Published in J Cell Biol on August 01, 1977
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Physiological regulation of total tubulin and polymerized tubulin in tissues. J Cell Biol (1977) 1.03
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Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules. J Mol Biol (1974) 5.00
Immunofluorescence of mitotic spindles by using monospecific antibody against bovine brain tubulin. Science (1975) 4.63
Properties of colchicine binding protein from chick embryo brain. Interactions with vinca alkaloids and podophyllotoxin. Biochemistry (1970) 4.26
Microtubule assembly in vitro. Fed Proc (1974) 3.82
Microtubules from mammalian brain: some properties of their depolymerization products and a proposed mechanism of assembly and disassembly. Proc Natl Acad Sci U S A (1974) 3.59
A functional mitotic spindle prepared from mammalian cells in culture. Proc Natl Acad Sci U S A (1974) 2.64
The mitotic apparatus: isolation by controlled pH. J Cell Biol (1962) 2.59
Direct biochemical measurements of microtubule assembly and disassembly in Chinese hamster ovary cells. The effect of intercellular contact, cold, D2O, and N6,O2'-dibutyryl cyclic adenosine monophosphate. J Cell Biol (1975) 1.69
Changes in the organization of tubulin during meiosis in the eggs of the surf clam, Spisula solidissima. J Cell Biol (1972) 1.62
Microtubule assembly and the intracellular transport of secretory granules in pancreatic islets. Science (1976) 1.28
The stabilization of calf-brain microtubule protein by sucrose. Arch Biochem Biophys (1972) 1.10
Characteristics of sea-urchin mitotic apparatus isolated using a dimethyl sulphoxide/glycerol medium. J Cell Sci (1974) 0.86
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Radioimmunoassay for the measurement of adenosine 3',5'-cyclic phosphate. Proc Natl Acad Sci U S A (1969) 7.81
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Plasma insulin responses to oral and intravenous glucose: studies in normal and diabetic sujbjects. J Clin Invest (1967) 3.60
Growth hormone secretion during sleep. J Clin Invest (1968) 2.90
Radioimmunoassay for cyclic nucleotides. II. Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in mammalian tissues and body fluids. J Biol Chem (1972) 2.84
Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects. Diabetes (1966) 2.71
An adrenergic receptor mechanism for the control of cyclic 3'5' adenosine monophosphate synthesis in tissues. Biochem Biophys Res Commun (1967) 2.55
A new in vitro model for the study of pancreatic A and B cells. Endocrinology (1985) 2.29
Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. Diabetes (2001) 2.20
Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells. Proc Natl Acad Sci U S A (1988) 2.11
Insulin-stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. Science (1986) 2.06
High frequency of persisting or increasing islet-specific autoantibody levels after diagnosis of type 1 diabetes presenting before 40 years of age. The Belgian Diabetes Registry. Diabetes Care (2000) 2.04
Measurement of "true" glucose production rates in infancy and childhood with 6,6-dideuteroglucose. Diabetes (1977) 2.02
Stimulation of insulin secretion by theophylline. Nature (1967) 1.89
Alanine and glutamine synthesis and release from skeletal muscle. I. Glycolysis and amino acid release. J Biol Chem (1976) 1.87
Abnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acids. J Clin Invest (1965) 1.83
Immunofluorescence localization of proteins of high molecular weight along intracellular microtubules. Science (1977) 1.83
Nerve growth factor stimulates a protein kinase in PC-12 cells that phosphorylates microtubule-associated protein-2. J Biol Chem (1990) 1.82
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A (1994) 1.76
The effect of oxotremorine and atropine on cGMP and cAMP levels in mouse cerebral cortex and cerebellum. Biochem Biophys Res Commun (1970) 1.72
Closed-loop and open-loop devices for blood glucose control in normal and diabetic subjects. Diabetes (1979) 1.69
Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus. Diabetes (2001) 1.66
The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man. J Clin Invest (1976) 1.63
Alanine and glutamine synthesis and release from skeletal muscle. II. The precursor role of amino acids in alanine and glutamine synthesis. J Biol Chem (1976) 1.59
The effect of fasting, diet, and actinomycin D on insulin secretion in the rat. J Clin Invest (1970) 1.55
A method for the purification of single A, B and D cells and for the isolation of coupled cells from isolated rat islets. Diabetologia (1981) 1.54
Extra-insular beta cells associated with ductules are frequent in adult human pancreas. Diabetologia (1998) 1.54
Insulin biosynthesis. I. On the mechanism of glucose stimulation. J Biol Chem (1972) 1.54
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Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. J Clin Invest (1994) 1.48
Binding of microtubules to pituitary secretory granules and secretory granule membranes. J Cell Biol (1977) 1.46
Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft. Diabetologia (1998) 1.44
Dissociation of effects of insulin and contraction on glucose transport in rat epitrochlearis muscle. Am J Physiol (1985) 1.42
Interplay of nutrients and hormones in the regulation of insulin release. Endocrinology (1985) 1.41
