Published in Nihon Geka Hokan on March 01, 1978
Taxonomy of four marine bacterial strains that produce tetrodotoxin. Int J Syst Bacteriol (1990) 1.91
Detection of sodium channel toxins: directed cytotoxicity assays of purified ciguatoxins, brevetoxins, saxitoxins, and seafood extracts. J AOAC Int (1995) 1.63
Production of tetrodotoxin and its derivatives by Pseudomonas sp. isolated from the skin of a pufferfish. Toxicon (1987) 1.47
Two analogs of azaspiracid isolated from mussels, Mytilus edulis, involved in human intoxication in Ireland. Nat Toxins (1999) 1.38
The structure elucidation and biological activities of high molecular weight algal toxins: maitotoxin, prymnesins and zooxanthellatoxins. Nat Prod Rep (2000) 1.31
New saxitoxin analogues from the freshwater filamentous cyanobacterium Lyngbya wollei. Nat Toxins (1997) 1.28
Multiple organ damage caused by a new toxin azaspiracid, isolated from mussels produced in Ireland. Toxicon (2000) 1.23
Structures of azaspiracid analogs, azaspiracid-4 and azaspiracid-5, causative toxins of azaspiracid poisoning in Europe. Biosci Biotechnol Biochem (2001) 1.20
Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship. Biochem J (1992) 1.18
Maitotoxin, a Ca2+ channel activator candidate. J Biol Chem (1982) 1.18
First occurrence of tetrodotoxin in a dendrobatid frog (Colostethus inguinalis), with further reports for the bufonid genus Atelopus. Toxicon (1994) 1.17
A protein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels. Toxicon (1996) 1.16
Comparison of oral and intraperitoneal toxicity of yessotoxin towards mice. Toxicon (2002) 1.16
Origins of ciguatera fish poisoning: a new dinoflagellate, Gambierdiscus toxicus Adachi and Fukuyo, definitively involved as a causal agent. Toxicon (1980) 1.09
Dinoflagellate Gymnodinium catenatum as the source of paralytic shellfish toxins in Tasmanian shellfish. Toxicon (1987) 1.07
Electrospray ionization mass spectrometry of tetrodotoxin and its analogs: liquid chromatography/mass spectrometry, tandem mass spectrometry, and liquid chromatography/tandem mass spectrometry. Anal Biochem (2001) 1.07
Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin. Jpn J Cancer Res (1988) 1.06
Aplysiatoxin and debromoaplysiatoxin as the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii. Toxicon (1996) 1.06
Some chemical properties of maitotoxin, a putative calcium channel agonist isolated from a marine dinoflagellate. J Biochem (1988) 1.05
Ca2+ channel activating function of maitotoxin, the most potent marine toxin known, in clonal rat pheochromocytoma cells. J Biol Chem (1983) 1.02
Preparation of monoclonal antibodies against okadaic acid prepared from the sponge Halichondria okadai. Toxicon (1989) 1.01
Oral and intraperitoneal acute toxicity studies of yessotoxin and homoyessotoxins in mice. Toxicon (2003) 1.00
Brevetoxin B4 isolated from greenshell mussels Perna canaliculus, the major toxin involved in neurotoxic shellfish poisoning in New Zealand. Nat Toxins (1999) 0.99
Tetrodotoxin derivatives in puffer fish. Toxicon (1985) 0.99
Toxicologic evaluation of yessotoxin. Nat Toxins (1997) 0.99
Short-term oral toxicity of homoyessotoxins, yessotoxin and okadaic acid in mice. Toxicon (2004) 0.99
Identification of Protoceratium reticulatum as the biogenetic origin of yessotoxin. Nat Toxins (1997) 0.98
Structure-activity relationship within a series of okadaic acid derivatives. Carcinogenesis (1990) 0.97
Effects of ciguatoxin and maitotoxin on the isolated guinea pig atria. Res Commun Chem Pathol Pharmacol (1979) 0.96
Affinity of okadaic acid to type-1 and type-2A protein phosphatases is markedly reduced by oxidation of its 27-hydroxyl group. Biochem J (1994) 0.96
Distribution of tetrodotoxin, 6-epitetrodotoxin, and 11-deoxytetrodotoxin in newts. Toxicon (1990) 0.95
Human fatality due to ingestion of the crab Demania reynaudii that contained a palytoxin-like toxin. Toxicon (1988) 0.94
Effects of specific modifications of several hydroxyls of tetrodotoxin on its affinity to rat brain membrane. J Pharmacol Exp Ther (1999) 0.94
