Published in J Cell Biol on April 01, 1993
Force mapping in epithelial cell migration. Proc Natl Acad Sci U S A (2005) 5.08
Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J Cell Biol (1993) 3.32
Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe. Am J Pathol (2009) 3.09
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nat Med (2008) 3.00
Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly. Mol Biol Cell (1998) 2.71
The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J Cell Biol (1995) 2.67
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses. J Cell Biol (2000) 2.48
Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway. Mol Cell Biol (1997) 2.43
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J (2006) 2.38
Targeting the HGF/Met signalling pathway in cancer. Eur J Cancer (2010) 2.20
The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase. Mol Cell Biol (2000) 2.07
RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. EMBO J (1994) 2.04
Essential role of Gab1 for signaling by the c-Met receptor in vivo. J Cell Biol (2000) 1.97
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells. J Cell Biol (1995) 1.91
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland. J Cell Biol (1995) 1.91
Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing. J Cell Biol (1995) 1.85
Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J Cell Biol (1995) 1.79
The mutationally activated Met receptor mediates motility and metastasis. Proc Natl Acad Sci U S A (1998) 1.76
Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion. Mol Cell Biol (2006) 1.76
Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain. Mol Cell Biol (1995) 1.73
The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase. Mol Cell Biol (1999) 1.67
Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction. J Cell Biol (1994) 1.64
Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis. J Cell Biol (1998) 1.56
Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy. Proc Natl Acad Sci U S A (2003) 1.42
The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro. Mol Biol Cell (1996) 1.42
Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas. Br J Cancer (1996) 1.35
Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions. Mol Biol Cell (2002) 1.34
Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity. J Cell Biol (1994) 1.33
EphA kinase activation regulates HGF-induced epithelial branching morphogenesis. J Cell Biol (2003) 1.32
Met and the epidermal growth factor receptor act cooperatively to regulate final nephron number and maintain collecting duct morphology. Development (2009) 1.31
Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering. Mol Biol Cell (2000) 1.31
A natural hepatocyte growth factor/scatter factor autocrine loop in myoblast cells and the effect of the constitutive Met kinase activation on myogenic differentiation. J Cell Biol (1997) 1.30
Hepatocyte growth factor and macrophage inflammatory protein 1 beta: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells. Proc Natl Acad Sci U S A (1994) 1.25
Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. J Cell Biol (1994) 1.21
Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2. J Cell Biol (1996) 1.19
Regulation of uveal melanoma interconverted phenotype by hepatocyte growth factor/scatter factor (HGF/SF). Am J Pathol (1998) 1.17
Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts. Mol Biol Cell (2003) 1.16
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases. J Cell Biol (1996) 1.16
Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells. Breast Cancer Res (2010) 1.14
A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor. Proc Natl Acad Sci U S A (1996) 1.14
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells. Proc Natl Acad Sci U S A (1995) 1.13
Sequential activation of ERK and repression of JNK by scatter factor/hepatocyte growth factor in madin-darby canine kidney epithelial cells. Mol Biol Cell (2000) 1.12
Emerging roles for crk in human cancer. Genes Cancer (2010) 1.09
Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma. Br J Cancer (2011) 1.09
Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells. BMC Cancer (2006) 1.07
Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis. Mol Biol Cell (2002) 1.04
The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering. Mol Biol Cell (1999) 1.03
Detection of MET oncogene/hepatocyte growth factor receptor in lymph node metastases from head and neck squamous cell carcinomas. Eur Arch Otorhinolaryngol (1997) 0.97
Targeting the Met signaling pathway in renal cancer. Expert Rev Anticancer Ther (2009) 0.96
Crosstalk between the alpha2beta1 integrin and c-met/HGF-R regulates innate immunity. Blood (2008) 0.95
Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling. Mol Biol Cell (2007) 0.95
Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts. Cilia (2012) 0.94
Inhibition of neoplastic development in the liver by hepatocyte growth factor in a transgenic mouse model. Proc Natl Acad Sci U S A (1996) 0.94
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells. J Cell Biol (2004) 0.92
A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol (2013) 0.90
Prenatal expression of MET receptor tyrosine kinase in the fetal mouse dorsal raphe nuclei and the visceral motor/sensory brainstem. Dev Neurosci (2013) 0.87
The decreased metastatic potential of rhabdomyosarcoma cells obtained through MET receptor downregulation and the induction of differentiation. Cell Death Dis (2013) 0.86
Characterization of biliary epithelial cells isolated from needle biopsies of human liver in the presence of hepatocyte growth factor. Am J Pathol (1995) 0.86
Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion. Mol Biol Cell (2000) 0.85
Phase I ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma. Br J Cancer (2014) 0.85
Distinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5. BMC Genomics (2009) 0.84
Role of HGF/c-Met in serum-starved ARPE-19 cells. Korean J Ophthalmol (2007) 0.84
Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function. J Biol Chem (2011) 0.82
In vivo cancer biomarkers of esophageal neoplasia. Cancer Biomark (2008) 0.82
Differential expression of E-cadherin and beta catenin in primary and metastatic Wilms's tumours. Mol Pathol (2003) 0.82
The tyrosine kinase receptor c-met, its cognate ligand HGF and the tyrosine kinase receptor trasducers STAT3, PI3K and RHO in thyroid nodules associated with Hashimoto's thyroiditis: an immunohistochemical characterization. Eur J Histochem (2010) 0.81
Application perspectives of localization microscopy in virology. Histochem Cell Biol (2014) 0.81
Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema. BMC Pulm Med (2005) 0.81
C-met activation is necessary but not sufficient for liver colonization by B16 murine melanoma cells. Clin Exp Metastasis (1998) 0.80
Current understanding of the molecular mechanisms of kidney cancer: a primer for urologists. Can Urol Assoc J (2007) 0.78
Measuring collective cell movement and extracellular matrix interactions using magnetic resonance imaging. Sci Rep (2013) 0.78
Fetal growth restriction and hepatocyte growth factor. Arch Dis Child Fetal Neonatal Ed (1997) 0.77
Circulating interleukin-8 and plasminogen activator inhibitor-1 are increased in women with ovarian carcinoma. Results Immunol (2012) 0.77
Expression of hepatocyte growth factor and its receptor met in Wilms' tumors and nephrogenic rests reflects their roles in kidney development. Clin Cancer Res (2009) 0.76
MET receptor is a potential therapeutic target in high grade cervical cancer. Oncotarget (2015) 0.76
Late intervention with the small molecule BB3 mitigates postischemic kidney injury. Am J Physiol Renal Physiol (2016) 0.75
Hepatocyte Growth Factor/C-Met Axis in Thyroid Cancer: From Diagnostic Biomarker to Therapeutic Target. Biomark Insights (2017) 0.75
The beta-subunit of the hepatocyte growth factor/scatter factor (HGF/SF) receptor phosphorylates and associates with CrkII: expression of CrkII enhances HGF/SF-induced mitogenesis. Biochem J (2000) 0.75
Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts. Oncotarget (2016) 0.75
c-Met expression and activity in urogenital cancers - novel aspects of signal transduction and medical implications. Cell Commun Signal (2017) 0.75
Role of met axis in head and neck cancer. Cancers (Basel) (2013) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell (1991) 11.51
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell (1991) 8.99
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science (1991) 8.68
Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J (1988) 7.98
Molecular cloning and expression of human hepatocyte growth factor. Nature (1989) 6.91
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol (1989) 6.31
Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature (1987) 6.26
Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature (1984) 5.85
Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science (1991) 5.64
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol (1992) 5.04
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell (1991) 4.98
The trk proto-oncogene encodes a receptor for nerve growth factor. Cell (1991) 4.54
Identification of heregulin, a specific activator of p185erbB2. Science (1992) 4.17
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol (1990) 4.05
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci U S A (1987) 3.99
The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science (1991) 3.86
Expression and structure of the human NGF receptor. Cell (1986) 3.82
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene (1991) 3.41
Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J (1990) 3.27
Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci U S A (1991) 3.27
Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. Biochem Biophys Res Commun (1989) 3.21
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J (1991) 3.20
Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature (1992) 3.13
Molecular and biochemical characterization of the human trk proto-oncogene. Mol Cell Biol (1989) 3.10
Tyrosine kinase receptor indistinguishable from the c-met protein. Nature (1989) 3.00
Gene transfer and molecular cloning of the rat nerve growth factor receptor. Nature (1987) 2.98
A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. Proc Natl Acad Sci U S A (1991) 2.93
Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell (1991) 2.78
Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell (1992) 2.77
Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. Proc Natl Acad Sci U S A (1989) 2.61
Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocytes. Cancer Res (1989) 2.59
Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis. Nature (1992) 2.46
Epithelial morphogenesis. Cell (1992) 2.43
Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J Clin Invest (1988) 2.22
Purification and subunit structure of hepatocyte growth factor from rat platelets. FEBS Lett (1987) 2.13
The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. Cell (1991) 1.97
Biosynthesis of the protein encoded by the c-met proto-oncogene. Oncogene (1989) 1.92
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation. Mol Cell Biol (1991) 1.90
