Published in Methods Enzymol on January 01, 1982
The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line. J Cell Biol (1988) 3.86
Architecture of the sarcomere matrix of skeletal muscle: immunoelectron microscopic evidence that suggests a set of parallel inextensible nebulin filaments anchored at the Z line. J Cell Biol (1988) 2.35
Titin is an extraordinarily long, flexible, and slender myofibrillar protein. Proc Natl Acad Sci U S A (1984) 1.63
Characterization of components of Z-bands in the fibrillar flight muscle of Drosophila melanogaster. J Cell Biol (1989) 1.45
Immunocytochemical studies of cardiac myofibrillogenesis in early chick embryos. I. Presence of immunofluorescent titin spots in premyofibril stages. J Cell Biol (1987) 1.36
Monoclonal antibodies distinguish titins from heart and skeletal muscle. J Cell Biol (1986) 1.32
Nebulin, a helical actin binding protein. EMBO J (1994) 1.31
Drosophila has a twitchin/titin-related gene that appears to encode projectin. Proc Natl Acad Sci U S A (1991) 1.24
Biosynthesis of titin in cultured skeletal muscle cells. J Cell Biol (1989) 1.05
Zeugmatin: a new high molecular weight protein associated with Z lines in adult and early embryonic striated muscle. J Cell Biol (1985) 1.00
Patients with myasthenia gravis and thymoma have in their sera IgG autoantibodies against titin. Clin Exp Immunol (1990) 0.94
Muscle fibre breakdown in venom-induced muscle degeneration. J Anat (2003) 0.91
Subsarcomeric distribution of calcium in demembranated fibers of rabbit psoas muscle. Biophys J (1993) 0.90
Nebulin (NEB) mutations in a childhood onset distal myopathy with rods and cores uncovered by next generation sequencing. Eur J Hum Genet (2013) 0.90
Formation of ATP-insensitive weakly-binding crossbridges in single rabbit psoas fibers by treatment with phenylmaleimide or para-phenylenedimaleimide. Biophys J (1992) 0.88
X-ray diffraction evidence for the existence of 102.0- and 230.0-nm transverse periodicities in striated muscle. J Cell Biol (1987) 0.86
Identification and characterization of two huge protein components of the brush border cytoskeleton: evidence for a cellular isoform of titin. J Cell Biol (1992) 0.84
Isolation of nebulin from rabbit skeletal muscle and its interaction with actin. J Biomed Biotechnol (2010) 0.80
Giant FAZ10 is required for flagellum attachment zone stabilization and furrow positioning in Trypanosoma brucei. J Cell Sci (2017) 0.75
Cardiac myosin phenotype remodelling following adrenodemedullectomy and chronic 6-hydroxydopamine in male Sprague-Dawley rats. Exp Clin Cardiol (2003) 0.75
Nuances of electrophoresis study of titin/connectin. Biophys Rev (2017) 0.75
Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science (1995) 8.31
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature (1999) 6.37
Sequence and genomic organization of Norwalk virus. Virology (1993) 6.25
Pairwise end sequencing: a unified approach to genomic mapping and sequencing. Genomics (1995) 4.83
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem (1999) 4.56
Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells. Proc Natl Acad Sci U S A (1975) 4.38
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci U S A (1995) 4.22
Right 25 bp terminus sequence of the nopaline T-DNA is essential for and determines direction of DNA transfer from agrobacterium to the plant genome. Cell (1984) 4.09
A mini binary vector series for plant transformation. Plant Mol Biol (1999) 3.75
Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene (2009) 3.64
Intracellular distributions of mechanochemical proteins in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 3.63
Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Res (1998) 3.44
Titin: major myofibrillar components of striated muscle. Proc Natl Acad Sci U S A (1979) 2.96
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol (1999) 2.92
An approach to nearest neighbor analysis of membrane proteins. Application to the human erythrocyte membrane of a method employing cleavable cross-linkages. J Biol Chem (1974) 2.53
Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Anal Biochem (2000) 2.53
Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers. Anal Chem (2001) 2.42
naked cuticle encodes an inducible antagonist of Wnt signalling. Nature (2000) 2.35
Sarcomere-associated cytoskeletal lattices in striated muscle. Review and hypothesis. Cell Muscle Motil (1985) 2.30
Site-Specific Nick in the T-DNA Border Sequence as a Result of Agrobacterium vir Gene Expression. Science (1987) 2.26
Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs. Lett Appl Microbiol (2008) 2.19
A network of transverse and longitudinal intermediate filaments is associated with sarcomeres of adult vertebrate skeletal muscle. J Cell Biol (1983) 2.16
Fluorescent localization of contractile proteins in tissue culture cells. Methods Enzymol (1982) 2.12
Filamin, a new high-molecular-weight protein found in smooth muscle and nonmuscle cells. Purification and properties of chicken gizzard filamin. Biochemistry (1977) 2.11
Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. Proc Natl Acad Sci U S A (1992) 2.07
Hemodynamic predictors of myocardial oxygen consumption during static and dynamic exercise. Circulation (1974) 2.01
Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo. EMBO J (1997) 1.96
VirD proteins of Agrobacterium tumefaciens are required for the formation of a covalent DNA--protein complex at the 5' terminus of T-strand molecules. EMBO J (1988) 1.93
Comparative genomics of the human and mouse T cell receptor loci. Immunity (2001) 1.92
Interaction of filamin with f-actin in solution. Proc Natl Acad Sci U S A (1977) 1.87
A mixture model with random-effects components for clustering correlated gene-expression profiles. Bioinformatics (2006) 1.85
Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile. J Cell Biol (1991) 1.85
Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: comparative evaluation of model-based linkage methods for affected sib pair data. Hum Hered (2001) 1.82
Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil. Clin Cancer Res (1999) 1.82
Passive tension and stiffness of vertebrate skeletal and insect flight muscles: the contribution of weak cross-bridges and elastic filaments. Biophys J (1993) 1.75
Incorporating language phenotypes strengthens evidence of linkage to autism. Am J Med Genet (2001) 1.65
Interaction of MHC class I molecules with the transporter associated with antigen processing. Science (1994) 1.65
Interplay between passive tension and strong and weak binding cross-bridges in insect indirect flight muscle. A functional dissection by gelsolin-mediated thin filament removal. J Gen Physiol (1993) 1.64
A bacterial peptide acting as a plant nuclear targeting signal: the amino-terminal portion of Agrobacterium VirD2 protein directs a beta-galactosidase fusion protein into tobacco nuclei. Proc Natl Acad Sci U S A (1990) 1.63
Titin is an extraordinarily long, flexible, and slender myofibrillar protein. Proc Natl Acad Sci U S A (1984) 1.63
Identification of an N2 line protein of striated muscle. Proc Natl Acad Sci U S A (1980) 1.63
The ultrasensitive silver "protein" stain also detects nanograms of nucleic acids. Biochem Biophys Res Commun (1981) 1.63
Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment. Br J Dermatol (2014) 1.63
Hematopoietic malignancies demonstrate loss-of-function mutations of BAX. Blood (1998) 1.61
Nebulette: a 107 kD nebulin-like protein in cardiac muscle. Cell Motil Cytoskeleton (1995) 1.61
The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. Genomics (1994) 1.60
Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region. Genomics (1992) 1.55
Structured entry of radiology reports using World Wide Web technology. Radiographics (1996) 1.54
Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex. EMBO J (1994) 1.53
Somatic PKD2 mutations in individual kidney and liver cysts support a "two-hit" model of cystogenesis in type 2 autosomal dominant polycystic kidney disease. J Am Soc Nephrol (1999) 1.50
Giant polypeptides of skeletal muscle titin: sedimentation equilibrium in guanidine hydrochloride. Biochem Biophys Res Commun (1988) 1.49
Polyproline II helix is a key structural motif of the elastic PEVK segment of titin. Biochemistry (2001) 1.49
p27Xic1, a Cdk inhibitor, promotes the determination of glial cells in Xenopus retina. Cell (1999) 1.46
Effect of propranolol on myocardial oxygen consumption and its hemodynamic correlates during upright exercise. Circulation (1973) 1.46
Concept of the homemade coronary stent: experimental results and initial clinical experience. Cathet Cardiovasc Diagn (1996) 1.42
Molecular consequences of activated microglia in the brain: overactivation induces apoptosis. J Neurochem (2001) 1.40
Association of standardized estimated glomerular filtration rate with the prevalence of hypertension among adults in the United States. J Hum Hypertens (2011) 1.40
Long-term results of heater probe thermocoagulation for patients with massive peptic ulcer bleeding: a prospective observation. Am J Gastroenterol (1995) 1.37
