Published in Cell on October 21, 1994
Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J (1998) 7.17
Mitochondrial control of nuclear apoptosis. J Exp Med (1996) 5.01
BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc Natl Acad Sci U S A (1996) 4.20
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol Cell Biol (1999) 4.00
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med (1996) 4.00
A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EMBO J (1995) 3.70
Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. EMBO J (1996) 3.68
A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. EMBO J (1996) 3.57
Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis. Mol Cell Biol (1997) 3.39
Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol (1996) 2.97
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis. J Exp Med (1997) 2.83
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death Differ (2011) 2.66
Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am J Pathol (1998) 2.64
p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis. Mol Cell Biol (2000) 2.42
Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med (1996) 2.39
The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis. J Exp Med (1997) 2.33
Transitional B cells are the target of negative selection in the B cell compartment. J Exp Med (1995) 2.26
The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells. J Virol (1996) 2.25
Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells. Mol Cell Biol (1996) 2.24
Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc Natl Acad Sci U S A (1996) 2.21
Fas ligation induces apoptosis of CD40-activated human B lymphocytes. J Exp Med (1995) 2.19
Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death. J Exp Med (1996) 1.98
Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2. EMBO J (1997) 1.83
CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival. Genes Dev (1997) 1.83
Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation. Proc Natl Acad Sci U S A (1997) 1.78
Bax- and Bak-induced cell death in the fission yeast Schizosaccharomyces pombe. Mol Biol Cell (1997) 1.75
E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk. J Cell Biol (1998) 1.75
Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest (1998) 1.73
Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol Cell Biol (1998) 1.70
Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice. J Cell Biol (2002) 1.69
The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4. EMBO J (1998) 1.66
Cisplatin nephrotoxicity: molecular mechanisms. Cancer Ther (2003) 1.61
Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo. EMBO J (1995) 1.60
Acupuncture with reinforcing and reducing twirling manipulation inhibits hippocampal neuronal apoptosis in spontaneously hypertensive rats. Neural Regen Res (2017) 1.39
Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis. Mol Cell Biol (1999) 1.39
Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts. J Exp Med (1996) 1.35
DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective. EMBO J (1995) 1.33
5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins. Br J Cancer (1998) 1.32
p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement. J Exp Med (1996) 1.31
Differences in apoptotic susceptibility of cytotrophoblasts and syncytiotrophoblasts in normal pregnancy to those complicated with preeclampsia and intrauterine growth restriction. Am J Pathol (2003) 1.29
Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade. Mol Cell Biol (1997) 1.26
Strategies for manipulating the p53 pathway in the treatment of human cancer. Biochem J (2000) 1.26
Apoptosis by a cytosolic extract from Fas-activated cells. EMBO J (1995) 1.21
Caspase cleavage enhances the apoptosis-inducing effects of BAD. Mol Cell Biol (2001) 1.21
Bax-induced cytochrome c release from mitochondria depends on alpha-helices-5 and -6. Biochem J (2004) 1.19
The ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type. J Virol (1997) 1.19
The control of hematopoiesis and leukemia: from basic biology to the clinic. Proc Natl Acad Sci U S A (1996) 1.18
Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis. Mol Cell Biol (1996) 1.16
Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant. J Exp Med (1998) 1.13
BAX enhances paclitaxel-induced apoptosis through a p53-independent pathway. Proc Natl Acad Sci U S A (1996) 1.13
Differential suppression by protease inhibitors and cytokines of apoptosis induced by wild-type p53 and cytotoxic agents. Proc Natl Acad Sci U S A (1996) 1.13
Reduced expression of BAX is associated with poor prognosis in patients with epithelial ovarian cancer: a multifactorial analysis of TP53, p21, BAX and BCL-2. Br J Cancer (2001) 1.08
Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells. Mol Cell Biol (2002) 1.04
Control of cell cycle entry and apoptosis in B lymphocytes infected by Epstein-Barr virus. J Virol (1999) 1.04
Caspase-dependent Cdk activity is a requisite effector of apoptotic death events. J Cell Biol (2000) 1.01
Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin. Am J Pathol (1997) 1.00
Evidence for a G2 checkpoint in p53-independent apoptosis induction by X-irradiation. Mol Cell Biol (1995) 0.99
Activation of membrane-associated procaspase-3 is regulated by Bcl-2. J Cell Biol (1999) 0.98
Identification of a novel antiapoptotic protein, GAM-1, encoded by the CELO adenovirus. J Virol (1997) 0.96
Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: a selective effect on Bcl-XL expression. Immunology (1996) 0.96
A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicity. Proc Natl Acad Sci U S A (1995) 0.94
Proposed mechanism for the stabilization of nuclear receptor DNA binding via protein dimerization. Mol Cell Biol (1997) 0.94
Regulation of Bcl-xL expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor. Proc Natl Acad Sci U S A (1997) 0.93
Proteasomal degradation of human peptidyl prolyl isomerase pin1-pointing phospho Bcl2 toward dephosphorylation. Neoplasia (2002) 0.91
