Published in J Biol Chem on January 21, 1994
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol (1999) 3.47
Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme. Proc Natl Acad Sci U S A (1996) 1.92
Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones. J Clin Invest (1994) 1.83
Physiology and pathophysiology of matrix metalloproteases. Amino Acids (2010) 1.83
Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers. Am J Pathol (1996) 1.72
A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest. Proc Natl Acad Sci U S A (2000) 1.61
The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse. Mol Biol Cell (1995) 1.60
The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. Mol Cell Biol (2001) 1.48
The Menstrual Cycle, Sex Hormones, and Anterior Cruciate Ligament Injury. J Athl Train (2002) 1.29
CIZ, a zinc finger protein that interacts with p130(cas) and activates the expression of matrix metalloproteinases. Mol Cell Biol (2000) 1.16
Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas. Am J Pathol (2002) 1.14
Cloning, sequencing and characterization of the 5'-flanking region of the human collagenase-3 gene. Biochem J (1997) 1.12
Matrix metalloproteinase-7 expression in gastric carcinoma. Gut (1996) 1.11
Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones. Endocr Relat Cancer (2000) 1.06
Transforming growth factor-beta and matrix metalloproteinases: functional interactions in tumor stroma-infiltrating myeloid cells. ScientificWorldJournal (2014) 1.03
Expression of c-ets-1 mRNA is associated with an invasive, EMT-derived phenotype in breast carcinoma cell lines. Clin Exp Metastasis (1997) 1.03
Helicobacter pylori upregulates matrilysin (MMP-7) in epithelial cells in vivo and in vitro in a Cag dependent manner. Gut (2003) 0.97
In vivo matrix metalloproteinase-7 substrates identified in the left ventricle post-myocardial infarction using proteomics. J Proteome Res (2010) 0.95
Dimerumic acid inhibits SW620 cell invasion by attenuating H₂O₂-mediated MMP-7 expression via JNK/C-Jun and ERK/C-Fos activation in an AP-1-dependent manner. Int J Biol Sci (2011) 0.93
Loss of JunB activity enhances stromelysin 1 expression in a model of the epithelial-to-mesenchymal transition of mouse skin tumors. Mol Cell Biol (2001) 0.92
Identification of a cytokine-induced repressor of interleukin-1 stimulated expression of stromelysin 1 (MMP-3). J Biol Chem (1999) 0.87
Interleukin-1beta-induced promatrilysin expression is mediated by NFkappaB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP. Neoplasia (2002) 0.85
A glimpse of matrix metalloproteinases in diabetic nephropathy. Curr Med Chem (2014) 0.84
Unique organization and involvement of GAGA factors in transcriptional regulation of the Xenopus stromelysin-3 gene. Nucleic Acids Res (1998) 0.84
Interleukin-1 beta influences on lysyl oxidases and matrix metalloproteinases profile of injured anterior cruciate ligament and medial collateral ligament fibroblasts. Int Orthop (2012) 0.83
Antisense E1AF transfection restrains oral cancer invasion by reducing matrix metalloproteinase activities. Am J Pathol (1997) 0.83
Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma. Br J Cancer (2002) 0.83
Modulation of neutral protease expression in human mesangial cells by hyperglycaemic culture. Biochem J (1996) 0.82
Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney. Physiol Rep (2013) 0.80
Differential modulation of proliferation, matrix metalloproteinase expression and invasion of human head and neck squamous carcinoma cells by c-erbB ligands. Clin Exp Metastasis (1999) 0.80
Matrix metalloproteinase and cytokine profiles in monocytes over the course of stroke. J Clin Immunol (2001) 0.78
Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression. Oncogenesis (2015) 0.78
MMP-7 knock-in corneal fibroblast cell lines secrete MMP-7 with proteolytic activity towards collagen XVIII. Curr Eye Res (2010) 0.77
Autocrine motility factor stimulates the invasiveness of malignant cells as well as up-regulation of matrix metalloproteinase-3 expression via a MAPK pathway. FEBS Lett (2008) 0.77
Matrix Metalloproteinases-7 and Kidney Fibrosis. Front Physiol (2017) 0.75
Raf/ERK/Nrf2 signaling pathway and MMP-7 expression involvement in the trigonelline-mediated inhibition of hepatocarcinoma cell migration. Food Nutr Res (2015) 0.75
Down-regulation of matrix metalloproteinase-7 inhibits metastasis of human anaplastic thyroid cancer cell line. Clin Exp Metastasis (2011) 0.75
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science (1999) 6.49
Changing views of the role of matrix metalloproteinases in metastasis. J Natl Cancer Inst (1997) 5.07
Matrix metalloproteinases: they're not just for matrix anymore! Curr Opin Cell Biol (2001) 4.99
Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol (2000) 4.98
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc Natl Acad Sci U S A (1997) 3.96
