Published in EMBO J on August 01, 1984
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An upstream enhancer and a negative element in the 5' flanking region of the human urokinase plasminogen activator gene. Nucleic Acids Res (1988) 1.13
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Antibodies to plasminogen activator inhibit human tumor metastasis. Cell (1983) 2.82
Purification and characterization of the plasminogen activator secreted by human melanoma cells in culture. J Biol Chem (1981) 2.80
Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells. Cell (1980) 2.76
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The primary structure of high molecular mass urokinase from human urine. The complete amino acid sequence of the A chain. Hoppe Seylers Z Physiol Chem (1982) 2.14
A proenzyme form of human urokinase. J Biol Chem (1982) 1.98
Hormonal regulation of plasminogen activator mRNA production in porcine kidney cells. Cell (1983) 1.76
The complete amino acid sequence of low molecular mass urokinase from human urine. Hoppe Seylers Z Physiol Chem (1982) 1.64
The production of distinct forms of plasminogen activator by mouse embryonic cells. Dev Biol (1982) 1.48
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Experimental model for quantitative study of metastasis. Cancer Res (1980) 1.32
Plasminogen activator released as inactive proenzyme from murine cells transformed by sarcoma virus. Eur J Biochem (1982) 1.21
Plasminogen activator secretion of human tumors in short-term organ culture, including a comparison of primary and metastatic colon tumors. Cancer Res (1983) 1.07
Effects of acidified fetal bovine serum on the fibrinolytic activity and growth of cells in culture. J Cell Physiol (1978) 1.06
Purification and characterization of a plasminogen activator from mouse cells transformed by an oncogenic virus. Biochim Biophys Acta (1980) 0.99
Phorbol ester and mitogens stimulate human fibroblast secretions of plasmin-activatable plasminogen activator and protease nexin, an antiactivator/antiplasmin. J Cell Biol (1983) 0.98
Modulation and mapping of a human plasminogen activator by cell fusion. Cell (1978) 0.98
Inhibition of a plasminogen activator from oncogenic virus-transformed mouse cells by rabbit antibodies against the enzyme. Biochim Biophys Acta (1980) 0.96
Complex-formation and inhibition of urokinase by blood plasma proteins. Biochem J (1983) 0.95
Effects of 12-O-tetradecanoylphorbol 13-acetate on the production of mRNAs for human tissue-type plasminogen activator. Eur J Biochem (1983) 0.94
Plasminogen activator from cells transformed by an oncogenic virus: inhibitors of the activation reaction. Biochim Biophys Acta (1979) 0.92
Effects of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate on newly synthesized proteins in mouse epidermis. Cell (1981) 0.92
Microinjected Xenopus oocytes synthesize active human plasminogen activator. Nucleic Acids Res (1981) 0.91
Specificity of response in hamster cells induced to produce plasminogen activator by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate. Cancer Res (1978) 0.90
Tumor promoters increase the synthesis of a 32,000-dalton protein in BALB/c 3T3 cells. Proc Natl Acad Sci U S A (1982) 0.89
Tumor-promoting phorbol esters affect production of prolactin and growth hormone by rat pituitary cells. Endocrinology (1981) 0.85
Effects of cholera toxin and actinomycin on synthesis of [35s]methionine-labeled proteins during progesterone-induced maturation of Xenopus laevis oocytes. Dev Biol (1982) 0.83
Regulation of gene expression by tumor promoters. III. Complementation of the developmental program in myeloid leukemic cells by regulating mRNA production and mRNA translation. Int J Cancer (1981) 0.83
Regulation of plasminogen activator in 3T3 cells: effect of phorbol myristate acetate on subcellular distribution and molecular weight. J Cell Biol (1981) 0.83
Two independent aspects of tumor promotion. Biochim Biophys Acta (1981) 0.79
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J Bacteriol (1995) 46.37
A pSC101-derived plasmid which shows no sequence homology to other commonly used cloning vectors. Gene (1984) 9.45
Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors. J Exp Med (1986) 5.09
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A pathway for disulfide bond formation in vivo. Proc Natl Acad Sci U S A (1993) 3.86
A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase. J Cell Biol (1985) 3.62
Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci U S A (1986) 3.42
Macrophage plasminogen activator: modulation of enzyme production by anti-inflammatory steroids, mitotic inhibitors, and cyclic nucleotides. Cell (1976) 3.13
An in vivo pathway for disulfide bond isomerization in Escherichia coli. Proc Natl Acad Sci U S A (1996) 2.98
Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. Genes Dev (1997) 2.96
Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages. J Exp Med (1984) 2.78
Mutations that allow disulfide bond formation in the cytoplasm of Escherichia coli. Science (1993) 2.73
Direct identification of prohormone conversion site in insulin-secreting cells. Cell (1985) 2.64
Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors. J Cell Biol (1987) 2.63
Secretion of plasminogen activator by human polymorphonuclear leukocytes. Modulation by glucocorticoids and other effectors. J Exp Med (1977) 2.60
Macrophage plasminogen activator: induction by concanavalin A and phorbol myristate acetate. Cell (1977) 2.47
The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. J Cell Biol (1990) 2.36
Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles. Cell (1987) 2.33
Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development (1991) 2.28
Temperature-sensitive mutation in the initiation codon of the rIIB gene of bacteriophage T4. Proc Natl Acad Sci U S A (1979) 2.18
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature (1995) 2.15