The occurrence of paralytic shellfish toxins in two species of xanthid crab from Suva barrier reef, Fiji Islands. Toxicon (1983) 0.94
Identification of putative palytoxin as the cause of clupeotoxism. Toxicon (1999) 0.94
Histopathological studies on experimental marine toxin poisoning--5. The effects in mice of yessotoxin isolated from Patinopecten yessoensis and of a desulfated derivative. Toxicon (1990) 0.93
Contractile response of the rabbit aorta to maitotoxin, the most potent marine toxin. J Physiol (1983) 0.92
Selective stimulation of Ca2+ flux in cells by maitotoxin. Eur J Pharmacol (1992) 0.92
Suitability of the MTT-based cytotoxicity assay to detect okadaic acid contamination of mussels. Toxicon (1996) 0.92
Purification, characterization, and cDNA cloning of a novel soluble saxitoxin and tetrodotoxin binding protein from plasma of the puffer fish, Fugu pardalis. Eur J Biochem (2001) 0.92
Excitatory effect of the most potent marine toxin, maitotoxin, on the guinea-pig vas deferens. J Pharmacol Exp Ther (1983) 0.92
Quantitative determination of marine toxins associated with diarrhetic shellfish poisoning by liquid chromatography coupled with mass spectrometry. J Chromatogr A (2001) 0.91
Sensitive detection of apoptogenic toxins in suspension cultures of rat and salmon hepatocytes. Toxicon (1998) 0.90
Manauealides, some of the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii. J Nat Prod (1997) 0.90
Azaspiracid shellfish poisoning: unusual toxin dynamics in shellfish and the increased risk of acute human intoxications. Food Addit Contam (2002) 0.90
Clinical and laboratory findings implicating palytoxin as cause of ciguatera poisoning due to Decapterus macrosoma (mackerel). Toxicon (1989) 0.90
Binding properties of (3)H-PbTx-3 and (3)H-saxitoxin to brain membranes and to skeletal muscle membranes of puffer fish Fugu pardalis and the primary structure of a voltage-gated Na(+) channel alpha-subunit (fMNa1) from skeletal muscle of F. pardalis. Biochem Biophys Res Commun (2000) 0.89
Estimation of the rate constants associated with the inhibitory effect of okadaic acid on type 2A protein phosphatase by time-course analysis. Biochem J (1992) 0.89
Interspecies distribution and possible origin of tetrodotoxin. Ann N Y Acad Sci (1986) 0.89
Actions of 4-epitetrodotoxin and anhydrotetrodotoxin on the squid axon. Toxicon (1985) 0.89
Multiresidue method for determination of algal toxins in shellfish: single-laboratory validation and interlaboratory study. J AOAC Int (2005) 0.88
A sensitive and specific determination method for azaspiracids by liquid chromatography mass spectrometry. Nat Toxins (1999) 0.88
Toxicities and distribution of tetrodotoxin in the tissues of puffer fish found in the coast of the Baja California Peninsula, Mexico. Toxicon (2000) 0.88
Further report of the occurrence of tetrodotoxin in Atelopus species (family: Bufonidae). Toxicon (1995) 0.87
Structure elucidation of ostreocin D, a palytoxin analog isolated from the dinoflagellate Ostreopsis siamensis. Biosci Biotechnol Biochem (2001) 0.86
Maitotoxin effects are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry. Mol Pharmacol (1992) 0.86
Maitotoxin stimulates hormonal release and calcium flux in rat anterior pituitary cells in vitro. Am J Physiol (1984) 0.86
New insights into maitotoxin action. Eur J Biochem (1988) 0.86
Actin cytoskeleton of rabbit intestinal cells is a target for potent marine phycotoxins. J Exp Biol (2005) 0.85
Isolation and structural assignment of 5-deoxytetrodotoxin from the puffer fish Fugu poecilonotus. Biosci Biotechnol Biochem (1999) 0.85
The mechanism of action of maitotoxin in relation to Ca2+ movements in guinea-pig and rat cardiac muscles. Br J Pharmacol (1985) 0.85
Confirmation of anatoxin-a(s), in the cyanobacterium Anabaena lemmermannii, as the cause of bird kills in Danish lakes. Toxicon (1997) 0.85
Maitotoxin-induced free Ca changes in single rat hepatocytes. Cell Signal (1999) 0.85
Actions of 6-epitetrodotoxin and 11-deoxytetrodotoxin on the frog skeletal muscle fiber. Toxicon (1992) 0.84
