17 beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androstan-1-en-3-one is an active site-directed slow time-dependent inhibitor of human steroid 5 alpha-reductase 1.

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Published in Biochemistry on March 01, 1994

Authors

G Tian1, J D Stuart, M L Moss, P L Domanico, H N Bramson, I R Patel, S H Kadwell, L K Overton, T A Kost, R A Mook

Author Affiliations

1: Department of Molecular Biochemistry, Glaxo Research Institute, Research Triangle Park, North Carolina 27709.

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