Published in Proc Natl Acad Sci U S A on May 01, 1984
Brain region-specific decrease in the activity and expression of protein kinase A in the frontal cortex of regressive autism. PLoS One (2011) 0.83
Phorbol ester receptors and protein kinase C in primary neuronal cultures: development and stimulation of endogenous phosphorylation. J Cell Biol (1986) 0.80
Reduced activity of protein kinase C in the frontal cortex of subjects with regressive autism: relationship with developmental abnormalities. Int J Biol Sci (2012) 0.77
Expression of protein kinase C genes during ontogenic development of the central nervous system. Mol Cell Biol (1989) 0.76
α-Tocopherol and Hippocampal Neural Plasticity in Physiological and Pathological Conditions. Int J Mol Sci (2016) 0.75
Increased 19 kDa protein phosphorylation and protein kinase C activity in pressure-overload cardiac hypertrophy. Basic Res Cardiol (1992) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem (1982) 16.71
Phorbol diester receptor copurifies with protein kinase C. Proc Natl Acad Sci U S A (1983) 6.25
Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. J Biol Chem (1979) 4.12
Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties. J Biol Chem (1982) 3.64
Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters. J Biol Chem (1983) 3.60
Calcium-dependent protein kinase: widespread occurrence in various tissues and phyla of the animal kingdom and comparison of effects of phospholipid, calmodulin, and trifluoperazine. Proc Natl Acad Sci U S A (1980) 3.08
A role of calcium-activated phospholipid-dependent protein kinase in human platelet activation. Comparison of thrombin and collagen actions. J Biol Chem (1983) 2.02
Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase. J Biol Chem (1977) 1.94
Phospholipid-sensitive Ca2+-dependent protein kinase from heart. I. Purification and general properties. J Biol Chem (1982) 1.88
Phospholipid-sensitive Ca2+-dependent protein kinase from heart. II. Substrate specificity and inhibition by various agents. J Biol Chem (1982) 1.83
Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1976) 1.75
Molecular and cell isoforms during development. Science (1983) 1.37
Identification of a calcium- and phospholipid- dependent phorbol ester binding activity in the soluble fraction of mouse tissues. Biochem Biophys Res Commun (1983) 1.34
Stimulation by phosphatidylserine and calmodulin of calcium-dependent phosphorylation of endogenous proteins from cerebral cortex. J Biol Chem (1980) 1.32
Purification to homogeneity, characterization and monoclonal antibodies of phospholipid-sensitive Ca2+-dependent protein kinase from spleen. Biochem J (1983) 1.27
Phosphorylation of cardiac troponin inhibitory subunit (troponin I) and tropomyosin-binding subunit (troponin T) by cardiac phospholipid-sensitive Ca2+-dependent protein kinase. Biochem J (1983) 1.24
Changes in relative levels of guanosine-3':5'-monophosphate-dependent and adenosine-3':5'-monophosphate-dependent protein kinases in lung, heart, and brain of developing guinea pigs. Proc Natl Acad Sci U S A (1975) 1.16
Substrate proteins for calmodulin-sensitive and phospholipid-sensitive Ca2+-dependent protein kinases in heart, and inhibition of their phosphorylation by palmitoylcarnitine. Proc Natl Acad Sci U S A (1981) 1.06
Characterization of cytosolic calcium-activated phospholipid-dependent protein kinase activity in embryonal carcinoma cells. Effect of retinoc acid-induced differentiation of F9 cells to parietal endoderm. J Biol Chem (1983) 1.03
Inhibition by phenothiazine antipsychotic drugs of calcium-dependent phosphorylation of cerebral cortex proteins regulated by phospholipid or calmodulin. Life Sci (1981) 0.97
Basic protein in brain myelin is phosphorylated by endogenous phospholipid-sensitive Ca2+-dependent protein kinase. J Neurochem (1982) 0.96
Calmodulin-dependent protein phosphatase: a developmental study. Biochemistry (1983) 0.96
Phosphorylation of skeletal-muscle troponin I and troponin T by phospholipid-sensitive Ca2+-dependent protein kinase and its inhibition by troponin C and tropomyosin. Biochem J (1984) 0.86
Variation with embryonic development and regional localization of specific [3H]phorbol 12,13-dibutyrate binding to brain. Cancer Res (1981) 0.82
Ontogenetic aspects of phospholipid-sensitive calcium-dependent protein kinase in guinea pig tissues. Biochem Biophys Res Commun (1981) 0.80
Comparative abilities of lanthanide ions La3+ and Tb3+ to substitute for Ca2+ in regulating phospholipid-sensitive Ca2+-dependent protein kinase and myosin light chain kinase. Life Sci (1983) 0.77
Cyclic nucleotide-dependent protein kinases. IV. Widespread occurrence of adenosine 3',5'-monophosphate-dependent protein kinase in various tissues and phyla of the animal kingdom. Proc Natl Acad Sci U S A (1969) 6.02
