Published in Proc Natl Acad Sci U S A on May 13, 1997
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The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev (1999) 1.95
HERP, a new primary target of Notch regulated by ligand binding. Mol Cell Biol (2001) 1.85
Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1. Mol Cell Biol (2005) 1.79
HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling. Mol Cell Biol (2001) 1.77
Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms. Proc Natl Acad Sci U S A (2000) 1.73
Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer. Mol Biol Cell (2007) 1.69
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Gut endocrine cell development. Mol Cell Endocrinol (2009) 1.29
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Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells. Br J Cancer (2005) 1.19
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Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesis. Cell Stem Cell (2011) 1.16
p107 regulates neural precursor cells in the mammalian brain. J Cell Biol (2004) 1.15
Identification and validation of Notch pathway activating compounds through a novel high-throughput screening method. Cancer (2010) 1.15
Down-regulation of Notch1 signaling inhibits tumor growth in human hepatocellular carcinoma. Am J Transl Res (2009) 1.04
Valproic acid induces Notch1 signaling in small cell lung cancer cells. J Surg Res (2008) 0.99
Notch signaling proteins: legitimate targets for cancer therapy. Curr Protein Pept Sci (2010) 0.98
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Characterization of differential transcript abundance through time during Nematostella vectensis development. BMC Genomics (2013) 0.98
Activation of Notch signaling pathway in HIV-associated nephropathy. AIDS (2010) 0.97
Pro-neural transcription factors as cancer markers. BMC Med Genomics (2008) 0.97
Mammalian Scratch: a neural-specific Snail family transcriptional repressor. Proc Natl Acad Sci U S A (2001) 0.93
Current perspectives on the use of alternative species in human health and ecological hazard assessments. Environ Health Perspect (2013) 0.92
Expression of the active Notch1 decreases MTC tumor growth in vivo. J Surg Res (2011) 0.91
The homeodomain protein Cux1 interacts with Grg4 to repress p27 kip1 expression during kidney development. Gene (2009) 0.91
Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear. Dev Dyn (2006) 0.91
bHLH-Orange Transcription Factors in Development and Cancer. Transl Oncogenomics (2007) 0.89
Transcriptional regulation of human MAP2 gene in melanoma: role of neuronal bHLH factors and Notch1 signaling. Nucleic Acids Res (2006) 0.87
Eliciting the T cell fate with Notch. Semin Immunol (2010) 0.86
Ascl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells. PLoS One (2011) 0.86
Increased stathmin1 expression in the dentate gyrus of mice causes abnormal axonal arborizations. PLoS One (2010) 0.86
Phorbol-Ester Mediated Suppression of hASH1 Synthesis: Multiple Ways to Keep the Level Down. Front Mol Neurosci (2011) 0.85
Notch in the development of thyroid C-cells and the treatment of medullary thyroid cancer. Am J Transl Res (2010) 0.85
Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons. Development (2013) 0.84
Modelling the Delta1/Notch1 pathway: in search of the mediator(s) of neural stem cell differentiation. PLoS One (2011) 0.84
Notch3 is important for TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer bone metastasis by regulating ZEB-1. Cancer Gene Ther (2014) 0.84
HeyL promotes neuronal differentiation of neural progenitor cells. J Neurosci Res (2011) 0.84
Sodium butyrate activates Notch1 signaling, reduces tumor markers, and induces cell cycle arrest and apoptosis in pheochromocytoma. Am J Transl Res (2009) 0.83
Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferation. Breast Cancer Res (2009) 0.82
E-box motifs within the human vasopressin gene promoter contribute to a major enhancer in small-cell lung cancer. Biochem J (1999) 0.80
Thiocoraline alters neuroendocrine phenotype and activates the Notch pathway in MTC-TT cell line. Cancer Med (2013) 0.80
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Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia. J Biol Chem (2014) 0.78
E-proteins orchestrate the progression of neural stem cell differentiation in the postnatal forebrain. Neural Dev (2014) 0.78
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Choices choices: regulation of precursor differentiation during enteric nervous system development. Neurogastroenterol Motil (2013) 0.75
Toward a better understanding of enteric gliogenesis. Neurogenesis (Austin) (2017) 0.75
Stochastic simulation of notch signaling reveals novel factors that mediate the differentiation of neural stem cells. J Comput Biol (2014) 0.75
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Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors. Nature (1990) 2.60
Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. Genes Dev (1992) 2.59
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Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J (1994) 2.35
Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J Virol (1992) 2.29
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Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system. Mech Dev (1993) 1.79
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The cellular function of MASH1 in autonomic neurogenesis. Neuron (1995) 1.62
A chicken achaete-scute homolog (CASH-1) is expressed in a temporally and spatially discrete manner in the developing nervous system. Development (1994) 1.23
A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation. Mol Cell Biol (1993) 1.18
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Differentiation of medullary thyroid cancer by C-Raf-1 silences expression of the neural transcription factor human achaete-scute homolog-1. Surgery (1996) 1.09
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