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H Thoenen

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A 1995 5.25
2 Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol 1968 4.85
3 Physiology of nerve growth factor. Physiol Rev 1980 4.58
4 Molecular cloning and expression of brain-derived neurotrophic factor. Nature 1989 3.90
5 Purification of a new neurotrophic factor from mammalian brain. EMBO J 1982 3.68
6 Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 1992 3.39
7 The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J 1984 3.39
8 Neurotrophin-evoked rapid excitation through TrkB receptors. Nature 1999 3.11
9 The retrograde axonal transport of nerve growth factor. Brain Res 1974 2.60
10 Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J 1990 2.54
11 Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature 1988 2.47
12 Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol 1987 2.40
13 Increase in tyrosine hydroxylase activity after reserpine administration. J Pharmacol Exp Ther 1969 2.32
14 Disruption of the CNTF gene results in motor neuron degeneration. Nature 1993 2.22
15 Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proc Natl Acad Sci U S A 1992 2.19
16 Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci U S A 1983 2.17
17 Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci U S A 1996 2.10
18 Some pharmacological actions of the beta-adrenolytic agent Ro 3-3528 (6,7-dimethyl-alpha-[(isopropylamino) methyl]-2-benzofuranmethanol Hydrochloride). Angiologica 1967 2.10
19 A role for BDNF in mechanosensation. Nat Neurosci 1998 2.08
20 Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 1990 2.06
21 An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia 1968 1.98
22 Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci U S A 1997 1.96
23 Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proc Natl Acad Sci U S A 1971 1.96
24 Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J 1985 1.93
25 Relation between the rate of stimulation and the quantity of noradrenaline liberated from sympathetic nerve endings in the isolated perfused spleen of the cat. J Physiol 1965 1.92
26 Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol 1992 1.87
27 Dual site of action of phenoxybenzamine in the cat's spleen; blockade of alpha-adrenergic receptors and inhibition of re-uptake of neurally released norepinephrine. Experientia 1964 1.83
28 Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci 1985 1.82
29 Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature 1990 1.80
30 Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci U S A 1991 1.79
31 NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res 1983 1.77
32 Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor. Nature 1987 1.76
33 Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur J Neurosci 1995 1.72
34 Increased tyrosine hydroxylase activity after drug-induced alteration of sympathetic transmission. Nature 1969 1.72
35 Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J 1984 1.71
36 Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 1993 1.71
37 The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport 1993 1.70
38 Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A 1987 1.70
39 Sensory neurons in culture: changing requirements for survival factors during embryonic development. Proc Natl Acad Sci U S A 1980 1.69
40 Central adrenergic neurones and the initiation and development of experimental hypertension. Experientia 1972 1.67
41 Trans-synaptic induction of adrenal tyrosine hydroxylase. J Pharmacol Exp Ther 1969 1.67
42 Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci 1986 1.64
43 Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol 1992 1.64
44 Electronmicroscopic localization of 5-hydroxydopamine (3,4,5-trihydroxy-phenyl-ethylamine), a new 'false' sympathetic transmitter. Experientia 1967 1.61
45 Nerve growth factor in mouse and rat serum: correlation between bioassay and radioimmunoassay determinations. Proc Natl Acad Sci U S A 1978 1.59
46 Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci 1994 1.57
47 Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol 1985 1.57
48 Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc Natl Acad Sci U S A 1997 1.55
