Published in Biochemistry on May 28, 1996
Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay. Mol Cell Biol (2002) 5.80
The hDcp2 protein is a mammalian mRNA decapping enzyme. Proc Natl Acad Sci U S A (2002) 3.97
Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain? EMBO J (1998) 2.31
A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase. EMBO J (1998) 1.66
Multiple Nudix family proteins possess mRNA decapping activity. RNA (2013) 0.97
Characterization of active-site residues in diadenosine tetraphosphate hydrolase from Lupinus angustifolius. Biochem J (2001) 0.89
Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2). Nucleic Acids Res (2007) 0.89
Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein. Nucleic Acids Res (2000) 0.89
A comprehensive bioinformatics analysis of the Nudix superfamily in Arabidopsis thaliana. Comp Funct Genomics (2009) 0.86
Cloning and expression of diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase from Lupinus angustifolius L. Biochem J (1998) 0.86
YZGD from Paenibacillus thiaminolyticus, a pyridoxal phosphatase of the HAD (haloacid dehalogenase) superfamily and a versatile member of the Nudix (nucleoside diphosphate x) hydrolase superfamily. Biochem J (2006) 0.84
The C-terminal domain of Escherichia coli MutY is involved in DNA binding and glycosylase activities. Nucleic Acids Res (2003) 0.83
Significance of the conserved amino acid sequence for human MTH1 protein with antimutator activity. Nucleic Acids Res (1997) 0.83
Functional and structural characterization of DR_0079 from Deinococcus radiodurans, a novel Nudix hydrolase with a preference for cytosine (deoxy)ribonucleoside 5'-Di- and triphosphates. Biochemistry (2008) 0.80
ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins. Proc Natl Acad Sci U S A (1986) 5.55
The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes. J Biol Chem (1996) 5.08
Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturation. J Magn Reson B (1995) 4.93
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature (2001) 4.75
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. Proc Natl Acad Sci U S A (1981) 4.14
Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4. J Biol Chem (1972) 4.11
Immunochemical properties of the staphylococcal poly-N-acetylglucosamine surface polysaccharide. Infect Immun (2002) 3.14
Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases. J Mol Biol (1974) 2.79
Spinach leaf phosphoenolpyruvate carboxylase: purification, properties, and kinetic studies. Arch Biochem Biophys (1974) 2.46
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Zinc in DNA polymerases. Biochem Biophys Res Commun (1971) 2.15
Aspects of enzyme mechanisms studies by nuclear spin relazation induced by paramagnetic probes. Adv Enzymol Relat Areas Mol Biol (1970) 1.90
On the fidelity of DNA replication: manganese mutagenesis in vitro. Biochemistry (1985) 1.90
Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase. Biochemistry (1989) 1.85
Studies on the mutator gene, mutT of Escherichia coli. Molecular cloning of the gene, purification of the gene product, and identification of a novel nucleoside triphosphatase. J Biol Chem (1988) 1.84
Purification and determination of the structure of capsular polysaccharide of Vibrio vulnificus M06-24. J Bacteriol (1992) 1.81
Kinetic and magnetic resonance studies of the pyruvate kinase reaction. II. Complexes of enzyme, metal, and substrates. J Biol Chem (1966) 1.79
The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family. Nat Struct Biol (2001) 1.79
Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance. J Biol Chem (1999) 1.74
Structure and dynamics of a denatured 131-residue fragment of staphylococcal nuclease: a heteronuclear NMR study. Biochemistry (1994) 1.55
The enzymology of virus-infected bacteria. X. A biochemical-genetic study of the deoxynucleotide kinase induced by wild type and amber mutants of phage T4. J Biol Chem (1967) 1.54
Environments and mechanistic roles of the tyrosine residues of delta 5-3-ketosteroid isomerase. Biochemistry (1993) 1.53
Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: correlation of potencies as phase 2 enzyme inducers and radical scavengers. J Med Chem (1998) 1.53
Characterization of the mutT nucleoside triphosphatase of Escherichia coli. J Biol Chem (1991) 1.52
