Published in EMBO J on May 15, 1997
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev (2000) 7.29
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J (1998) 5.25
Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics (2001) 4.73
The Bloom's syndrome gene product promotes branch migration of holliday junctions. Proc Natl Acad Sci U S A (2000) 4.67
Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev (2001) 3.99
RecQ helicases: suppressors of tumorigenesis and premature aging. Biochem J (2003) 3.71
The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes Dev (2000) 3.40
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1. Mol Cell Biol (2000) 3.27
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J (2007) 3.22
DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J (2003) 3.15
Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc Natl Acad Sci U S A (1998) 3.14
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc Natl Acad Sci U S A (2006) 3.00
RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination. Genes Dev (1998) 2.92
Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance. Mol Cell Biol (1997) 2.76
Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol (2004) 2.55
Bipartite structure of the SGS1 DNA helicase in Saccharomyces cerevisiae. Genetics (2000) 2.55
Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev (2003) 2.53
RecQ helicases: guardian angels of the DNA replication fork. Chromosoma (2008) 2.43
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. Genes Dev (2009) 2.43
Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III. Genes Dev (2002) 2.37
RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J (2005) 2.34
Regulation and localization of the Bloom syndrome protein in response to DNA damage. J Cell Biol (2001) 2.30
Homologous recombination resolution defect in werner syndrome. Mol Cell Biol (2002) 2.21
Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast. Mol Cell Biol (2004) 2.20
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest. Mol Cell Biol (2004) 2.20
Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene. Genes Dev (1998) 2.12
Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase. EMBO J (2000) 2.08
Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers. Mol Cell Biol (2005) 2.06
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.99
Mapping the DNA topoisomerase III binding domain of the Sgs1 DNA helicase. J Biol Chem (2000) 1.96
Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast. Mol Biol Cell (2003) 1.96
Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. EMBO J (2004) 1.94
Nucleolar localization of the Werner syndrome protein in human cells. Proc Natl Acad Sci U S A (1998) 1.92
The essential role of yeast topoisomerase III in meiosis depends on recombination. EMBO J (1999) 1.88
Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases. Mol Cell Biol (1999) 1.83
The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins. Mol Cell Biol (2005) 1.82
Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A. Nucleic Acids Res (1998) 1.80
Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae. Genetics (2002) 1.79
The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells. Mol Biol Cell (1999) 1.73
Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta. Nucleic Acids Res (2000) 1.63
Loss of Werner syndrome protein function promotes aberrant mitotic recombination. Genes Dev (2001) 1.61
Nuclear structure in normal and Bloom syndrome cells. Proc Natl Acad Sci U S A (2000) 1.60
Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle. Mol Biol Cell (2001) 1.55
RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability. Mol Cell Biol (2006) 1.54
Fission yeast rad12+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene. Mol Cell Biol (1998) 1.53
Meiotic recombination and chromosome segregation in Schizosaccharomyces pombe. Proc Natl Acad Sci U S A (2001) 1.50
Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene. Genetics (1999) 1.48
Substrate-specific inhibition of RecQ helicase. Nucleic Acids Res (2001) 1.46
A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair. Genetics (2005) 1.46
Sws1 is a conserved regulator of homologous recombination in eukaryotic cells. EMBO J (2006) 1.46
Sgs1 regulates gene conversion tract lengths and crossovers independently of its helicase activity. Mol Cell Biol (2006) 1.45
Role for the fission yeast RecQ helicase in DNA repair in G2. Mol Cell Biol (2003) 1.45
Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation. Mol Cell Biol (2003) 1.43
Functional interaction between the Werner Syndrome protein and DNA polymerase delta. Proc Natl Acad Sci U S A (2000) 1.42
Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae. Curr Genet (2002) 1.42
Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1. Nucleic Acids Res (2001) 1.41
The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast. Nucleic Acids Res (2004) 1.41
Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage. Mol Cell Biol (2005) 1.40
Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA. Nucleic Acids Res (2000) 1.38
A natural meiotic DNA break site in Schizosaccharomyces pombe is a hotspot of gene conversion, highly associated with crossing over. Genetics (2004) 1.32
Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks. J Cell Biol (2003) 1.32
Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated. Mol Cell Biol (2000) 1.31
Multiple functions of Drosophila BLM helicase in maintenance of genome stability. Genetics (2007) 1.30
The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A. Nucleic Acids Res (2006) 1.28
Mutational effect of fission yeast polalpha on cell cycle events. Mol Biol Cell (1998) 1.26
Nascent DNA processing by RecJ favors lesion repair over translesion synthesis at arrested replication forks in Escherichia coli. Proc Natl Acad Sci U S A (2006) 1.25
RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe. Mol Biol Cell (2007) 1.25
Rhp51-dependent recombination intermediates that do not generate checkpoint signal are accumulated in Schizosaccharomyces pombe rad60 and smc5/6 mutants after release from replication arrest. Mol Cell Biol (2006) 1.25
Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity. Mol Cell Biol (2000) 1.24
SGS1 is a multicopy suppressor of srs2: functional overlap between DNA helicases. Nucleic Acids Res (2002) 1.24
A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway. Proc Natl Acad Sci U S A (2002) 1.23
Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae. Mol Biol Cell (2009) 1.22
mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation. Eukaryot Cell (2002) 1.22
RecQ promotes toxic recombination in cells lacking recombination intermediate-removal proteins. Mol Cell (2007) 1.21
Telomeres: structures in need of unwinding. FEBS Lett (2010) 1.21
Involvement of Schizosaccharomyces pombe Srs2 in cellular responses to DNA damage. Nucleic Acids Res (2001) 1.19
RECQ1 possesses DNA branch migration activity. J Biol Chem (2008) 1.19
RecQ helicases: lessons from model organisms. Nucleic Acids Res (2006) 1.19
Mutator phenotype induced by aberrant replication. Mol Cell Biol (1999) 1.18
Brc1-mediated DNA repair and damage tolerance. Genetics (2005) 1.18
Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line. Mol Cell Biol (2004) 1.16
Checkpoints: it takes more than time to heal some wounds. Curr Biol (2001) 1.16
Bloom's syndrome protein, BLM, colocalizes with replication protein A in meiotic prophase nuclei of mammalian spermatocytes. Proc Natl Acad Sci U S A (1999) 1.16
The absence of Top3 reveals an interaction between the Sgs1 and Pif1 DNA helicases in Saccharomyces cerevisiae. Genetics (2006) 1.15
The adenovirus E1b55K/E4orf6 complex induces degradation of the Bloom helicase during infection. J Virol (2010) 1.15
Hemicatenanes form upon inhibition of DNA replication. Nucleic Acids Res (2000) 1.13
The severe slow growth of Deltasrs2 Deltarqh1 in Schizosaccharomyces pombe is suppressed by loss of recombination and checkpoint genes. Nucleic Acids Res (2002) 1.13
Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast. PLoS Genet (2010) 1.11
Association of yeast DNA topoisomerase III and Sgs1 DNA helicase: studies of fusion proteins. Proc Natl Acad Sci U S A (2001) 1.11
Unique and important consequences of RECQ1 deficiency in mammalian cells. Cell Cycle (2008) 1.09
A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase. Mol Cell Biol (2002) 1.08
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha. Nucleic Acids Res (2002) 1.08
Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonuclease. Mol Biol Cell (2006) 1.05
Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects. Mol Cell Biol (2005) 1.04
The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant. Nucleic Acids Res (2009) 1.03
WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks. Mol Biol Cell (2008) 1.02
Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere loss. Mol Biol Cell (2007) 1.02
Holliday junction-containing DNA structures persist in cells lacking Sgs1 or Top3 following exposure to DNA damage. Proc Natl Acad Sci U S A (2011) 1.02
Sgs1 helicase activity is required for mitotic but apparently not for meiotic functions. Mol Cell Biol (2000) 1.02
The fission yeast Crb2/Chk1 pathway coordinates the DNA damage and spindle checkpoint in response to replication stress induced by topoisomerase I inhibitor. Mol Cell Biol (2005) 1.00
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol (1991) 33.90
