Published in J Biol Chem on August 25, 1988
Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science (1995) 6.35
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Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J Cell Biol (1997) 4.22
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Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen. Proc Natl Acad Sci U S A (1990) 2.00
Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development. Mol Biol Cell (1995) 1.96
Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen. Proc Natl Acad Sci U S A (1992) 1.79
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Fragmentation of human polymorphonuclear-leucocyte collagenase. Biochem J (1993) 1.32
Purification of recombinant human prostromelysin. Studies on heat activation to give high-Mr and low-Mr active forms, and a comparison of recombinant with natural stromelysin activities. Biochem J (1991) 1.24
Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. Mol Biol Cell (2004) 1.18
Structure-function relationship of human neutrophil collagenase: identification of regions responsible for substrate specificity and general proteinase activity. Proc Natl Acad Sci U S A (1993) 1.14
Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo. EMBO J (1990) 1.13
Matrix metalloproteases and lung disease. Thorax (1994) 1.13
Autocatalytic polysialylation of polysialyltransferase-1. EMBO J (1996) 1.01
ST3GAL3 mutations impair the development of higher cognitive functions. Am J Hum Genet (2011) 1.01
Overexpression of the matrix metalloproteinase matrilysin results in premature mammary gland differentiation and male infertility. Mol Biol Cell (1998) 0.99
Structural and functional characterization of tissue factor pathway inhibitor following degradation by matrix metalloproteinase-8. Biochem J (2002) 0.95
Evidence for a cooperative role of gelatinase A and membrane type-1 matrix metalloproteinase during Xenopus laevis development. Mech Dev (2006) 0.94
Cloning and characterization of cDNAs for matrix metalloproteinases of regenerating newt limbs. Proc Natl Acad Sci U S A (1996) 0.91
Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferase. Proc Natl Acad Sci U S A (1998) 0.91
A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate. Proc Natl Acad Sci U S A (1993) 0.89
Expression cloning of a CMP-NeuAc:NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1'Cer alpha 2,8-sialyltransferase (GD3 synthase) from human melanoma cells. Proc Natl Acad Sci U S A (1994) 0.84
Modulation of neutral protease expression in human mesangial cells by hyperglycaemic culture. Biochem J (1996) 0.82
Expression of catalytically active matrix metalloproteinase-1 in dermal fibroblasts induces collagen fragmentation and functional alterations that resemble aged human skin. Aging Cell (2013) 0.82
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N-glycosylation is required for full enzymic activity of the murine galactosylceramide sulphotransferase. Biochem J (2002) 0.78
A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research. Glycoconj J (1999) 0.77
The evolution of galactose alpha2,3-sialyltransferase: Ciona intestinalis ST3GAL I/II and Takifugu rubripes ST3GAL II sialylate Galbeta1,3GalNAc structures on glycoproteins but not glycolipids. Glycoconj J (2007) 0.76
Murine matrix metalloproteinase-20 overexpression stimulates cell invasion into the enamel layer via enhanced Wnt signaling. Sci Rep (2016) 0.75
Organization and expression of eucaryotic split genes coding for proteins. Annu Rev Biochem (1981) 49.46
The ovalbumin gene-sequence of putative control regions. Nucleic Acids Res (1980) 18.04
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Organisation and sequences at the 5' end of a cloned complete ovalbumin gene. Nature (1979) 9.30
Ovalbumin gene is split in chicken DNA. Nature (1977) 7.05
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science (1999) 6.49
Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase. Proc Natl Acad Sci U S A (1981) 5.38
Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res (1982) 5.14
Changing views of the role of matrix metalloproteinases in metastasis. J Natl Cancer Inst (1997) 5.07
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Plasmids for the cloning and expression of full-length double-stranded cDNAs under control of the SV40 early or late gene promoter. Nucleic Acids Res (1983) 4.33
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc Natl Acad Sci U S A (1997) 3.96
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors. Oncogene (1999) 3.95
Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts. EMBO J (1985) 3.60
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J Cell Sci (2001) 3.51
Isolation by molecular cloning of a fragment in the split ovalbumin gene. Nature (1978) 3.40
hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer. Mol Cell Biol (1999) 2.93
The RNA-binding protein TIA-1 is a novel mammalian splicing regulator acting through intron sequences adjacent to a 5' splice site. Mol Cell Biol (2000) 2.75
Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts. Mol Cell Biol (1986) 2.74
Organization of coding and intervening sequences in the chicken ovalbumin split gene. Cell (1978) 2.61
Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7. Nucleic Acids Res (1984) 2.52
Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Am J Pathol (1996) 2.50
The collagenase gene family in humans consists of at least four members. Biochem J (1988) 2.45
Matrix metalloproteinases: multifunctional contributors to tumor progression. Mol Med Today (2000) 2.44
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci U S A (1994) 2.43
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis. Curr Biol (2000) 2.42
Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption. J Clin Invest (2000) 2.39
Exon and intron sequences, respectively, repress and activate splicing of a fibroblast growth factor receptor 2 alternative exon. Mol Cell Biol (1995) 2.34