Developmentally regulated conversion of mesenchyme to epithelium. FASEB J (1989) 1.87
Hepatocytes and scatter factor. Nature (1990) 1.77
Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system. Development (1990) 1.75
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Proc Natl Acad Sci U S A (1992) 1.70
Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding. EMBO J (1992) 1.68
Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development. Genes Dev (1990) 1.67
Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene. Cell Growth Differ (1990) 1.62
C-terminal truncated forms of Met, the hepatocyte growth factor receptor. Mol Cell Biol (1991) 1.53
Isolation and expression of cDNA for different forms of hepatocyte growth factor from human leukocyte. Biochem Biophys Res Commun (1990) 1.49
Smooth muscle releases an epithelial cell scatter factor which binds to heparin. In Vitro Cell Dev Biol (1989) 1.48
Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells. Proc Natl Acad Sci U S A (1992) 1.48
Identification of the major autophosphorylation site of the Met/hepatocyte growth factor receptor tyrosine kinase. J Biol Chem (1991) 1.48
Identification of a competitive HGF antagonist encoded by an alternative transcript. Science (1991) 1.44
Identity of a tumor cytotoxic factor from human fibroblasts and hepatocyte growth factor. Biochem Biophys Res Commun (1990) 1.37
Characterization of the mouse met proto-oncogene. Oncogene (1988) 1.31
Epithelial scatter factor and development of the chick embryonic axis. Development (1990) 1.28
Purified scatter factor stimulates epithelial and vascular endothelial cell migration. Proc Soc Exp Biol Med (1990) 1.20
Comparison of biological and immunochemical properties indicates that scatter factor and hepatocyte growth factor are indistinguishable. J Cell Sci (1991) 1.20
Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors. EMBO J (1989) 1.17
Hepatocyte growth factor has potent anti-proliferative activity in various tumor cell lines. FEBS Lett (1991) 1.16
An alternatively processed mRNA generated from human hepatocyte growth factor gene. Eur J Biochem (1991) 1.15
Transient and locally restricted expression of the ros1 protooncogene during mouse development. EMBO J (1991) 1.14
Autonomous functions of structural domains on human tissue-type plasminogen activator. Proc Natl Acad Sci U S A (1986) 1.11
Scatter factor from human embryonic lung fibroblasts is probably identical to hepatocyte growth factor. Biochem Biophys Res Commun (1991) 1.01
Expression of a human hepatocyte growth factor/scatter factor cDNA in MDCK epithelial cells influences cell morphology, motility, and anchorage-independent growth. J Cell Biol (1992) 0.96
Expression of the met-receptor and its ligand, HGF-SF during mouse embryogenesis. EXS (1993) 0.94
Characterization of hepatocyte-growth-factor receptors on Meth A cells. Eur J Biochem (1992) 0.88
Replacement of the human insulin receptor transmembrane and cytoplasmic domains by corresponding domains of the oncogene product v-ros leads to accelerated internalization, degradation, and down-regulation. J Biol Chem (1990) 0.80
Functional interaction of beta-catenin with the transcription factor LEF-1. Nature (1996) 15.88
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol (1991) 8.60
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell (2001) 8.41
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science (1998) 8.27
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol (1989) 6.31
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol (1993) 5.86
Requirement for beta-catenin in anterior-posterior axis formation in mice. J Cell Biol (2000) 4.36
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J Cell Biol (1994) 4.34
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol (1990) 4.05
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol (1985) 3.77
Detection of human immunodeficiency virus type 1 provirus in mononuclear cells by in situ polymerase chain reaction. N Engl J Med (1992) 3.64
New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev (2001) 3.63
Double-blind, placebo-controlled food challenge (DBPCFC) as an office procedure: a manual. J Allergy Clin Immunol (1988) 3.57
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. Nature (1996) 3.00
Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol (1993) 2.84
In vivo distribution and turnover of fluorescently labeled actin microinjected into human fibroblasts. Proc Natl Acad Sci U S A (1979) 2.71
Microinjection of fluorescently labeled proteins into living cells with emphasis on cytoskeletal proteins. Int Rev Cytol (1982) 2.70
E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res (1991) 2.67
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. EMBO J (1992) 2.65
Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody. Cell (1983) 2.56
E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res (1993) 2.55
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. II. The role of ATP. J Cell Biol (1977) 2.54
Inhibitory action of transforming growth factor beta on endothelial cells. Proc Natl Acad Sci U S A (1987) 2.50
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses. J Cell Biol (2000) 2.48
Stress fiber sarcomeres of fibroblasts are contractile. Cell (1980) 2.45
E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci U S A (1994) 2.35
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart. J Cell Biol (1996) 2.27
Essential role of Gab1 for signaling by the c-Met receptor in vivo. J Cell Biol (2000) 1.97
V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift. J Cell Biol (1995) 1.92
