F H Gage

Author PubWeight™ 430.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996 28.95
2 Neurogenesis in the adult human hippocampus. Nat Med 1998 17.53
3 Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 1999 12.50
4 Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A 2000 10.88
5 More hippocampal neurons in adult mice living in an enriched environment. Nature 1997 10.06
6 Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 1996 9.84
7 Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A 1996 9.15
8 Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci U S A 1999 8.83
9 Vascular niche for adult hippocampal neurogenesis. J Comp Neurol 2000 7.19
10 Neural consequences of environmental enrichment. Nat Rev Neurosci 2000 6.79
11 A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 2009 6.62
12 Development of a self-inactivating lentivirus vector. J Virol 1998 6.60
13 Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 1997 4.92
14 Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat Genet 1997 4.26
15 The adult rat hippocampus contains primordial neural stem cells. Mol Cell Neurosci 1997 4.07
16 Experience-induced neurogenesis in the senescent dentate gyrus. J Neurosci 1998 3.71
17 Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. J Neurosci 1999 3.61
18 Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci 1997 3.61
19 Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci U S A 1997 3.40
20 Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J Neurosci 2000 3.40
21 Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J Virol 1997 3.37
22 Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proc Natl Acad Sci U S A 1997 2.96
23 Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol Psychiatry 2000 2.87
24 Regenerating the damaged central nervous system. Nature 2000 2.85
25 Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 2004 2.81
26 Nucleus basalis and thalamic control of neocortical activity in the freely moving rat. J Neurosci 1988 2.73
27 Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice. Nature 1998 2.72
28 Cell culture. Progenitor cells from human brain after death. Nature 2001 2.63
29 Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci U S A 2001 2.48
30 FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Mol Cell Neurosci 1995 2.45
31 Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature 1987 2.33
32 Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature 1996 2.33
33 The signal-dependent coactivator CBP is a nuclear target for pp90RSK. Cell 1996 2.26
34 Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. J Neurosci 2000 2.24
35 Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. Proc Natl Acad Sci U S A 2010 2.22
36 Adult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles. J Comp Neurol 1999 2.21
37 Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J Neurosci 1998 2.17
38 Can stem cells cross lineage boundaries? Nat Med 2001 2.08
39 Neuronal differentiation and morphological integration of hippocampal progenitor cells transplanted to the retina of immature and mature dystrophic rats. Mol Cell Neurosci 2000 2.07
40 Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J Neurosci 1997 2.07
41 Proliferation, differentiation, and long-term culture of primary hippocampal neurons. Proc Natl Acad Sci U S A 1993 2.00
42 Transcriptional profiling reveals strict boundaries between hippocampal subregions. J Comp Neurol 2001 1.98
43 Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J Neurobiol 1999 1.79
44 Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. Proc Natl Acad Sci U S A 1986 1.77
45 Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development 1999 1.73
46 Essential role of neocortical acetylcholine in spatial memory. Nature 1995 1.68
47 Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. Eur J Neurosci 2002 1.67
48 Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer. J Virol 1999 1.64
49 Widespread integration and survival of adult-derived neural progenitor cells in the developing optic retina. Mol Cell Neurosci 1998 1.62
50 Spatial learning and motor deficits in aged rats. Neurobiol Aging 1984 1.60
51 An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron 1998 1.58
