Regulation of product chain length by isoprenyl diphosphate synthases.

PubWeight™: 2.13‹?› | Rank: Top 2%

🔗 View Article (PMC 26348)

Published in Proc Natl Acad Sci U S A on December 24, 1996

Authors

L C Tarshis1, P J Proteau, B A Kellogg, J C Sacchettini, C D Poulter

Author Affiliations

1: Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Articles citing this

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc Natl Acad Sci U S A (2006) 2.73

Diversifying carotenoid biosynthetic pathways by directed evolution. Microbiol Mol Biol Rev (2005) 2.28

Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade. Proc Natl Acad Sci U S A (2001) 2.22

Unearthing the roots of the terpenome. Curr Opin Chem Biol (2008) 2.00

Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene. J Bacteriol (1999) 1.63

Geranyl diphosphate synthase: cloning, expression, and characterization of this prenyltransferase as a heterodimer. Proc Natl Acad Sci U S A (1999) 1.61

A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin. EMBO J (2004) 1.60

Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase. Proc Natl Acad Sci U S A (2001) 1.60

Diterpene cyclases and the nature of the isoprene fold. Proteins (2010) 1.41

Terpenoid synthase structures: a so far incomplete view of complex catalysis. Nat Prod Rep (2012) 1.39

Terpene Specialized Metabolism in Arabidopsis thaliana. Arabidopsis Book (2011) 1.30

Chemistry of the retinoid (visual) cycle. Chem Rev (2013) 1.28

Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2. Am J Physiol Renal Physiol (2008) 1.22

Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis. Curr Opin Chem Biol (2012) 1.15

Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc Natl Acad Sci U S A (2013) 1.06

Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. J Biol Chem (2010) 1.03

Mechanistic aspects of carotenoid biosynthesis. Chem Rev (2013) 1.02

Evolution of the C30 carotenoid synthase CrtM for function in a C40 pathway. J Bacteriol (2002) 1.00

A bifunctional geranyl and geranylgeranyl diphosphate synthase is involved in terpene oleoresin formation in Picea abies. Plant Physiol (2009) 0.99

Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. J Am Chem Soc (2006) 0.99

Isolation and functional expression of an animal geranyl diphosphate synthase and its role in bark beetle pheromone biosynthesis. Proc Natl Acad Sci U S A (2005) 0.96

Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. Plant Cell (2010) 0.96

Metal ions control product specificity of isoprenyl diphosphate synthases in the insect terpenoid pathway. Proc Natl Acad Sci U S A (2013) 0.93

Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorg Med Chem (2007) 0.93

Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. Proteins (2008) 0.92

Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity. Plant Physiol (2006) 0.92

Cloning of the sdsA gene encoding solanesyl diphosphate synthase from Rhodobacter capsulatus and its functional expression in Escherichia coli and Saccharomyces cerevisiae. J Bacteriol (1997) 0.92

Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis. ACS Med Chem Lett (2013) 0.91

Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase. Plant Physiol (2011) 0.91

Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase. Biochem J (2003) 0.89

Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures. J Bacteriol (2005) 0.89

Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorg Med Chem (2011) 0.88

Bioorganic chemistry. A natural reunion of the physical and life sciences. J Org Chem (2009) 0.87

Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase. Biochem J (2005) 0.86

Human isoprenoid synthase enzymes as therapeutic targets. Front Chem (2014) 0.86

The branch point enzyme of the mevalonate pathway for protein prenylation is overexpressed in the ob/ob mouse and induced by adipogenesis. Mol Cell Biol (2000) 0.85

Use B-factor related features for accurate classification between protein binding interfaces and crystal packing contacts. BMC Bioinformatics (2014) 0.84

Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J Med Chem (2012) 0.84

Frequencies of hydrophobic and hydrophilic runs and alternations in proteins of known structure. Protein Sci (2006) 0.84

1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase. Org Biomol Chem (2012) 0.84

Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. Appl Environ Microbiol (2005) 0.84

Determination of residues responsible for substrate and product specificity of Solanum habrochaites short-chain cis-prenyltransferases. Plant Physiol (2013) 0.83

Novel medium-chain prenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus solfataricus. J Bacteriol (2002) 0.83

