Published in Nat Genet on December 01, 1997
ATM and ataxia telangiectasia. EMBO Rep (2004) 2.31
Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans. Chromosoma (2003) 2.29
AtATM is essential for meiosis and the somatic response to DNA damage in plants. Plant Cell (2003) 1.92
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Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proc Natl Acad Sci U S A (1999) 1.57
Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice. Mol Cell Biol (1998) 1.49
Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta (2006) 1.41
Atm inactivation results in aberrant telomere clustering during meiotic prophase. Mol Cell Biol (1999) 1.22
Meiotic telomere distribution and Sertoli cell nuclear architecture are altered in Atm- and Atm-p53-deficient mice. Mol Cell Biol (2000) 1.19
The ATM signaling network in development and disease. Front Genet (2013) 1.09
Identification of morc (microrchidia), a mutation that results in arrest of spermatogenesis at an early meiotic stage in the mouse. Proc Natl Acad Sci U S A (1998) 1.02
ATM specifically mediates repair of double-strand breaks with blocked DNA ends. Nat Commun (2014) 0.97
Mammalian meiosis involves DNA double-strand breaks with 3' overhangs. Chromosoma (2003) 0.89
ATM to the rescue: repairing DNA damage. Plant Cell (2003) 0.80
Programmed cell death may act as a surveillance mechanism to safeguard male gametophyte development in Arabidopsis. Protein Cell (2011) 0.79
Recent progress in mouse models for tumor suppressor genes and its implications in human cancer. Clin Med Insights Oncol (2013) 0.78
A novel genetic modifier of p53, mop1, results in embryonic lethality. Mamm Genome (2004) 0.77
A role for c-Abl in cell senescence and spontaneous immortalization. Age (Dordr) (2012) 0.75
MicroRNA profiling of tacrolimus-stimulated Jurkat human T lympocytes. J Korean Surg Soc (2013) 0.75
p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes. PLoS Genet (2017) 0.75
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Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol Cell (1999) 5.28
Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology (Berl) (1997) 5.03
Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res (1997) 4.89
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DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation. Nature (2000) 4.10
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Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4. J Biol Chem (2000) 3.37
TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J Cell Biol (2001) 3.22
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development (1998) 3.21
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Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase. J Biol Chem (1999) 3.17
Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature (1998) 3.16
Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat Genet (1997) 3.11
Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell (1997) 3.10
Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping. Cancer Res (1999) 3.06
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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature (1997) 2.98
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Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat Genet (2001) 2.82
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Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat Cell Biol (2000) 2.81
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Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc Natl Acad Sci U S A (2000) 2.49
A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability. Oncogene (1998) 2.39
Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean. Nature (2001) 2.39
Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood (1998) 2.36
Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5. Development (1999) 2.34
Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice. Oncogene (2001) 2.33
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Aberrant nuclear behavior at meiosis and anucleate spore formation by sporulation-deficient (SPO) mutants of Saccharomyces cerevisiae. Exp Cell Res (1974) 2.27
Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice. Blood (2000) 2.16
Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proc Natl Acad Sci U S A (1997) 2.14
Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q. Genes Chromosomes Cancer (1997) 2.06
Activation of the c-Raf protein kinase by protein kinase C phosphorylation. Oncogene (1992) 2.04
The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues. Nat Genet (1995) 2.02
An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction. Immunity (1997) 2.01
Mesenchymal stem cell as salvage treatment for refractory chronic GVHD. Bone Marrow Transplant (2010) 2.00
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Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. Proc Natl Acad Sci U S A (1998) 1.94
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Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice. J Biol Chem (1988) 1.91
Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung. Cancer Res (1997) 1.89
Chromosome number of a small protist: accurate determination. Science (1969) 1.87
Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice. Proc Natl Acad Sci U S A (2001) 1.87
Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. Cell (1996) 1.84
Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X chromosome territories have similar volumes but differ in shape and surface structure. J Cell Biol (1996) 1.82
Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I. Development (1998) 1.81
RAD51 and DMC1 form mixed complexes associated with mouse meiotic chromosome cores and synaptonemal complexes. J Cell Biol (1999) 1.81
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. Nat Genet (1997) 1.76
Activation of rat brain phospholipase D by ADP-ribosylation factors 1,5, and 6: separation of ADP-ribosylation factor-dependent and oleate-dependent enzymes. Proc Natl Acad Sci U S A (1994) 1.74
Quantitative analysis of comparative genomic hybridization. Cytometry (1995) 1.72
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors. Hum Mol Genet (1999) 1.72
Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion. Dev Biol (2001) 1.71
Basic fibroblast growth factor positively regulates hematopoietic development. Development (2000) 1.67
Direct removal in the mouse of a floxed neo gene from a three-loxP conditional knockout allele by two novel approaches. Genesis (2001) 1.67
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Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis. J Clin Invest (1999) 1.62
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