52 Hippocampal connections and spatial discrimination. Brain Res 1978 1.54
53 Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations. Proc Natl Acad Sci U S A 1999 1.54
54 Environmental stimulation of 129/SvJ mice causes increased cell proliferation and neurogenesis in the adult dentate gyrus. Curr Biol 1998 1.51
55 FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor. Neuron 2000 1.50
56 A packaging cell line for lentivirus vectors. J Virol 1999 1.48
57 New nerve cells for the adult brain. Sci Am 1999 1.47
58 Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression. J Cell Biol 2001 1.42
59 Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science 1988 1.42
60 Nicotinic receptor-induced apoptotic cell death of hippocampal progenitor cells. J Neurosci 1998 1.42
61 Alzheimer's disease and spirochetes; a questionable relationship. Neuroreport 1993 1.41
62 Lentiviral vectors: regulated gene expression. Mol Ther 2000 1.39
63 Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes Dev 2001 1.35
64 Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proc Natl Acad Sci U S A 1996 1.35
65 Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol Dis 2010 1.35
66 Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors. Proc Natl Acad Sci U S A 1994 1.34
67 Activity-dependent regulation of neuronal plasticity and self repair. Prog Brain Res 2000 1.29
68 Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury. Exp Neurol 1996 1.26
69 FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord. Exp Neurol 1997 1.23
70 Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models. Exp Neurol 1999 1.23
71 Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal. Hippocampus 1999 1.22
72 Neurogenesis in the adult hippocampus. Novartis Found Symp 2000 1.18
73 Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. J Neurosci 1990 1.17
74 Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging. Neurobiol Aging 1992 1.17
75 Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Exp Neurol 1994 1.15
76 Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy. Proc Natl Acad Sci U S A 1999 1.14
77 Modeling psychiatric disorders at the cellular and network levels. Mol Psychiatry 2012 1.14
78 Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain Res 1991 1.11
79 An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model. Gene Ther 2004 1.10
80 Human amnion membrane serves as a substratum for growing axons in vitro and in vivo. Science 1987 1.10
81 Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats. J Neurosci 1984 1.10
82 Perforant path damage results in progressive neuronal death and somal atrophy in layer II of entorhinal cortex and functional impairment with increasing postdamage age. J Neurosci 1994 1.09
83 Synaptic loss in cognitively impaired aged rats is ameliorated by chronic human nerve growth factor infusion. Neuroscience 1995 1.07
84 NGF improves spatial memory in aged rodents as a function of age. J Neurosci 1991 1.06
85 Evidence for amelioration of ischaemic neuronal damage in the hippocampal formation by lesions of the perforant path. Neurol Res 1985 1.06
86 Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesion-induced degeneration. Exp Neurol 1999 1.06
87 Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration. Gene Ther 1996 1.05
88 Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat. Exp Neurol 1991 1.04
89 Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration. J Neurosci 1995 1.04
90 Grafting genetically modified cells into the rat brain: characteristics of E. coli beta-galactosidase as a reporter gene. Brain Res Mol Brain Res 1989 1.03
91 Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor. Neuron 1991 1.02
92 Petit mal epilepsy and parkinsonian tremor: hypothesis of a common pacemaker. Neuroscience 1990 1.02
93 Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain. Ann Neurol 1991 1.02
94 Spinal cord neuroblasts proliferate in response to basic fibroblast growth factor. J Neurosci 1994 1.02
95 Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology. J Neurosci 2004 1.02
96 NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat. Neuron 1989 1.02
97 Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell Transplant 1996 1.01