Checkpoints: controls that ensure the order of cell cycle events. Science (1989) 21.01
Positional cloning of the Werner's syndrome gene. Science (1996) 10.98
Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res (1989) 10.03
The Bloom's syndrome gene product is homologous to RecQ helicases. Cell (1995) 9.91
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol Cell Biol (1994) 7.31
DNA topoisomerase II is required at the time of mitosis in yeast. Cell (1985) 6.08
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell (1995) 6.00
Creative blocks: cell-cycle checkpoints and feedback controls. Nature (1992) 5.59
DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe. Cell (1987) 5.52
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell (1990) 5.42
Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization. EMBO J (1984) 5.03
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J (1992) 4.98
Bloom syndrome: a mendelian prototype of somatic mutational disease. Medicine (Baltimore) (1993) 4.89
Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev (1992) 4.62
SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics (1996) 4.62
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol Biol Cell (1994) 4.58
The Schizosaccharomyces pombe rad3 checkpoint gene. EMBO J (1996) 4.45
Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell (1995) 4.08
Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe. Gene (1992) 3.86
Mitotic spindle pulls but fails to separate chromosomes in type II DNA topoisomerase mutants: uncoordinated mitosis. EMBO J (1986) 3.53
Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast. J Cell Sci (1990) 3.47
Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis. EMBO J (1986) 3.42
Human homologues of yeast helicase. Nature (1996) 2.71
A fission yeast RCC1-related protein is required for the mitosis to interphase transition. EMBO J (1994) 2.15
Cloning and characterisation of the S. pombe rad15 gene, a homologue to the S. cerevisiae RAD3 and human ERCC2 genes. Nucleic Acids Res (1992) 2.13
Feedback controls and G2 checkpoints: fission yeast as a model system. Bioessays (1993) 2.00
Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM. Trends Biochem Sci (1995) 1.93
Spontaneous and induced chromosomal instability in Werner syndrome. Hum Genet (1988) 1.80
Cell cycle control of replication initiation in eukaryotes. Curr Opin Cell Biol (1996) 1.77
Yeast pip3/mec3 mutants fail to delay entry into S phase and to slow DNA replication in response to DNA damage, and they define a functional link between Mec3 and DNA primase. Mol Cell Biol (1996) 1.61
Spontaneous and UV-induced recombination in radiation-sensitive mutants of Schizosaccharomyces pombe. Mutat Res (1981) 1.41
Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy: do the genes explain the diseases? Trends Genet (1996) 1.31
DNA mismatch repair and cancer. Gastroenterology (1995) 1.25
Nucleotide excision repair syndromes: molecular basis and clinical symptoms. Philos Trans R Soc Lond B Biol Sci (1995) 1.21
Chromatid exchanges in ataxia telangiectasia, Bloom syndrome, Werner syndrome, and xeroderma pigmentosum. Ann Hum Genet (1976) 1.21
5-Bromodeoxyuridine-dependent increase in sister chromatid exchange formation in Bloom's syndrome is associated with reduction in topoisomerase II activity. Exp Cell Res (1987) 1.14
Mitotic checkpoint control in fission yeast. Cold Spring Harb Symp Quant Biol (1991) 1.11
The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer. Trends Genet (1995) 0.99
Hypersensitivity of Bloom's syndrome fibroblasts to N-ethyl-N-nitrosourea. Mutat Res (1987) 0.99
The G1/S cell-cycle checkpoint in eukaryotic cells. Biochim Biophys Acta (1994) 0.98
Sister chromatid exchange frequencies in Progeria and Werner syndrome patients. Am J Hum Genet (1981) 0.96
A large circular minichromosome of Schizosaccharomyces pombe requires a high dose of type II DNA topoisomerase for its stabilization. Mol Gen Genet (1995) 0.95
Hydroxyurea treatment does not prevent initiation of DNA synthesis in Ehrlich ascites tumour cells and leads to the accumulation of short DNA fragments containing the replication origins. Biochim Biophys Acta (1984) 0.92
Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat Cell Biol (2001) 5.05
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J (1992) 4.98
S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes Dev (1998) 4.63
Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev (1992) 4.62
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol Biol Cell (1994) 4.58
The Schizosaccharomyces pombe rad3 checkpoint gene. EMBO J (1996) 4.45
Activation of the human beta-interferon gene requires an interferon-inducible factor. Mol Cell Biol (1986) 4.38
Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe. Gene (1992) 3.86
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Genes Dev (1996) 3.70
Pain measurement: an overview. Pain (1985) 3.54
Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature (1998) 3.36
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr Biol (2000) 3.34
A Rad3-Rad26 complex responds to DNA damage independently of other checkpoint proteins. Nat Cell Biol (1999) 3.05
Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9. Mol Cell Biol (2000) 2.91
Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. Proc Natl Acad Sci U S A (1998) 2.81
Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance. Mol Cell Biol (1997) 2.76
Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins. EMBO J (1995) 2.73
The G2-phase DNA-damage checkpoint. Trends Cell Biol (2000) 2.64
Cloning the RAD51 homologue of Schizosaccharomyces pombe. Nucleic Acids Res (1993) 2.57
The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair. Mol Cell Biol (1995) 2.52
Vectors for the expression of tagged proteins in Schizosaccharomyces pombe. Gene (1998) 2.47
14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast. Science (1994) 2.38
Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses. EMBO J (1998) 2.32
The evolution of diverse biological responses to DNA damage: insights from yeast and p53. Nat Cell Biol (2001) 2.25
Quantification of the close association between DNA haplotypes and specific beta-thalassaemia mutations in Mediterraneans. Nature (1984) 2.18
Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe. EMBO J (2001) 2.15
Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage. Mol Cell Biol (1994) 2.13
Cloning and characterisation of the S. pombe rad15 gene, a homologue to the S. cerevisiae RAD3 and human ERCC2 genes. Nucleic Acids Res (1992) 2.13
Cloning and characterisation of the rad9 DNA repair gene from Schizosaccharomyces pombe. Nucleic Acids Res (1991) 2.12
Feedback controls and G2 checkpoints: fission yeast as a model system. Bioessays (1993) 2.00
Rad18 is required for DNA repair and checkpoint responses in fission yeast. Mol Biol Cell (1999) 1.98
The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis. J Cell Sci (1995) 1.85
Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity. J Cell Sci (1996) 1.84
Fission yeast wee1 protein kinase is not required for DNA damage-dependent mitotic arrest. Nature (1993) 1.81
Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage. EMBO J (1998) 1.74
DNA structure checkpoint pathways in Schizosaccharomyces pombe. Biochimie (1999) 1.73
Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress. Genes Dev (2000) 1.70
Cloning and characterization of the rad4 gene of Schizosaccharomyces pombe; a gene showing short regions of sequence similarity to the human XRCC1 gene. Nucleic Acids Res (1991) 1.66
Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes. Curr Biol (1997) 1.57
Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair. EMBO J (2001) 1.55
The COP9/signalosome complex is conserved in fission yeast and has a role in S phase. Curr Biol (1999) 1.55
Samarium-153-EDTMP in bone metastases of hormone refractory prostate carcinoma: a phase I/II trial. J Nucl Med (1993) 1.55
Splitting the ATM: distinct repair and checkpoint defects in ataxia-telangiectasia. Trends Genet (1998) 1.52
Analysis of radiation-sensitive mutants of fission yeast. Methods Enzymol (1997) 1.50
Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis. Proc Natl Acad Sci U S A (2000) 1.46
Repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in the fission yeast Schizosaccharomyces pombe. Mol Microbiol (1993) 1.42
Toward validation of pain measurement tools for children: a pilot study. Pain (1993) 1.37
mik1+ encodes a tyrosine kinase that phosphorylates p34cdc2 on tyrosine 15. J Biol Chem (1994) 1.33
The 14-3-3 proteins encoded by the BMH1 and BMH2 genes are essential in the yeast Saccharomyces cerevisiae and can be replaced by a plant homologue. Eur J Biochem (1995) 1.33
Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function. Mol Gen Genet (1997) 1.33
Evidence for a subsurface ocean on Europa. Nature (1998) 1.28
The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells. Mol Biol Cell (1998) 1.25
S-phase and DNA-damage checkpoints: a tale of two yeasts. Curr Opin Cell Biol (1996) 1.23
DNA repair in the fission yeast, Schizosaccharomyces pombe. Mutat Res (1991) 1.23
The Wee1 protein kinase regulates T14 phosphorylation of fission yeast Cdc2. Mol Biol Cell (1995) 1.20
Cloning and characterisation of the Schizosaccharomyces pombe rad8 gene, a member of the SNF2 helicase family. Nucleic Acids Res (1993) 1.20
