ribosomes. Mol Cell Biol (1989) 1.29
An alkane-responsive expression system for the production of fine chemicals Appl Environ Microbiol (1999) 1.26
A contingent replication assay for the detection of protein-protein interactions in animal cells. Proc Natl Acad Sci U S A (1991) 1.19
Analysis of Agrobacterium tumefaciens plasmid pTiC58 replication region with a novel high-copy-number derivative. J Bacteriol (1985) 1.14
Sequence and expression of the Escherichia coli K1 neuC gene product. J Bacteriol (1992) 1.09
Temperature-sensitive mutations in the bacteriophage Mu c repressor locate a 63-amino-acid DNA-binding domain. J Bacteriol (1991) 1.07
Identification and characterization of the Myxococcus xanthus bsgA gene product. J Bacteriol (1988) 1.01
Repression of choline kinase by inositol and choline in Saccharomyces cerevisiae. J Bacteriol (1990) 0.91
Escherichia coli DnaX product, the tau subunit of DNA polymerase III, is a multifunctional protein with single-stranded DNA-dependent ATPase activity. Proc Natl Acad Sci U S A (1987) 0.89
Expression of the x-lor gene of human T-cell leukemia virus I in Escherichia coli. J Virol (1985) 0.81
Altered (copy-up) forms of initiator protein pi suppress the point mutations inactivating the gamma origin of plasmid R6K. J Bacteriol (1995) 0.79
Evaluation of the contingent replication assay (CRA) and its application to the study of the general transcription initiation factor, TFIIF. Nucleic Acids Res (1993) 0.75
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene (1982) 102.30
DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1. Biochem Biophys Res Commun (1970) 8.73
Trans-complementation-dependent replication of a low molecular weight origin fragment from plasmid R6K. Cell (1978) 8.28
Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit beta-globin. Cell (1980) 6.20
Lac repressor can be fused to beta-galactosidase. Nature (1974) 5.84
Circular R-factor molecules controlling penicillinase synthesis, replicating in Escherichia coli under either relaxed or stringent control. J Bacteriol (1970) 5.71
Molecular basis of beta-galactosidase alpha-complementation. Proc Natl Acad Sci U S A (1975) 4.38
Terminal stages of SV40 DNA replication proceed via multiply intertwined catenated dimers. Cell (1980) 4.32
The complete amino acid sequence of the Ca2+-dependent modulator protein (calmodulin) of bovine brain. J Biol Chem (1980) 3.38
A previously unidentified gene in the spc operon of Escherichia coli K12 specifies a component of the protein export machinery. Cell (1982) 2.84
Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system. J Biol Chem (1980) 2.63
The purification of beta-galactosidase from Escherichia coli by affinity chromatography. J Biol Chem (1971) 2.58
Interaction of the plasmid R6K-encoded replication initiator protein with its binding sites on DNA. Cell (1983) 2.48
Open reading frame cloning: identification, cloning, and expression of open reading frame DNA. Proc Natl Acad Sci U S A (1982) 2.39
Plasmid R6K DNA replication. I. Complete nucleotide sequence of an autonomously replicating segment. J Mol Biol (1982) 2.30
Exon cloning: immunoenzymatic identification of exons of the chicken lysozyme gene. Proc Natl Acad Sci U S A (1982) 2.07
The replication initiator protein of plasmid R6K tagged with beta-galactosidase shows sequence-specific DNA-binding. Cell (1983) 1.87
Requirement of a plasmid-encoded protein for replication in vitro of plasmid R6K. Proc Natl Acad Sci U S A (1978) 1.83
Characterization of an improved in vitro DNA replication system for Escherichia coli plasmids. Nucleic Acids Res (1979) 1.54
Three origins of replication are active in vivo in the R plasmid RSF1040. J Biol Chem (1980) 1.52
Activity in vitro of three replication origins of the antibiotic resistance plasmid RSF1040. J Biol Chem (1980) 1.45
Primary structure of the replication initiation protein of plasmid R6K. Proc Natl Acad Sci U S A (1982) 1.40