98 Nerve growth factor reverses neuronal atrophy in a Down syndrome model of age-related neurodegeneration. Neurology 1993 1.01
99 Morphological and neurochemical features of cultured primary skin fibroblasts of Fischer 344 rats following striatal implantation. J Comp Neurol 1992 1.01
100 Effects of gene transfer into cultured CNS neurons with a replication-defective herpes simplex virus type 1 vector. Brain Res Mol Brain Res 1992 1.00
101 Applications of gene therapy to the CNS. Hum Mol Genet 1996 1.00
102 Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum. Nature 1984 0.99
103 The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease. Mol Med Today 1999 0.99
104 Cross-species neural grafting in a rat model of Parkinson's disease. Nature 1982 0.98
105 Intraneuronal aggregate formation and cell death after viral expression of expanded polyglutamine tracts in the adult rat brain. J Neurosci 2000 0.98
106 Regulation of voltage- and ligand-gated currents in rat hippocampal progenitor cells in vitro. J Neurobiol 1997 0.97
107 Thymidine kinase-mediated killing of rat brain tumors. J Neurosurg 1993 0.97
108 Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery. Proc Natl Acad Sci U S A 1995 0.97
109 Neural grafting in a rat model of Huntington's disease: progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting. Neuroscience 1985 0.97
110 Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats. J Neurosci 1992 0.97
111 TrkA activation is sufficient to rescue axotomized cholinergic neurons. Neuron 1996 0.96
112 Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines. Brain Res 1992 0.96
113 Neuronal activity in the subcortically denervated hippocampus: a chronic model for epilepsy. Neuroscience 1989 0.95
114 Regulation of dopamine production by genetically modified primary fibroblasts. J Neurosci 1993 0.95
115 Gene therapy for neurologic disease. Arch Neurol 1993 0.95
116 Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor. Ann Neurol 1997 0.95
117 Morphologic alterations of choline acetyltransferase-positive neurons in the basal forebrain of aged behaviorally characterized Fisher 344 rats. Neurobiol Aging 1994 0.94
118 Intracerebral grafting of neuronal cell suspensions. III. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism. Acta Physiol Scand Suppl 1983 0.94
119 Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75. J Comp Neurol 1999 0.94
120 Cells of origin of the ventral cholinergic septohippocampal pathway undergoing compensatory collateral sprouting following fimbria-fornix transection. Neurosci Lett 1984 0.93
121 Dopaminergic cells align along radial glia in the developing mesencephalon of the rat. Neuroscience 1990 0.93
122 Spatial learning and memory following fimbria-fornix transection and grafting of fetal septal neurons to the hippocampus. Exp Brain Res 1987 0.93
123 Denervation releases a neuronal survival factor in adult rat hippocampus. Nature 1984 0.93
124 Reinnervation of the partially deafferented hippocampus by compensatory collateral sprouting from spared cholinergic and noradrenergic afferents. Brain Res 1983 0.92
125 Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-dopa. Neuron 1991 0.91
126 Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation. Acta Physiol Scand Suppl 1983 0.91
127 Repression of human fibroblast growth factor 2 by a novel transcription factor. J Biol Chem 1999 0.91
128 Generation and culturing of precursor cells and neuroblasts from embryonic and adult central nervous system. Methods Enzymol 1995 0.91
129 Potential use of nerve growth factor to treat Alzheimer's disease. Neurobiol Aging 1989 0.91
130 Cholinergic strategies for Alzheimer's disease. J Mol Med (Berl) 1998 0.90
131 Regeneration in the adult mammalian CNS: guided by development. Curr Opin Neurobiol 1995 0.90
132 Differential distribution of norepinephrine and serotonin along the dorsal-ventral axis of the hippocampal formation. Brain Res Bull 1981 0.90
133 A small-gauge cannula device for continuous infusion of exogenous agents into the brain. Exp Neurol 1987 0.90
134 Bcl-xL protects adult septal cholinergic neurons from axotomized cell death. Proc Natl Acad Sci U S A 1998 0.90
135 Retrovirus-mediated expression of an artificial beta-endorphin precursor in primary fibroblasts. J Neurochem 1995 0.89
