Published in J Cell Biol on April 01, 1991
Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol (1997) 10.61
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol (2002) 8.60
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol (2010) 6.67
Identification and characterization of a fibroblast marker: FSP1. J Cell Biol (1995) 6.33
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A (2010) 6.15
TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J Cell Biol (1994) 6.00
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol (1993) 5.86
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol (1992) 5.04
A core function for p120-catenin in cadherin turnover. J Cell Biol (2003) 4.85
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. EMBO J (1995) 4.55
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J Cell Biol (1994) 4.34
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol (2000) 4.33
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc Natl Acad Sci U S A (1995) 4.28
N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol (1999) 4.20
Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J Cell Biol (1992) 4.12
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner. J Cell Biol (2001) 4.04
A novel role for p120 catenin in E-cadherin function. J Cell Biol (2002) 4.01
Repression of E-cadherin by the polycomb group protein EZH2 in cancer. Oncogene (2008) 3.92
Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion. J Cell Biol (2000) 3.88
Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes. Mol Cell Biol (1994) 3.66
p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol (2000) 3.60
Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci U S A (1991) 3.27
p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J (1993) 3.06
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol (2010) 3.02
In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J Cell Biol (1995) 2.95
Involvement of members of the cadherin superfamily in cancer. Cold Spring Harb Perspect Biol (2009) 2.89
Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol (1993) 2.84
Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma. Am J Pathol (1993) 2.74
In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. Neoplasia (1999) 2.71
The Wnt/Wg signal transducer beta-catenin controls fibronectin expression. Mol Cell Biol (1999) 2.68
E-cadherin expression in primary carcinomas of the breast and its distant metastases. Breast Cancer Res (2003) 2.61
Inhibition of beta-catenin-mediated transactivation by cadherin derivatives. Proc Natl Acad Sci U S A (1998) 2.55
A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1. Mol Biol Cell (1996) 2.39
E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am J Pathol (2000) 2.36
p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat Cell Biol (2009) 2.35
E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci U S A (1994) 2.35
Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis. Cancer Res (2011) 2.29
Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins. J Cell Biol (1997) 2.27
A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis. J Cell Biol (1991) 2.18
Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps. J Cell Biol (1994) 2.17
Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin. J Cell Biol (2003) 2.14
The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression. Breast Cancer Res (2001) 2.14
New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis. Br J Cancer (1999) 2.05
Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion. J Cell Biol (1996) 2.03
E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis. Br J Cancer (1997) 2.02
Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice. Clin Cancer Res (2008) 2.00
The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin. Mol Cell Biol (1995) 1.96
Hereditary breast cancer: new genetic developments, new therapeutic avenues. Hum Genet (2008) 1.96
Regulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherin. J Cell Biol (1991) 1.94
The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci U S A (2002) 1.92
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells. J Cell Biol (1995) 1.91
E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am J Pathol (1993) 1.89
Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA. J Cell Biol (1992) 1.89
Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer. Clin Cancer Res (2008) 1.82
Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression. J Biol Chem (2010) 1.79
Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation. J Cell Biol (1997) 1.78
Snail family regulation and epithelial mesenchymal transitions in breast cancer progression. J Mammary Gland Biol Neoplasia (2010) 1.76
The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element. Proc Natl Acad Sci U S A (1991) 1.74
Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E-cadherin. J Cell Biol (1992) 1.74
Protocadherins: a large family of cadherin-related molecules in central nervous system. EMBO J (1993) 1.72
