Published in Mol Cell Biol on April 01, 1995
Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J Cell Biol (1996) 2.71
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. Mol Cell Biol (1996) 2.47
A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc Natl Acad Sci U S A (1996) 2.36
Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes (2009) 1.91
p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB. Mol Cell Biol (1998) 1.39
Expression of E1A in terminally differentiated muscle cells reactivates the cell cycle and suppresses tissue-specific genes by separable mechanisms. Mol Cell Biol (1996) 1.33
p21 Disrupts the interaction between cdk2 and the E2F-p130 complex. Mol Cell Biol (1996) 1.16
Regulation of differentiation by HBP1, a target of the retinoblastoma protein. Mol Cell Biol (1998) 1.13
MyoD synergizes with the E-protein HEB beta to induce myogenic differentiation. Mol Cell Biol (2006) 1.11
Differential regulation of the retinoblastoma family of proteins during cell proliferation and differentiation. Biochem J (1998) 0.99
Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB. Mol Biol Cell (2008) 0.98
J domain-independent regulation of the Rb family by polyomavirus large T antigen. J Virol (2000) 0.94
Subcellular compartmentalization of E2F family members is required for maintenance of the postmitotic state in terminally differentiated muscle. J Cell Biol (2000) 0.88
Distinct roles of E2F recognition sites as positive or negative elements in regulation of the DNA polymerase alpha 180 kDa catalytic subunit gene promoter during Drosophila development. Nucleic Acids Res (1997) 0.85
Activation of CREB/ATF sites by polyomavirus large T antigen. J Virol (2005) 0.84
Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell (1987) 22.17
Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature (1978) 11.49
E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (1992) 10.28
The E2F transcription factor is a cellular target for the RB protein. Cell (1991) 9.62
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell (1992) 9.19
Cellular targets for transformation by the adenovirus E1A proteins. Cell (1989) 7.53
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell (1992) 6.32
The MyoD family and myogenesis: redundancy, networks, and thresholds. Cell (1993) 6.24
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev (1992) 5.73
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes Dev (1993) 5.54
Retinoblastoma protein switches the E2F site from positive to negative element. Nature (1992) 5.47
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev (1993) 5.32
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell (1992) 5.05
Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev (1994) 4.93
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell (1993) 4.90
Identification of a growth suppression domain within the retinoblastoma gene product. Genes Dev (1992) 4.56
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F. Cell (1991) 4.42
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell (1991) 4.24
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature (1992) 4.21
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev (1993) 4.14
Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell (1994) 4.01
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell (1991) 3.98
Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. Genes Dev (1992) 3.96
The retinoblastoma protein binds to a family of E2F transcription factors. Mol Cell Biol (1993) 3.75
Cell cycle regulation of the human cdc2 gene. EMBO J (1992) 3.69
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. Proc Natl Acad Sci U S A (1989) 3.67
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell (1992) 3.64
Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol Cell Biol (1992) 3.58
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Mol Cell Biol (1993) 3.54
An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J (1993) 3.48
Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell (1991) 3.47
Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev (1994) 3.47
Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev (1993) 3.41
DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. Trends Biochem Sci (1994) 3.32
Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev (1994) 3.27
Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene. Mol Cell Biol (1988) 3.24
Cyclin A and the retinoblastoma gene product complex with a common transcription factor. Nature (1991) 3.15
The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev (1993) 3.10
A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway. EMBO J (1990) 3.07
Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells. Science (1994) 3.05
E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev (1994) 3.05
E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev (1994) 2.86
The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding. Mol Cell Biol (1989) 2.83
Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter. Genes Dev (1989) 2.82
Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene. Mol Cell Biol (1992) 2.78
Interactions of the p107 and Rb proteins with E2F during the cell proliferation response. EMBO J (1993) 2.70
Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science (1993) 2.70
A new component of the transcription factor DRTF1/E2F. Nature (1993) 2.65
E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product. Proc Natl Acad Sci U S A (1993) 2.61
Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J (1993) 2.55
Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol Cell Biol (1994) 2.44
The retinoblastoma protein as a transcriptional repressor. Trends Cell Biol (1993) 2.41
Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol Cell Biol (1993) 2.34
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex. EMBO J (1987) 2.30
Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product. Mol Cell Biol (1990) 2.27
Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen. EMBO J (1990) 2.26
Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding. Mol Cell Biol (1992) 2.13
Adenovirus E1A products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters. Nature (1988) 1.95
Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1. J Virol (1993) 1.78
The transcription factor E2F-1 mediates the autoregulation of RB gene expression. Mol Cell Biol (1994) 1.73
Transcriptional repression by the Rb-related protein p107. Mol Biol Cell (1993) 1.72
A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4. Mol Cell Biol (1993) 1.70
Characterization of pp85, a target of oncogenes and growth factor receptors. Mol Cell Biol (1990) 1.51
Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein. Cell (1994) 1.44
Differentiation requires continuous active control. Annu Rev Biochem (1992) 1.41
Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. Mol Cell Biol (1993) 1.31
Cloning, chromosomal location, and characterization of mouse E2F1. Mol Cell Biol (1994) 1.25
Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein. Oncogene (1993) 1.23
The retinoblastoma protein region required for interaction with the E2F transcription factor includes the T/E1A binding and carboxy-terminal sequences. DNA Cell Biol (1992) 1.07
Negative control of the helix-loop-helix family of myogenic regulators in the NFB mutant. Cell (1990) 1.06
Retinoblastoma antioncogene is involved in the inhibition of myogenesis by polyomavirus large T antigen. Cell Growth Differ (1994) 0.97
Inhibition of in vitro myogenic differentiation by a polyomavirus early function. Oncogene (1992) 0.93
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature (1985) 7.10
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell (1987) 5.87
Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit. J Biol Chem (1993) 3.14
Tumor antigens induced by nontransforming mutants of polyoma virus. Cell (1978) 2.92
Comparison of phosphorylation of two polyoma virus middle T antigens in vivo and in vitro. J Virol (1981) 2.85
IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85. Proc Natl Acad Sci U S A (1992) 2.75
Phosphatidylinositol metabolism and polyoma-mediated transformation. Proc Natl Acad Sci U S A (1986) 2.62
Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol Cell Biol (1994) 2.44
Validating biomarkers of treatable mechanisms in irritable bowel syndrome. Neurogastroenterol Motil (2014) 2.11
Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins. J Virol (1984) 2.02
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity. Mol Cell Biol (1993) 1.95
HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family. Genes Dev (1997) 1.83
Don't ask, don't tell: patterns of HIV disclosure among HIV positive men who have sex with men with recent STI practising high risk behaviour in Los Angeles and Seattle. Sex Transm Infect (2004) 1.81
Cellular proteins that associate with the middle and small T antigens of polyomavirus. J Virol (1988) 1.78
Transforming genes and gene products of polyoma and SV40. CRC Crit Rev Biochem (1982) 1.61
Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. EMBO J (2001) 1.45
Accuracy and usefulness of a breath alcohol analyzer. Ann Emerg Med (1984) 1.44
Functions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins. Mol Cell Biol (1999) 1.43
The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin. Cell (1999) 1.40
Antibody to the nonapeptide Glu-Glu-Glu-Glu-Tyr-Met-Pro-Met-Glu is specific for polyoma middle T antigen and inhibits in vitro kinase activity. J Biol Chem (1982) 1.37
The T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequence. J Virol (1991) 1.32
Performance characteristics of scintigraphic measurement of gastric emptying of solids in healthy participants. Neurogastroenterol Motil (2012) 1.31
Expression of polyoma early gene products in E. coli. Nucleic Acids Res (1985) 1.29
Conformational changes associated with f-1 histone-deoxyribonucleic acid complexes. Circular dichroism studies. Biochemistry (1970) 1.29
Venous thromboembolism in patients undergoing rehabilitation for stroke. Arch Phys Med Rehabil (1992) 1.26
The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function. J Virol (1997) 1.21
CagA-producing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in Korea. Br J Cancer (2006) 1.17
Mechanisms of transformation by polyoma virus middle T antigen. Biochim Biophys Acta (1989) 1.17
The value of cerebrospinal fluid antiviral antibody in the diagnosis of neurologic disease produced by varicella zoster virus. J Neurol Sci (1998) 1.17
Restoration of plakoglobin expression in bladder carcinoma cell lines suppresses cell migration and tumorigenic potential. Br J Cancer (2005) 1.13
Regulation of differentiation by HBP1, a target of the retinoblastoma protein. Mol Cell Biol (1998) 1.13
The retinoblastoma protein region required for interaction with the E2F transcription factor includes the T/E1A binding and carboxy-terminal sequences. DNA Cell Biol (1992) 1.07
Signal transduction. The hunt for Ras targets. Nature (1994) 1.06
Phosphorylation of polyomavirus large T antigen: effects of viral mutations and cell growth state. J Virol (1987) 1.05
Body mass, tobacco smoking, alcohol drinking and risk of cancer of the small intestine--a pooled analysis of over 500,000 subjects in the Asia Cohort Consortium. Ann Oncol (2011) 1.03
Dietary patterns and the prevalence of metabolic syndrome in Korean women. Nutr Metab Cardiovasc Dis (2010) 1.01
