Published in Proc Natl Acad Sci U S A on June 01, 1983
Development of cell surface linkage complexes in cultured fibroblasts. J Cell Biol (1985) 3.59
Platelet-collagen adhesion: inhibition by a monoclonal antibody that binds glycoprotein IIb. J Cell Biol (1984) 1.34
Homing of hemopoietic precursor cells to the embryonic thymus: characterization of an invasive mechanism induced by chemotactic peptides. J Cell Biol (1986) 1.24
Invasive behavior of mouse sarcoma cells is inhibited by blocking a 37,000-dalton plasma membrane glycoprotein with Fab fragments. Proc Natl Acad Sci U S A (1984) 1.01
Blocking of lung endothelial cell adhesion molecule-1 (Lu-ECAM-1) inhibits murine melanoma lung metastasis. J Clin Invest (1992) 0.87
Monoclonal antibodies that prevent adhesion of B 16 melanoma cells and reduce metastases in mice: crossreaction with human tumor cells. Proc Natl Acad Sci U S A (1983) 0.83
Effects of altering surface glycoprotein composition on metastatic colonisation potential of murine mammary tumour cells. Br J Cancer (1987) 0.75
Metastasis results from preexisting variant cells within a malignant tumor. Science (1977) 6.47
The pathogenesis of cancer metastasis. Nature (1980) 5.74
Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res (1975) 3.59
Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proc Natl Acad Sci U S A (1980) 3.38
A monoclonal antibody detaches embryonic skeletal muscle from extracellular matrices. J Cell Biol (1982) 3.23
Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells. Proc Natl Acad Sci U S A (1981) 1.87
New surface component of fibroblast's focal contacts identified by a monoclonal antibody. Cell (1982) 1.73
Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells. Proc Natl Acad Sci U S A (1980) 1.65
Selection and altered properties of brain-colonising metastatic melanoma. Nature (1978) 1.58
Interactions of tumor cells with vascular endothelial cell monolayers: a model for metastatic invasion. Proc Natl Acad Sci U S A (1979) 1.57
Metastasis: a review of recent advances. Cancer Res (1957) 1.43
Liver-colonizing melanoma cells selected from B-16 melanoma. Int J Cancer (1979) 1.17
Immune response to the src gene product in mice bearing tumors induced by injection of avian sarcoma virus-transformed mouse cells. J Virol (1979) 1.11
Syngeneic antitumour antibodies in rats: clearance of cell-bound antibody in vivo and in vitro. Br J Cancer (1982) 0.85
Monoclonal anti-MM46 antibody:ricin A chain conjugate: in vitro and in vivo antitumor activity. Cancer Res (1982) 0.84
Functional interaction of beta-catenin with the transcription factor LEF-1. Nature (1996) 15.88
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol (1991) 8.60
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell (2001) 8.41
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science (1998) 8.27
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol (1989) 6.31
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol (1993) 5.86
Requirement for beta-catenin in anterior-posterior axis formation in mice. J Cell Biol (2000) 4.36
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. J Cell Biol (1994) 4.34
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol (1990) 4.05
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol (1985) 3.77
New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev (2001) 3.63
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. Nature (1996) 3.00
Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol (1993) 2.84
In vivo distribution and turnover of fluorescently labeled actin microinjected into human fibroblasts. Proc Natl Acad Sci U S A (1979) 2.71
Microinjection of fluorescently labeled proteins into living cells with emphasis on cytoskeletal proteins. Int Rev Cytol (1982) 2.70
E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res (1991) 2.67
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. EMBO J (1992) 2.65
Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody. Cell (1983) 2.56
E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res (1993) 2.55
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. II. The role of ATP. J Cell Biol (1977) 2.54
The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells. J Cell Biol (1993) 2.53
Inhibitory action of transforming growth factor beta on endothelial cells. Proc Natl Acad Sci U S A (1987) 2.50
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses. J Cell Biol (2000) 2.48
Stress fiber sarcomeres of fibroblasts are contractile. Cell (1980) 2.45
E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci U S A (1994) 2.35
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart. J Cell Biol (1996) 2.27
Essential role of Gab1 for signaling by the c-Met receptor in vivo. J Cell Biol (2000) 1.97
V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift. J Cell Biol (1995) 1.92
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells. J Cell Biol (1995) 1.91
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland. J Cell Biol (1995) 1.91
Transforming growth factor-beta inhibits endothelial cell proliferation. Biochem Biophys Res Commun (1986) 1.86
Epithelial-mesenchymal transitions in cancer progression. Acta Anat (Basel) (1996) 1.84
The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element. Proc Natl Acad Sci U S A (1991) 1.74
New surface component of fibroblast's focal contacts identified by a monoclonal antibody. Cell (1982) 1.73
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. Proc Natl Acad Sci U S A (1992) 1.70
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development (2001) 1.69
Differential expression of CD44 splice variants in intestinal- and diffuse-type human gastric carcinomas and normal gastric mucosa. Cancer Res (1993) 1.68
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC. Nat Struct Biol (2000) 1.67
Molecular aspects of mesenchymal-epithelial interactions. Annu Rev Cell Biol (1993) 1.63
Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice. Int J Cancer (1991) 1.61
Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo. Oncogene (1995) 1.61
Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. Cancer Res (2001) 1.60