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Proc Natl Acad Sci U S A (1992) 1.70
Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with alpha-actinin cDNA. Proc Natl Acad Sci U S A (1993) 1.69
Na,K-ATPase beta-subunit is required for epithelial polarization, suppression of invasion, and cell motility. Mol Biol Cell (2001) 1.68
N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility. J Cell Biol (2000) 1.65
NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin. EMBO J (2008) 1.62
Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation. Am J Pathol (1999) 1.61
Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces. J Cell Sci (2011) 1.59
Molecular analysis of neural crest migration. Philos Trans R Soc Lond B Biol Sci (2008) 1.56
The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activation. J Biol Chem (2008) 1.53
Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin). J Clin Invest (1996) 1.49
The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors. Mol Cell Biol (1995) 1.49
p120, a p120-related protein (p100), and the cadherin/catenin complex. J Cell Biol (1995) 1.48
Cadherin-11 increases migration and invasion of prostate cancer cells and enhances their interaction with osteoblasts. Cancer Res (2010) 1.46
Cross talk between adhesion molecules: control of N-cadherin activity by intracellular signals elicited by beta1 and beta3 integrins in migrating neural crest cells. J Cell Biol (1997) 1.45
Wnt/beta-catenin signaling and small molecule inhibitors. Curr Pharm Des (2013) 1.44
Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling. J Biol Chem (2009) 1.44
Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis. Proc Natl Acad Sci U S A (2001) 1.43
Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis. J Exp Med (2007) 1.42
Activated androgen receptor downregulates E-cadherin gene expression and promotes tumor metastasis. Mol Cell Biol (2008) 1.41
Tissue architecture: the ultimate regulator of epithelial function? Philos Trans R Soc Lond B Biol Sci (1998) 1.40
Discovering the molecular components of intercellular junctions--a historical view. Cold Spring Harb Perspect Biol (2009) 1.39
Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis. Breast Cancer Res (2000) 1.38
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J Exp Med (1995) 1.37
Small RNA and transcriptional upregulation. Wiley Interdiscip Rev RNA (2011) 1.36
Suppression of tumorigenicity by plakoglobin: an augmenting effect of N-cadherin. J Cell Biol (1996) 1.36
Soluble E-cadherin fragments increased in circulation of cancer patients. Br J Cancer (1994) 1.36
Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors. Breast Cancer Res (2007) 1.33
Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract. Virchows Arch (2005) 1.33
E-cadherin's dark side: possible role in tumor progression. Biochim Biophys Acta (2012) 1.32
CDO: an oncogene-, serum-, and anchorage-regulated member of the Ig/fibronectin type III repeat family. J Cell Biol (1997) 1.32
In utero exposure to diethylstilbestrol (DES) or bisphenol-A (BPA) increases EZH2 expression in the mammary gland: an epigenetic mechanism linking endocrine disruptors to breast cancer. Horm Cancer (2010) 1.29
Syndecan expression regulates cell morphology and growth of mouse mammary epithelial tumor cells. Proc Natl Acad Sci U S A (1992) 1.29
p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression. J Cell Biol (2008) 1.28
Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells. Br J Cancer (1992) 1.28
Altered expression of E-cadherin in gastric cancer tissues and carcinomatous fluid. Br J Cancer (1992) 1.27
Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome. Br J Cancer (1995) 1.26
The catalytic activity of the Src family kinases is required to disrupt cadherin-dependent cell-cell contacts. Mol Biol Cell (2000) 1.26
The tumor-suppressor function of E-cadherin. Am J Hum Genet (1998) 1.25
Expression of the E-cadherin-catenin cell adhesion complex in primary squamous cell carcinomas of the head and neck and their nodal metastases. Br J Cancer (1997) 1.25
Expression of E-cadherin and beta-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survival. World J Gastroenterol (2002) 1.25
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (1987) 49.88
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science (1989) 31.55
A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. J Immunol (1979) 16.56
Mutations in the p53 gene occur in diverse human tumour types. Nature (1989) 13.62
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst (1973) 11.26
A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst (1973) 10.64
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell (1988) 10.29
Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature (1987) 10.21
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J (1989) 10.05
Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature (1983) 9.28
Prevalence of ras gene mutations in human colorectal cancers. Nature (1987) 9.23
Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (1990) 8.32
p53: a frequent target for genetic abnormalities in lung cancer. Science (1989) 7.51
Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature (1987) 7.23
Classification of human colorectal adenocarcinoma cell lines. Cancer Res (1976) 7.00
A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int J Cancer (1976) 6.48
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol (1989) 6.31
Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells. J Cell Biol (1985) 6.09
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature (1987) 5.46
Breast tumor cell lines from pleural effusions. J Natl Cancer Inst (1974) 5.39
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature (1990) 5.13
Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells. Proc Natl Acad Sci U S A (1983) 5.05
Expressed recombinant cadherins mediate cell sorting in model systems. Cell (1988) 4.97
Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue. Cell (1983) 4.81
Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: its identity in the cadherin gene family. J Cell Biol (1988) 4.71
Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro (1978) 4.67
The gene for familial polyposis coli maps to the long arm of chromosome 5. Science (1987) 4.48
Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J Natl Cancer Inst (1977) 4.35
Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res (1989) 4.34
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science (1988) 4.26
Immunofluorescent staining of keratin fibers in cultured cells. Cell (1978) 4.25
Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science (1988) 4.15
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol (1990) 4.05
The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion. EMBO J (1987) 4.00
Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology. Lab Invest (1983) 3.91
Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. Cell (1989) 3.81
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol (1985) 3.77
Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development. Nature (1989) 3.75
Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene. Science (1990) 3.58
Visualization of a system of filaments 7-10 nm thick in cultured cells of an epithelioid line (Pt K2) by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1977) 3.52
Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma. Nature (1987) 3.46
Uvomorulin: a nonintegral membrane protein of early mouse embryo. Proc Natl Acad Sci U S A (1983) 3.42
Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res (1988) 3.22
Rabbit antiserum against a purified surface glycoprotein decompacts mouse preimplantation embryos and reacts with specific adult tissues. Exp Cell Res (1984) 3.20
Cell-cell interactions in early embryogenesis: a molecular approach to the role of calcium. Cell (1981) 3.18
Early epochal maps of two different cell adhesion molecules. Proc Natl Acad Sci U S A (1983) 3.06
Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations. Lab Invest (1985) 3.03
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell (1990) 3.02
A-CAM: a 135-kD receptor of intercellular adherens junctions. I. Immunoelectron microscopic localization and biochemical studies. J Cell Biol (1986) 2.98
Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol (1981) 2.94
Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules. Eur J Cell Biol (1990) 2.77
Human breast carcinoma cells in continuous culture: a review. Cancer Res (1978) 2.73
Linear organization of the liver cell adhesion molecule L-CAM. Proc Natl Acad Sci U S A (1984) 2.62
Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody. Cell (1983) 2.56
Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules. Proc Natl Acad Sci U S A (1988) 2.55
Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer. Nature (1988) 2.47
A monoclonal antibody disrupting calcium-dependent cell-cell adhesion of brain tissues: possible role of its target antigen in animal pattern formation. Proc Natl Acad Sci U S A (1985) 2.44
The calcium-dependent cell-cell adhesion system regulates inner cell mass formation and cell surface polarization in early mouse development. Cell (1983) 2.29
Human pancreatic carcinoma (MIA PaCa-2) in continuous culture: sensitivity to asparaginase. Int J Cancer (1977) 2.12
Neural cadherin: role in selective cell-cell adhesion. Science (1989) 2.00
Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma. Proc Natl Acad Sci U S A (1990) 1.90
Epithelial cell cultures from normal and cancerous human tissues. J Natl Cancer Inst (1976) 1.86
Tumor and lymphoid cell lines from a patient with carcinoma of the colon for a cytotoxicity model. Cancer Res (1978) 1.86
A human tissue culture cell line from a transitional cell tumour of the urinary bladder: growth, chromosone pattern and ultrastructure. Br J Cancer (1970) 1.81
The structure and function of intercellular junctions in cancer. Adv Cancer Res (1976) 1.79
