Selective enzyme induction in a nerve growth factor-responsive pheochromocytoma cell line (PC 12).

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 81091)

Published in Brain Res on October 06, 1978

Authors

D H Edgar, H Thoenen

Articles citing this

Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor. J Cell Biol (1983) 1.96

Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP. Proc Natl Acad Sci U S A (1987) 1.81

Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor. J Cell Biol (1981) 1.72

Regulation of the differentiation of PC12 pheochromocytoma cells. Environ Health Perspect (1989) 1.62

Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists. Mol Cell Biol (1985) 1.57

Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Mol Cell Biol (1987) 1.42

Changes in the organization of the neuritic cytoskeleton during nerve growth factor-activated differentiation of PC12 cells: a serial electron microscopic study of the development and control of neurite shape. J Cell Biol (1986) 1.08

Identification of cDNA clones coding for rat tyrosine hydroxylase antigen. Proc Natl Acad Sci U S A (1982) 1.04

Regulation of nerve growth factor receptor gene expression by nerve growth factor in the developing peripheral nervous system. J Cell Biol (1991) 1.01

Identification and cell type specificity of the tyrosine hydroxylase gene promoter. Nucleic Acids Res (1987) 0.95

Evidence for nerve growth factor-mediated paracrine effects in human epidermis. J Cell Biol (1991) 0.92

Isolated plasma membranes regulate neurotransmitter expression and facilitate effects of a soluble brain cholinergic factor. Proc Natl Acad Sci U S A (1986) 0.90

Solubilization of a membrane factor that stimulates levels of substance P and choline acetyltransferase in sympathetic neurons. Proc Natl Acad Sci U S A (1987) 0.86

Translation of tyrosine hydroxylase from poly(A)-mRNA in pheochromocytoma cells is enhanced by dexamethasone. Proc Natl Acad Sci U S A (1981) 0.83

Articles by these authors

(truncated to the top 100)

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A (1995) 5.25

Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 4.85

Physiology of nerve growth factor. Physiol Rev (1980) 4.58

Molecular cloning and expression of brain-derived neurotrophic factor. Nature (1989) 3.90

Purification of a new neurotrophic factor from mammalian brain. EMBO J (1982) 3.68

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature (1992) 3.39

The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J (1984) 3.39

Neurotrophin-evoked rapid excitation through TrkB receptors. Nature (1999) 3.11

The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature (1988) 2.47

Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol (1987) 2.40

Increase in tyrosine hydroxylase activity after reserpine administration. J Pharmacol Exp Ther (1969) 2.32

Disruption of the CNTF gene results in motor neuron degeneration. Nature (1993) 2.22

Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proc Natl Acad Sci U S A (1992) 2.19

Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci U S A (1983) 2.17

Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci U S A (1996) 2.10

Some pharmacological actions of the beta-adrenolytic agent Ro 3-3528 (6,7-dimethyl-alpha-[(isopropylamino) methyl]-2-benzofuranmethanol Hydrochloride). Angiologica (1967) 2.10

A role for BDNF in mechanosensation. Nat Neurosci (1998) 2.08

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature (1990) 2.06

An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia (1968) 1.98

Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci U S A (1997) 1.96

Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proc Natl Acad Sci U S A (1971) 1.96

Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J (1985) 1.93

Relation between the rate of stimulation and the quantity of noradrenaline liberated from sympathetic nerve endings in the isolated perfused spleen of the cat. J Physiol (1965) 1.92

Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol (1992) 1.87

Dual site of action of phenoxybenzamine in the cat's spleen; blockade of alpha-adrenergic receptors and inhibition of re-uptake of neurally released norepinephrine. Experientia (1964) 1.83

Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci (1985) 1.82

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature (1990) 1.80

Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci U S A (1991) 1.79

NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res (1983) 1.77

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor. Nature (1987) 1.76

Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur J Neurosci (1995) 1.72

Increased tyrosine hydroxylase activity after drug-induced alteration of sympathetic transmission. Nature (1969) 1.72

Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J (1984) 1.71

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature (1993) 1.71

The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport (1993) 1.70

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A (1987) 1.70

Sensory neurons in culture: changing requirements for survival factors during embryonic development. Proc Natl Acad Sci U S A (1980) 1.69

Central adrenergic neurones and the initiation and development of experimental hypertension. Experientia (1972) 1.67

Trans-synaptic induction of adrenal tyrosine hydroxylase. J Pharmacol Exp Ther (1969) 1.67

Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecum. Gut (1999) 1.66

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci (1986) 1.64

Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol (1992) 1.64

Electronmicroscopic localization of 5-hydroxydopamine (3,4,5-trihydroxy-phenyl-ethylamine), a new 'false' sympathetic transmitter. Experientia (1967) 1.61

Nerve growth factor in mouse and rat serum: correlation between bioassay and radioimmunoassay determinations. Proc Natl Acad Sci U S A (1978) 1.59

Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci (1994) 1.57

Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol (1985) 1.57

Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc Natl Acad Sci U S A (1997) 1.55