In-vivo measurement of glucose and alanine metabolism with stable isotopic tracers. Diabetes (1977) 1.41
Seasonality in clinical onset of type 1 diabetes in belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence. Diabetologia (2004) 1.40
Effect of glucocorticoids on plasma insulin. N Engl J Med (1966) 1.39
Cyclic AMP and adrenergic receptor control of rat liver glycogen metabolism. Endocrinology (1972) 1.37
Epidermal growth factor-induced centrosomal separation: mechanism and relationship to mitogenesis. J Cell Biol (1982) 1.35
A new assay for adenosine 3',5'-cyclic monophosphate in tissue. Biochemistry (1967) 1.35
The stimulus-secretion coupling of glucose-induced insulin release. XIV. Glucose regulation of insular biosynthetic activity. Endocrinology (1973) 1.33
Hypoalaninemia: a concomitant of ketotic hypoglycemia. J Clin Invest (1972) 1.33
Alanine and glutamine synthesis and release from skeletal muscle. IV. beta-Adrenergic inhibition of amino acid release. J Biol Chem (1976) 1.33
Determinants of the selective toxicity of alloxan to the pancreatic B cell. Proc Natl Acad Sci U S A (1982) 1.32
Epitrochlearis muscle. I. Mechanical performance, energetics, and fiber composition. Am J Physiol (1980) 1.32
A microfluorometric enzymatic assay for the determination of alanine and pyruvate in plasma and tissues. J Lab Clin Med (1972) 1.32
Juvenile diabetes mellitus, a deficiency in insulin. Diabetes (1968) 1.31
Microtubule-associated proteins of HeLa cells: heat stability of the 200,000 mol wt HeLa MAPs and detection of the presence of MAP-2 in HeLa cell extracts and cycled microtubules. J Cell Biol (1982) 1.30
Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology (1997) 1.30
Radioimmunoassay for the measurement of cyclic nucleotides. Adv Cyclic Nucleotide Res (1972) 1.29
Microtubule assembly and the intracellular transport of secretory granules in pancreatic islets. Science (1976) 1.28
Hypoglycemia in infancy and childhood. II. J Pediatr (1973) 1.28
Insulin-stimulated diacylglycerol production results from the hydrolysis of a novel phosphatidylinositol glycan. J Biol Chem (1987) 1.26
Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation. J Clin Invest (1996) 1.25
Epidermal growth factor induces rapid centrosomal separation in HeLa and 3T3 cells. J Cell Biol (1982) 1.25
Hypoglycemia in infancy and childhood. I. J Pediatr (1973) 1.24
Rapid deposition of amyloid in human islets transplanted into nude mice. Diabetologia (1995) 1.23
Muscle actin filaments bind pituitary secretory granules in vitro. J Cell Biol (1977) 1.21
Evidence for the presence of type I insulin-like growth factor receptors on rat pancreatic A and B cells. Endocrinology (1987) 1.20
Alanine and glutamine synthesis and release from skeletal muscle. III. Dietary and hormonal regulation. J Biol Chem (1976) 1.19
Pancreatic beta cell heterogeneity in glucose-induced insulin secretion. J Biol Chem (1992) 1.19
Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro. Endocrinology (1996) 1.16
D-chiro-inositol metabolism in diabetes mellitus. Proc Natl Acad Sci U S A (1993) 1.15
Correlative studies of growth hormone and insulin plasma concentrations with metabolic abnormalities in acromegaly. J Lab Clin Med (1965) 1.15
Cytokeratins as markers of ductal cell differentiation and islet neogenesis in the neonatal rat pancreas. Diabetes (1994) 1.15
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Effect of diet composition on the hyperinsulinemia of obesity. N Engl J Med (1971) 1.14
Uncontrolled diabetes mellitus and hyperglucagonemia associated with an islet cell carcinoma. Am J Med (1975) 1.14
Differences in adrenergic recognition by pancreatic A and B cells. Science (1986) 1.14
Brain-specific expression of MAP2 detected using a cloned cDNA probe. J Cell Biol (1986) 1.14
Differences in glucose handling by pancreatic A- and B-cells. J Biol Chem (1984) 1.13
Regulation of adenosine 3',5'-monophosphate levels in the pancreatic B cell. Endocrinology (1985) 1.12
Myosins of secretory tissues. J Cell Biol (1978) 1.12
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Insulin and glucagon secretion from rat islets maintained in a tissue culture-perifusion system. Diabetes (1979) 1.07
Effects of glucose and glucagon on the fructose 2,6-bisphosphate content of pancreatic islets and purified pancreatic B-cells. A comparison with isolated hepatocytes. Biochem J (1984) 1.07
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Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes. Diabetologia (2005) 1.04
Binding of colchicine to purified microtubule protein. J Biol Chem (1975) 1.04
Nitric oxide donors decrease the function and survival of human pancreatic islets. Mol Cell Endocrinol (1996) 1.04
Physiological regulation of total tubulin and polymerized tubulin in tissues. J Cell Biol (1977) 1.03
Glutamine and glutamate metabolism in normal and diabetic subjects. Diabetes (1973) 1.02
Selective uptake of alloxan by pancreatic B-cells. Biochem J (1982) 1.02
Effect of short-chain fatty acids on plasma insulin in ruminant and nonruminant species. Endocrinology (1968) 1.02
Associations of GAD65- and IA-2- autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. The Belgian Diabetes Registry. Diabetes Care (1997) 1.02
Sensitivity of rat pancreatic A and B cells to somatostatin. Diabetologia (1989) 1.02