136 Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome. Behav Neurosci 1991 0.89
137 Damage to hippocampus and hippocampal connections: effects on DRL and spontaneous alternation. J Comp Physiol Psychol 1977 0.89
138 High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor. Proc Natl Acad Sci U S A 1998 0.89
139 Bipotent progenitor cell lines from the human CNS. Nat Biotechnol 1997 0.89
140 In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis. Brain Res 1986 0.89
141 Cholinergic septal grafts into the hippocampal formation improve spatial learning and memory in aged rats by an atropine-sensitive mechanism. J Neurosci 1986 0.88
142 Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cell suspensions implanted in different brain sites. Acta Physiol Scand Suppl 1983 0.88
143 Fibroblast growth factor-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death. J Neurosci 1996 0.88
144 Mouse model of neurodegeneration: atrophy of basal forebrain cholinergic neurons in trisomy 16 transplants. Proc Natl Acad Sci U S A 1992 0.88
145 Spatial organization of physiological activity in the hippocampal region: relevance to memory formation. Prog Brain Res 1990 0.88
146 Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes. Brain Res 1991 0.87
147 Electric activity in the neocortex of freely moving young and aged rats. Neuroscience 1988 0.87
148 Retrograde cell changes in medial septum and diagonal band following fimbria-fornix transection: quantitative temporal analysis. Neuroscience 1986 0.87
149 The cholinergic nucleus basalis: a key structure in neocortical arousal. EXS 1989 0.87
150 Localization of hypoxanthine-guanine phosphoribosyltransferase mRNA in the mouse brain by in situ hybridization. Mol Cell Neurosci 1992 0.86
151 New tools for human developmental biology. Nat Biotechnol 2000 0.86
152 Electrophysiological characteristics of cells within mesencephalon suspension grafts. Neuroscience 1991 0.86
153 Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons. Exp Brain Res 1985 0.86
154 Intrahippocampal grafts of fetal basal forebrain tissue alter place fields in the hippocampus of rats with fimbria-fornix lesions. Neuroscience 1989 0.86
155 Expression of L1 and PSA during sprouting and regeneration in the adult hippocampal formation. J Comp Neurol 1998 0.86
156 Restoration of rhythmic slow activity (theta) in the subcortically denervated hippocampus by fetal CNS transplants. Brain Res 1987 0.86
157 Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats. Exp Neurol 2003 0.86
158 Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: response to fimbria-fornix transection. J Comp Neurol 1989 0.86
159 Suppression and induction of epileptic activity by neuronal grafts. Proc Natl Acad Sci U S A 1988 0.85
160 Grafting in the mammalian central nervous system. Physiol Rev 1993 0.85
161 Regional differences in responsiveness of adult CNS axons to grafts of cells expressing human neurotrophin 3. Exp Neurol 1995 0.85
162 Neurobiology of disease. Curr Opin Neurobiol 2000 0.85
163 Endogenous FGF-2 is important for cholinergic sprouting in the denervated hippocampus. J Neurosci 1997 0.85
164 Closer to neurogenesis in adult humans. Nat Med 1998 0.85
165 Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells. Brain Res 1986 0.84
166 Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats. Proc Natl Acad Sci U S A 1990 0.84
167 Cholinergic sprouting in the hippocampus: a proposed role for IL-1. Exp Neurol 1990 0.84
168 Behavioral dependence of the electrical activity of intracerebrally transplanted fetal hippocampus. Brain Res 1987 0.83
169 Emergence and propagation of interictal spikes in the subcortically denervated hippocampus. Hippocampus 1991 0.83
170 Enhanced graft survival in the hippocampus following selective denervation. Neuroscience 1986 0.83
171 Fibroblast growth factor-2-producing fibroblasts protect the nigrostriatal dopaminergic system from 6-hydroxydopamine. Brain Res 2000 0.83
172 Constitutive retinoid receptors expressed from adenovirus vectors that specifically activate chromosomal target genes required for differentiation of promyelocytic leukemia and teratocarcinoma cells. J Virol 1996 0.83
173 Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments. Brain Res 1990 0.83