Liquid chromatography-electrospray ionization mass spectrometry of the diarrhetic shellfish-poisoning toxins okadaic acid, dinophysistoxin-1 and pectenotoxin-6 in bivalves. J Chromatogr A (2000) 0.84
Isolation and structure of ciguatoxin-4A, a new ciguatoxin precursor, from cultures of dinoflagellate Gambierdiscus toxicus and parrotfish Scarus gibbus. Biosci Biotechnol Biochem (1996) 0.84
Ultrastructural damage to heart tissue from repeated oral exposure to yessotoxin resolves in 3 months. Toxicon (2008) 0.83
Occurrence of toxic crabs in Ryukyu and Amami Islands. Toxicon (1967) 0.82
Monthly variations in diarrhetic toxins and yessotoxin in shellfish from coast to the inner part of the Sognefjord, Norway. Toxicon (2001) 0.82
Na(+)-permeable channels induced by maitotoxin in guinea-pig single ventricular cells. Eur J Pharmacol (1996) 0.82
Maitotoxin: effects on calcium channels, phosphoinositide breakdown, and arachidonate release in pheochromocytoma PC12 cells. Mol Pharmacol (1990) 0.82
Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. J Pharmacol Exp Ther (1990) 0.82
Maitotoxin, a potent, general activator of phosphoinositide breakdown. FEBS Lett (1989) 0.82
Yessotoxin in mussels of the northern Adriatic Sea. Toxicon (1997) 0.82
The 1990 United States-Japan seminar on bioorganic marine chemistry, meeting report. J Nat Prod (1992) 0.82
Maitotoxin-induced calcium entry in human lymphocytes: modulation by yessotoxin, Ca(2+) channel blockers and kinases. Cell Signal (2001) 0.82
Cardiotoxic effects of maitotoxin, a principal toxin of seafood poisoning, on guinea pig and rat cardiac muscle. J Pharmacol Exp Ther (1986) 0.81
Contraction and increase in tissue calcium content induced by maitotoxin, the most potent known marine toxin, in intestinal smooth muscle. Br J Pharmacol (1983) 0.81
Occurrence of saxitoxin in puffer fish. Toxicon (1984) 0.81
Liquid chromatographic methods for the isolation and identification of new pectenotoxin-2 analogues from marine phytoplankton and shellfish. J Chromatogr A (1999) 0.80
The effects of maitotoxin on 45Ca2+ flux and hormone release in GH3 rat pituitary cells. Endocrinology (1985) 0.80
Maitotoxin activates quantal transmitter release at the neuromuscular junction: evidence for elevated intraterminal Ca2+ in the motor nerve terminal. Brain Res (1985) 0.80
Cytoskeletal toxicity of pectenotoxins in hepatic cells. Br J Pharmacol (2008) 0.80
[Actin depolymerizing action by marine toxin, pectenotoxin-2]. Nihon Yakurigaku Zasshi (1999) 0.80
Repeated oral co-exposure to yessotoxin and okadaic acid: a short term toxicity study in mice. Toxicon (2013) 0.80
Assessment of potential activation of gonyautoxin V in the stomach of mice and rats. Toxicon (1984) 0.80
Biological activities of prymnesin-2 isolated from a red tide alga Prymnesium parvum. Nat Toxins (1998) 0.80
11-Oxo-tetrodotoxin and a specifically labelled 3H-tetrodotoxin. Toxicon (1996) 0.80
Mechanisms underlying the hemolytic and ichthyotoxic activities of maitotoxin. Nat Toxins (1999) 0.80
Fluorometric analysis of pectenotoxin-2 in microalgal samples by high performance liquid chromatography. Nat Toxins (1999) 0.80
Fatal mass poisoning in Madagascar following ingestion of a shark (Carcharhinus leucas): clinical and epidemiological aspects and isolation of toxins. Toxicon (1995) 0.80
Mechanism of maitotoxin-stimulated phosphoinositide breakdown in HL-60 cells. J Pharmacol Exp Ther (1990) 0.79
Progress on chemical knowledge of ciguatoxins. Bull Soc Pathol Exot (1992) 0.79
Biological activities of novel polyether antifungals, gambieric acids A and B from a marine dinoflagellate Gambierdiscus toxicus. J Antibiot (Tokyo) (1993) 0.79
Maitotoxin-induced intracellular calcium rise in PC12 cells: involvement of dihydropyridine-sensitive and omega-conotoxin-sensitive calcium channels and phosphoinositide breakdown. J Neurochem (1992) 0.78
Effect of maitotoxin analogues on calcium influx and phosphoinositide breakdown in cultured cells. Toxicon (1991) 0.78
Calcium-dependent effects of maitotoxin on phosphoinositide breakdown and on cyclic AMP accumulation in PC12 and NCB-20 cells. Mol Pharmacol (1989) 0.78