Published in EMBO J on October 01, 1996
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature (2011) 6.31
The many roles of FAS receptor signaling in the immune system. Immunity (2009) 4.67
Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases. EMBO J (2011) 3.06
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J (1998) 2.82
Proteases for cell suicide: functions and regulation of caspases. Microbiol Mol Biol Rev (2000) 2.48
RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol Cell (2011) 2.06
Interdimer processing mechanism of procaspase-8 activation. EMBO J (2003) 2.03
Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF. EMBO J (1999) 1.59
Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway. Mol Cell Biol (1998) 1.59
Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia. Proc Natl Acad Sci U S A (1999) 1.56
The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes. Mol Cell Biol (2002) 1.36
Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein. J Exp Med (1999) 1.31
Dynamics of suppressor T cells: in vivo veritas. J Exp Med (2003) 1.20
T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection. EMBO J (1997) 1.18
Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling. Proc Natl Acad Sci U S A (2004) 1.17
Ripped to death. Trends Cell Biol (2011) 1.14
FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells. Blood (2005) 1.12
TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis. EMBO J (2012) 1.11
Programmed cell death of dendritic cells in immune regulation. Immunol Rev (2010) 1.10
Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors. EMBO J (1999) 1.06
Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection. J Virol (2010) 1.04
Caspases leave the beaten track: caspase-mediated activation of NF-kappaB. J Cell Biol (2006) 1.04
Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor. EMBO J (1999) 1.01
The "fuzzy logic" of the death-inducing signaling complex in lymphocytes. J Clin Immunol (2003) 0.96
Normal thymocyte negative selection in TRAIL-deficient mice. J Exp Med (2003) 0.94
A portrait of the Bcl-2 protein family: life, death, and the whole picture. J Clin Immunol (1999) 0.90
Cell death throes. Proc Natl Acad Sci U S A (1998) 0.81
Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells. Cancer Gene Ther (2008) 0.76
On How Fas Apoptosis-Independent Pathways Drive T Cell Hyperproliferation and Lymphadenopathy in lpr Mice. Front Immunol (2017) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods (1991) 16.64
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature (1995) 15.07
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature (1988) 14.66
The Fas death factor. Science (1995) 13.81
SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol Cell Biol (1988) 12.84
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science (1995) 11.38
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell (1993) 10.35
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell (1995) 9.81
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell (1995) 9.22
bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell (1991) 8.27
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95) Nature (1995) 8.23
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell (1991) 8.13
Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science (1989) 7.76
Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature (1995) 7.52
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell (1994) 7.23
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell (1993) 7.16
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med (1989) 7.07
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol (1991) 6.89
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature (1995) 6.85
Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature (1994) 5.58
Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme. Cell (1992) 5.54
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem (1994) 5.51
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. J Biol Chem (1995) 5.34
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J (1995) 4.68
Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity. J Exp Med (1993) 4.53
The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature (1988) 4.43
Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med (1995) 4.34
Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature (1995) 4.20
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. Genes Dev (1994) 4.19
Prevention of vertebrate neuronal death by the crmA gene. Science (1994) 4.09
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18). Nature (1991) 4.06
T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens. Nature (1988) 4.04
Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases. J Biol Chem (1996) 3.97
Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product. J Biol Chem (1995) 3.83
An evolutionary perspective on apoptosis. Cell (1994) 3.77
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature (1995) 3.59
Fas transduces activation signals in normal human T lymphocytes. J Exp Med (1993) 3.04
Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci U S A (1993) 2.79
Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res (1995) 2.56
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science (1992) 2.54
Effect of bcl-2 on Fas antigen-mediated cell death. J Immunol (1993) 2.50
ICE-like proteases in apoptosis. Trends Biochem Sci (1995) 2.48
The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses. Eur J Immunol (1995) 2.47
