Published in Biochemistry on December 23, 1980
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Micrometer-scale domains in fibroblast plasma membranes. J Cell Biol (1987) 4.01
Translational diffusion in phospholipid monolayers measured by fluorescence microphotolysis. Proc Natl Acad Sci U S A (1983) 3.03
A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor. J Cell Biol (1991) 3.03
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Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures. J Cell Biol (1986) 2.51
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Fluorescence probe partitioning between Lo/Ld phases in lipid membranes. Biochim Biophys Acta (2007) 2.25
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Lateral diffusion of phospholipids in the plasma membrane of soybean protoplasts: Evidence for membrane lipid domains. Proc Natl Acad Sci U S A (1986) 1.57
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Changes in sperm plasma membrane lipid diffusibility after hyperactivation during in vitro capacitation in the mouse. J Cell Biol (1986) 1.04
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Interaction of the sperm adhesive protein, bindin, with phospholipid vesicles. I. Specific association of bindin with gel-phase phospholipid vesicles. J Cell Biol (1985) 0.98
Lipid domains in the ram sperm plasma membrane demonstrated by differential scanning calorimetry. Proc Natl Acad Sci U S A (1990) 0.94
Tuning membrane phase separation using nonlipid amphiphiles. Biophys J (2012) 0.92
Atomistic simulation of lipid and DiI dynamics in membrane bilayers under tension. Phys Chem Chem Phys (2010) 0.90
Combining fluorescence lifetime and polarization microscopy to discriminate phase separated domains in giant unilamellar vesicles. Biophys J (2008) 0.90
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Partitioning of pyrene-labeled phospho- and sphingolipids between ordered and disordered bilayer domains. Biophys J (2004) 0.89
Regionalization and lateral diffusion of membrane proteins in unfertilized and fertilized mouse eggs. J Cell Biol (1983) 0.88
Location-dependent coronary artery diffusive and convective mass transport properties of a lipophilic drug surrogate measured using nonlinear microscopy. Pharm Res (2012) 0.83
Luteolysis-induced changes in phase composition and fluidity of bovine luteal cell membranes. Proc Natl Acad Sci U S A (1982) 0.83
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Universal Approach to FRAP Analysis of Arbitrary Bleaching Patterns. Sci Rep (2015) 0.81
Cytoskeletal modulation of lipid interactions regulates Lck kinase activity. J Biol Chem (2012) 0.80
Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells. Oncotarget (2015) 0.80
Modification of plasma membrane organization in tobacco cells elicited by cryptogein. Plant Physiol (2013) 0.79
Plasma membrane lipid diffusion and composition of sea urchin egg membranes vary with ocean temperature. Chem Phys Lipids (2007) 0.77
The development of regionalized lipid diffusibility in the germ cell plasma membrane during spermatogenesis in the mouse. J Cell Biol (1986) 0.77
Membrane organization and function of the serotonin(1A) receptor. Cell Mol Neurobiol (2007) 0.77
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell (1989) 13.41
Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway. Cell (1990) 9.19
The mammalian gene collection. Science (1999) 7.19
Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160. Proc Natl Acad Sci U S A (1988) 6.33
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell (1991) 6.30
Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein. Nature (1992) 6.11
Receptor-mediated endocytosis of transferrin and the uptake of fe in K562 cells: identification of a nonlysosomal acidic compartment. Proc Natl Acad Sci U S A (1982) 5.74
Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor. Proc Natl Acad Sci U S A (1990) 5.35
Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer. Proc Natl Acad Sci U S A (1988) 4.90
Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. Science (1988) 4.86
A systematic, high-resolution linkage of the cytogenetic and physical maps of the human genome. Nat Genet (2000) 4.78
Binding of apotransferrin to K562 cells: explanation of the transferrin cycle. Proc Natl Acad Sci U S A (1983) 4.68
A permease-oxidase complex involved in high-affinity iron uptake in yeast. Science (1996) 4.60
Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins. Cell (1988) 4.42
A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains. Cell (1992) 4.39
Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science (1988) 4.35
Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions. Science (1986) 4.30
Inhibition of transcription elongation by the VHL tumor suppressor protein. Science (1995) 4.23
ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes. Proc Natl Acad Sci U S A (1992) 4.22
Identification of the components of the murine T cell antigen receptor complex. Cell (1985) 4.20
Identification of the iron-responsive element for the translational regulation of human ferritin mRNA. Science (1987) 4.20
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell (1991) 4.17
Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action. J Cell Biol (1990) 3.90
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proc Natl Acad Sci U S A (1996) 3.88
Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell (1994) 3.88
Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments. J Cell Biol (1995) 3.82
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. Proc Natl Acad Sci U S A (1997) 3.75
Receptor-mediated endocytosis of transferrin in K562 cells. J Biol Chem (1983) 3.65
Failure to synthesize the T cell CD3-zeta chain: structure and function of a partial T cell receptor complex. Cell (1988) 3.59
Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction. Science (1989) 3.54
Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex. Proc Natl Acad Sci U S A (1999) 3.43
Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells. Proc Natl Acad Sci U S A (1998) 3.36
Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein. Science (1991) 3.33
Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor. Cell (1986) 3.30
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice. Proc Natl Acad Sci U S A (1997) 3.27
Membrane protein association by potential intramembrane charge pairs. Nature (1991) 3.27