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors. Oncogene (1999) 3.95
Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts. EMBO J (1985) 3.60
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J Cell Sci (2001) 3.51
Evidence for a prostate cancer susceptibility locus on the X chromosome. Nat Genet (1998) 2.90
Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts. Mol Cell Biol (1986) 2.74
Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Am J Pathol (1996) 2.50
Matrix metalloproteinases: multifunctional contributors to tumor progression. Mol Med Today (2000) 2.44
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci U S A (1994) 2.43
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis. Curr Biol (2000) 2.42
Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption. J Clin Invest (2000) 2.39
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc Natl Acad Sci U S A (1986) 2.28
Structure-function relationships in the collagenase family member transin. J Biol Chem (1988) 2.15
Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem (2001) 2.12
Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions. Int J Biochem Cell Biol (1996) 2.12
TGF-beta 1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence. Cell (1990) 2.09
Epidermal growth factor or serum stimulation of rat fibroblasts induces an elevation in mRNA levels for lactate dehydrogenase and other glycolytic enzymes. Nucleic Acids Res (1985) 2.08
Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways. Science (1988) 2.05
Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development. Mol Biol Cell (1995) 1.96
Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinog (1991) 1.95
Stimulation of rat mesangial cell proliferation by macrophage interleukin 1. J Immunol (1983) 1.94
Matrilysin expression and function in airway epithelium. J Clin Invest (1998) 1.94
Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis. Cancer Metastasis Rev (1995) 1.93
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis. Mol Carcinog (1994) 1.92
Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones. J Clin Invest (1994) 1.83
Neutral proteinase activity produced in vitro by cells of the glomerular mesangium. Kidney Int (1983) 1.81
Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo. Cancer Res (1994) 1.80
Epidermal growth factor. Ability of tumor promoter to alter its degradation, receptor affinity and receptor number. J Biol Chem (1980) 1.65
Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J Biol Chem (1990) 1.63
The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis. Cancer Res (1998) 1.60
The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse. Mol Biol Cell (1995) 1.60
A thymocyte-activating factor derived from glomerular mesangial cells. J Immunol (1983) 1.59
Coordinate expression of matrix metalloproteinase family members in the uterus of normal, matrilysin-deficient, and stromelysin-1-deficient mice. Endocrinology (1997) 1.50
Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption. J Clin Invest (2000) 1.49
The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. Mol Cell Biol (2001) 1.48
Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cells. Enzyme Protein (1996) 1.45
Further purification of epidermal growth factor by high-performance liquid chromatography. Anal Biochem (1982) 1.42
Increasing film-focus distance (FFD) reduces radiation dose for x-ray examinations. Radiat Prot Dosimetry (2004) 1.42
Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epithelium. Mol Biol Cell (2001) 1.40
Matrix metalloproteinases as mediators of reproductive function. Mol Hum Reprod (1997) 1.40
Glomerular mesangial cell-specific transactivation of matrix metalloproteinase 2 transcription is mediated by YB-1. J Biol Chem (1997) 1.39
Cell culture approaches to the analysis of glomerular inflammation. Kidney Int (1986) 1.37
The matrix metalloprotease matrilysin (PUMP) is expressed in developing human mononuclear phagocytes. J Biol Chem (1992) 1.34
Interleukin 1 and the glomerular mesangium. I. Purification and characterization of a mesangial cell-derived autogrowth factor. J Immunol (1986) 1.34
The 31-kDa precursor of interleukin 1 alpha is myristoylated on specific lysines within the 16-kDa N-terminal propiece. Proc Natl Acad Sci U S A (1993) 1.33
Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis. Neoplasia (2002) 1.33
Activation of glomerular mesangial cells by the terminal membrane attack complex of complement. J Immunol (1987) 1.30
A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes. Mol Carcinog (1997) 1.27
Myristyl acylation of the tumor necrosis factor alpha precursor on specific lysine residues. J Exp Med (1992) 1.26
Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle. Am J Obstet Gynecol (1993) 1.26