Unstable expression of E-cadherin adhesion molecules in metastatic ovarian tumor cells. Jpn J Cancer Res (1989) 1.77
Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. Proc Natl Acad Sci U S A (1988) 1.76
Characterization of the WIDR: a human colon carcinoma cell line. In Vitro (1979) 1.69
Allelic losses of chromosomes 9, 11, and 17 in human bladder cancer. Cancer Res (1990) 1.67
Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues. J Cell Biol (1989) 1.66
Expression of the cell-cell adhesion glycoprotein cell-CAM 120/80 in normal human tissues and tumors. Am J Pathol (1989) 1.63
Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines. Cancer Res (1988) 1.56
Characterization and chromosomal localization of the gene encoding the human cell adhesion molecule uvomorulin. Differentiation (1988) 1.55
Tumor dedifferentiation: an important step in tumor invasion. Clin Exp Metastasis (1986) 1.54
Cytokeratins in normal lung and lung carcinomas. I. Adenocarcinomas, squamous cell carcinomas and cultured cell lines. Virchows Arch B Cell Pathol Incl Mol Pathol (1984) 1.53
Vimentin rather than keratin expression in some hormone-independent breast cancer cell lines and in oncogene-transformed mammary epithelial cells. Cancer Res (1989) 1.49
Cytokeratins in normal and malignant transitional epithelium. Maintenance of expression of urothelial differentiation features in transitional cell carcinomas and bladder carcinoma cell culture lines. Am J Pathol (1988) 1.47
Desmosomal proteins: new markers for identification and classification of tumors. Lab Invest (1986) 1.37
Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen B (CTRB) with the help of two overlapping deletions on the long arm of chromosome 16. Cytogenet Cell Genet (1989) 1.31
A new in vivo model to study invasion and metastasis of human bladder carcinoma. Cancer Res (1987) 1.23
Stages in neoplastic transformation of adult epithelial cells by 7,12-dimethylbenz(a)anthracene in vitro. Cancer Res (1977) 1.19
Cellular heterogeneity in a tissue culture cell line derived from a human bladder carcinoma. Br J Cancer (1983) 1.10
Relationship between extracellular matrix interactions and degree of differentiation in human colon carcinoma cell lines. Cancer Res (1989) 1.08
The invasive phenotypes. Cancer Metastasis Rev (1990) 0.99
Steroid/thyroid receptor-like proteins with oncogenic potential: a review. Cancer Res (1990) 0.94
[Pathologic findings in colorectal cancers and discussion of their significance for tumor therapy according to stage]. Wien Klin Wochenschr (1987) 0.92
[Epithelial tumor markers]. Verh Dtsch Ges Pathol (1986) 0.90
[Colon carcinoma. Preoperative CEA, tumor differentiation and prognosis]. Dtsch Med Wochenschr (1987) 0.85
Identification of exposed surface glycoproteins of four human bladder carcinoma cell lines. Biochim Biophys Acta (1983) 0.83
Functional interaction of beta-catenin with the transcription factor LEF-1. Nature (1996) 15.88
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell (2001) 8.41
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science (1998) 8.27
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol (1989) 6.31
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol (1993) 5.86
Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. Biochim Biophys Acta (1994) 5.81
Requirement for beta-catenin in anterior-posterior axis formation in mice. J Cell Biol (2000) 4.36
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J Cell Biol (1994) 4.34
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol (1990) 4.05
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol (1985) 3.77
Detection of human immunodeficiency virus type 1 provirus in mononuclear cells by in situ polymerase chain reaction. N Engl J Med (1992) 3.64
New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev (2001) 3.63
Double-blind, placebo-controlled food challenge (DBPCFC) as an office procedure: a manual. J Allergy Clin Immunol (1988) 3.57
The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol (2003) 3.06
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. Nature (1996) 3.00
Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol (1993) 2.84
In vivo distribution and turnover of fluorescently labeled actin microinjected into human fibroblasts. Proc Natl Acad Sci U S A (1979) 2.71
Microinjection of fluorescently labeled proteins into living cells with emphasis on cytoskeletal proteins. Int Rev Cytol (1982) 2.70
E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res (1991) 2.67
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. EMBO J (1992) 2.65
Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody. Cell (1983) 2.56
E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res (1993) 2.55
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. II. The role of ATP. J Cell Biol (1977) 2.54
The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells. J Cell Biol (1993) 2.53
Inhibitory action of transforming growth factor beta on endothelial cells. Proc Natl Acad Sci U S A (1987) 2.50