Effect of dietary soy intake on breast cancer risk according to menopause and hormone receptor status. Eur J Clin Nutr (2010) 1.00
Genetic polymorphisms of OPG, RANK, and ESR1 and bone mineral density in Korean postmenopausal women. Calcif Tissue Int (2005) 0.99
Activation and repression of p21(WAF1/CIP1) transcription by RB binding proteins. Oncogene (1998) 0.98
Retinoblastoma antioncogene is involved in the inhibition of myogenesis by polyomavirus large T antigen. Cell Growth Differ (1994) 0.97
Use of chemical modifications and site-directed mutagenesis to probe the functional role of thiol groups on the gamma subunit of Torpedo californica acetylcholine receptor. Biochemistry (1989) 0.95
Combined effect of socioeconomic status, viral hepatitis, and lifestyles on hepatocelluar carcinoma risk in Korea. Br J Cancer (2010) 0.95
The N-terminal region of E2F-1 is required for transcriptional activation of a new class of target promoter. J Biol Chem (1996) 0.95
J domain-independent regulation of the Rb family by polyomavirus large T antigen. J Virol (2000) 0.94
Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A. Mol Cell Biol (1998) 0.94
HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissue. Mol Cell Biol (2001) 0.94
Localization of the phosphorylations of polyomavirus large T antigen. J Virol (1987) 0.94
Genetic polymorphisms of cytochrome P450 19 and 1B1, alcohol use, and breast cancer risk in Korean women. Br J Cancer (2003) 0.92
The major site of tyrosine phosphorylation in polyomavirus middle T antigen is not required for transformation. J Virol (1984) 0.91
Altered conformational effects of phosphorylated lysine-rich histone (f-1) in f-1--deoxyribonucleic acid complexes. Circular dichroism and immunological studies. Biochemistry (1971) 0.91
Transactivation by the adenovirus E1A gene. Biochem Cell Biol (1988) 0.91
Ex vivo culture of chimeric antigen receptor T cells generates functional CD8+ T cells with effector and central memory-like phenotype. Gene Ther (2010) 0.89
Thiol-group modification of Torpedo californica acetylcholine receptor: subunit localization and effects on function. Biochemistry (1986) 0.89
Transcriptional factor HBP1 targets P16(INK4A), upregulating its expression and consequently is involved in Ras-induced premature senescence. Oncogene (2010) 0.88
Inhibition of cell migration by PITENINs: the role of ARF6. Oncogene (2011) 0.87
Phosphatidylinositol-3 kinase and growth regulation. Cold Spring Harb Symp Quant Biol (1992) 0.86
NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site. Biochemistry (2000) 0.86
Simplifying the measurement of gastric accommodation using SPECT. Neurogastroenterol Motil (2013) 0.84
NMR analysis of interactions of a phosphatidylinositol 3'-kinase SH2 domain with phosphotyrosine peptides reveals interdependence of major binding sites. Biochemistry (1996) 0.83
Transformation-defective polyoma middle T antigen mutants defective in PLCgamma, PI-3, or src kinase activation enhance ERK2 activation and promote retinoic acid-induced, cell differentiation like wild-type middle T. Exp Cell Res (1999) 0.83
A randomised, placebo-controlled trial comparing the effects of tapentadol and oxycodone on gastrointestinal and colonic transit in healthy humans. Aliment Pharmacol Ther (2012) 0.83
Electrical coupling and pacemaker activity in colonic smooth muscle. Am J Physiol (1988) 0.83
S-1 plus irinotecan and oxaliplatin for the first-line treatment of patients with metastatic colorectal cancer: a prospective phase II study and pharmacogenetic analysis. Br J Cancer (2013) 0.83
Epstein-Barr virus antibody level and gastric cancer risk in Korea: a nested case-control study. Br J Cancer (2009) 0.82
Detection of previous proximal venous thrombosis with Doppler ultrasonography and photoplethysmography. Arch Intern Med (1989) 0.81
Phosphoinositide kinase activity and transformation. Fed Proc (1986) 0.81
Genetic analysis of a phosphatidylinositol 3-kinase SH2 domain reveals determinants of specificity. Mol Cell Biol (1994) 0.80
Absence of retroviral vector-mediated transformation of gene-modified T cells after long-term engraftment in mice. Gene Ther (2008) 0.80
Expression of the E2F-1/DP-1 transcription factor in murine development. Cell Growth Differ (1996) 0.80
Magnesium: physiology, clinical disorders, and therapy. Ann Emerg Med (1981) 0.79
Mutations in polyomavirus middle T antigen affecting tumorigenesis. Virology (1989) 0.78
Proximal saphenous vein cutdown. Ann Emerg Med (1981) 0.77
Expression of SV40 and polyoma T antigens in E. coli. Gene Amplif Anal (1983) 0.75
Tyrosine phosphorylation in signal transduction. Cold Spring Harb Symp Quant Biol (1988) 0.75
[Introduction of primary nursing at the St. Luke's International Hospital]. Kango Tenbo (1988) 0.75
[Audit and evaluation of nursing records]. Kango Gijutsu (1983) 0.75
[Mother-child relations at delivery by cesarean section]. Josanpu Zasshi (1983) 0.75
[Process in the introduction of primary nursing at St. Luke's International Hospital]. Kango Tenbo (1988) 0.75
[Process of introduction of primary nursing at St. Luke's International Hospital (3)]. Kango Tenbo (1988) 0.75
Psychiatrists' hours by work setting. Psychiatr Serv (1996) 0.75
Effects of carboxymethylation by a purified Torpedo californica methylase on the functional properties of the acetylcholine receptor in reconstituted membranes. Arch Biochem Biophys (1985) 0.75
[Study on promotion of breast feeding - a research on the method of massage of the breast by Applebaum]. Kango Tenbo (1979) 0.75
Digoxin levels in prehospital sudden-death syndrome. J Clin Pharmacol (1987) 0.75
Myasthenia Gravis. Ann Emerg Med (1982) 0.75
[Introduction of primary nursing. A discussion]. Kango Tenbo (1988) 0.75