174 Quantitative effects of cerebral infarction on spatial learning in rats. Exp Neurol 1992 0.83
175 Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies. J Comp Neurol 1994 0.83
176 A 10-amino acid sequence of fibroblast growth factor 2 is sufficient for its mitogenic activity on neural progenitor cells. Proc Natl Acad Sci U S A 1997 0.82
177 Hippocampal grafts into the intact brain induce epileptic patterns. Brain Res 1991 0.82
178 Spatial learning in rats: correlation with cortical choline acetyltransferase and improvement with NGF following NBM damage. Exp Neurol 1989 0.82
179 The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting. Brain Res 1986 0.82
180 Employment of fibroblasts for gene transfer: applications for grafting into the central nervous system. Genet Eng (N Y) 1991 0.82
181 Maintaining the neuronal phenotype after injury in the adult CNS. Neurotrophic factors, axonal growth substrates, and gene therapy. Mol Neurobiol 1995 0.82
182 Animal models of Lesch-Nyhan syndrome. Brain Res Bull 1990 0.82
183 Development of cholinergic neurons in the septal/diagonal band complex of the rat. Brain Res 1987 0.82
184 Intracerebral grafting of cultured autologous skin fibroblasts into the rat striatum: an assessment of graft size and ultrastructure. J Comp Neurol 1991 0.82
185 Gene transfer to the rodent placenta in situ. A new strategy for delivering gene products to the fetus. J Clin Invest 1998 0.82
186 Generation and analysis of GluR5(Q636R) kainate receptor mutant mice. J Neurosci 1999 0.82
187 Hippocampal grafts of acetylcholine-producing cells are sufficient to improve behavioural performance following a unilateral fimbria-fornix lesion. Neuroscience 1998 0.82
188 Cytokine regulation of nerve growth factor-mediated cholinergic neurotrophic activity synthesized by astrocytes and fibroblasts. J Neurochem 1992 0.82
189 Multisite recording of brain field potentials and unit activity in freely moving rats. J Neurosci Methods 1989 0.82
190 Basal forebrain cell loss following fimbria/fornix transection. Brain Res 1990 0.81
191 Neurotrophic factors and diseases of the nervous system. Ann Neurol 1994 0.81
192 Functional correlates of compensatory collateral sprouting by aminergic and cholinergic afferents in the hippocampal formation. Brain Res 1983 0.81
193 Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system. I. Grafts to the spinal cord. Exp Brain Res 1985 0.81
194 Cholinergic denervation-induced increase of chelatable zinc in mossy-fiber region of the hippocampal formation. Brain Res 1984 0.81
195 Motor enrichment sustains hindlimb movement recovered after spinal cord injury and glial transplantation. Restor Neurol Neurosci 2006 0.81
196 The grafted hippocampus: an epileptic focus. Exp Neurol 1989 0.81
197 Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection. Neuroscience 1990 0.81
198 Sonic hedgehog facilitates dopamine differentiation in the presence of a mesencephalic glial cell line. J Neurosci 2001 0.81
199 Cell suspension grafts of noradrenergic locus coeruleus neurons in rat hippocampus and spinal cord: reinnervation and transmitter turnover. Neuroscience 1986 0.81
200 Intrahippocampal septal grafts ameliorate learning impairments in aged rats. Science 1984 0.81
201 Differential expression of protein kinase C isozymes in rat glial cell cultures. Brain Res 1991 0.81
202 Neural grafting in a rat model of Huntington's disease: striosomal-like organization of striatal grafts as revealed by acetylcholinesterase histochemistry, immunocytochemistry and receptor autoradiography. Neuroscience 1987 0.81
203 Trophic and growth-regulating mechanisms in the central nervous system monitored by intracerebral neural transplants. Ciba Found Symp 1987 0.81
204 Enhanced survival and neuronal differentiation of adrenal chromaffin cells cografted into the striatum with NGF-producing fibroblasts. J Neurosci 1995 0.80
205 Cells engineered to produce acetylcholine: therapeutic potential for Alzheimer's disease. Ann N Y Acad Sci 1993 0.80
206 Intracerebral transplantation of dopamine neurons: understanding the functional role of the mesolimbocortical dopamine system and developing a therapy for Parkinson's disease. Ann N Y Acad Sci 1988 0.80
207 Cellular activity of intracerebrally transplanted fetal hippocampus during behavior. Neuroscience 1987 0.80