49 Potentiation by tetraethylammonium of the response of the cat spleen to postganglionic sympathetic nerve stimulation. J Pharmacol Exp Ther 1967 1.54
50 Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci 1990 1.53
51 Specificity of the retrograde axonal transport of nerve growth factor. Brain Res 1974 1.52
52 Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J Cell Biol 1992 1.51
53 Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci U S A 1978 1.50
54 Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat. Ann Neurol 1994 1.49
55 Purification of nerve growth factor antibodies by affinity chromatography. J Neurochem 1976 1.49
56 Chemical sympathectomy of the cat with 6-hydroxydopamine. J Pharmacol Exp Ther 1969 1.46
57 Comparative studies on the effect of the nerve growth factor on sympathetic ganglia and adrenal medulla in newborn rats. Brain Res 1972 1.44
58 Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons. Brain Res 1975 1.40
59 Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity. J Neurobiol 1994 1.40
60 Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. J Neurosci 1992 1.37
61 Relationship between NGF-mediated volume increase and "priming effect" in fast and slow reacting clones of PC12 pheochromocytoma cells. Role of cAMP. Exp Cell Res 1983 1.36
62 Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation. Neuron 1996 1.36
63 Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron 1996 1.35
64 Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor. Mol Cell Neurosci 1997 1.33
65 The physiological function of nerve growth factor in the central nervous system: comparison with the periphery. Rev Physiol Biochem Pharmacol 1987 1.33
66 Adrenal tyrosine hydroxylase: compensatory increase in activity after chemical sympathectomy. Science 1969 1.33
67 Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain. J Cell Biol 1991 1.30
68 Mechanism of amphetamine accumulation in the isolated perfused heart of the rat. J Pharm Pharmacol 1968 1.30
69 Cellular localization of nerve growth factor synthesis by in situ hybridization. EMBO J 1987 1.28
70 [Research on the problem of a cholinergic link in postganglionic sympathetic transmission]. Helv Physiol Pharmacol Acta 1966 1.28
71 GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron 1996 1.28
72 Nerve growth factor (NGF) in the rat CNS: absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra. Brain Res 1979 1.28
73 Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport. J Cell Biol 1979 1.28
74 Induction of tyrosine hydroxylase in peripheral and central adrenergic neurones by cold-exposure of rats. Nature 1970 1.27
75 Inhibition of trans-synaptically increased tyrosine hydroxylase activity by cycloheximide and actinomycin D. Mol Pharmacol 1969 1.27
76 Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts. J Biol Chem 1988 1.27
77 In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells. EMBO J 1987 1.25
78 GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development 1995 1.25
79 Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule-binding protein. Nature 1989 1.25
80 Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos. Proc Natl Acad Sci U S A 1990 1.24
81 Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons. Mol Cell Neurosci 1996 1.23
82 Neurotrophic factors. Science 1985 1.23
83 New factor released by cultured glioma cells supporting survival and growth of sensory neurones. Nature 1978 1.23
84 Brain-derived neurotrophic factor messenger RNA is expressed in the septum, hypothalamus and in adrenergic brain stem nuclei of adult rat brain and is increased by osmotic stimulation in the paraventricular nucleus. Neuroscience 1995 1.23
85 The response of chick sensory neurons to brain-derived neurotrophic factor. J Neurosci 1986 1.23
86 Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies. J Cell Biol 1988 1.22
87 Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways. EMBO J 2001 1.20
88 Expression of neurotrophins in skeletal muscle: quantitative comparison and significance for motoneuron survival and maintenance of function. J Neurosci Res 1995 1.20
89 Nerve growth factor-mediated selective induction of ornithine decarboxylase in rat pheochromocytoma; a cyclic AMP-independent process. FEBS Lett 1978 1.19
90 Liberation of p-hydroxynorephedrine from cat spleen by sympathetic nerve stimulation after pretreatment with amphetamine. Life Sci 1966 1.19