Identification of genes induced by factor deprivation in hematopoietic cells undergoing apoptosis using gene-trap mutagenesis and site-specific recombination. Proc Natl Acad Sci U S A (1996) 0.91
A portrait of the Bcl-2 protein family: life, death, and the whole picture. J Clin Immunol (1999) 0.90
Distinct sites of action of Bcl-2 and Bcl-xL in the ceramide pathway of apoptosis. Biochem J (1998) 0.90
Expression of p53, Bcl-2 and Bax in cisplatin-induced apoptosis in testicular germ cell tumour cell lines. Br J Cancer (1998) 0.90
Immunodetection of apoptosis-regulating proteins in lymphomas from patients with and without human immunodeficiency virus infection. Am J Pathol (1996) 0.89
The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes. Immunology (2003) 0.88
Prognostic significance of the bcl-2 apoptotic family of proteins in primary and recurrent cervical cancer. Br J Cancer (1998) 0.87
Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death. BMC Neurosci (2003) 0.87
Quantitative expression analysis and prognostic significance of the BCL2-associated X gene in nasopharyngeal carcinoma: a retrospective cohort study. BMC Cancer (2013) 0.87
Characterization of a novel interaction between Bcl-2 members Diva and Harakiri. PLoS One (2010) 0.86
Loss of Hus1 sensitizes cells to etoposide-induced apoptosis by regulating BH3-only proteins. Oncogene (2008) 0.86
Possible roles of proinflammatory and chemoattractive cytokines produced by human fetal membrane cells in the pathology of adverse pregnancy outcomes associated with influenza virus infection. Mediators Inflamm (2012) 0.86
Cif (Cytochrome c efflux-inducing factor) activity is regulated by Bcl-2 and caspases and correlates with the activation of Bid. Mol Cell Biol (1999) 0.86
Chemotherapy drug response in ovarian cancer cells strictly depends on a cathepsin D-Bax activation loop. J Cell Mol Med (2008) 0.86
Molecular steps of cell suicide: an insight into immune senescence. J Clin Immunol (2000) 0.85
Anti-oestrogen resistant human breast cancer cell lines are more sensitive towards treatment with the vitamin D analogue EB1089 than parent MCF-7 cells. Br J Cancer (2001) 0.82
The murine C'-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells. Mol Cell Biol (1997) 0.82
Differential effect of vinorelbine versus paclitaxel on ERK2 kinase activity during apoptosis in MCF-7 cells. Br J Cancer (2001) 0.81
Chemotherapy cytotoxicity of human MCF-7 and MDA-MB 231 breast cancer cells is altered by osteoblast-derived growth factors. Mol Med (1999) 0.81
Intrinsic order and disorder in the bcl-2 member harakiri: insights into its proapoptotic activity. PLoS One (2011) 0.80
A possible role of multidrug resistance-associated protein (MRP) in basic fibroblast growth factor secretion by AIDS-associated Kaposi's sarcoma cells: a survival molecule? J Clin Immunol (1998) 0.79
Interrelationships between apoptosis and fertility in bull sperm. J Reprod Dev (2012) 0.78
IL-7 sensitizes human pre-B cells but not pro-B cells to Fas/APO-1 (CD95)-mediated apoptosis. Clin Exp Immunol (1997) 0.77
Erratum to: Immune maintenance in glaucoma: boosting the body's own neuroprotective potential. J Ocul Biol Dis Infor (2009) 0.77
Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells. Toxins (Basel) (2016) 0.77
Identification of a novel antiapoptotic functional domain in simian virus 40 large T antigen. J Virol (1997) 0.77
Immune maintenance in glaucoma: boosting the body's own neuroprotective potential. J Ocul Biol Dis Infor (2009) 0.77
Apoptotic activities in soft tissue sarcoma: immunohistochemical study and their association with tumour characteristics. Malays J Med Sci (2013) 0.77
Growth arrest and apoptosis of human hepatocellular carcinoma cells induced by hexamethylene bisacetamide. World J Gastroenterol (2004) 0.77
Cell fusion to study nuclear-cytoplasmic interactions in endothelial cell apoptosis. Am J Pathol (1996) 0.77
Effects of p53 on aldosterone-induced mesangial cell apoptosis in vivo and in vitro. Mol Med Rep (2016) 0.76
Looking beneath the surface: the cell death pathway of Fas/APO-1 (CD95). Mol Med (1996) 0.75
Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell (1994) 4.32
DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell (1994) 4.22
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell (1994) 3.86
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science (2001) 23.42
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell (1993) 20.72
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature (1990) 14.46
BCL-2 family members and the mitochondria in apoptosis. Genes Dev (1999) 13.52
Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell (1993) 10.83
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) Cell (1996) 10.83
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol Cell (2001) 9.33
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell (2000) 8.95
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell (1995) 8.75
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c. Genes Dev (2000) 8.35
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell (1991) 8.13
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell (1985) 7.29
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell (1993) 7.25
Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science (1995) 6.84
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature (1994) 6.69
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell (1989) 6.66
Altered Hox expression and segmental identity in Mll-mutant mice. Nature (1995) 6.60
BCL-2 family: regulators of cell death. Annu Rev Immunol (1998) 6.41
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature (1999) 6.37
Cell death in development. Cell (1999) 6.01
BID: a novel BH3 domain-only death agonist. Genes Dev (1996) 5.90
Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J (1998) 5.78
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci U S A (1991) 5.50
Isolation of single-copy human genes from a library of yeast artificial chromosome clones. Science (1989) 5.29
Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol (1990) 5.26
Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood (1996) 5.13
Clustered arrangement of immunoglobulin lambda constant region genes in man. Nature (1981) 4.87
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem (1999) 4.56
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci U S A (1995) 4.22
BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc Natl Acad Sci U S A (1996) 4.20
Regulated targeting of BAX to mitochondria. J Cell Biol (1998) 4.17
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18). Nature (1991) 4.06
BAX is required for neuronal death after trophic factor deprivation and during development. Neuron (1996) 4.02
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol Cell Biol (1999) 4.00
Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. EMBO J (1988) 3.77
Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells. Proc Natl Acad Sci U S A (1981) 3.73
Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc Natl Acad Sci U S A (1997) 3.66
Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells. Nature (1981) 3.64
BAX-dependent transport of cytochrome c reconstituted in pure liposomes. Nat Cell Biol (2000) 3.53
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol Cell (1999) 3.46
Prevention of lymphocyte cell death in sepsis improves survival in mice. Proc Natl Acad Sci U S A (1999) 3.35
Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes. J Immunol (1993) 3.28
Expression of interleukin 2 receptors on activated human B cells. J Exp Med (1984) 3.27
Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence. J Biol Chem (1993) 3.21
Mcl-1 deficiency results in peri-implantation embryonic lethality. Genes Dev (2000) 3.21
Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners. Proc Natl Acad Sci U S A (1987) 3.18
p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc Natl Acad Sci U S A (2001) 3.11
Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature (1997) 3.10
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis. Science (2000) 3.06
Immunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasms. N Engl J Med (1983) 2.96
Bcl-XL and Bcl-2 repress a common pathway of cell death. J Exp Med (1995) 2.94
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J Immunol (1999) 2.92
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. J Clin Invest (1983) 2.91
Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J Neurosci (1998) 2.80
Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals. Nat Genet (2001) 2.79
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. Proc Natl Acad Sci U S A (1999) 2.76
Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Proc Natl Acad Sci U S A (1983) 2.73
MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci U S A (1998) 2.65
A uniform deleting element mediates the loss of kappa genes in human B cells. Nature (1985) 2.65
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science (1991) 2.64
Bcl-2 and Bax function independently to regulate cell death. Nat Genet (1997) 2.64
bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc Natl Acad Sci U S A (1997) 2.59
MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol Cell Biol (2001) 2.58
Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. J Biol Chem (1999) 2.52
Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists. Cell (1999) 2.51
A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c. EMBO J (2001) 2.44
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease. Proc Natl Acad Sci U S A (1988) 2.42
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity (1994) 2.40
Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells. J Clin Invest (1987) 2.39
The apoptotic v-cyclin-CDK6 complex phosphorylates and inactivates Bcl-2. Nat Cell Biol (2000) 2.36
Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics. Blood (1985) 2.35
Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways. Nat Med (1998) 2.29
Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors. J Biol Chem (1996) 2.26
Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population. Mol Cell Biol (1990) 2.25
The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. Mol Cell Biol (1989) 2.24
BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity. J Biol Chem (1997) 2.23
Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nat Med (1997) 2.19
Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. Proc Natl Acad Sci U S A (1996) 2.19
Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes. EMBO J (1994) 2.16
Bcl-2 gene family in the nervous system. Annu Rev Neurosci (1997) 2.16
Defects in yolk sac hematopoiesis in Mll-null embryos. Blood (1997) 2.06
Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Mol Cell Biol (1998) 2.05
Mouse models of cell death. Nat Genet (2001) 2.01
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis. Mol Cell Biol (2001) 1.96
Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3. Proc Natl Acad Sci U S A (1989) 1.95
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J Cell Biol (1997) 1.89
Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus. J Biol Chem (1994) 1.87
Hox11 controls the genesis of the spleen. Nature (1994) 1.81
BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia. Proc Natl Acad Sci U S A (2001) 1.74
A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter. Mol Cell Biol (1993) 1.73
Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product. Proc Natl Acad Sci U S A (1993) 1.73
Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol Cell Biol (1998) 1.70
Bcl-2 maintains B cell memory. Nature (1991) 1.68
Rearrangements of genes for the antigen receptor on T cells as markers of lineage and clonality in human lymphoid neoplasms. N Engl J Med (1985) 1.65
Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency. Nat Genet (1999) 1.64
A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast. J Cell Biol (2001) 1.63
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2001) 1.62
Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma. Mol Cell Biol (1992) 1.62
Hematopoietic malignancies demonstrate loss-of-function mutations of BAX. Blood (1998) 1.61