The nucleotide sequence of the replication origin beta of the plasmid R6K. J Biol Chem (1982) 1.08
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell (1999) 5.98
Studies on heterologous anti-lymphocyte serum in mice. I. In vitro and in vivo properties. J Immunol (1966) 5.59
Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes. Science (1991) 4.72
Studies on heterologous anti-lymphocyte serum in mice. II. Effect on the immune response. J Immunol (1966) 4.49
Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. Science (1992) 4.44
Purification of the centromere-specific protein CENP-A and demonstration that it is a distinctive histone. Proc Natl Acad Sci U S A (1991) 3.55
The E2 "gene" of bovine papillomavirus encodes an enhancer-binding protein. Proc Natl Acad Sci U S A (1987) 3.31
Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase. Biochemistry (1988) 3.23
The integration host factor of Escherichia coli binds to bent DNA at the origin of replication of the plasmid pSC101. Cell (1987) 3.06
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family. Proc Natl Acad Sci U S A (1989) 2.95
A calcium-dependent protein kinase with a regulatory domain similar to calmodulin. Science (1991) 2.74
Interaction of the plasmid R6K-encoded replication initiator protein with its binding sites on DNA. Cell (1983) 2.48
Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein. Cell (1988) 2.21
The prevention of infection in appendicectomy wounds. Br J Surg (1971) 2.11
The replication terminator protein of E. coli is a DNA sequence-specific contra-helicase. Cell (1989) 2.01
Purification of plant calmodulin by fluphenazine-Sepharose affinity chromatography. Biochem Biophys Res Commun (1979) 2.01
Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase. Proc Natl Acad Sci U S A (1985) 2.00
Rapid purification of a cloned gene product by genetic fusion and site-specific proteolysis. Proc Natl Acad Sci U S A (1984) 1.97
Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit. Mol Cell (2001) 1.88
Conformational changes in a replication origin induced by an initiator protein. Cell (1985) 1.87
The replication initiator protein of plasmid R6K tagged with beta-galactosidase shows sequence-specific DNA-binding. Cell (1983) 1.87
Characterization of the plant nicotinamide adenine dinucleotide kinase activator protein and its identification as calmodulin. Biochemistry (1980) 1.86
Primary structure of the essential replicon of the plasmid pSC101. Proc Natl Acad Sci U S A (1983) 1.80
DNA-protein interaction at the origin of DNA replication of the plasmid pSC101. Cell (1983) 1.78
NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-like site. J Immunol (1994) 1.78
Identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species. Proc Natl Acad Sci U S A (1986) 1.73
The nucleotide sequence surrounding the replication terminus of R6K. Proc Natl Acad Sci U S A (1981) 1.69
Determination of restriction sites and the nucleotide sequence surrounding the relaxation site of ColE1. J Mol Biol (1978) 1.67
Nucleotide sequence determination of a strong promoter of the colicin E 1 plasmid. Analysis of restriction sites protected by RNA polymerase interactions before and after limited transcription. Nucleic Acids Res (1979) 1.65
Replication initiator protein of plasmid R6K autoregulates its own synthesis at the transcriptional step. Proc Natl Acad Sci U S A (1985) 1.63
The activity of Cdc14p, an oligomeric dual specificity protein phosphatase from Saccharomyces cerevisiae, is required for cell cycle progression. J Biol Chem (1997) 1.54
The DNA-binding domain of HPV-16 E2 protein interaction with the viral enhancer: protein-induced DNA bending and role of the nonconserved core sequence in binding site affinity. Virology (1990) 1.53
Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells. Proc Natl Acad Sci U S A (1990) 1.52