Structural and antigenic types of cell wall polysaccharides from viridans group streptococci with receptors for oral actinomyces and streptococcal lectins. Infect Immun (1997) 1.49
Kinetic and magnetic resonance studies of active-site mutants of staphylococcal nuclease: factors contributing to catalysis. Biochemistry (1987) 1.46
NMR docking of a substrate into the X-ray structure of staphylococcal nuclease. Proteins (1992) 1.46
Lectin recognition of host-like saccharide motifs in streptococcal cell wall polysaccharides. Glycobiology (1995) 1.46
Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. Biochemistry (1994) 1.46
Characterization of the mutX gene of Streptococcus pneumoniae as a homologue of Escherichia coli mutT, and tentative definition of a catalytic domain of the dGTP pyrophosphohydrolases. Mol Microbiol (1994) 1.40
The Nudix hydrolases of Deinococcus radiodurans. Mol Microbiol (2001) 1.38
The purification and properties of deoxyguanosine triphosphate triphosphohydrolase from Escherichia coli. J Biol Chem (1988) 1.38
Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation. Biochemistry (1997) 1.35
NMR evidence for the participation of a low-barrier hydrogen bond in the mechanism of delta 5-3-ketosteroid isomerase. Proc Natl Acad Sci U S A (1996) 1.33
The role of metal ions in the mechanisms of DNA and RNA polymerases. CRC Crit Rev Biochem (1979) 1.33
Stuies on the interaction of substrate and monovalent and divalent cations with pyruvate kinase. Biochemistry (1966) 1.33
Mechanism of malic enzyme from pigeon liver. Magnetic resonance and kinetic studies of the role of Mn2+. J Biol Chem (1976) 1.32
Influence of local nucleotide sequence on substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro. Biochemistry (1983) 1.32
Proton magnetic relaxation studies of the interaction of D-xylose and xylitol with D-xylose isomerase. Characterization of metal-enzyme-substrate interactions. J Biol Chem (1975) 1.27
Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I. J Biol Chem (1975) 1.27
Assay for the Killing Properties of T2 Bacteriophage and Their "Ghosts". J Bacteriol (1965) 1.27
The interaction of DNA polymerase III and the product of the Escherichia coli mutator gene, mutD. J Biol Chem (1984) 1.26
The mechanism of aconitase action. I. Preparation, physical properties of the enzyme, and activation by iron (II). J Biol Chem (1971) 1.25
Escherichia coli deoxyribonucleic acid polymerase I, a zinc metalloenzyme. Nuclear quadrupolar relaxation studies of the role of bound zinc. J Biol Chem (1973) 1.24
4-Oxalocrotonate tautomerase: pH dependence of catalysis and pKa values of active site residues. Biochemistry (1996) 1.24
Kinetic and magnetic resonance studies of effects of genetic substitution of a Ca2+-liganding amino acid in staphylococcal nuclease. Biochemistry (1986) 1.24
Conformation of deoxynucleoside triphosphate substrates on DNA polymerase I from Escherichia coli as determined by nuclear magnetic relaxation. J Biol Chem (1975) 1.23
The enzymology of virus-infected bacteria. VII. A new deoxyribonucleic acid polymerase induced by bacteriophage T5. J Biol Chem (1965) 1.23
Studies on the biochemical basis of spontaneous mutation. V. Effect of temperature on mutation frequency. J Mol Biol (1977) 1.23
Catalytic role of the amino-terminal proline in 4-oxalocrotonate tautomerase: affinity labeling and heteronuclear NMR studies. Biochemistry (1996) 1.20
The mechanism of Escherichia coli deoxyribonucleic acid polymerase I. Magnetic resonance and kinetic studies of the role of metals. J Biol Chem (1972) 1.17
Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase. Biochemistry (1995) 1.17
Orf186 represents a new member of the Nudix hydrolases, active on adenosine(5')triphospho(5')adenosine, ADP-ribose, and NADH. J Biol Chem (1998) 1.16
Structures of enzyme-bound metal-nucleotide complexes in the phosphoryl transfer reaction of muscle pyruvate kinase. 31P NMR studies with magnesium and kinetic studies with chromium nucleotides. J Biol Chem (1977) 1.15
Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP. J Biol Chem (2000) 1.13
Studies on the synthesis of deoxyribonucleic acid. I. Further purification and properties of the deoxyribonucleic acid polymerase induced by infection of Escherichia coli with bacteriophage T5. J Biol Chem (1968) 1.13