208 Cellular replacement therapy for neurologic disorders: potential of genetically engineered cells. J Cell Biochem 1991 0.80
209 Parkinson's disease. Fetal implants put to the test. Nature 1993 0.80
210 Chipping away at stem cells. Proc Natl Acad Sci U S A 2001 0.80
211 Structural plasticity: cause, result, or correlate of depression. Biol Psychiatry 2000 0.80
212 Intracerebral grafting of neuronal cell suspensions. VII. Recovery of choline acetyltransferase activity and acetylcholine synthesis in the denervated hippocampus reinnervated by septal suspension implants. Acta Physiol Scand Suppl 1983 0.80
213 Differential expression of protein kinase C isozymes in rat cerebellum. J Chem Neuroanat 1990 0.80
214 Response of septal cholinergic neurons to axotomy. J Comp Neurol 1987 0.80
215 Gene therapy in the central nervous system: the use of recombinant retroviruses. Arch Neurol 1999 0.79
216 Sprouting adult CNS cholinergic axons express NILE and associate with astrocytic surfaces expressing neural cell adhesion molecule. J Comp Neurol 1996 0.79
217 Storage, metabolism, and processing of 125I-fibroblast growth factor-2 after intracerebral injection. Brain Res 1994 0.79
218 Mechanisms of sprouting in the adult central nervous system: cellular responses in areas of terminal degeneration and reinnervation in the rat hippocampus. Neuroscience 1994 0.79
219 Radical directions in Parkinson's disease. Nat Med 1995 0.79
220 Novel therapeutic directions for Parkinson's disease. Mol Med Today 1995 0.79
221 Stem cell technology for basic science and clinical applications. Arch Neurol 1999 0.79
222 Transplanted septal neurons make viable cholinergic synapses with a host hippocampus. Brain Res 1985 0.78
223 Effects of choline and quiescence on Drosophila choline acetyltransferase expression and acetylcholine production by transduced rat fibroblasts. J Neurochem 1992 0.78
224 Intracerebral grafting of embryonic neural cells into the adult host brain: an overview of the cell suspension method and its application. Dev Neurosci 1984 0.78
225 Endogenous norepinephrine and serotonin within the hippocampal formation during the development and recovery from septal hyperreactivity. Pharmacol Biochem Behav 1978 0.78
226 Cholinergic neurons within the rat hippocampus: response to fimbria-fornix transection. J Comp Neurol 1988 0.78
227 Genome and gene therapy. Mol Ther 2000 0.78
228 In vivo production and release of acetylcholine from primary fibroblasts genetically modified to express choline acetyltransferase. J Neurochem 1993 0.78
229 Grafts of fetal septal cholinergic neurons to the hippocampal formation in aged or fimbria-fornix-lesioned rats. Ann N Y Acad Sci 1987 0.78
230 Effects of brain-derived neurotrophic factor and nerve growth factor on remaining neurons in the lesioned nucleus basalis magnocellularis. Brain Res 1994 0.78
231 Anticholinergic sensitivity in the aging rat septohippocampal system as assessed in a spatial memory task. Neurobiol Aging 1994 0.78
232 Age and damage induced changes in amyloid protein precursor immunohistochemistry in the rat brain. J Comp Neurol 1994 0.78
233 Grafting of nerve growth factor-producing fibroblasts reduces behavioral deficits in rats with lesions of the nucleus basalis magnocellularis. Neuroscience 1994 0.78
234 Gene transfer into established and primary fibroblast cell lines: comparison of transfection methods and promoters. Biotechniques 1992 0.78
235 Anatomical and functional consequences of grafting mesencephalic neurons into a peripheral nerve "bridge" connected to the denervated striatum. Exp Brain Res 1985 0.78
236 Development of the basal forebrain cholinergic system: phenotype expression prior to target innervation. Neurobiol Aging 1992 0.78
237 Portacaval shunt in the rat: selective alterations in behavior and brain serotonin. Pharmacol Biochem Behav 1986 0.77
238 Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease. Nat Med 1995 0.77
239 Modeling cholinergic abnormalities in Down syndrome and Alzheimer's disease. Prog Clin Biol Res 1991 0.77
240 Nucleus basalis lesions fail to induce senile plaques in the rat. Exp Neurol 1990 0.77
241 Application of ex vivo gene therapy in the treatment of Parkinson's disease. Exp Neurol 1997 0.77