91 Subpopulations of cultured chick sympathetic neurones differ in their requirements for survival factors. Nature 1981 1.19
92 Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity. Eur J Neurosci 1993 1.19
93 Characterization of TrkB receptor-mediated signaling pathways in rat cerebellar granule neurons: involvement of protein kinase C in neuronal survival. J Neurochem 1995 1.18
94 Comparison between the time course of changes in nerve growth factor protein levels and those of its messenger RNA in the cultured rat iris. J Biol Chem 1986 1.18
95 Selective binding, uptake, and retrograde transport of tetanus toxin by nerve terminals in the rat iris. An electron microscope study using colloidal gold as a tracer. J Cell Biol 1978 1.18
96 Nerve growth factor-mediated enzyme induction in primary cultures of bovine adrenal chromaffin cells: specificity and level of regulation. J Neurosci 1984 1.18
97 Ciliary neurotrophic factor. J Neurobiol 1994 1.17
98 Nerve growth factor induces volume increase and enhances tyrosine hydroxylase synthesis in chemically axotomized sympathetic ganglia of newborn rats. Proc Natl Acad Sci U S A 1975 1.17
99 Specificity of retrograde transport of nerve growth factor (NGF) in sensory neurons: a biochemical and morphological study. Brain Res 1975 1.17
100 Interaction of phenoxybenzamine with guanethidine and bretylium at the sympathetic nerve endings of the isolated perfused spleen of the cat. J Pharmacol Exp Ther 1966 1.17
101 Various types of amine-storing vesicles in peripheral adrenergic nerve terminals. Experientia 1968 1.17
102 Are there differences between the secretion characteristics of NGF and BDNF? Implications for the modulatory role of neurotrophins in activity-dependent neuronal plasticity. Microsc Res Tech 1999 1.14
103 Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat hippocampus. J Neurosci 1993 1.14
104 New neurotrophic factors. Annu Rev Physiol 1983 1.13
105 Neurotrophin-6 is a new member of the nerve growth factor family. Nature 1994 1.13
106 Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: possible relationship to the regulation of nerve growth factor synthesis. J Cell Biol 1990 1.13
107 Molecular cloning of bovine and chick nerve growth factor (NGF): delineation of conserved and unconserved domains and their relationship to the biological activity and antigenicity of NGF. EMBO J 1986 1.13
108 Cell-type-specific regulation of nerve growth factor (NGF) synthesis in non-neuronal cells: comparison of Schwann cells with other cell types. J Neurosci 1991 1.13
109 The pharmacology of 6-hydroxydopamine. Annu Rev Pharmacol 1973 1.11
110 Trans-synaptic enzyme induction. Life Sci 1974 1.11
111 Target cells, biological effects, and mechanism of action of nerve growth factor and its antibodies. Annu Rev Pharmacol Toxicol 1981 1.10
112 Biological importance of retrograde axonal transport of nerve growth factor in adrenergic neurons. Brain Res 1975 1.09
113 Gene transfer through the blood-nerve barrier: NGF-engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis. Nat Med 1995 1.08
114 Properties of the nerve growth factor receptor of a clonal line of rat pheochromocytoma (PC12) cells. Exp Cell Res 1979 1.08
115 Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J Neurosci Res 1993 1.08
116 Regulation of nerve growth factor synthesis and release in organ cultures of rat iris. J Cell Biol 1984 1.08
117 Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF. Curr Biol 1996 1.08
118 Treatment with 6-hydroxydopamine and colchicine decreases nerve growth factor levels in sympathetic ganglia and increases them in the corresponding target tissues. J Neurosci 1985 1.07
119 Immunocytochemical localization of nerve growth factor (NGF) in the submandibular gland of adult mice by light and electron microscopy. Cell Tissue Res 1976 1.06
120 Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation. J Neurosci 1987 1.06
121 Retrograde axonal transport of specific macromolecules as a tool for characterizing nerve terminal membranes. J Neurobiol 1979 1.06
122 Production of specific antisera and monoclonal antibodies to choline acetyltransferase: characterization and use for identification of cholinergic neurons. EMBO J 1982 1.05
123 Retrograde axonal transport of nerve growth factor: specificity and biological importance. Brain Res 1975 1.05