Cyclic nucleotide-dependent protein kinases. 3. Purification and properties of adenosine 3',5'-monophosphate-dependent protein kinase from bovine brain. J Biol Chem (1969) 5.37
Treatment of advanced Parkinson's disease by posterior GPi pallidotomy: 1-year results of a pilot study. Ann Neurol (1996) 3.45
Role of the posterior parietal cortex in updating reaching movements to a visual target. Nat Neurosci (1999) 3.39
Calcium-dependent protein kinase: widespread occurrence in various tissues and phyla of the animal kingdom and comparison of effects of phospholipid, calmodulin, and trifluoperazine. Proc Natl Acad Sci U S A (1980) 3.08
Cyclic nucleotide-dependent protein kinases. VI. Isolation and partial purification of a protein kinase activated by guanosine 3',5'-monophosphate. J Biol Chem (1970) 2.89
An adenosine 3',5'-monophosphate-dependent protein kinase from Escherichia coli. J Biol Chem (1969) 2.86
Cyclic nucleotide-dependent protein kinases. X. An assay method for the measurement of quanosine 3',5'-monophosphate in various biological materials and a study of agents regulating its levels in heart and brain. J Biol Chem (1972) 2.35
Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways. J Biol Chem (1985) 2.24
Normalizing motor-related brain activity: subthalamic nucleus stimulation in Parkinson disease. Neurology (2006) 2.05
Spontaneous intracranial hypotension causing reversible frontotemporal dementia. Neurology (2002) 1.89
Phospholipid-sensitive Ca2+-dependent protein kinase from heart. I. Purification and general properties. J Biol Chem (1982) 1.88
Phospholipid-sensitive Ca2+-dependent protein kinase from heart. II. Substrate specificity and inhibition by various agents. J Biol Chem (1982) 1.83
Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting. J Biol Chem (1998) 1.83
N-terminal methionine-specific peptidase in Salmonella typhimurium. Proc Natl Acad Sci U S A (1987) 1.66
Role of muscarinic cholinergic receptors in regulation of guanosine 3':5'-cyclic monophosphate content in mammalian brain, heart muscle, and intestinal smooth muscle. Proc Natl Acad Sci U S A (1972) 1.66
Phospholipid-sensitive calcium-dependent protein kinase: inhibition by antipsychotic drugs. Biochem Biophys Res Commun (1981) 1.65
Cardiac troponin I mutants. Phosphorylation by protein kinases C and A and regulation of Ca(2+)-stimulated MgATPase of reconstituted actomyosin S-1. J Biol Chem (1995) 1.64
Adenosine 3',5'-monophosphate-dependent protein kinase from brain. Science (1968) 1.64
A comparison of the effects of lipolytic and antilipolytic agents on adenosine 3',5'-monophosphate levels in adipose cells as determined by prior labeling with adenine-8-14C. J Biol Chem (1969) 1.56
Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament properties. J Biol Chem (1996) 1.49
Adenylate cyclase in islets of Langerhans. Isolation of islets and regulation of adenylate cyclase activity by various hormones and agents. J Biol Chem (1973) 1.45
The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. J Biol Chem (1998) 1.45
Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides. Proc Natl Acad Sci U S A (1993) 1.42
Regulation of protein kinase C by lysophospholipids. Potential role in signal transduction. J Biol Chem (1988) 1.38
Polymyxin B is a more selective inhibitor for phospholipid-sensitive Ca2+-dependent protein kinase than for calmodulin-sensitive Ca2+-dependent protein kinase. Biochem Biophys Res Commun (1982) 1.37
Protein kinases 1988: a current perspective. FASEB J (1988) 1.36
Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by protein kinase C and comparative substrate activity of synthetic peptides containing the phosphorylation sites. J Biol Chem (1989) 1.34
Stimulation by phosphatidylserine and calmodulin of calcium-dependent phosphorylation of endogenous proteins from cerebral cortex. J Biol Chem (1980) 1.32
Purification to homogeneity, characterization and monoclonal antibodies of phospholipid-sensitive Ca2+-dependent protein kinase from spleen. Biochem J (1983) 1.27
Protein kinase C in fibroblasts. Characteristics of its intracellular location during growth and after exposure to phorbol esters and other mitogens. J Biol Chem (1987) 1.27
Protein kinase C-mediated phosphorylation of troponin I and C-protein in isolated myocardial cells is associated with inhibition of myofibrillar actomyosin MgATPase. J Biol Chem (1993) 1.26
Guanosine 3':5'-monophosphate-dependent protein kinases in mammalian tissues. Proc Natl Acad Sci U S A (1974) 1.24
Role of protein kinase C in the phosphorylation of cardiac myosin light chain 2. Biochem J (1993) 1.24
Phosphorylation of cardiac troponin inhibitory subunit (troponin I) and tropomyosin-binding subunit (troponin T) by cardiac phospholipid-sensitive Ca2+-dependent protein kinase. Biochem J (1983) 1.24