Bcl-2 protects from lethal hepatic apoptosis induced by an anti-Fas antibody in mice. Nat Med (1996) 2.26
Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases. J Biol Chem (1995) 2.02
Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A. J Biol Chem (1995) 1.88
Bcl-x and Bcl-2 inhibit TNF and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells. Oncogene (1995) 1.87
Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice. Curr Top Microbiol Immunol (1990) 1.86
Hemorrhage in lesions caused by cowpox virus is induced by a viral protein that is related to plasma protein inhibitors of serine proteases. Proc Natl Acad Sci U S A (1986) 1.85
Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway. Proc Natl Acad Sci U S A (1995) 1.81
CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis. J Biol Chem (1995) 1.53
Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in a T cell hybridoma. J Immunol (1995) 1.50
A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection. J Exp Med (1996) 1.46
FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen. Proc Natl Acad Sci U S A (1995) 1.42
Apoptosis, Fas and systemic autoimmunity: the MRL-lpr/lpr model. Curr Opin Immunol (1994) 1.40
Enhanced and accelerated lymphoproliferation in Fas-null mice. Proc Natl Acad Sci U S A (1996) 1.40
Perforin and granzymes: crucial effector molecules in cytolytic T lymphocyte and natural killer cell-mediated cytotoxicity. Curr Top Microbiol Immunol (1995) 1.22
Regulation of apoptosis and T cell activation by Fas-specific mAb. Int Immunol (1994) 1.22
Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice. Proc Natl Acad Sci U S A (1994) 1.15
The APO-1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice. Eur J Immunol (1994) 1.12
scl, a gene frequently activated in human T cell leukaemia, does not induce lymphomas in transgenic mice. Oncogene (1995) 1.09
Sensitivity of T cells to anti-CD3-stimulated suicide is independent of functional phenotype. Eur J Immunol (1992) 1.02
Deletion analysis of the human CD2 gene locus control region in transgenic mice. Nucleic Acids Res (1991) 0.97
Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice. J Immunol (1995) 0.97
The role of B cell abnormalities in the systemic autoimmune syndromes of lpr and gld mice. Semin Immunol (1994) 0.96
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science (1999) 11.96
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell (2000) 8.69
Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J (1998) 7.17
BH3-Only proteins-essential initiators of apoptotic cell death. Cell (2000) 7.04
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell (1999) 5.92
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev (1995) 5.51
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc Natl Acad Sci U S A (1991) 4.72
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ (2002) 4.64
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science (2001) 4.29
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr Biol (2000) 4.27
An evolutionary perspective on apoptosis. Cell (1994) 3.77
The molecular biology of apoptosis. Proc Natl Acad Sci U S A (1996) 3.39
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc Natl Acad Sci U S A (1996) 3.16
Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice. Cell (1997) 3.13
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron (2001) 3.07
Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim. Dev Cell (2001) 3.03
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J (1998) 2.82
The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry. EMBO J (1996) 2.71
Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death. Oncogene (1997) 2.70
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death Differ (2011) 2.66
RIPK1 is not essential for TNFR1-induced activation of NF-kappaB. Cell Death Differ (2009) 2.59
The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells. Am J Pathol (2000) 2.53
The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry. EMBO J (1997) 2.44
Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Cell Death Differ (2008) 2.36
Fas ligand, Bcl-2, granulocyte colony-stimulating factor, and p38 mitogen-activated protein kinase: Regulators of distinct cell death and survival pathways in granulocytes. J Exp Med (2000) 2.07
Caspase inhibitors. Cell Death Differ (1999) 2.02
Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts. Proc Natl Acad Sci U S A (1997) 2.02
B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J Exp Med (1998) 2.00
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). Proc Natl Acad Sci U S A (1999) 1.99
The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the outer mitochondrial membrane. Cell Growth Differ (1994) 1.98
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line. EMBO J (1992) 1.90
Mutations in the p53 and SCID genes cooperate in tumorigenesis. Genes Dev (1996) 1.89
Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice. Curr Top Microbiol Immunol (1990) 1.86
Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death Differ (2002) 1.85
How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? Cell Death Differ (2007) 1.84
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ (2008) 1.81
Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes. Cell Death Differ (2004) 1.81
Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor. Proc Natl Acad Sci U S A (1996) 1.79
The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression. EMBO J (2000) 1.79
Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs. Genome Biol (2001) 1.78
Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division. Proc Natl Acad Sci U S A (1999) 1.77
bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells. J Exp Med (2000) 1.76
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis. Cell Death Differ (2009) 1.75
Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat. Nat Struct Biol (1999) 1.73
Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes. J Exp Med (1993) 1.73
Fas death receptor signalling: roles of Bid and XIAP. Cell Death Differ (2011) 1.63
Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell Death Differ (2008) 1.60
Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF. EMBO J (1999) 1.59
Proliferation and differentiation of single hapten-specific B lymphocytes is promoted by T-cell factor(s) distinct from T-cell growth factor. Proc Natl Acad Sci U S A (1982) 1.53
Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L). J Cell Biol (2000) 1.50
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy. Biochim Biophys Acta (1997) 1.49
Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors. Blood (2000) 1.46
TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1. Cell Death Dis (2013) 1.46
Caspase inhibitors: viral, cellular and chemical. Cell Death Differ (2006) 1.45
Expression of the integrin alpha 4 beta 1 on melanoma cells can inhibit the invasive stage of metastasis formation. Cell (1994) 1.45
Functional characterization of the Bcl-2 gene family in the zebrafish. Cell Death Differ (2006) 1.43
Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP. EMBO J (2001) 1.43
Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells. J Exp Med (1997) 1.41
Intracellular localization of the BCL-2 family member BOK and functional implications. Cell Death Differ (2013) 1.40
FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor. EMBO J (2000) 1.38
Association of OPRM1 A118G variant with the relative reinforcing value of nicotine. Psychopharmacology (Berl) (2006) 1.37
DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9. J Cell Biol (2001) 1.36
Insights from Bcl-2 and Myc: malignancy involves abrogation of apoptosis as well as sustained proliferation. Cancer Res (1999) 1.35
BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice. Cell Death Differ (2012) 1.35
Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts. Trends Biochem Sci (1998) 1.35
Overexpression of Bcl-2 does not rescue impaired B lymphopoiesis in IL-7 receptor-deficient mice but can enhance survival of mature B cells. Int Immunol (1998) 1.32
Entamoeba histolytica: target cells killed by trophozoites undergo DNA fragmentation which is not blocked by Bcl-2. Exp Parasitol (1994) 1.27
Polycystic kidney disease prevented by transgenic RNA interference. Cell Death Differ (2005) 1.26
Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes. J Immunol (1997) 1.25
Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector. Oncogene (1999) 1.24
Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci. J Exp Med (1993) 1.22
Tissue expression and subcellular localization of the pro-survival molecule Bcl-w. Cell Death Differ (2001) 1.22
Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway. Oncogene (2006) 1.21
Inhibition of interleukin 1 beta-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP. Proc Natl Acad Sci U S A (1996) 1.19
Two kinds of BIR-containing protein - inhibitors of apoptosis, or required for mitosis. J Cell Sci (2001) 1.18
Novel murine homeo box gene on chromosome 1 expressed in specific hematopoietic lineages and during embryogenesis. Genes Dev (1991) 1.18
Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs. Cell Death Differ (2006) 1.17
Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy. J Exp Med (2000) 1.16
Cell death regulation by the mammalian IAP antagonist Diablo/Smac. Apoptosis (2002) 1.15
Is Apaf-1 expression frequently abrogated in melanoma? Cell Death Differ (2005) 1.15
Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation. Cell Death Differ (2005) 1.15
Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection. Eur J Immunol (1998) 1.14
Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1. Cell Death Differ (1999) 1.13
Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo. J Immunol (1997) 1.11
Selective up-regulation of macrophage function in granulocyte-macrophage colony-stimulating factor transgenic mice. J Immunol (1991) 1.11
Antibody production by single, hapten-specific B lymphocytes: an antigen-driven cloning system free of filler or accessory cells. Proc Natl Acad Sci U S A (1981) 1.10
XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland. Cell Death Differ (2005) 1.09
scl, a gene frequently activated in human T cell leukaemia, does not induce lymphomas in transgenic mice. Oncogene (1995) 1.09
Mechanisms of beta cell death in diabetes: a minor role for CD95. Proc Natl Acad Sci U S A (1998) 1.09
Fas ligand-induced c-Jun kinase activation in lymphoid cells requires extensive receptor aggregation but is independent of DAXX, and Fas-mediated cell death does not involve DAXX, RIP, or RAIDD. J Immunol (2000) 1.08
Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia. Cell Death Differ (2007) 1.08
Retracted Immunology. Ways around rejection. Nature (1995) 1.07
Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors. EMBO J (1999) 1.06
Effects of a dominant interfering mutant of FADD on signal transduction in activated T cells. Curr Biol (2001) 1.06
Apoptosis. Death of a T cell. Nature (1995) 1.06
bcl-2 transgene expression promotes survival and reduces proliferation of CD3-CD4-CD8- T cell progenitors. Int Immunol (1997) 1.05