Lipid domains in membranes. Evidence derived from structural perturbations induced by free fatty acids and lifetime heterogeneity analysis. J Biol Chem (1980) 3.20
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Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation. Nature (1989) 3.02
A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. Proc Natl Acad Sci U S A (1987) 2.89
Ferric reductase of Saccharomyces cerevisiae: molecular characterization, role in iron uptake, and transcriptional control by iron. Proc Natl Acad Sci U S A (1992) 2.87
Genetic evidence that ferric reductase is required for iron uptake in Saccharomyces cerevisiae. Mol Cell Biol (1990) 2.83
Lateral diffusion in planar lipid bilayers. Science (1977) 2.82
A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA. Proc Natl Acad Sci U S A (1989) 2.81
AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiae. EMBO J (1995) 2.76
Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3' UTR and does not involve poly(A) tail shortening. EMBO J (1994) 2.70
Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon. Science (1992) 2.67
Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly. J Cell Biol (1989) 2.65
Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma. Biochim Biophys Acta (1996) 2.64
Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast. EMBO J (1996) 2.62
New opportunities for uncovering the molecular basis of cancer. Nat Genet (1997) 2.61
Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor. Proc Natl Acad Sci U S A (1987) 2.58
Molecular cloning of the zeta chain of the T cell antigen receptor. Science (1988) 2.58
The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake. J Biol Chem (1994) 2.57
Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3' untranslated region of the mRNA. EMBO J (1989) 2.54
Fate of receptor and ligand during endocytosis of asialoglycoproteins by isolated hepatocytes. Proc Natl Acad Sci U S A (1982) 2.54
The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake. Proc Natl Acad Sci U S A (1995) 2.50
T cell activation induces rapid tyrosine phosphorylation of a limited number of cellular substrates. J Biol Chem (1989) 2.50
Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains. Cell (1990) 2.49
Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase. J Cell Biol (1996) 2.47
Iron-sulfur clusters as biosensors of oxidants and iron. Trends Biochem Sci (1996) 2.46
A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules. Nature (1991) 2.45
Intracellular dissociation of receptor-bound asialoglycoproteins in cultured hepatocytes. A pH-mediated nonlysosomal event. J Biol Chem (1983) 2.45
Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: functional implications. Cell (1991) 2.37
Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus. J Cell Biol (1991) 2.33
T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins. Proc Natl Acad Sci U S A (1991) 2.32
A model for the structure and functions of iron-responsive elements. Gene (1988) 2.29
Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements. Mol Cell Biol (1989) 2.26
The concept of lipid domains in membranes. J Cell Biol (1982) 2.26
A peptide sequence confers retention and rapid degradation in the endoplasmic reticulum. Science (1990) 2.17
Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding. Proc Natl Acad Sci U S A (1992) 2.17
ARF: a key regulatory switch in membrane traffic and organelle structure. Curr Opin Cell Biol (1994) 2.15
Family of disulphide-linked dimers containing the zeta and eta chains of the T-cell receptor and the gamma chain of Fc receptors. Nature (1990) 2.14
Only high-affinity receptors for interleukin 2 mediate internalization of ligand. Proc Natl Acad Sci U S A (1986) 2.12
Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum. EMBO J (1991) 2.08
Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment. J Cell Biol (1988) 2.07
Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster. Proc Natl Acad Sci U S A (1992) 2.06
A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1. Cell (1992) 2.06
Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor. J Biol Chem (1992) 2.05
The T cell antigen receptor zeta chain is tyrosine phosphorylated upon activation. J Biol Chem (1988) 2.04
Rapid internalization of the transferrin receptor in K562 cells is triggered by ligand binding or treatment with a phorbol ester. Proc Natl Acad Sci U S A (1984) 2.04
Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein. Proc Natl Acad Sci U S A (1990) 2.03
Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex. Proc Natl Acad Sci U S A (1988) 1.95
The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein. Proc Natl Acad Sci U S A (1989) 1.95
Copper-dependent degradation of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p in the apparent absence of endocytosis. EMBO J (1996) 1.93
Translation and the stability of mRNAs encoding the transferrin receptor and c-fos. Proc Natl Acad Sci U S A (1991) 1.93
Regulating the retention of T-cell receptor alpha chain variants within the endoplasmic reticulum: Ca(2+)-dependent association with BiP. J Cell Biol (1991) 1.93
Characterization of an anti-peptide antibody that recognizes the murine analogue of the human T cell antigen receptor-T3 delta-chain. J Immunol (1986) 1.91
Charge clusters and the orientation of membrane proteins. J Membr Biol (1982) 1.87
Biosynthetic regulation of the human transferrin receptor by desferrioxamine in K562 cells. J Biol Chem (1984) 1.87
Voltage-dependent trans-bilayer orientation of melittin. J Biol Chem (1982) 1.86
A regulated RNA binding protein also possesses aconitase activity. Proc Natl Acad Sci U S A (1991) 1.82
Structure and dynamics of the iron responsive element RNA: implications for binding of the RNA by iron regulatory binding proteins. J Mol Biol (1997) 1.81
Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide. Proc Natl Acad Sci U S A (1990) 1.80
Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation. J Biol Chem (1994) 1.79
Disulfide linkage of the zeta and eta chains of the T cell receptor. Possible identification of two structural classes of receptors. J Biol Chem (1988) 1.79
Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro. Nature (1994) 1.79
Monensin inhibits intracellular dissociation of asialoglycoproteins from their receptor. J Cell Biol (1983) 1.77
Class II MHC molecules can use the endogenous pathway of antigen presentation. Nature (1990) 1.77
Feedback control of the metaphase-anaphase transition in sea urchin zygotes: role of maloriented chromosomes. J Cell Biol (1994) 1.77