Cyclic nucleotide-dependent protein kinases. V. Preparation and properties of adenosine 3',5'-monophosphate-dependent protein kinase from various bovine tissues. Biochim Biophys Acta (1970) 1.23
Molecular analysis of the X11-mLin-2/CASK complex in brain. J Neurosci (1999) 1.22
Protein kinase C phosphorylation of cardiac troponin I or troponin T inhibits Ca2(+)-stimulated actomyosin MgATPase activity. J Biol Chem (1991) 1.22
X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion. J Biol Chem (1998) 1.21
Differential regulation of cardiac actomyosin S-1 MgATPase by protein kinase C isozyme-specific phosphorylation of specific sites in cardiac troponin I and its phosphorylation site mutants. Biochemistry (1996) 1.20
Insulin-like activity of a microbial protease on isolated fat cells. Arch Biochem Biophys (1966) 1.19
Regulation of myocardial cyclic AMP by isoproterenol, glucagon and acetylcholine. Biochem Biophys Res Commun (1971) 1.18
Cyclic nucleotide-dependent protein kinases. 8. An assay method for the measurement of adenosine 3',5'-monophosphate in various tissues and a study of agents influencing its level in adipose cells. J Biol Chem (1970) 1.16
Changes in relative levels of guanosine-3':5'-monophosphate-dependent and adenosine-3':5'-monophosphate-dependent protein kinases in lung, heart, and brain of developing guinea pigs. Proc Natl Acad Sci U S A (1975) 1.16
The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion. J Biol Chem (1998) 1.16
Phospholipid-sensitive Ca2+-dependent protein kinase and its substrates in human neutrophils. Biochem Biophys Res Commun (1983) 1.15
Polyclonal antibodies to phospholipid/Ca2+-dependent protein kinase and immunocytochemical localization of the enzyme in rat brain. Proc Natl Acad Sci U S A (1985) 1.13
Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Neuroscience (2010) 1.11
Dissociation and activation of adenosine 3',5'-monophosphate-dependent and guanosine 3',5'-monophosphate-dependent protein kinases by cyclic nucleotides and by substrate proteins. J Biol Chem (1973) 1.10
An assay method for cyclic AMP and cyclic GMP based upon their abilities to activate cyclic AMP-dependent and cyclic GMP-dependent protein kinases. Adv Cyclic Nucleotide Res (1972) 1.09
Involvement of a carbohydrate group in the active site for surface guided reassociation of animal cells. Nature (1973) 1.09
Polyamines inhibit phospholipid-sensitive and calmodulin-sensitive Ca2+-dependent protein kinases. Biochem J (1983) 1.08
Temporal changes in intracellular distribution of protein kinase C during differentiation of human leukemia HL60 cells induced by phorbol ester. FEBS Lett (1988) 1.07
Identification of specific sites in human P-glycoprotein phosphorylated by protein kinase C. J Biol Chem (1993) 1.07
Substrate proteins for calmodulin-sensitive and phospholipid-sensitive Ca2+-dependent protein kinases in heart, and inhibition of their phosphorylation by palmitoylcarnitine. Proc Natl Acad Sci U S A (1981) 1.06
On-line motor control in patients with Parkinson's disease. Brain (2004) 1.05
Effect of tamoxifen, a nonsteroidal antiestrogen, on phospholipid/calcium-dependent protein kinase and phosphorylation of its endogenous substrate proteins from the rat brain and ovary. Biochem Pharmacol (1985) 1.05
Testing basal ganglia motor functions through reversible inactivations in the posterior internal globus pallidus. J Neurophysiol (2007) 1.05
Large scale transient expression with COS cells. Cytotechnology (1995) 1.05
Purification and characterization of guanosine 3':5'-monophosphate-specific phosphodiesterase from guinea pig lung. J Biol Chem (1977) 1.04
Immunological quantitation of phospholipid/Ca2+-dependent protein kinase and its fragments. Tissue levels, subcellular distribution, and ontogenetic changes in brain and heart. J Biol Chem (1986) 1.03
Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains. J Biol Chem (2000) 1.03
Inhibition of protein kinase C by defensins, antibiotic peptides from human neutrophils. Biochem Pharmacol (1988) 1.02
The basal ganglia network mediates the planning of movement amplitude. Eur J Neurosci (2004) 1.02
Isoproterenol-induced cardiac hypertrophy: modifications in characteristics of beta-adrenergic receptor, adenylate cyclase, and ventricular contraction. Endocrinology (1979) 1.01
Cobra polypeptide cytotoxin I and marine worm polypeptide cytotoxin A-IV are potent and selective inhibitors of phospholipid-sensitive Ca2+-dependent protein kinase. FEBS Lett (1983) 1.01
Phospholipid-sensitive Ca2+-dependent protein kinase: a major protein phosphorylation system. Mol Cell Endocrinol (1984) 1.01
Calcium regulation of ciliary activity in rabbit tracheal epithelial explants and outgrowth. Eur J Cell Biol (1986) 1.00