242 Comparison of substance K-like and substance P-like fibers and cells in the rat hippocampus. Brain Res 1987 0.77
243 Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra. Exp Neurol 1991 0.77
244 Intracerebral grafting of neuronal cell suspensions. VI. Survival and growth of intrahippocampal implants of septal cell suspensions. Acta Physiol Scand Suppl 1983 0.77
245 Brain monoamine metabolism and behavior in portacaval-shunted rats. Exp Neurol 1985 0.77
246 Axonal regeneration and limited functional recovery following hippocampal deafferentation. J Comp Neurol 1995 0.77
247 The neurotrophic hypothesis and the cholinergic basal forebrain projection. Prog Brain Res 1993 0.77
248 Expression of biologically active basic fibroblast growth factor by genetically modified rat primary skin fibroblasts. J Neurochem 1995 0.77
249 Potential use of neurotrophic agents in the treatment of neurodegenerative disorders. Acta Neurobiol Exp (Wars) 1990 0.77
250 Intracerebral delivery of growth factors: potential application of genetically modified fibroblasts. Prog Growth Factor Res 1991 0.77
251 Enhanced detection of nucleus basalis magnocellularis lesion-induced spatial learning deficit in rats by modification of training regimen. Behav Brain Res 1989 0.77
252 Functional activity of raphe neurons transplanted to the hippocampus and caudate-putamen. An immunohistochemical and neurochemical analysis in adult and aged rats. Ann N Y Acad Sci 1987 0.76
253 Local regulation of compensatory noradrenergic hyperactivity in the partially denervated hippocampus. Nature 1983 0.76
254 Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75. Science 1997 0.76
255 Structural and functional analysis of raphe neurone implants into denervated rat spinal cord. Brain Res Bull 1989 0.76
256 Intracerebral transplantation: basic and clinical applications to the neostriatum. FASEB J 1994 0.76
257 Intracerebral grafting of neuronal cell suspensions. VIII. Survival and growth of implants of nigral and septal cell suspensions in intact brains of aged rats. Acta Physiol Scand Suppl 1983 0.76
258 Role of neurotrophic factors in Alzheimer's disease. Neurobiol Aging 1989 0.76
259 Behavioral assessment of norepinephrine and serotonin function and interaction in the hippocampal formation. Pharmacol Biochem Behav 1981 0.76
260 Adrenal chromaffin cells as multipotential neurons for autografts. Prog Brain Res 1990 0.76
261 Implantation of genetically engineered cells to the brain. Prog Brain Res 1988 0.76
262 Neural grafting in the aged rat brain. Annu Rev Physiol 1986 0.76
263 Dopamine-rich transplants in rats with 6-OHDA lesions of the ventral tegmental area. I. Effects on spontaneous and drug-induced locomotor activity. Behav Brain Res 1984 0.76
264 Brain-derived neurotrophic factor-transduced fibroblasts: production of BDNF and effects of grafting to the adult rat brain. J Comp Neurol 1995 0.76
265 Autocrine differentiation of PC12 cells mediated by retroviral vectors. Dev Neurosci 1990 0.76
266 Loss of GABAergic neurons in medial septum after fimbria-fornix transection. Neurosci Lett 1987 0.76
267 Long-term potentiation of evoked and spontaneous neuronal activity in the grafted hippocampus. Exp Brain Res 1989 0.76
268 Quantification of hippocampal noradrenaline and zinc changes after selective cell destruction. Exp Brain Res 1987 0.75
269 Intracerebral xenografts: Sertoli cells to the rescue? Nat Biotechnol 1996 0.75
270 Restoration and deterioration of function by brain grafts in the septohippocampal system. Prog Brain Res 1988 0.75
271 Normalization of subtype-specific muscarinic receptor binding in the denervated hippocampus by septodiagonal band grafts. Exp Neurol 1989 0.75
272 Inhibition of synaptosomal neurotransmitter uptake by hallucinogens. J Neurochem 1983 0.75
273 Restoration of function to the denervated spinal cord after implantation of embryonic 5HT- and substance P-containing raphe neurones. Prog Brain Res 1990 0.75
274 Brain transplants: can they restore single unit activity in the hippocampus? Ann N Y Acad Sci 1985 0.75
275 Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system. II. Grafts to the hippocampus. Exp Brain Res 1988 0.75
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