124 Experimental hypertension of the rat: reciprocal changes of norepinephrine turnover in heart and brain-stem. Naunyn Schmiedebergs Arch Pharmakol 1971 1.05
125 Role of gangliosides in the uptake and retrograde axonal transport of cholera and tetanus toxin as compared to nerve growth factor and wheat germ agglutinin. Brain Res 1977 1.05
126 Developmental changes of nerve growth factor levels in sympathetic ganglia and their target organs. Dev Biol 1988 1.05
127 Brain-derived neurotrophic factor reversed experience-dependent synaptic modifications in kitten visual cortex. Eur J Neurosci 1996 1.04
128 Selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase by nerve growth factor: comparison between adrenal medulla and sympathetic ganglia of adult and newborn rats. Brain Res 1977 1.04
129 Autocrine-paracrine regulation of hippocampal neuron survival by IGF-1 and the neurotrophins BDNF, NT-3 and NT-4. Eur J Neurosci 1996 1.04
130 Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat. Metab Brain Dis 1997 1.04
131 Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture. Dev Biol 1986 1.04
132 Quantitative demonstration of the retrograde axonal transport of endogenous nerve growth factor. Neurosci Lett 1983 1.04
133 Selective enzyme induction in a nerve growth factor-responsive pheochromocytoma cell line (PC 12). Brain Res 1978 1.04
134 Selective trans-synaptic migration of tetanus toxin after retrograde axonal transport in peripheral sympathetic nerves: a comparison with nerve growth factor. Brain Res 1977 1.03
135 Adrenergic transmitter changes and response to sympathetic nerve stimulation after differing pretreatment with alpha-methyldopa. Br J Pharmacol Chemother 1967 1.03
136 Time course of the development of enzymes involved in the synthesis of norepinephrine in the superior cervical ganglion of the rat from birth to adult life. Brain Res 1972 1.02
137 The purification of nerve growth factor from bovine seminal plasma. Biochemical characterization and partial amino acid sequence. J Biol Chem 1982 1.02
138 Developmental potential of quail dorsal root ganglion cells analyzed in vitro and in vivo. J Neurosci 1986 1.00
139 Effect of ciliary neurotrophic factor (CNTF) on motoneuron survival. J Cell Sci Suppl 1991 1.00
140 Neuronally mediated enzyme induction in adrenergic neurons and adrenal chromaffin cells. Biochem Soc Symp 1972 0.98
141 Calbindin-D28k fails to protect hippocampal neurons against ischemia in spite of its cytoplasmic calcium buffering properties: evidence from calbindin-D28k knockout mice. Neuroscience 1998 0.98
142 Induction of tyrosine hydroxylase by nerve growth factor and by elevated K+ concentrations in cultures of dissociated sympathetic neurons. J Neurosci 1982 0.98
143 Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice. J Neurosci 1997 0.98
144 Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. J Neurosci 1996 0.97
145 Ciliary neurotrophic factor enhances the rate of oligodendrocyte generation. Mol Cell Neurosci 1996 0.97
146 Two-site enzyme immunoassay for nerve growth factor. Methods Enzymol 1987 0.97
147 TrkA tyrosine residues involved in NGF-induced neurite outgrowth of PC12 cells. Eur J Neurosci 1995 0.97
148 Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression. Development 1990 0.96
149 Cation dependence of the noradrenaline-releasing action of tyramine. Eur J Pharmacol 1969 0.96
150 Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia. Brain Res 1978 0.96
151 The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age. Dev Biol 1989 0.96
152 Recent developments on the ultrastructural aspect of adrenergic nerve endings in various experimental conditions. Prog Brain Res 1969 0.96
153 Efficient generation of chimaeric mice using embryonic stem cells after long-term culture in the presence of ciliary neurotrophic factor. Transgenic Res 1994 0.96
154 Differential effects of MK-801 on brain-derived neurotrophic factor mRNA levels in different regions of the rat brain. Exp Neurol 1993 0.95
155 Inhiition of neuronally induced tyrosine hydroxylase by nitinic receptor blockade. Eur J Pharmacol 1970 0.95
156 A second messenger required for nerve growth factor biological activity? Nature 1981 0.95
157 Nerve growth factor supply for sensory neurons: site of origin and competition with the sympathetic nervous system. Neurosci Lett 1985 0.95