Crystal structure of heterodimeric hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26 reveals that the small subunit is directly involved in the product chain length regulation. J Biol Chem (2010) 0.81

Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. BMC Struct Biol (2012) 0.81

Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallogr D Biol Crystallogr (2014) 0.80

Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase. J Org Chem (2011) 0.80

Functional analysis of (4S)-limonene synthase mutants reveals determinants of catalytic outcome in a model monoterpene synthase. Proc Natl Acad Sci U S A (2015) 0.80

The N-terminus and the chain-length determination domain play a role in the length of the isoprenoid product of the bifunctional Toxoplasma gondii farnesyl diphosphate synthase. Biochemistry (2012) 0.80

Structural characterization of substrate and inhibitor binding to farnesyl pyrophosphate synthase from Pseudomonas aeruginosa. Acta Crystallogr D Biol Crystallogr (2015) 0.78

A corpora allata farnesyl diphosphate synthase in mosquitoes displaying a metal ion dependent substrate specificity. Insect Biochem Mol Biol (2015) 0.78

Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver. Planta (2012) 0.78

Adaptive evolution of the chrysanthemyl diphosphate synthase gene involved in irregular monoterpene metabolism. BMC Evol Biol (2012) 0.78

Identification of the Final Two Genes Functioning in Methanofuran Biosynthesis in Methanocaldococcus jannaschii. J Bacteriol (2015) 0.78

A high-throughput colorimetric screening assay for terpene synthase activity based on substrate consumption. PLoS One (2014) 0.77

Mechanistic insights into protonation state as a critical factor in hFPPS enzyme inhibition. J Comput Aided Mol Des (2015) 0.76

Human farnesyl pyrophosphate synthase inhibition by nitrogen bisphosphonates: a 3D-QSAR study. J Comput Aided Mol Des (2013) 0.76

Overexpression of a synthetic insect-plant geranyl pyrophosphate synthase gene in Camelina sativa alters plant growth and terpene biosynthesis. Planta (2016) 0.76

Cloning and characterization of farnesyl diphosphate synthase gene involved in triterpenoids biosynthesis from Poria cocos. Int J Mol Sci (2014) 0.76

Cloning and characterization of farnesyl pyrophosphate synthase from the highly branched isoprenoid producing diatom Rhizosolenia setigera. Sci Rep (2015) 0.75

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. Proteins (2014) 0.75

Mutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites. J Biol Chem (2014) 0.75

Molecular characterization of farnesyl pyrophosphate synthase from Bacopa monniera by comparative modeling and docking studies. Bioinformation (2012) 0.75

Structural and Chemical Biology of Terpenoid Cyclases. Chem Rev (2017) 0.75

Articles cited by this

Basic local alignment search tool. J Mol Biol (1990) 659.07

Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol (1987) 66.52

Crystallographic R factor refinement by molecular dynamics. Science (1987) 15.90

Diffraction methods for biological macromolecules. Interactive computer graphics: FRODO. Methods Enzymol (1985) 6.64

Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution. Biochemistry (1994) 3.10

Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase. J Biol Chem (1990) 2.19

Studies on the biosynthesis of cholesterol. XX. Steric course of decarboxylation of 5-pyrophosphomevalonate and of the carbon to carbon bond formation in the biosynthesis of farnesyl pyrophosphate. J Biol Chem (1966) 2.08

Isoprenyl diphosphate synthases: protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure. Protein Sci (1994) 1.82

Yeast farnesyl-diphosphate synthase: site-directed mutagenesis of residues in highly conserved prenyltransferase domains I and II. Proc Natl Acad Sci U S A (1994) 1.69

Efficient enzymatic hydrolysis of polyprenyl pyrophosphates. Biochim Biophys Acta (1982) 1.65

Farnesyl diphosphate synthetase. Molecular cloning, sequence, and expression of an essential gene from Saccharomyces cerevisiae. J Biol Chem (1989) 1.48

BTS1 encodes a geranylgeranyl diphosphate synthase in Saccharomyces cerevisiae. J Biol Chem (1995) 1.15

Prenyltransferase; determination of the binding mechanism and individual kinetic constants for farnesylpyrophosphate synthetase by rapid quench and isotope partitioning experiments. Biochemistry (1981) 1.14