Amino acid sequence of the calcium-dependent photoprotein aequorin. Biochemistry (1985) 1.49
DNA bending is induced in an enhancer by the DNA-binding domain of the bovine papillomavirus E2 protein. Proc Natl Acad Sci U S A (1988) 1.49
Osteogenesis imperfecta. The position of substitution for glycine by cysteine in the triple helical domain of the pro alpha 1(I) chains of type I collagen determines the clinical phenotype. J Clin Invest (1989) 1.45
Direct physical interaction between DnaG primase and DnaB helicase of Escherichia coli is necessary for optimal synthesis of primer RNA. Proc Natl Acad Sci U S A (1996) 1.43
Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5. J Biol Chem (1997) 1.42
Primary structure of the replication initiation protein of plasmid R6K. Proc Natl Acad Sci U S A (1982) 1.40
Activation of distant replication origins in vivo by DNA looping as revealed by a novel mutant form of an initiator protein defective in cooperativity at a distance. EMBO J (1992) 1.40
Medical research unit in a District General Hospital. Br Med J (1972) 1.39
Amino acid sequence of a mouse mucosal mast cell protease. Biochemistry (1989) 1.39
Heterogeneity, complexity, and repetition of the chloroplast DNA of Chlamydomonas reinhardtii. Proc Natl Acad Sci U S A (1971) 1.39
Protein tyrosine dephosphorylation and signal transduction. Trends Biochem Sci (1989) 1.37
The replication initiator protein of plasmid pSC101 is a transcriptional repressor of its own cistron. Proc Natl Acad Sci U S A (1985) 1.35
Cooperativity at a distance promoted by the combined action of two replication initiator proteins and a DNA bending protein at the replication origin of pSC101. Genes Dev (1991) 1.34
Termination of DNA replication of bacterial and plasmid chromosomes. Mol Microbiol (1999) 1.30
Cyanogen bromide digestion of the avian myeloblastosis virus pp19 protein: isolation of an amino-terminal peptide that binds to viral RNA. J Virol (1983) 1.27
The amino acid sequence of the sex steroid-binding protein of rabbit serum. J Biol Chem (1989) 1.22
The baculovirus Autographa californica encodes a protein tyrosine phosphatase. J Biol Chem (1993) 1.21
A host-encoded DNA-binding protein promotes termination of plasmid replication at a sequence-specific replication terminus. Proc Natl Acad Sci U S A (1989) 1.20
Termination of DNA replication in vitro at a sequence-specific replication terminus. Cell (1981) 1.19
Detection of DNA looping due to simultaneous interaction of a DNA-binding protein with two spatially separated binding sites on DNA. Proc Natl Acad Sci U S A (1988) 1.19
Characterization of the Net1 cell cycle-dependent regulator of the Cdc14 phosphatase from budding yeast. J Biol Chem (2001) 1.19
Mechanism of termination of DNA replication of Escherichia coli involves helicase-contrahelicase interaction. Proc Natl Acad Sci U S A (2001) 1.16
Crystal structure of the replication terminator protein from B. subtilis at 2.6 A. Cell (1995) 1.16
Plant and fungal calmodulin: Ca2+-dependent regulation of plant NAD kinase. Cell Calcium (1981) 1.15
DnaA protein is required for replication of the minimal replicon of the broad-host-range plasmid RK2 in Escherichia coli. J Bacteriol (1987) 1.14
Mechanistic studies of initiator-initiator interaction and replication initiation. EMBO J (1998) 1.13
Molecular cloning of the replication terminus of the plasmid R6K. Gene (1981) 1.12
The replication terminator protein of the gram-positive bacterium Bacillus subtilis functions as a polar contrahelicase in gram-negative Escherichia coli. Proc Natl Acad Sci U S A (1994) 1.12
The replication initiator protein pi of the plasmid R6K specifically interacts with the host-encoded helicase DnaB. Proc Natl Acad Sci U S A (1996) 1.12
The relationship between sequence-specific termination of DNA replication and transcription. EMBO J (1996) 1.11
The nucleotide sequence surrounding the origin of DNA replication of Col E1. Nucleic Acids Res (1977) 1.10
