Published in EMBO J on June 01, 1998
HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell (2003) 9.12
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol (2003) 8.12
HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell (2008) 8.01
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol Cell Biol (2005) 6.44
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer (2011) 6.32
HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell (2007) 6.16
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature (2008) 6.13
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol (2001) 5.59
Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest (2005) 5.53
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol (2000) 5.21
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev (2000) 5.16
HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev (2006) 5.15
Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth. PLoS Biol (2003) 5.14
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell (2010) 5.07
SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell (2007) 4.46
Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev (2007) 4.46
Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev (2001) 4.45
The role of oxygen availability in embryonic development and stem cell function. Nat Rev Mol Cell Biol (2008) 4.43
The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ (2008) 4.31
Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev (2000) 4.24
The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes Dev (2007) 4.13
HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation. Cancer Cell (2007) 4.10
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. Mol Cell Biol (2001) 4.03
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha. J Clin Invest (1999) 4.00
Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. Biochem J (2008) 3.98
Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. J Clin Invest (2004) 3.90
Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J (1999) 3.70
Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. J Clin Invest (2007) 3.61
Acute postnatal ablation of Hif-2alpha results in anemia. Proc Natl Acad Sci U S A (2007) 3.51
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol Cell Biol (2007) 3.51
Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha. Genes Dev (2001) 3.39
Interdependence of hypoxic and innate immune responses. Nat Rev Immunol (2009) 3.29
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression. Genes Dev (2002) 3.16
Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT. EMBO J (1998) 3.13
The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling. Proc Natl Acad Sci U S A (2000) 3.12
Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. Mol Cell Biol (2003) 3.10
RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha. Mol Cell (2007) 3.09
MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res (2009) 2.93
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci U S A (2001) 2.77
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol (2004) 2.74
Activating transcription factor 4 is translationally regulated by hypoxic stress. Mol Cell Biol (2004) 2.68
Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia. Am J Pathol (2000) 2.61
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2. Mol Cell Biol (2006) 2.58
Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3) J Clin Invest (2000) 2.57
Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia. Blood (2010) 2.57
Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Mol Cell Biol (2006) 2.56
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure. Blood (2007) 2.51
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc Natl Acad Sci U S A (2010) 2.49
HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice. J Clin Invest (2009) 2.47
The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia. Proc Natl Acad Sci U S A (2001) 2.45
O2 regulates stem cells through Wnt/β-catenin signalling. Nat Cell Biol (2010) 2.45
Signaling mechanisms of the epithelial-mesenchymal transition. Sci Signal (2014) 2.42
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control. EMBO J (2006) 2.41
Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype. Proc Natl Acad Sci U S A (2002) 2.39
HIF1alpha delays premature senescence through the activation of MIF. Genes Dev (2006) 2.37
Expression of vascular endothelial growth factor, hypoxia inducible factor 1alpha, and carbonic anhydrase IX in human tumours. J Clin Pathol (2004) 2.36
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha. Proc Natl Acad Sci U S A (2002) 2.35
Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. Genes Dev (2000) 2.32
Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma. Am J Pathol (2003) 2.30
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling. Cardiovasc Res (2010) 2.30
HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin. EMBO J (2003) 2.28
Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. Genes Dev (2010) 2.26
The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO. Cell (2012) 2.25
Hypoxia-inducible factors in the kidney. Am J Physiol Renal Physiol (2006) 2.25
HIF-1 mediates the Warburg effect in clear cell renal carcinoma. J Bioenerg Biomembr (2007) 2.00
Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha. Mol Cell Biol (2003) 1.99
Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Mol Cell Biol (2005) 1.97
Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature. Mol Cell Biol (2000) 1.95
CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex. J Biol Chem (2008) 1.93
The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo. Mol Cell Biol (2007) 1.92
PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). Proc Natl Acad Sci U S A (2008) 1.92
Multilineage embryonic hematopoiesis requires hypoxic ARNT activity. Genes Dev (1999) 1.92
Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1. J Clin Invest (2000) 1.89
Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen. Nat Immunol (2013) 1.86
Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth. Cancer Cell (2003) 1.85
Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar. Mol Cell Biol (2002) 1.83
Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc Natl Acad Sci U S A (2000) 1.82
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell (2009) 1.82
Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases. Cold Spring Harb Symp Quant Biol (2011) 1.81
Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance. Mol Cell Biol (2004) 1.77
Hypoxic regulation of erythropoiesis and iron metabolism. Am J Physiol Renal Physiol (2010) 1.76
Generating specificity and diversity in the transcriptional response to hypoxia. Nat Rev Genet (2009) 1.76
Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Mol Cell Biol (2003) 1.75
Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival. J Clin Invest (2004) 1.72
Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. J Clin Invest (2010) 1.70
HIF and the lung: role of hypoxia-inducible factors in pulmonary development and disease. Am J Respir Crit Care Med (2011) 1.68
Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF. J Bone Miner Res (2009) 1.68
Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP. Mol Cell Biol (2002) 1.67
Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation. Mol Cell Biol (2005) 1.67