E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice. Gastroenterology (2000) 1.57
Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis. J Cell Biol (1998) 1.56
Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility. Oncogene (1999) 1.55
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation. J Cell Biol (2001) 1.52
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr Opin Cell Biol (1994) 1.48
Corrugated attachment membrane in WI-38 fibroblasts: alternating fibronectin fibers and actin-containing focal contacts. Proc Natl Acad Sci U S A (1980) 1.43
Prognostic value of E-cadherin expression in 413 gastric carcinomas. Int J Cancer (1996) 1.40
Role of morphogenetic factors in metastasis of mammary carcinoma cells. Oncogene (1998) 1.38
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif. Oncogene (2001) 1.34
Mechanisms identified in the transcriptional control of epithelial gene expression. J Biol Chem (1996) 1.29
The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras. J Biol Chem (1994) 1.27
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL. J Biol Chem (2000) 1.22
Cytoplasmic aspartate aminotransferase: syncatalytic sulfhydryl group modification. J Biol Chem (1973) 1.22
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases. J Cell Biol (1996) 1.16
Cell adhesion in invasion and metastasis. Semin Cell Biol (1992) 1.15
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells. Proc Natl Acad Sci U S A (1995) 1.13
Molecular characteristics of HGF-SF and its role in cell motility and invasion. EXS (1993) 1.10
Expression of E-cadherin and catenins in invasive mammary carcinomas. Anticancer Res (1997) 1.10
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo. Curr Biol (1998) 1.10
Control of cell locomotion: perturbation with an antibody directed against specific glycoproteins. Cell (1985) 1.09
Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: implications for cell adhesion and signaling. Eur J Cancer (1999) 1.07
Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas. Cancer Res (1994) 1.06
Intracellular and extracellular components involved in the formation of ventral surfaces of fibroblasts. Cold Spring Harb Symp Quant Biol (1982) 1.02
Differences of E-cadherin expression levels and patterns in primary and metastatic human lung cancer. Clin Exp Metastasis (1994) 1.02
Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development. Genomics (1994) 1.01
Clinical significance of E-cadherin as a prognostic marker in thyroid carcinomas. J Clin Endocrinol Metab (1995) 1.00
Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1. J Cell Biol (2001) 0.99
Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells. J Biol Chem (1995) 0.96
The role of E-cadherin and scatter factor in tumor invasion and cell motility. EXS (1991) 0.95
Properties and functions of scatter factor/hepatocyte growth factor and its receptor c-Met. Am J Respir Cell Mol Biol (1993) 0.94
Analysis of the E-cadherin and P-cadherin promoters in murine keratinocyte cell lines from different stages of mouse skin carcinogenesis. Mol Carcinog (1997) 0.93
Interaction of integral and peripheral membrane proteins: affinity labeling of yeast cytochrome oxidase by modified yeast cytochrome c. Proc Natl Acad Sci U S A (1976) 0.92
Deletion of the E-cadherin gene in hepatitis B virus-positive Chinese hepatocellular carcinomas. Hepatology (1993) 0.92
beta-catenin-dependent and -independent effects of DeltaN-plakoglobin on epidermal growth and differentiation. Mol Cell Biol (2004) 0.92
Reversion of the transformed phenotype of B16 mouse melanoma: involvement of an 83 kd cell surface glycoprotein in specific growth inhibition. Cell (1986) 0.92
Characterization of glycosylphosphatidylinositol-linked molecule CD55/decay-accelerating factor as the receptor for antibody SC-1-induced apoptosis. Cancer Res (1999) 0.90
Plakoglobin is essential for myocardial compliance but dispensable for myofibril insertion into adherens junctions. J Cell Biochem (1999) 0.89
Importance of different CD44v6 expression in human gastric intestinal and diffuse type cancers for metastatic lymphogenic spreading. J Mol Med (Berl) (1995) 0.89
Monoclonal antibodies NORM-1 and NORM-2 induce more normal behavior of tumor cells in vitro and reduce tumor growth in vivo. Cell (1985) 0.88
Natural IgM antibodies, the ignored weapons in tumour immunity. Histol Histopathol (2004) 0.87
Regulation of the new coexpressed CD55 (decay-accelerating factor) receptor on stomach carcinoma cells involved in antibody SC-1-induced apoptosis. Lab Invest (2001) 0.87
Reactivity of monoclonal antibodies specific for H-2 antigenic determinants with cells of wild mice. Immunol Rev (1979) 0.86
Muscle G-actin is an inhibitor of ATP-induced erythrocyte ghost shape changes and endocytosis. Biochem Biophys Res Commun (1977) 0.86
E-Cadherin in human brain tumours: loss of immunoreactivity in malignant meningiomas. Virchows Arch (1998) 0.86
Cell-cell adhesion in invasion and metastasis of carcinomas. Cancer Treat Res (1994) 0.85
ATP-induced endocytosis in human erythrocyte ghosts. Characterization of the process and isolation of the endocytosed vesicles. J Biol Chem (1979) 0.85
Hepatocyte growth factor/scatter factor (HGF/SF) signals via the STAT3/APRF transcription factor in human hepatoma cells and hepatocytes. FEBS Lett (1997) 0.85
Transforming growth factor beta as a potent promoter in two-stage BALB/c 3T3 cell transformation. Cancer Res (1988) 0.84
Comparison of human hemoglobin A carrying glutathione as a mixed disulfide with the naturally occurring human hemoglobin A. Biochemistry (1973) 0.84
Monoclonal antibodies which prevent experimental lung metastases. Interference with the adhesion of tumour cells to laminin. FEBS Lett (1984) 0.83
Monoclonal antibodies that prevent adhesion of B 16 melanoma cells and reduce metastases in mice: crossreaction with human tumor cells. Proc Natl Acad Sci U S A (1983) 0.83
Association between coated vesicles and microtubules. Exp Cell Res (1983) 0.83
Molecular IgV(H) analysis demonstrates highly somatic mutated B cells in synovialitis of osteoarthritis: a degenerative disease is associated with a specific, not locally generated immune response. Lab Invest (1999) 0.82