158 Transforming growth factor-beta 1 stimulates expression of nerve growth factor in the rat CNS. Neuroreport 1990 0.95
159 Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation. J Cell Biol 1993 0.95
160 The significance of retrograde axonal transport for the accumulation of systemically administered nerve growth factor (NGF) in the rat superior cervical ganglion. Brain Res 1976 0.95
161 Different factors from the central nervous system and periphery regulate the survival of sensory neurones. Nature 1986 0.94
162 Effect of glucocorticoids on nerve growth factor-mediated enzyme induction in organ cultures of rat sympathetic ganglia: enchanced response and reduced time requirement to initiate enzyme induction. J Neurochem 1977 0.94
163 Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons. Neuron 1993 0.93
164 Retrograde axonal transport of 125I-tetanus toxin as a tool for tracing fiber connections in the central nervous system; connections of the rostral part of the rat neostriatum. Brain Res 1977 0.93
165 Significance of 'empty vesicles' in postganglionic sympathetic nerve terminals. Experientia 1967 0.93
166 Electron microscopic evidence for a transsynaptic migration of tetanus toxin in spinal cord motoneurons: an autoradiographic and morphometric study. Brain Res 1976 0.92
167 Laminin increases both levels and activity of tyrosine hydroxylase in calf adrenal chromaffin cells. J Cell Biol 1986 0.92
168 The synthesis of nerve growth factor (NGF) in developing skin is independent of innervation. Dev Biol 1988 0.92
169 Cell contact-mediated regulation of tyrosine hydroxylase synthesis in cultured bovine adrenal chromaffin cells. J Cell Biol 1983 0.92
170 Modulation of NGF-induced survival of chick sympathetic neurons by contact with a conditioned medium factor bound to the culture substrate. Brain Res 1982 0.92
171 Nerve growth factor-mediated induction of tyrosine hydroxylase and of neurite outgrowth in cultures of bovine adrenal chromaffin cells: dependence on developmental stage. Dev Biol 1982 0.92
172 The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments. J Physiol Paris 1996 0.92
173 Nerve growth factor and preganglionic cholinergic nerves; their relative importance to the development of the terminal adrenergic neuron. Brain Res 1972 0.91
174 Both nerve growth factor and high K+ concentrations support the survival of chick embryo sympathetic neurons. Evidence for a common mechanism of action. Exp Cell Res 1983 0.91
175 Brain derived neurotrophic factor. Prog Brain Res 1987 0.91
176 Phase difference in the induction of tyrosine hydroxylase in cell body and nerve terminals of sympathetic neurones. Proc Natl Acad Sci U S A 1970 0.90
177 Quantitation and purification of neurotrophic molecules. Cold Spring Harb Symp Quant Biol 1983 0.90
178 Fibroblast growth factor-5 promotes differentiation of cultured rat septal cholinergic and raphe serotonergic neurons: comparison with the effects of neurotrophins. Eur J Neurosci 1994 0.90
179 Communication between target organs and nerve cells: retrograde axonal transport and site of action of nerve growth factors. Cold Spring Harb Symp Quant Biol 1982 0.90
180 Proceedings: Failure to induce experimental hypertension in rats after intraventricular injection of 6-hydroxydopamine. Br J Pharmacol 1972 0.90
181 Increased formation of preganglionic synapses and axons due to a retrograde trans-synaptic action of nerve growth factor in the rat sympathetic nervous system. J Neurosci 1983 0.90
182 Rapid recovery of vascular adrenergic nerves in the rat after chemical sympathectomy with 6-hydroxydopamine. Br J Pharmacol 1973 0.89
183 Nerve growth factor: biological significance, measurement, and distribution. J Neurochem 1980 0.89
184 Induction of fibre outgrowth and choline acetyltransferase in PC12 pheochromocytoma cells by conditioned media from glial cells and organ extracts. Exp Cell Res 1979 0.88
185 The distribution of nerve growth factor in the male sex organs of mammals. J Neurochem 1980 0.88
186 Regulation of tyrosine hydroxylase and choline acetyltransferase activities by cell density in the PC12 rat pheochromocytoma clonal cell line. Exp Cell Res 1979 0.88
187 Increased activity of the peripheral sympathetic nervous system: induction of choline acetyltransferase in the preganglionic cholinergic neurone. Nature 1973 0.88