Nitrous oxide effects on cerebral evoked potential to pain: partial reversal with a narcotic antagonist. Anesthesiology (1979) 1.17
Ovarian steroid regulation of estrogen and progesterone receptor messenger ribonucleic acid in the anteroventral periventricular nucleus of the rat. J Neuroendocrinol (1996) 1.10
Aspirin analgesia evaluated by event-related potentials in man: possible central action in brain. Exp Brain Res (1980) 1.09
Molecular analysis of hus1+, a fission yeast gene required for S-M and DNA damage checkpoints. Mol Gen Genet (1997) 1.08
Pain and perception: comparison of sensory decision theory and evoked potential methods. Res Publ Assoc Res Nerv Ment Dis (1980) 1.07
Effect of nitrous oxide concentration on event-related potentials during painful tooth stimulation. Anesthesiology (1982) 1.05
The Schizosaccharomyces pombe rad11+ gene encodes the large subunit of replication protein A. Mol Cell Biol (1997) 1.05
Structure-function analysis of fission yeast Hus1-Rad1-Rad9 checkpoint complex. Mol Biol Cell (2001) 1.05
Brain evoked potentials are functional correlates of induced pain in man. Pain (1979) 1.04
Comparative effects of acupuncture and transcutaneous stimulation on the perception of painful dental stimuli. Pain (1976) 1.03
Evoked potentials as correlates of pain and pain relief in man. Agents Actions Suppl (1986) 1.00
The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer. Trends Genet (1995) 0.99
Clinical analgesic equivalence for morphine and hydromorphone with prolonged PCA. Pain (1996) 0.98
Cell-cycle checkpoints. Keeping mitosis in check. Curr Biol (1995) 0.98
Hydromorphone analgesia after intravenous bolus administration. Pain (1997) 0.97
Sum1, a highly conserved WD-repeat protein, suppresses S-M checkpoint mutants and inhibits the osmotic stress cell cycle response in fission yeast. Genetics (1998) 0.95
Psychological interventions for chronic pain: a critical review. I. Relaxation training and biofeedback. Pain (1982) 0.95
Effects of combining propofol and alfentanil on ventilation, analgesia, sedation, and emesis in human volunteers. Anesthesiology (1996) 0.95
Naloxone fails to reverse pain thresholds elevated by acupuncture: acupuncture analgesia reconsidered. Pain (1983) 0.94
Effects of diazepam on human pain tolerance and pain sensitivity. Psychosom Med (1973) 0.93
Steady-state infusions of opioids in human. II. Concentration-effect relationships and therapeutic margins. Pain (1990) 0.93
Assignment of ten DNA repair genes from Schizosaccharomyces pombe to chromosomal NotI restriction fragments. Mol Gen Genet (1991) 0.92
Use of patient-controlled analgesia for pain control for children receiving bone marrow transplant. J Pain Symptom Manage (1995) 0.92
Psychological interventions for chronic pain: a critical review. II. Operant conditioning, hypnosis, and cognitive-behavioral therapy. Pain (1982) 0.92
Use of gap repair in fission yeast to obtain novel alleles of specific genes. Nucleic Acids Res (1998) 0.92
Requirement of sequences outside the conserved kinase domain of fission yeast Rad3p for checkpoint control. Mol Biol Cell (1999) 0.91
Pain, depression, and illness behavior in a pain clinic population. Pain (1977) 0.90
Pain and the choice to hasten death in patients with painful metastatic cancer. J Palliat Care (1997) 0.90
Concentration-related effects of morphine on cognition and motor control in human subjects. Neuropsychopharmacology (1991) 0.90
Dental dolorimetry for human pain research: methods and apparatus. Pain (1979) 0.89
Effects of nitrous oxide, transcutaneous electrical stimulation, and their combination on brain potentials elicited by painful stimulation. Anesthesiology (1983) 0.88
Sensory decision theory methods in pain research: a reply to Rollman. Pain (1977) 0.88
The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast. DNA Repair (Amst) (2013) 0.88
Suppressors of cdc25p overexpression identify two pathways that influence the G2/M checkpoint in fission yeast. Genetics (1998) 0.88
Effects of intrasegmental electrical acupuncture on dental pain: evaluation by threshold estimation and sensory decision theory. Pain (1977) 0.87
Evoked potential assessment of acupunctural analgesia: attempted reversal with naloxone. Pain (1980) 0.87
Detection and decision factors in pain perception in young and elderly men. Pain (1976) 0.86
DNA structure-dependent checkpoints in model systems. Biol Chem (1997) 0.85
Letter: some pitfalls in the psychophysical assessment of drug effects: another look at the effects of diazepam on pain threshold. Br J Anaesth (1975) 0.85
Liz1p, a novel fission yeast membrane protein, is required for normal cell division when ribonucleotide reductase is inhibited. Mol Biol Cell (1999) 0.85
Checkpoint check. Nature (1993) 0.85