Published in Brain Res on August 26, 1977
Bacterial toxins: cellular mechanisms of action. Microbiol Rev (1984) 3.42
Tetanus toxin. Microbiol Rev (1979) 2.25
Axonal and dendritic endocytic pathways in cultured neurons. J Cell Biol (1992) 2.19
Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons. J Cell Biol (1992) 2.09
Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport. J Cell Biol (1979) 1.28
Selective binding, uptake, and retrograde transport of tetanus toxin by nerve terminals in the rat iris. An electron microscope study using colloidal gold as a tracer. J Cell Biol (1978) 1.18
Anatomical substrates for direct interactions between hippocampus, medial prefrontal cortex, and the thalamic nucleus reuniens. Brain Struct Funct (2013) 0.98
Mammalian cell ganglioside-binding specificities of E. coli enterotoxins LT-IIb and variant LT-IIb(T13I). Glycobiology (2009) 0.96
Neuroanatomy goes viral! Front Neuroanat (2015) 0.93
Sprouting from chicken embryo dorsal root ganglia induced by nerve growth factor is specifically inhibited by affinity-purified antiganglioside antibodies. Proc Natl Acad Sci U S A (1982) 0.90
Extensive intraneuronal spread of horseradish peroxidase from a focus of vasogenic edema into remote areas of central nervous system. Observations on mouse central nervous system subjected to cortical cold injury. Acta Neuropathol (1986) 0.85
Connections of the juxtaventromedial region of the lateral hypothalamic area in the male rat. Front Syst Neurosci (2015) 0.80
Retrograde axonal transport of an exogenous enzyme covalently linked to B-IIb fragment of tetanus toxin. Biochem J (1990) 0.80
Uptake and anterograde axonal transport of wheat germ agglutinin from retina to optic tectum in the chick. J Cell Biol (1981) 0.78
A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped with the Tet-Off System. PLoS One (2017) 0.75
Anti-ganglioside antibodies are removed from circulation in mice by neuronal endocytosis. Brain (2016) 0.75
Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks. Nat Med (2001) 16.65
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (1984) 9.64
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc Natl Acad Sci U S A (1983) 7.01
Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A (1995) 5.25
Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 4.85
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J (2001) 4.85
Physiology of nerve growth factor. Physiol Rev (1980) 4.58
Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex. Science (1998) 4.57
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut (2004) 4.39
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture. Nature (1985) 4.31
Molecular cloning and expression of brain-derived neurotrophic factor. Nature (1989) 3.90
Purification of a new neurotrophic factor from mammalian brain. EMBO J (1982) 3.68
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature (1983) 3.56
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature (1992) 3.39
The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J (1984) 3.39
Neurotrophin-evoked rapid excitation through TrkB receptors. Nature (1999) 3.11
Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver. Pharmacogenetics (2001) 3.05
Nucleotide sequence of the human N-myc gene. Proc Natl Acad Sci U S A (1986) 2.99
Effects of concentration-dependent plasma protein binding on ceftriaxone kinetics. Clin Pharmacol Ther (1981) 2.93
Respiratory and irritant health effects of ambient volatile organic compounds. The Kanawha County Health Study. Am J Epidemiol (1993) 2.68
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther (2001) 2.62
The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60
Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54
Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals. Clin Pharmacol Ther (2007) 2.48
Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature (1988) 2.47
Telomere length in different tissues of elderly patients. Mech Ageing Dev (2000) 2.45
Oncogene amplification in tumor cells. Adv Cancer Res (1986) 2.44
Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol (1987) 2.40
Hemorrhage after pancreatoduodenectomy. Ann Surg (1998) 2.35
Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc. Nature (1984) 2.32
Increase in tyrosine hydroxylase activity after reserpine administration. J Pharmacol Exp Ther (1969) 2.32
Targeting the function of mature dendritic cells by human cytomegalovirus: a multilayered viral defense strategy. Immunity (2001) 2.24
Disruption of the CNTF gene results in motor neuron degeneration. Nature (1993) 2.22
Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proc Natl Acad Sci U S A (1992) 2.19
Neoplastic transformation by the human gene N-myc. Mol Cell Biol (1987) 2.17
Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci U S A (1983) 2.17
Human proto-oncogene N-myc encodes nuclear proteins that bind DNA. Mol Cell Biol (1986) 2.15
Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci U S A (1996) 2.10
Some pharmacological actions of the beta-adrenolytic agent Ro 3-3528 (6,7-dimethyl-alpha-[(isopropylamino) methyl]-2-benzofuranmethanol Hydrochloride). Angiologica (1967) 2.10
A role for BDNF in mechanosensation. Nat Neurosci (1998) 2.08
Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6. Pharmacogenetics (2001) 2.08
Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature (1990) 2.06
Frequency of C3435T polymorphism of MDR1 gene in African people. Lancet (2001) 2.02
Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update. Clin Pharmacol Ther (2013) 1.99
Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma. Proc Natl Acad Sci U S A (1984) 1.99
An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia (1968) 1.98
Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase I and II enzymes on their concentration levels in plasma. Clin Pharmacol Ther (2011) 1.98
Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci U S A (1997) 1.96
Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proc Natl Acad Sci U S A (1971) 1.96
Clinical Pharmacogenetics Implementation Consortium guidelines for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing. Clin Pharmacol Ther (2013) 1.94
Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J (1985) 1.93
Relation between the rate of stimulation and the quantity of noradrenaline liberated from sympathetic nerve endings in the isolated perfused spleen of the cat. J Physiol (1965) 1.92
Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol (1992) 1.87
Augmented expression of normal c-myc is sufficient for cotransformation of rat embryo cells with a mutant ras gene. Mol Cell Biol (1985) 1.84
Dual site of action of phenoxybenzamine in the cat's spleen; blockade of alpha-adrenergic receptors and inhibition of re-uptake of neurally released norepinephrine. Experientia (1964) 1.83
Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci (1985) 1.82
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature (1990) 1.80
Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci U S A (1991) 1.79
NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res (1983) 1.77
Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor. Nature (1987) 1.76
Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. Hum Mol Genet (1996) 1.76
Effect site concentration during propofol TCI sedation: a comparison of sedation score with two pharmacokinetic models. Anaesthesia (2007) 1.73
Expression of N-myc in teratocarcinoma stem cells and mouse embryos. Nature (1985) 1.72
Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur J Neurosci (1995) 1.72
Increased tyrosine hydroxylase activity after drug-induced alteration of sympathetic transmission. Nature (1969) 1.72
Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J (1984) 1.71
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature (1993) 1.71
The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport (1993) 1.70
Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A (1987) 1.70
Single-dose pharmacokinetics of Ro 17-2301 (AMA-1080), a monocyclic beta-lactam, in humans. Antimicrob Agents Chemother (1984) 1.70
Sensory neurons in culture: changing requirements for survival factors during embryonic development. Proc Natl Acad Sci U S A (1980) 1.69
UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo. Clin Pharmacol Ther (2009) 1.67
Central adrenergic neurones and the initiation and development of experimental hypertension. Experientia (1972) 1.67
Trans-synaptic induction of adrenal tyrosine hydroxylase. J Pharmacol Exp Ther (1969) 1.67
Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine. Gut (2003) 1.66
Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci (1986) 1.64
Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol (1992) 1.64
Pharmacokinetics of cefetamet (Ro 15-8074) and cefetamet pivoxil (Ro 15-8075) after intravenous and oral doses in humans. Antimicrob Agents Chemother (1988) 1.64
Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. Am J Hum Genet (1998) 1.61
Electronmicroscopic localization of 5-hydroxydopamine (3,4,5-trihydroxy-phenyl-ethylamine), a new 'false' sympathetic transmitter. Experientia (1967) 1.61
A case-crossover study of fine particulate matter air pollution and onset of congestive heart failure symptom exacerbation leading to hospitalization. Am J Epidemiol (2006) 1.60
Pharmacokinetics of Rocephin, a highly active new cephalosporin with an exceptionally long biological half-life. Chemotherapy (1981) 1.59
Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma. Proc Natl Acad Sci U S A (1984) 1.59
Nerve growth factor in mouse and rat serum: correlation between bioassay and radioimmunoassay determinations. Proc Natl Acad Sci U S A (1978) 1.59
Single-dose pharmacokinetics of ceftriaxone in infants and young children. Antimicrob Agents Chemother (1982) 1.59
Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci (1994) 1.57
Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol (1985) 1.57
Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc Natl Acad Sci U S A (1997) 1.55
Potentiation by tetraethylammonium of the response of the cat spleen to postganglionic sympathetic nerve stimulation. J Pharmacol Exp Ther (1967) 1.54
Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci (1990) 1.53
The N-Myc oncoprotein is associated in vivo with the phosphoprotein Max(p20/22) in human neuroblastoma cells. EMBO J (1991) 1.52
Specificity of the retrograde axonal transport of nerve growth factor. Brain Res (1974) 1.52
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J Cell Biol (1992) 1.51
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells. Pharmacogenetics (2001) 1.50
Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci U S A (1978) 1.50
Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroectodermal origin. Cancer Res (1993) 1.50
Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat. Ann Neurol (1994) 1.49