188 Neurotrophic factors and neuronal death. Ciba Found Symp 1987 0.88
189 Progenitor cells from embryonic chick dorsal root ganglia differentiate in vitro to neurons: biochemical and electrophysiological evidence. EMBO J 1985 0.87
190 Biological and immunological properties of the nerve growth factor from bovine seminal plasma: comparison with the properties of mouse nerve growth factor. Neuroscience 1983 0.87
191 Hypothermia induced by intraventricular administration of 6-hydroxydopamine in rats. Eur J Pharmacol 1971 0.87
192 Production of specific antibodies to choline acetyltransferase purified from pig brain. Neuroscience 1981 0.86
193 Location of an isoproterenol-responsive cyclic AMP pool in adrenergic nerve cell bodies and its relationship to tyrosine 3-monooxygenase induction. Proc Natl Acad Sci U S A 1974 0.86
194 The effect of stimulation of sympathetic nerves in the cat treated with reserpine, alpha-methyldopa and alpha-methylmetatyrosine. Br J Pharmacol Chemother 1966 0.86
195 Selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase in sympathetic ganglia in organ culture: role of glucocorticoids as modulators. Mol Pharmacol 1976 0.86
196 Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus. Int J Dev Neurosci 1994 0.86
197 Model experiments on the molecular mechanism of action of 6-hydroxydopamine. Mol Pharmacol 1971 0.86
198 Proceedings: The recovery of vascular adrenergic nerve function in the rat after chemical sympathectomy with 6-hydroxydopamine. Br J Pharmacol 1972 0.86
199 Transganglionic regulation of central terminals of dorsal root ganglion cells by nerve growth factor (NGF). Brain Res 1985 0.86
200 Diminished effects of sympathetic nerve stimulation in cats pretreated with disulfiram; liberation of dopamine as sympathetic transmitter. Life Sci 1965 0.86
201 Substrate requirement and media supplements necessary for the long-term survival of chick sympathetic and sensory neurons cultured without serum. Exp Cell Res 1982 0.86
202 Modulatory role of glucocorticoids on NGF-mediated enzyme induction in organ cultures of sympathetic ganglia. Brain Res 1976 0.86
203 Accumulation of 5-hydroxydopamine in 5-HT storage organelles of cat platelets and concomitant changes in platelet aggregation. Experientia 1969 0.86
204 Immunoelectron microscopic localization of laminin in normal and regenerating mouse sciatic nerve. J Neurocytol 1990 0.86
205 Nerve growth factor-mediated induction of tyrosine hydroxylase in rat superior cervical ganglia in vitro. J Biol Chem 1978 0.86
206 Developmental changes of nerve growth factor and its mRNA in the rat hippocampus: comparison with choline acetyltransferase. Dev Biol 1987 0.85
207 Dissociation between effects of nerve growth factor on tyrosine hydrolase and tubulin synthesis in sympathetic ganglia. Nature 1974 0.85
208 Neurally mediated control of enzymes involved in the synthesis of norepinephrine; are they regulated as an operational unit? Naunyn Schmiedebergs Arch Pharmakol 1971 0.85
209 Comparison between the effect of neuronal activity and nerve growth factor on the enzymes involved in the synthesis of norepinephrine. Pharmacol Rev 1972 0.84
210 Internalization of nerve growth factor by pheochromocytoma PC12 cells: absence of transfer to the nucleus. J Neurosci 1982 0.84
211 Actions of CNTF and neurotrophins on degenerating motoneurons: preclinical studies and clinical implications. J Neurol Sci 1994 0.84
212 Vulnerability of midbrain dopaminergic neurons in calbindin-D28k-deficient mice: lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice. Eur J Neurosci 1997 0.84
213 Relationship between the rate of axoplasmic transport and subcellular distribution of enzymes involved in the synthesis of norepinephrine. J Neurochem 1973 0.84
214 Effects of colchicine and cytochalasin B on the release of 3 H-norepinephrine from guinea-pig atria evoked by high potassium, nicotine and tyramine. Naunyn Schmiedebergs Arch Pharmacol 1973 0.83
215 Nerve growth factor as a mediator of information between effector organs and innervating neurons. Symp Soc Dev Biol 1978 0.83
216 [Antidromic activity induced by acetylcholine in the cardiac sympathetic nerve, and noradrenaline liberation under the influence of guanethidine]. Helv Physiol Pharmacol Acta 1968 0.83