The c-Ets oncoprotein activates the stromelysin promoter through the same elements as several non-nuclear oncoproteins. EMBO J (1991) 2.30
Psychological and social evaluation in cases of deliberate self-poisoning seen in an accident department. Br Med J (Clin Res Ed) (1982) 2.29
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc Natl Acad Sci U S A (1986) 2.28
A new immunohistochemical antibody for the assessment of estrogen receptor status on routine formalin-fixed tissue samples. Hum Pathol (1995) 2.20
Corrected splicing of a chicken ovalbumin gene transcript in mouse L cells. Proc Natl Acad Sci U S A (1980) 2.19
Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem (2001) 2.12
Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts. Nature (1988) 2.12
Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions. Int J Biochem Cell Biol (1996) 2.12
TGF-beta 1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence. Cell (1990) 2.09
In vitro mutational analysis of cis-acting RNA translational elements within the poliovirus type 2 5' untranslated region. J Virol (1991) 2.08
Epidermal growth factor or serum stimulation of rat fibroblasts induces an elevation in mRNA levels for lactate dehydrogenase and other glycolytic enzymes. Nucleic Acids Res (1985) 2.08
A novel putative receptor protein tyrosine kinase of the met family. Oncogene (1993) 2.06
Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways. Science (1988) 2.05
TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAs. J Biol Chem (2001) 1.96
Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development. Mol Biol Cell (1995) 1.96
Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinog (1991) 1.95
Matrilysin expression and function in airway epithelium. J Clin Invest (1998) 1.94
Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis. Cancer Metastasis Rev (1995) 1.93
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis. Mol Carcinog (1994) 1.92
Identification of the ron gene product as the receptor for the human macrophage stimulating protein. Science (1994) 1.84
Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones. J Clin Invest (1994) 1.83
Multiple interdependent sequence elements control splicing of a fibroblast growth factor receptor 2 alternative exon. Mol Cell Biol (1997) 1.83
T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis. J Exp Med (1996) 1.80
Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo. Cancer Res (1994) 1.80
One size fits all: a surgical technique for the correction of all types of prominent ears. Plast Reconstr Surg (1999) 1.71
Synthetic donor and acceptor splice sites function in an RNA polymerase B (II) transcription unit. EMBO J (1984) 1.66
Epidermal growth factor. Ability of tumor promoter to alter its degradation, receptor affinity and receptor number. J Biol Chem (1980) 1.65
Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J Biol Chem (1990) 1.63
No more than seven interruptions in the ovalbumin gene: comparison of genomic and double-stranded cDNA sequences. Nucleic Acids Res (1979) 1.60
The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis. Cancer Res (1998) 1.60
Assessment of the new proliferation marker MIB1 in breast carcinoma using image analysis: associations with other prognostic factors and survival. Br J Cancer (1995) 1.60
The exon sequence TAGG can inhibit splicing. Nucleic Acids Res (1996) 1.60
The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse. Mol Biol Cell (1995) 1.60
Structure and expression of the human gene for the matrix metalloproteinase matrilysin. J Biol Chem (1994) 1.55
Coordinate expression of matrix metalloproteinase family members in the uterus of normal, matrilysin-deficient, and stromelysin-1-deficient mice. Endocrinology (1997) 1.50
Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption. J Clin Invest (2000) 1.49
The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors. Mol Cell Biol (2001) 1.48
Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cells. Enzyme Protein (1996) 1.45
Further purification of epidermal growth factor by high-performance liquid chromatography. Anal Biochem (1982) 1.42
Control of BEK and K-SAM splice sites in alternative splicing of the fibroblast growth factor receptor 2 pre-mRNA. Mol Cell Biol (1993) 1.41
Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epithelium. Mol Biol Cell (2001) 1.40
The greater the ignorance, the greater the dogmatism. Hastings Cent Rep (1998) 1.40
Matrix metalloproteinases as mediators of reproductive function. Mol Hum Reprod (1997) 1.40
Multiple mRNAs code for proteins related to the BEK fibroblast growth factor receptor. Oncogene (1991) 1.40
c-erbB-2 oncoprotein expression in primary and advanced breast cancer. Br J Cancer (1991) 1.37
Pump-1 cDNA codes for a protein with characteristics similar to those of classical collagenase family members. Biochemistry (1989) 1.35
The matrix metalloprotease matrilysin (PUMP) is expressed in developing human mononuclear phagocytes. J Biol Chem (1992) 1.34
Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis. Neoplasia (2002) 1.33
A role for branchpoints in splicing in vivo. Nature (1985) 1.32
Expression of metalloproteinase genes in human prostate cancer. J Cancer Res Clin Oncol (1991) 1.31
cis-acting translational effects of the 5' noncoding region of c-myc mRNA. Mol Cell Biol (1988) 1.30
Related fibroblast growth factor receptor genes exist in the human genome. Proc Natl Acad Sci U S A (1990) 1.29
Expression of collagenase-related metalloproteinase genes in human lung or head and neck tumours. Int J Cancer (1991) 1.29
A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate-induced invasion in mouse keratinocytes. Mol Carcinog (1997) 1.27
Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle. Am J Obstet Gynecol (1993) 1.26
Expression of epidermal growth factor receptor in breast carcinoma. J Clin Pathol (1990) 1.25