Nebulin as a giant actin-binding template protein in skeletal muscle sarcomere. Interaction of actin and cloned human nebulin fragments. FEBS Lett (1991) 1.36
Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression. Proc Natl Acad Sci U S A (1999) 1.32
Chinese women: behaviors and attitudes toward breast cancer education and screening. Womens Health Issues (2000) 1.29
Complete heart block complicating bacterial endocarditis. Circulation (1972) 1.28
Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations. Nat Genet (2000) 1.27
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Cytoskeletal matrix in striated muscle: the role of titin, nebulin and intermediate filaments. Adv Exp Med Biol (1984) 1.27
Identification of soil heavy metal sources from anthropogenic activities and pollution assessment of Fuyang County, China. Environ Monit Assess (2008) 1.26
Prostaglandin E2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness. J Immunol (1998) 1.26
Economic injury levels for western flower thrips (Thysanoptera: Thripidae) on greenhouse cucumber. J Econ Entomol (2000) 1.23
Nebulin cDNAs detect a 25-kilobase transcript in skeletal muscle and localize to human chromosome 2. Genomics (1988) 1.23
The cost of coverage: rural health insurance in China. Health Policy Plan (1996) 1.21
Calmodulin-sensitive interaction of human nebulin fragments with actin and myosin. Biochemistry (1994) 1.21
Predictive medicine: computational techniques in therapeutic decision-making. Comput Aided Surg (1999) 1.21
The molecular evolution of the vertebrate trypsinogens. J Mol Evol (1997) 1.20
Spontaneous neutrophil apoptosis involves caspase 3-mediated activation of protein kinase C-delta. J Biol Chem (1999) 1.20
Gel electrophoresis of giant proteins: solubilization and silver-staining of titin and nebulin from single muscle fiber segments. Electrophoresis (1993) 1.17
Breast cancer education program based in Asian grocery stores. J Cancer Educ (2000) 1.16
Transgenic mdx mice expressing dystrophin with a deletion in the actin-binding domain display a "mild Becker" phenotype. J Cell Biol (1996) 1.16
Intestinal expression of the human apoA-I gene in transgenic mice is controlled by a DNA region 3' to the gene in the promoter of the adjacent convergently transcribed apoC-III gene. J Lipid Res (1993) 1.15
The death-inducing signalling complex is recruited to lipid rafts in Fas-induced apoptosis. Biochem Biophys Res Commun (2002) 1.15
Modular motif, structural folds and affinity profiles of the PEVK segment of human fetal skeletal muscle titin. J Biol Chem (2000) 1.15
Development of novel dye-doped silica nanoparticles for biomarker application. J Biomed Opt (2001) 1.14
Role of configurational gating in intracomplex electron transfer from cytochrome c to the radical cation in cytochrome c peroxidase. Biochemistry (1999) 1.14
Early or delayed endoscopy for patients with peptic ulcer bleeding. A prospective randomized study. J Clin Gastroenterol (1996) 1.14
The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types. Nat Neurosci (2000) 1.13
Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer. J Clin Pathol (2014) 1.12
Fourier transform infrared spectroscopy approach for measurements of photoluminescence and electroluminescence in mid-infrared. Rev Sci Instrum (2012) 1.12
Adenovirus sequences required for replication in vivo. Nucleic Acids Res (1985) 1.10
The relationship between quadriceps muscle weakness and worsening of knee pain in the MOST cohort: a 5-year longitudinal study. Osteoarthritis Cartilage (2013) 1.09
Hevin, an antiadhesive extracellular matrix protein, is down-regulated in metastatic prostate adenocarcinoma. Cancer Res (1998) 1.09
Actual metal coverage at the neck is critical for flow-diverting stents in treating intracranial aneurysms. AJNR Am J Neuroradiol (2013) 1.09
Retinal detachment associated with coloboma of the choroid. Trans Am Ophthalmol Soc (1985) 1.09
Molecular beacons: novel fluorescent probes. Anal Chem (2000) 1.08
Helicobacter pylori-selective antibacterials based on inhibition of pyrimidine biosynthesis. J Biol Chem (2000) 1.08
Cloning, expression, and protein interaction of human nebulin fragments composed of varying numbers of sequence modules. J Biol Chem (1991) 1.08
Scanning sonar of rolling porpoises during prey capture dives. J Exp Biol (2010) 1.08
Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma. Oncogene (2010) 1.08
Ex vivo experiment on radiofrequency liver ablation with saline infusion through a screw-tip cannulated electrode. J Surg Res (1997) 1.06