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses. J Cell Biol (2000) 2.48
Stress fiber sarcomeres of fibroblasts are contractile. Cell (1980) 2.45
E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci U S A (1994) 2.35
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart. J Cell Biol (1996) 2.27
SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A. J Biol Chem (1993) 2.17
Essential role of Gab1 for signaling by the c-Met receptor in vivo. J Cell Biol (2000) 1.97
Biochemical interactions in the wnt pathway. Biochim Biophys Acta (2000) 1.96
V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift. J Cell Biol (1995) 1.92
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells. J Cell Biol (1995) 1.91
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland. J Cell Biol (1995) 1.91
Transforming growth factor-beta inhibits endothelial cell proliferation. Biochem Biophys Res Commun (1986) 1.86
Epithelial-mesenchymal transitions in cancer progression. Acta Anat (Basel) (1996) 1.84
Snail promotes Wnt target gene expression and interacts with beta-catenin. Oncogene (2008) 1.76
The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element. Proc Natl Acad Sci U S A (1991) 1.74
New surface component of fibroblast's focal contacts identified by a monoclonal antibody. Cell (1982) 1.73
Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme. Int J Radiat Oncol Biol Phys (1998) 1.71
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Proc Natl Acad Sci U S A (1992) 1.70
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development (2001) 1.69
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC. Nat Struct Biol (2000) 1.67
Piccolo, a presynaptic zinc finger protein structurally related to bassoon. Neuron (2000) 1.66
Molecular aspects of mesenchymal-epithelial interactions. Annu Rev Cell Biol (1993) 1.63
Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice. Int J Cancer (1991) 1.61
Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo. Oncogene (1995) 1.61
Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. Cancer Res (2001) 1.60
E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice. Gastroenterology (2000) 1.57
A cysteine-rich collagenous protein from bovine placenta. Isolation of its constituent polypeptide chains and some properties of the non-denatured protein. Eur J Biochem (1981) 1.56
Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis. J Cell Biol (1998) 1.56
Monoacetoxyscirpenol. A new mycotoxin produced by Fusarium roseum Gibbosum. J Agric Food Chem (1976) 1.55
Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility. Oncogene (1999) 1.55
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation. J Cell Biol (2001) 1.52
Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential. J Biol Chem (2000) 1.50
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr Opin Cell Biol (1994) 1.48
Corrugated attachment membrane in WI-38 fibroblasts: alternating fibronectin fibers and actin-containing focal contacts. Proc Natl Acad Sci U S A (1980) 1.43
Molecular mechanisms leading to cell junction (cadherin) deficiency in invasive carcinomas. Semin Cancer Biol (1993) 1.41
Prognostic value of E-cadherin expression in 413 gastric carcinomas. Int J Cancer (1996) 1.40
RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2. Mol Cell Biol (1998) 1.39
Role of morphogenetic factors in metastasis of mammary carcinoma cells. Oncogene (1998) 1.38
Iron in prenatal multivitamin/multimineral supplements. Bioavailability. J Reprod Med (1998) 1.38
Tuning spin-orbit coupling and superconductivity at the SrTiO{3}/LaAlO{3} interface: a magnetotransport study. Phys Rev Lett (2010) 1.36
Rapid flow cytometric test for the diagnosis of membrane cytoskeleton-associated haemolytic anaemia. Br J Haematol (2000) 1.34
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif. Oncogene (2001) 1.34
Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells. J Cell Sci Suppl (1993) 1.34
Mechanisms identified in the transcriptional control of epithelial gene expression. J Biol Chem (1996) 1.29
The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras. J Biol Chem (1994) 1.27
Nutritional interventions for preventing and treating pressure ulcers. Cochrane Database Syst Rev (2003) 1.26
Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix. Eur J Cell Biol (1996) 1.25
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL. J Biol Chem (2000) 1.22
Cytoplasmic aspartate aminotransferase: syncatalytic sulfhydryl group modification. J Biol Chem (1973) 1.22
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases. J Cell Biol (1996) 1.16
Sex differences in baseline neuropsychological function and concussion symptoms of collegiate athletes. Br J Sports Med (2006) 1.16
Cell adhesion in invasion and metastasis. Semin Cell Biol (1992) 1.15
Ultrastructural localization of extracellular matrix proteins in liver biopsies using ultracryomicrotomy and immuno-gold labelling. Histopathology (1990) 1.13