Characterization of a lysine-to-glutamic acid mutation in a conservative sequence of farnesyl diphosphate synthase from Saccharomyces cerevisiae. Gene (1993) 1.09

Conversion from farnesyl diphosphate synthase to geranylgeranyl diphosphate synthase by random chemical mutagenesis. J Biol Chem (1996) 1.06

Analysis and purification of phosphorylated isoprenoids by reversed-phase HPLC. Anal Biochem (1993) 1.03

Substrate Binding of avian liver prenyltransferase. Biochemistry (1976) 1.03

Crystallization and partial characterization of prenyltransferase from avian liver. Biochemistry (1975) 1.02

Purification of solanesyl-diphosphate synthase from Micrococcus luteus. A new class of prenyltransferase. J Biol Chem (1991) 0.92

Purification of farnesylpyrophosphate synthetase by affinity chromatography. Methods Enzymol (1985) 0.90

Avian liver prenyltransferase. The role of metal in substrate binding and the orientation of substrates during catalysis. Biochemistry (1977) 0.86

Articles by these authors

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature (2000) 11.48

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis. Science (1998) 4.08

Creating isoprenoid diversity. Science (1997) 3.78

Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. J Pharmacol Exp Ther (2001) 3.59

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis. Science (1995) 3.25

Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution. Biochemistry (1994) 3.10

Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis. Biochemistry (1995) 3.04

Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing. Nat Struct Biol (1998) 2.59

Rational design of potent human transthyretin amyloid disease inhibitors. Nat Struct Biol (2000) 2.57

Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines. Nat Struct Biol (2000) 2.24

Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nat Genet (2000) 2.19

Synthesis of allylic and homoallylic isoprenoid pyrophosphates. Methods Enzymol (1985) 2.18

Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc Natl Acad Sci U S A (1992) 2.16

Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the ras protein. Science (1990) 2.04

Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis. J Bacteriol (2000) 1.94

Crystal structure of a plant catechol oxidase containing a dicopper center. Nat Struct Biol (1998) 1.93

The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection. Cell (1994) 1.90

Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nat Struct Biol (2000) 1.87

An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured. Biochemistry (2001) 1.85

Isoprenyl diphosphate synthases: protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure. Protein Sci (1994) 1.82

Chain elongation in the isoprenoid biosynthetic pathway. Curr Opin Chem Biol (1997) 1.78

Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J (1998) 1.74

Yeast farnesyl-diphosphate synthase: site-directed mutagenesis of residues in highly conserved prenyltransferase domains I and II. Proc Natl Acad Sci U S A (1994) 1.69

Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase. J Bacteriol (1999) 1.64

Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate. J Biol Chem (1999) 1.59

Expression of rat intestinal fatty acid-binding protein in Escherichia coli. Purification and comparison of ligand binding characteristics with that of Escherichia coli-derived rat liver fatty acid-binding protein. J Biol Chem (1987) 1.58

Isopentenyl diphosphate:dimethylallyl diphosphate isomerase. An improved purification of the enzyme and isolation of the gene from Saccharomyces cerevisiae. J Biol Chem (1989) 1.56

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinb) (2003) 1.55

Refinement of the structure of recombinant rat intestinal fatty acid-binding apoprotein at 1.2-A resolution. J Biol Chem (1992) 1.54

An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance. J Clin Invest (1995) 1.51

The Claviceps purpurea gene encoding dimethylallyltryptophan synthase, the committed step for ergot alkaloid biosynthesis. Biochem Biophys Res Commun (1995) 1.51

Three-dimensional structure of recombinant human muscle fatty acid-binding protein. J Biol Chem (1992) 1.49

Farnesyl diphosphate synthetase. Molecular cloning, sequence, and expression of an essential gene from Saccharomyces cerevisiae. J Biol Chem (1989) 1.48

A general method for facilitating heterodimeric pairing between two proteins: application to expression of alpha and beta T-cell receptor extracellular segments. Proc Natl Acad Sci U S A (1994) 1.44

The crtE gene in Erwinia herbicola encodes geranylgeranyl diphosphate synthase. Proc Natl Acad Sci U S A (1992) 1.42

Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi. J Biol Chem (2001) 1.42

Determining protein structure from electron-density maps using pattern matching. Acta Crystallogr D Biol Crystallogr (2000) 1.38

Crystal structure of orotate phosphoribosyltransferase. Biochemistry (1994) 1.38

Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein. J Biol Chem (2000) 1.38

1H-15N NMR studies of Escherichia coli tRNA(Phe) from hisT mutants: a structural role for pseudouridine. Biochemistry (1991) 1.38

The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP. Cell (1994) 1.37

Effects of site-directed mutagenesis of the highly conserved aspartate residues in domain II of farnesyl diphosphate synthase activity. J Biol Chem (1992) 1.35

Inhibiting transthyretin conformational changes that lead to amyloid fibril formation. Proc Natl Acad Sci U S A (1998) 1.35

Structural evidence for a pH-sensitive dilysine trigger in the hen ovotransferrin N-lobe: implications for transferrin iron release. Biochemistry (1993) 1.34

Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target. Structure (1998) 1.32

E. coli MEP synthase: steady-state kinetic analysis and substrate binding. Biochemistry (2002) 1.32

Isopentenyl-diphosphate isomerase: inactivation of the enzyme with active-site-directed irreversible inhibitors and transition-state analogues. Biochemistry (1988) 1.32

Structural studies on human muscle fatty acid binding protein at 1.4 A resolution: binding interactions with three C18 fatty acids. Structure (1994) 1.29

Continuous fluorescence assay for protein prenyltransferases. Methods Enzymol (1995) 1.27

The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance. Microbiology (1998) 1.27

15N-labeled Escherichia coli tRNAfMet, tRNAGlu, tRNATyr, and tRNAPhe. Double resonance and two-dimensional NMR of N1-labeled pseudouridine. J Biol Chem (1985) 1.27

The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities. Mol Cell Biol (2000) 1.22

Fatty acid interactions with rat intestinal and liver fatty acid-binding proteins expressed in Escherichia coli. A comparative 13C NMR study. J Biol Chem (1989) 1.22

Pre-steady-state study of recombinant sesquiterpene cyclases. Biochemistry (1997) 1.22

1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. J Bacteriol (2001) 1.19

Studies with recombinant Saccharomyces cerevisiae CaaX prenyl protease Rce1p. Biochemistry (2000) 1.18

Structure of malhamensilipin A, an inhibitor of protein tyrosine kinase, from the cultured chrysophyte Poterioochromonas malhamensis. J Nat Prod (1994) 1.18

A mechanism for posttranslational modifications of proteins by yeast protein farnesyltransferase. Proc Natl Acad Sci U S A (1995) 1.18

Isopentenyldiphosphate:dimethylallyldiphosphate isomerase: construction of a high-level heterologous expression system for the gene from Saccharomyces cerevisiae and identification of an active-site nucleophile. Biochemistry (1990) 1.17

A new function for a common fold: the crystal structure of quinolinic acid phosphoribosyltransferase. Structure (1997) 1.14

Purification and characterization of farnesyl diphosphate/geranylgeranyl diphosphate synthase. A thermostable bifunctional enzyme from Methanobacterium thermoautotrophicum. J Biol Chem (1993) 1.14

Prenyltransferase; determination of the binding mechanism and individual kinetic constants for farnesylpyrophosphate synthetase by rapid quench and isotope partitioning experiments. Biochemistry (1981) 1.14

The gelatinolytic activity of rat uterus collagenase. J Biol Chem (1985) 1.13

Identification of Cys139 and Glu207 as catalytically important groups in the active site of isopentenyl diphosphate:dimethylallyl diphosphate isomerase. Biochemistry (1994) 1.13

Isolation and characterization of isoprene mutants of Escherichia coli. J Bacteriol (1989) 1.13

The 2.0-A resolution structure of soybean beta-amylase complexed with alpha-cyclodextrin. Biochemistry (1993) 1.12

Farnesyl pyrophosphate synthetase. Mechanistic studies of the 1'-4 coupling reaction with 2-fluorogeranyl pyrophosphate. J Biol Chem (1978) 1.11

X-ray crystal structure of the soybean agglutinin cross-linked with a biantennary analog of the blood group I carbohydrate antigen. Biochemistry (1995) 1.10

Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase. Biochemistry (1995) 1.09

Open reading frame 176 in the photosynthesis gene cluster of Rhodobacter capsulatus encodes idi, a gene for isopentenyl diphosphate isomerase. J Bacteriol (1996) 1.08

Yeast squalene synthase: expression, purification, and characterization of soluble recombinant enzyme. Arch Biochem Biophys (1993) 1.08

The three-dimensional structures of a polysaccharide binding antibody to Cryptococcus neoformans and its complex with a peptide from a phage display library: implications for the identification of peptide mimotopes. J Mol Biol (1997) 1.07

Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein. Structure (1996) 1.07

Chrysanthemyl diphosphate synthase: isolation of the gene and characterization of the recombinant non-head-to-tail monoterpene synthase from Chrysanthemum cinerariaefolium. Proc Natl Acad Sci U S A (2001) 1.06

Inosine-uridine nucleoside hydrolase from Crithidia fasciculata. Genetic characterization, crystallization, and identification of histidine 241 as a catalytic site residue. Biochemistry (1996) 1.05

Analysis of the isopentenyl diphosphate isomerase gene family from Arabidopsis thaliana. Plant Mol Biol (1998) 1.04

The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and alpha-D-5-phosphoribosyl-1-pyrophosphate. Biochemistry (1995) 1.04

Rat heart fatty acid-binding protein is highly homologous to the murine adipocyte 422 protein and the P2 protein of peripheral nerve myelin. J Biol Chem (1986) 1.04

Purification and characterization of dimethylallyl tryptophan synthase from Claviceps purpurea. Arch Biochem Biophys (1992) 1.03

Analysis and purification of phosphorylated isoprenoids by reversed-phase HPLC. Anal Biochem (1993) 1.03

Multiple quantum two-dimensional 1H--15N nuclear magnetic resonance spectroscopy: chemical shift correlation maps for exchangeable imino protons of Escherichia coli tRNAMetf in water. Proc Natl Acad Sci U S A (1983) 1.03

Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization. Arch Biochem Biophys (1996) 1.02

Binding of fatty acids and peroxisome proliferators to orthologous fatty acid binding proteins from human, murine, and bovine liver. Biochemistry (2000) 1.02

Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 A resolution and I-FABPArg106-->Gln with bound oleate at 1.74 A resolution. J Biol Chem (1993) 1.01

Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: essential elements for recognition of tRNA substrates within the anticodon stem-loop. Biochemistry (2000) 1.01

A polymorphism in the human intestinal fatty acid binding protein alters fatty acid transport across Caco-2 cells. J Biol Chem (1996) 1.01

The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide. Proc Natl Acad Sci U S A (1997) 0.99

Synthesis of (S)-isoprenoid thiodiphosphates as substrates and inhibitors. J Org Chem (2001) 0.99

Mechanism of the prenyl-transfer reaction. Studies with (E)- and (Z)-3-trifluoromethyl-2-buten-1-yl pyrophosphate. Biochemistry (1977) 0.98

Crystallization of a deglycosylated T cell receptor (TCR) complexed with an anti-TCR Fab fragment. J Biol Chem (1996) 0.98

Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: site-directed mutagenesis of highly conserved residues. Biochemistry (2001) 0.97

Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit. J Biomol NMR (1997) 0.97

Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry. Biochemistry (1997) 0.97

Protein farnesyltransferase: production in Escherichia coli and immunoaffinity purification of the heterodimer from Saccharomyces cerevisiae. Gene (1993) 0.97

Locations and functional roles of conserved lysine residues in Salmonella typhimurium orotate phosphoribosyltransferase. Biochemistry (1995) 0.96

X-ray crystallographic studies of unique cross-linked lattices between four isomeric biantennary oligosaccharides and soybean agglutinin. Biochemistry (1997) 0.96

Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: a binding mechanism for recombinant enzyme. Biochemistry (1997) 0.96

Disruption and mapping of IDI1, the gene for isopentenyl diphosphate isomerase in Saccharomyces cerevisiae. Yeast (1992) 0.95

Squalene synthase: steady-state, pre-steady-state, and isotope-trapping studies. Biochemistry (2000) 0.95