217 Distinction between nerve growth factor anf glial factor. Nature 1975 0.83
218 Neuronally dependent induction of adrenal phenylethanolamine-N-methyltransferase by 6-hydroxydopamine. Biochem Pharmacol 1970 0.83
219 Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments. Brain Res 1990 0.83
220 Antibodies against mouse nerve growth factor interfere in vivo with the development of avian sensory and sympathetic neurones. Development 1988 0.83
221 The effect of alpha-methyl-tyrosine on peripheral sympathetic transmission. Life Sci 1966 0.83
222 Cholinergic denervation of the rat hippocampus by fimbrial transection leads to a transient accumulation of nerve growth factor (NGF) without change in mRNANGF content. Neurosci Lett 1986 0.83
223 Effect of pituitary and ACTH on the maintenance of basal tyrosine hydroxylase activity in the rat adrenal gland. Endocrinology 1970 0.83
224 Predicted amino acid sequence of bovine tyrosine hydroxylase and its similarity to tyrosine hydroxylases from other species. J Neurochem 1988 0.82
225 Rat ciliary neurotrophic factor (CNTF): gene structure and regulation of mRNA levels in glial cell cultures. Glia 1993 0.82
226 Early effects of nerve growth factor on adrenergic neurons: an electron microscopic morphometric study of the rat superior cervical ganglion. Cell Tissue Res 1975 0.82
227 Topography of choline acetyltransferase-containing neurons in the forebrain of the rat. Neurosci Lett 1982 0.82
228 Selective induction of tyrosine hydroxylase by cell-cell contact in bovine adrenal chromaffin cells is mimicked by plasma membranes. J Cell Biol 1986 0.82
229 Changes in enzyme patterns produced by high potassium concentration and dibutyryl cyclic AMP in organ cultures of sympathetic ganglia. J Neurochem 1974 0.82
230 bcl-2 messenger RNA is localized in neurons of the developing and adult rat brain. Neuroscience 1994 0.82
231 Selective uptake and retrograde axonal transport of dopamine-beta-hydroxylase antibodies in peripheral adrenergic neurons. Brain Res 1976 0.81
232 Circadian rhythm of tyrosine hydroxylase induction by short-term cold stress: modulatory action of glucocorticoids in newborn and adult rats. Proc Natl Acad Sci U S A 1975 0.81
233 Retrograde transport of tetanus toxin through a chain of two neurons. Brain Res 1979 0.81
234 Ultrastructural identification of storage compartments and localization of activity-dependent secretion of neurotrophin 6 in hippocampal neurons. Mol Cell Neurosci 2000 0.81
235 Interchangeability of nerve growth factor and high potassium in the long-term survival of chick sympathetic neurons in serum-free culture medium. Neurosci Lett 1984 0.81
236 Epoxide hydrase in human liver biopsy specimens: assay and properties. Biochem Pharmacol 1974 0.81
237 Mechanisms of tyrosine hydroxylase and dopamine beta-hydroxylase induction in organ cultures of rat sympathetic ganglia by potassium depolarization and cholinomimetics. Naunyn Schmiedebergs Arch Pharmacol 1976 0.81
238 Fine structural localization of exogenous 5-HT in vesicles of adrenergic nerve terminals. Experientia 1968 0.81
239 Immunosympathectomy: lack of evidence for a complement-mediated cytotoxic mechanism. Brain Res 1980 0.81
240 Effect of chemical sympathectomy on the content of acetylcholine, choline and choline acetyltransferase activity in the cat spleen and iris. J Physiol 1972 0.81
241 Presence of nerve growth factor receptors and catecholamine uptake in subpopulations of chick sympathetic neurons: correlation with survival factor requirements in culture. Dev Biol 1983 0.81
242 Retrograde axonal transport of nerve growth factor in the ciliary ganglion of the chick and the rat. Brain Res 1978 0.81
243 Quantitative aspects of the replacement of norepinephrine by dopamine as a sympathetic transmitter after inhibition of dopamine-beta-hydroxylase by disulfiram. J Pharmacol Exp Ther 1967 0.81
244 Organ culture of the rat adrenal medulla: a model system for the study of trans-synaptic enzyme induction. J Neurochem 1975 0.81
245 Experimental hypertension of the rat: reciprocal changes of norepinephrine turnover in heart and brain-stem. Jpn J Pharmacol 1970 0.81
246 Brain-derived neurotrophic factor increases neurotrophin-3 expression in cerebellar granule neurons. J Biol Chem 1994 0.80
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