Cloning, nucleotide sequencing and expression of cDNAs encoding mouse urokinase-type plasminogen activator. Eur J Biochem (1985) 2.14
Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles. J Cell Biol (1986) 2.06
Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro. J Cell Biol (1990) 2.00
Macrophage plasminogen activator: induction by products of activated lymphoid cells. J Exp Med (1977) 2.00
A clathrin-coated, Golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin. Cell (1984) 1.99
Extracellular proteolysis in the adult murine brain. J Clin Invest (1993) 1.96
Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes. Genes Dev (1989) 1.95
Characterization of the cellular binding site for the urokinase-type plasminogen activator. J Biol Chem (1989) 1.93
Plasminogen activators in tissue remodeling and invasion: mRNA localization in mouse ovaries and implanting embryos. J Cell Biol (1989) 1.88
Transient translational silencing by reversible mRNA deadenylation. Cell (1992) 1.88
Expression of the endogenous type II secretion pathway in Escherichia coli leads to chitinase secretion. EMBO J (2000) 1.82
Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA. Genes Dev (1987) 1.74
Amiloride selectively inhibits the urokinase-type plasminogen activator. FEBS Lett (1987) 1.66
Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice. EMBO J (1999) 1.66
Antisense RNA directed against the 3' noncoding region prevents dormant mRNA activation in mouse oocytes. Science (1988) 1.63
Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids. J Exp Med (1976) 1.60
Specific protease deficiency in polymorphonuclear leukocytes of Chédiak-Higashi syndrome and beige mice. J Exp Med (1978) 1.60
Sites of synthesis of urokinase and tissue-type plasminogen activators in the murine kidney. J Clin Invest (1991) 1.59
Purification of murine T cell growth factor. A lymphocyte mitogen with helper activity. J Exp Med (1981) 1.57
Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery. Circ Res (1990) 1.54
TGF-beta 1 influences the relative development of the exocrine and endocrine pancreas in vitro. Development (1994) 1.51
The production of distinct forms of plasminogen activator by mouse embryonic cells. Dev Biol (1982) 1.48
Processing of unstable bacteriophage T4 gene 32 mRNAs into a stable species requires Escherichia coli ribonuclease E. EMBO J (1988) 1.47
Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med (1992) 1.46
Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis. Exp Cell Res (1993) 1.45
Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes. Proc Natl Acad Sci U S A (1994) 1.43
Facultative polypeptide translocation allows a single mRNA to encode the secreted and cytosolic forms of plasminogen activators inhibitor 2. EMBO J (1989) 1.38
Modulations of functional activity in differentiated macrophages are accompanied by early and transient increase or decrease in c-fos gene transcription. J Immunol (1987) 1.38
Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells. J Cell Biol (1987) 1.35
Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells. J Biol Chem (1995) 1.34
Growth-dependent synthesis of c-myc-encoded proteins: early stimulation by serum factors in synchronized mouse 3T3 cells. Mol Cell Biol (1985) 1.34
Plasminogen activator and mouse spermatozoa: urokinase synthesis in the male genital tract and binding of the enzyme to the sperm cell surface. J Cell Biol (1987) 1.33
Purification and characterization of a plasminogen activator inhibitor from the histiocytic lymphoma cell line U-937. J Biol Chem (1986) 1.33
Actin isoform synthesis and mRNA levels in quiescent and proliferating rat aortic smooth muscle cells in vivo and in vitro. Lab Invest (1986) 1.33
Plasminogen activators and their inhibitors in a human mammary cell line (HBL-100). Modulation by glucocorticoids. J Biol Chem (1986) 1.32
RNA and protein synthesis in human peripheral blood polymorphonuclear leukocytes. J Exp Med (1979) 1.30
Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas. Cancer Res (1987) 1.29
Plasminogen activator in mouse and rat oocytes: induction during meiotic maturation. Cell (1985) 1.29
Gastric M1 mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene. Int J Cancer (1998) 1.28
Masking, unmasking, and regulated polyadenylation cooperate in the translational control of a dormant mRNA in mouse oocytes. Genes Dev (1998) 1.26
Plasminogen activator inhibitor-1 in acute hyperoxic mouse lung injury. J Clin Invest (1996) 1.25
Plasminogen activator-specific inhibitors produced by human monocytes/macrophages. J Exp Med (1987) 1.24
Steroid-induced meiotic division in Xenopus laevis oocytes: surface and calcium. Nature (1978) 1.24
TGF-beta 1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-alpha, triggers insulin-dependent diabetes. Biochem Biophys Res Commun (1995) 1.23
c-fos gene transcription in murine macrophages is modulated by a calcium-dependent block to elongation in intron 1. Mol Cell Biol (1991) 1.20
A two-step recognition of signal sequences determines the translocation efficiency of proteins. EMBO J (1996) 1.19
Upregulation of urokinase receptor expression on migrating endothelial cells. J Cell Biol (1993) 1.18
Plasminogen activator of islets of Langerhans: modulation by glucose and correlation with insulin production. Proc Natl Acad Sci U S A (1980) 1.14
Phorbol ester induces cultured endothelial cells to invade a fibrin matrix in the presence of fibrinolytic inhibitors. J Cell Physiol (1987) 1.13
C-myc expression is dissociated from DNA synthesis and cell division in Xenopus oocyte and early embryonic development. EMBO J (1986) 1.13
Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis. EMBO J (2000) 1.11
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Differential protease expression by cutaneous squamous and basal cell carcinomas. J Clin Invest (1991) 1.09
Regulation of the expression of bacteriophage T4 genes 32 and 43. Virology (1977) 1.08