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells. J Cell Biol (1995) 1.91
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland. J Cell Biol (1995) 1.91
Transforming growth factor-beta inhibits endothelial cell proliferation. Biochem Biophys Res Commun (1986) 1.86
Epithelial-mesenchymal transitions in cancer progression. Acta Anat (Basel) (1996) 1.84
The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element. Proc Natl Acad Sci U S A (1991) 1.74
New surface component of fibroblast's focal contacts identified by a monoclonal antibody. Cell (1982) 1.73
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Proc Natl Acad Sci U S A (1992) 1.70
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development (2001) 1.69
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC. Nat Struct Biol (2000) 1.67
Molecular aspects of mesenchymal-epithelial interactions. Annu Rev Cell Biol (1993) 1.63
Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice. Int J Cancer (1991) 1.61
Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo. Oncogene (1995) 1.61
Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. Cancer Res (2001) 1.60
E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice. Gastroenterology (2000) 1.57
Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis. J Cell Biol (1998) 1.56
Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility. Oncogene (1999) 1.55
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation. J Cell Biol (2001) 1.52
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr Opin Cell Biol (1994) 1.48
Corrugated attachment membrane in WI-38 fibroblasts: alternating fibronectin fibers and actin-containing focal contacts. Proc Natl Acad Sci U S A (1980) 1.43
Prognostic value of E-cadherin expression in 413 gastric carcinomas. Int J Cancer (1996) 1.40
Role of morphogenetic factors in metastasis of mammary carcinoma cells. Oncogene (1998) 1.38
Tuning spin-orbit coupling and superconductivity at the SrTiO{3}/LaAlO{3} interface: a magnetotransport study. Phys Rev Lett (2010) 1.36
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif. Oncogene (2001) 1.34
Mechanisms identified in the transcriptional control of epithelial gene expression. J Biol Chem (1996) 1.29
The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras. J Biol Chem (1994) 1.27
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL. J Biol Chem (2000) 1.22
Cytoplasmic aspartate aminotransferase: syncatalytic sulfhydryl group modification. J Biol Chem (1973) 1.22
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases. J Cell Biol (1996) 1.16
Sex differences in baseline neuropsychological function and concussion symptoms of collegiate athletes. Br J Sports Med (2006) 1.16
Cell adhesion in invasion and metastasis. Semin Cell Biol (1992) 1.15
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells. Proc Natl Acad Sci U S A (1995) 1.13
Expression of E-cadherin and catenins in invasive mammary carcinomas. Anticancer Res (1997) 1.10
Molecular characteristics of HGF-SF and its role in cell motility and invasion. EXS (1993) 1.10
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo. Curr Biol (1998) 1.10
Control of cell locomotion: perturbation with an antibody directed against specific glycoproteins. Cell (1985) 1.09
Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: implications for cell adhesion and signaling. Eur J Cancer (1999) 1.07
Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas. Cancer Res (1994) 1.06
Serum and urine markers of bone metabolism during the year after hip fracture. J Am Geriatr Soc (2001) 1.05
Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo. J Biol Chem (1996) 1.02
Intracellular and extracellular components involved in the formation of ventral surfaces of fibroblasts. Cold Spring Harb Symp Quant Biol (1982) 1.02
Differences of E-cadherin expression levels and patterns in primary and metastatic human lung cancer. Clin Exp Metastasis (1994) 1.02
Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development. Genomics (1994) 1.01
Clinical significance of E-cadherin as a prognostic marker in thyroid carcinomas. J Clin Endocrinol Metab (1995) 1.00
Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1. J Cell Biol (2001) 0.99
Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells. J Biol Chem (1995) 0.96
Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations. Pharmacogenetics (1996) 0.96
Identification of a transactivation function in the progesterone receptor that interacts with the TAFII110 subunit of the TFIID complex. J Biol Chem (1995) 0.96
Monoclonal antibodies inhibit the adhesion of mouse B 16 melanoma cells in vitro and block lung metastasis in vivo. Proc Natl Acad Sci U S A (1983) 0.96
[The arteria radialis superficialis. An unusual variation of the arteria radialis of man and its phylogenetic significance]. Acta Anat (Basel) (1987) 0.96
The role of E-cadherin and scatter factor in tumor invasion and cell motility. EXS (1991) 0.95
Role of HGF/SF and c-Met in morphogenesis and metastasis of epithelial cells. Ciba Found Symp (1997) 0.95
The effect of starch malabsorption on fecal short-chain fatty acid excretion in man. Scand J Gastroenterol (1988) 0.95
Endovascular treatment of intracerebral arteriovenous angiomas. Technique, indications and results. J Neuroradiol (1984) 0.94
[Schwannoid tumor of the lateral ventricle]. Neurochirurgie (1966) 0.94
Prevention of recurrent acute otitis media: chemoprophylaxis versus tympanostomy tubes. Laryngoscope (1986) 0.94
Properties and functions of scatter factor/hepatocyte growth factor and its receptor c-Met. Am J Respir Cell Mol Biol (1993) 0.94