Potentiation by tetraethylammonium of the response of the cat spleen to postganglionic sympathetic nerve stimulation. J Pharmacol Exp Ther (1967) 1.54

Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci (1990) 1.53

Specificity of the retrograde axonal transport of nerve growth factor. Brain Res (1974) 1.52

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J Cell Biol (1992) 1.51

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci U S A (1978) 1.50

Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat. Ann Neurol (1994) 1.49

Purification of nerve growth factor antibodies by affinity chromatography. J Neurochem (1976) 1.49

Chemical sympathectomy of the cat with 6-hydroxydopamine. J Pharmacol Exp Ther (1969) 1.46

Comparative studies on the effect of the nerve growth factor on sympathetic ganglia and adrenal medulla in newborn rats. Brain Res (1972) 1.44

Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons. Brain Res (1975) 1.40

Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity. J Neurobiol (1994) 1.40

Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. J Neurosci (1992) 1.37

Relationship between NGF-mediated volume increase and "priming effect" in fast and slow reacting clones of PC12 pheochromocytoma cells. Role of cAMP. Exp Cell Res (1983) 1.36

Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation. Neuron (1996) 1.36

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron (1996) 1.35

Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor. Mol Cell Neurosci (1997) 1.33

The physiological function of nerve growth factor in the central nervous system: comparison with the periphery. Rev Physiol Biochem Pharmacol (1987) 1.33

Adrenal tyrosine hydroxylase: compensatory increase in activity after chemical sympathectomy. Science (1969) 1.33

Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain. J Cell Biol (1991) 1.30

Mechanism of amphetamine accumulation in the isolated perfused heart of the rat. J Pharm Pharmacol (1968) 1.30

Cellular localization of nerve growth factor synthesis by in situ hybridization. EMBO J (1987) 1.28

[Research on the problem of a cholinergic link in postganglionic sympathetic transmission]. Helv Physiol Pharmacol Acta (1966) 1.28

Nerve growth factor (NGF) in the rat CNS: absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra. Brain Res (1979) 1.28

GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron (1996) 1.28

Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport. J Cell Biol (1979) 1.28

Induction of tyrosine hydroxylase in peripheral and central adrenergic neurones by cold-exposure of rats. Nature (1970) 1.27

Inhibition of trans-synaptically increased tyrosine hydroxylase activity by cycloheximide and actinomycin D. Mol Pharmacol (1969) 1.27

Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts. J Biol Chem (1988) 1.27

In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells. EMBO J (1987) 1.25

GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (1995) 1.25

Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule-binding protein. Nature (1989) 1.25

Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos. Proc Natl Acad Sci U S A (1990) 1.24

Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons. Mol Cell Neurosci (1996) 1.23

Brain-derived neurotrophic factor messenger RNA is expressed in the septum, hypothalamus and in adrenergic brain stem nuclei of adult rat brain and is increased by osmotic stimulation in the paraventricular nucleus. Neuroscience (1995) 1.23

New factor released by cultured glioma cells supporting survival and growth of sensory neurones. Nature (1978) 1.23

The response of chick sensory neurons to brain-derived neurotrophic factor. J Neurosci (1986) 1.23

Neurotrophic factors. Science (1985) 1.23

Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies. J Cell Biol (1988) 1.22

Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways. EMBO J (2001) 1.20

Expression of neurotrophins in skeletal muscle: quantitative comparison and significance for motoneuron survival and maintenance of function. J Neurosci Res (1995) 1.20

Nerve growth factor-mediated selective induction of ornithine decarboxylase in rat pheochromocytoma; a cyclic AMP-independent process. FEBS Lett (1978) 1.19

Liberation of p-hydroxynorephedrine from cat spleen by sympathetic nerve stimulation after pretreatment with amphetamine. Life Sci (1966) 1.19

Subpopulations of cultured chick sympathetic neurones differ in their requirements for survival factors. Nature (1981) 1.19

Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity. Eur J Neurosci (1993) 1.19

Comparison between the time course of changes in nerve growth factor protein levels and those of its messenger RNA in the cultured rat iris. J Biol Chem (1986) 1.18

Characterization of TrkB receptor-mediated signaling pathways in rat cerebellar granule neurons: involvement of protein kinase C in neuronal survival. J Neurochem (1995) 1.18

Selective binding, uptake, and retrograde transport of tetanus toxin by nerve terminals in the rat iris. An electron microscope study using colloidal gold as a tracer. J Cell Biol (1978) 1.18

Nerve growth factor-mediated enzyme induction in primary cultures of bovine adrenal chromaffin cells: specificity and level of regulation. J Neurosci (1984) 1.18

Ciliary neurotrophic factor. J Neurobiol (1994) 1.17

Nerve growth factor induces volume increase and enhances tyrosine hydroxylase synthesis in chemically axotomized sympathetic ganglia of newborn rats. Proc Natl Acad Sci U S A (1975) 1.17

Interaction of phenoxybenzamine with guanethidine and bretylium at the sympathetic nerve endings of the isolated perfused spleen of the cat. J Pharmacol Exp Ther (1966) 1.17