Acylation of monocyte and glomerular mesangial cell proteins. Myristyl acylation of the interleukin 1 precursors. J Clin Invest (1988) 1.25
Matrix metalloproteinase 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation. J Biol Chem (1996) 1.25
A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription. J Biol Chem (1998) 1.25
TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1. Mol Cell Biol (2000) 1.24
Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms. Mol Carcinog (1999) 1.23
Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression. Invasion Metastasis (1995) 1.23
EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. Int J Dev Biol (1991) 1.22
Epidermal growth factor stimulation of stromelysin mRNA in rat fibroblasts requires induction of proto-oncogenes c-fos and c-jun and activation of protein kinase C. Mol Cell Biol (1990) 1.22
Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo. Cancer Res (1998) 1.22
Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney. J Clin Invest (1995) 1.21
The N-terminal propiece of interleukin 1 alpha is a transforming nuclear oncoprotein. Proc Natl Acad Sci U S A (1997) 1.18
Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis. Cancer Res (1995) 1.18
Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice. J Clin Invest (1997) 1.18
Tumor progression: defining the soil round the tumor seed. Curr Biol (2001) 1.17
Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene. Nucleic Acids Res (1987) 1.17
Mesangial cell hillocks. Nodular foci of exaggerated growth of cells and matrix in prolonged culture. Am J Pathol (1986) 1.16
Thrombospondin secretion by cultured human glomerular mesangial cells. Am J Pathol (1987) 1.14
Transforming growth factor beta mediates the progesterone suppression of an epithelial metalloproteinase by adjacent stroma in the human endometrium. Proc Natl Acad Sci U S A (1995) 1.13
Mutational analysis of the transin (rat stromelysin) autoinhibitor region demonstrates a role for residues surrounding the "cysteine switch". J Biol Chem (1991) 1.12
Transforming growth factor-beta 1 stimulates glomerular mesangial cell synthesis of the 72-kd type IV collagenase. Am J Pathol (1994) 1.11
Interleukin 1: the patterns of translation and intracellular distribution support alternative secretory mechanisms. J Cell Physiol (1992) 1.10
Cytosolic calcium regulates epidermal growth factor endocytosis in rat pancreas and cultured fibroblasts. Proc Natl Acad Sci U S A (1984) 1.10
Molecular basis of invasion in breast cancer. Cell Mol Life Sci (2007) 1.10
The role of the matrix metalloproteinase stromelysin in the progression of squamous cell carcinomas. Am J Med Sci (1991) 1.09
The purification and characterization of a glomerular-basement-membrane-degrading neutral proteinase from rat mesangial cells. Biochem J (1988) 1.09
Proteinases and glomerular matrix turnover. Kidney Int (1992) 1.08
Stromelysin in tumor progression and metastasis. Cancer Metastasis Rev (1990) 1.07
Reduced penetrance alleles for Huntington's disease: a multi-centre direct observational study. J Med Genet (2007) 1.07
Characterization of a glomerular epithelial cell metalloproteinase as matrix metalloproteinase-9 with enhanced expression in a model of membranous nephropathy. J Clin Invest (1996) 1.06
Expression of matrix metalloproteinase genes in transformed rat cell lines of high and low metastatic potential. Cancer Res (1992) 1.05
Human mesangial cells secrete a GBM-degrading neutral proteinase and a specific inhibitor. Kidney Int (1989) 1.05
Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis. Int J Cancer (1998) 1.05
Enhancement of glomerular mesangial cell neutral proteinase secretion by macrophages: role of interleukin 1. J Immunol (1986) 1.04
The mesangium and glomerulonephritis. Klin Wochenschr (1982) 1.04
Stromal-epithelial interaction mediates steroidal regulation of metalloproteinase expression in human endometrium. Proc Natl Acad Sci U S A (1994) 1.03
Transforming growth factor beta 1 and cAMP inhibit transcription of epidermal growth factor- and oncogene-induced transin RNA. J Biol Chem (1988) 1.01
A switch from stromal to tumor cell expression of stromelysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression. Mol Carcinog (1994) 1.01
Complex roles of matrix metalloproteinases in tumor progression. Curr Top Microbiol Immunol (1996) 1.00
Matrix metalloproteinases in remodeling of the normal and neoplastic mammary gland. J Mammary Gland Biol Neoplasia (1998) 1.00
Overexpression of the matrix metalloproteinase matrilysin results in premature mammary gland differentiation and male infertility. Mol Biol Cell (1998) 0.99
Insights from knock-out models concerning postischemic release of TNFalpha from isolated mouse hearts. J Mol Cell Cardiol (2006) 0.98
Molecular characterization of a low-molecular-mass matrix metalloproteinase secreted by glomerular mesangial cells as PUMP-1. Biochem J (1992) 0.97