Escherichia coli orf17 codes for a nucleoside triphosphate pyrophosphohydrolase member of the MutT family of proteins. Cloning, purification, and characterization of the enzyme. J Biol Chem (1996) 1.13
Kinetic and magnetic resonance studies of the mechanism of D-xylose isomerase. I. Binary and ternary complexes with manganese(II), substrates, and inhibitors. J Biol Chem (1972) 1.12
Electron paramagnetic resonance, 1-H, and 13C nuclear magnetic resonance studies of the interaction of manganese and bicarbonate with ribulose 1, 5-diphosphate carboxylase. J Biol Chem (1974) 1.12
Cloning, purification, and properties of a novel NADH pyrophosphatase. Evidence for a nucleotide pyrophosphatase catalytic domain in MutT-like enzymes. J Biol Chem (1995) 1.11
Combined effects of two mutations of catalytic residues on the ketosteroid isomerase reaction. Biochemistry (1990) 1.09
A novel GDP-mannose mannosyl hydrolase shares homology with the MutT family of enzymes. J Biol Chem (1995) 1.09
15N NMR relaxation studies of free and inhibitor-bound 4-oxalocrotonate tautomerase: backbone dynamics and entropy changes of an enzyme upon inhibitor binding. Biochemistry (1996) 1.09
Identification and characterization of the Nudix hydrolase from the Archaeon, Methanococcus jannaschii, as a highly specific ADP-ribose pyrophosphatase. J Biol Chem (1998) 1.09
Catalytic mechanism of an active-site mutant (D38N) of delta 5-3-ketosteroid isomerase. Direct spectroscopic evidence for dienol intermediates. Biochemistry (1991) 1.08
Hydrogen bonding at the active site of delta 5-3-ketosteroid isomerase. Biochemistry (1997) 1.08
Studies of the mechanism of the delta 5-3-ketosteroid isomerase reaction by substrate, solvent, and combined kinetic deuterium isotope effects on wild-type and mutant enzymes. Biochemistry (1990) 1.08
Nuclear relaxation measurements of the geometry of enzyme-bound substrates and analogs. Methods Enzymol (1978) 1.07
NMR studies of conformations and interactions of substrates and ribonucleotide templates bound to the large fragment of DNA polymerase I. Biochemistry (1986) 1.07
Water exchange filter with improved sensitivity (WEX II) to study solvent-exchangeable protons. Application to the consensus zinc finger peptide CP-1. J Magn Reson B (1996) 1.07
Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate. Biochemistry (1998) 1.06
Vaccinia DNA topoisomerase I: kinetic evidence for general acid-base catalysis and a conformational step. Biochemistry (1994) 1.06
Nuclear magnetic resonance studies of the function of potassium in the mechanism of pyruvate kinase. Biochemistry (1972) 1.05
Comprehensive chromatographic and spectroscopic methods for the separation and identification of intact glucosinolates. Anal Biochem (1996) 1.05
High-precision measurement of hydrogen bond lengths in proteins by nuclear magnetic resonance methods. Proteins (1999) 1.05
NMR studies of the role of hydrogen bonding in the mechanism of triosephosphate isomerase. Biochemistry (1997) 1.05
NMR studies of the MgATP binding site of adenylate kinase and of a 45-residue peptide fragment of the enzyme. Biochemistry (1985) 1.04
NMR structure of a stable "OB-fold" sub-domain isolated from staphylococcal nuclease. J Mol Biol (1995) 1.04
Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase. Biochemistry (2000) 1.03
Biochemical studies on the mutagen, 6-N-hydroxylaminopurine. Synthesis of the deoxynucleoside triphosphate and its incorporation into DNA in vitro. J Biol Chem (1986) 1.03
An antimutator deoxyribonucleic acid polymerase. I. Purification and properties of the enzyme. J Biol Chem (1976) 1.02
Proton transfer in the mechanism of triosephosphate isomerase. Biochemistry (1998) 1.02
Positioning of a spin-labeled substrate analogue into the structure of delta 5-3-ketosteroid isomerase by combined kinetic, magnetic resonance, and X-ray diffraction methods. Biochemistry (1987) 1.02
Magnetic resonance and kinetic studies of the manganese(II) ion and substrate complexes of the catalytic subunit of adenosine 3',5'-monophosphate dependent protein kinase from bovine heart. Biochemistry (1979) 1.02
Studies of the catalytic mechanism of an active-site mutant (Y14F) of delta 5-3-ketosteroid isomerase by kinetic deuterium isotope effects. Biochemistry (1991) 1.02