The tetratricopeptide repeat domain and a C-terminal region control the activity of Ser/Thr protein phosphatase 5. J Biol Chem (1999) 1.10
Direct photolabeling of the cGMP-stimulated cyclic nucleotide phosphodiesterase. J Biol Chem (1989) 1.10
Conformational changes induced by integration host factor at origin gamma of R6K and copy number control. J Biol Chem (1991) 1.09
A protein tyrosine phosphatase-like protein from baculovirus has RNA 5'-triphosphatase and diphosphatase activities. Proc Natl Acad Sci U S A (1998) 1.08
Escherichia coli replication terminator protein impedes simian virus 40 (SV40) DNA replication fork movement and SV40 large tumor antigen helicase activity in vitro at a prokaryotic terminus sequence. Proc Natl Acad Sci U S A (1991) 1.08
The nucleotide sequence of the replication origin beta of the plasmid R6K. J Biol Chem (1982) 1.08
Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells. Proc Natl Acad Sci U S A (1991) 1.08
Studies on the late replication of phage lambda: rolling-circle replication of the wild type and a partially suppressed strain, Oam29 Pam80. J Mol Biol (1975) 1.07
Mechanism of recruitment of DnaB helicase to the replication origin of the plasmid pSC101. Proc Natl Acad Sci U S A (1999) 1.07
A replication initiator protein enhances the rate of hybrid formation between a silencer RNA and an activator RNA. Cell (1987) 1.07
Replication of plasmid R6K origin gamma in vitro. Dependence on dual initiator proteins and inhibition by transcription. J Biol Chem (1991) 1.07
Human immunodeficiency virus infection and syncytium formation in HeLa cells expressing glycophospholipid-anchored CD4. J Virol (1991) 1.06
The contrahelicase activities of the replication terminator proteins of Escherichia coli and Bacillus subtilis are helicase-specific and impede both helicase translocation and authentic DNA unwinding. J Biol Chem (1995) 1.06
Mechanism of calcium induction of Renilla bioluminescence. Involvement of a calcium-triggered luciferin binding protein. Biochemistry (1974) 1.06
A replication origin is turned off by an origin-"silencer" sequence. Cell (1986) 1.05
Reproductive life of French-Canadians in the 17-18th centuries: a search for a trade-off between early fecundity and longevity. Exp Gerontol (1993) 1.04
Oesophageal hiatus hernia: long-term results of the conventional thoracic operation. Br J Surg (1967) 1.02
The noncatalytic C-terminal segment of the T cell protein tyrosine phosphatase regulates activity via an intramolecular mechanism. J Biol Chem (1997) 1.02
Mechanistic studies on the impact of transcription on sequence-specific termination of DNA replication and vice versa. J Biol Chem (1998) 1.02
Substitution of cysteine for glycine within the carboxyl-terminal telopeptide of the alpha 1 chain of type I collagen produces mild osteogenesis imperfecta. J Biol Chem (1988) 1.01
Isolation of an etiologic agent of acute respiratory disease (rhinotracheitis) of turkey poults. Avian Dis (1979) 1.01
Multiple pathways of copy control of gamma replicon of R6K: mechanisms both dependent on and independent of cooperativity of interaction of tau protein with DNA affect the copy number. Proc Natl Acad Sci U S A (1994) 1.01
Definitive emergency treatment of perforated duodenal ulcer. Surg Gynecol Obstet (1976) 1.00
Structural and functional analysis of a replication enhancer: separation of the enhancer activity from origin function by mutational dissection of the replication origin gamma of plasmid R6K. Proc Natl Acad Sci U S A (1992) 1.00
Purification of calmodulin by Ca2+-dependent affinity chromatography. Methods Enzymol (1983) 0.98
Sequence of terminal regions of cowpox virus DNA: arrangement of repeated and unique sequence elements. Proc Natl Acad Sci U S A (1982) 0.98
Cyclic AMP signaling pathways are important in IL-1 beta transcriptional regulation. J Immunol (1995) 0.98