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT). Mol Cell Biol (2004) 1.65
The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc Natl Acad Sci U S A (2002) 1.64
A twist of insight - the role of Twist-family bHLH factors in development. Int J Dev Biol (2009) 1.62
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice. Mol Cell Biol (2008) 1.62
Bioluminescence imaging: progress and applications. Trends Biotechnol (2011) 1.59
The SirT3 divining rod points to oxidative stress. Mol Cell (2011) 1.58
HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia. Cell (2013) 1.58
Passing the baton: the HIF switch. Trends Biochem Sci (2012) 1.58
Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes. Curr Opin Genet Dev (2009) 1.57
Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer. Breast Cancer Res (2012) 1.55
Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis. Mol Cell Biol (2003) 1.54
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A (1995) 24.77
RAG-1-deficient mice have no mature B and T lymphocytes. Cell (1992) 20.97
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature (1996) 18.47
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature (1992) 18.26
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature (1996) 16.92
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol (1996) 15.20
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol (1992) 11.03
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature (1996) 10.14
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem (1994) 9.21
Purification and characterization of hypoxia-inducible factor 1. J Biol Chem (1995) 8.53
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev (1997) 8.51
Production of homozygous mutant ES cells with a single targeting construct. Mol Cell Biol (1992) 7.23
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci U S A (1993) 6.77
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci U S A (1997) 6.11
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science (1995) 6.03
Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev (1996) 5.44
Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem (1995) 5.20
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J Biol Chem (1993) 5.09
Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci (1995) 4.97
Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene. Proc Natl Acad Sci U S A (1991) 4.84
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proc Natl Acad Sci U S A (1996) 4.66
Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer. Circ Res (1995) 4.55
Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature (1997) 4.36
Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J Biol Chem (1996) 3.80
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem (1995) 3.69
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J Biol Chem (1997) 3.67
Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases. Lab Invest (1995) 3.25
Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis. Cardiovasc Res (1994) 2.91
Vascular endothelial cell lineage-specific promoter in transgenic mice. Development (1995) 2.76
cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt). Mol Cell Biol (1996) 2.42
The AH-receptor: genetics, structure and function. Pharmacogenetics (1993) 2.41
Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability. FEBS Lett (1995) 2.31
Aryl hydrocarbon receptor-mediated signal transduction. Crit Rev Toxicol (1997) 2.00
Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts. Cancer Res (1993) 1.97
Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart. Biochem Biophys Res Commun (1993) 1.93
Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor. Biochem Biophys Res Commun (1995) 1.87
Targeting gene expression to hypoxic tumor cells. Nat Med (1997) 1.82
Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms. Cancer Res (1997) 1.70
Tumour hypoxia: the picture has changed in the 1990s. Int J Radiat Biol (1994) 1.38
Vascular permeability factor expression influences tumor angiogenesis in human melanoma lines xenografted to nude mice. Am J Pathol (1995) 1.33
Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts. Int J Cancer (1996) 1.20
Oxygen- and dioxin-regulated gene expression in mouse hepatoma cells. Kidney Int (1997) 1.11
Abundant expression of GLUT1 and GLUT3 in rat embryo during the early organogenesis period. Biochem Biophys Res Commun (1995) 1.08
Glucose absorption and utilization by rat embryos. Int J Dev Biol (1997) 1.03
Glucose metabolism in separated embryos and investing membranes during organogenesis in the rat. Metabolism (1994) 1.00
Inhibitors of glycolytic metabolism affect neurulation-staged mouse conceptuses in vitro. Teratology (1995) 0.95
RAG-1-deficient mice have no mature B and T lymphocytes. Cell (1992) 20.97
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature (1997) 10.14
An essential role for ectodomain shedding in mammalian development. Science (1998) 9.14
Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. Science (1991) 7.25
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature (1994) 6.50
Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci U S A (1999) 6.34
Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth. Cancer Res (2000) 6.14
Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science (1996) 4.61
Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev (2001) 4.45
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J (1997) 4.28
Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev (2000) 4.24
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. Mol Cell Biol (2001) 4.03
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor. J Biol Chem (1998) 3.83
c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J (1999) 3.65
Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha. Genes Dev (2001) 3.39
Biology of HIF-1alpha. Cell Death Differ (2008) 3.24
Sequence database searches via de novo peptide sequencing by tandem mass spectrometry. Rapid Commun Mass Spectrom (1997) 3.03
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol Cell (2000) 2.70
Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein. Neuron (1994) 2.47
HOMOLOGOUS ANTIPNEUMOCOCCAL SERUMS IN THE TREATMENT OF LOBAR PNEUMONIA. Br Med J (1931) 2.20
Mice lacking major histocompatibility complex class I and class II molecules. Proc Natl Acad Sci U S A (1993) 2.18
Novel fragmentation process of peptides by collision-induced decomposition in a tandem mass spectrometer: differentiation of leucine and isoleucine. Anal Chem (1987) 2.10
Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity (2000) 2.05
Implementation and uses of automated de novo peptide sequencing by tandem mass spectrometry. Anal Chem (2001) 2.05
Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Res (1999) 2.05
Putting a price on biotechnology. Nat Biotechnol (2001) 2.01
Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A (1997) 1.97
Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature. Mol Cell Biol (2000) 1.95
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E. Nat Genet (1999) 1.76
Functional domains of the ClpA and ClpX molecular chaperones identified by limited proteolysis and deletion analysis. J Biol Chem (2001) 1.68
Biochemical characterization of endogenously formed eosinophilic crystals in the lungs of mice. J Biol Chem (2000) 1.67
Determination of v-Mos-catalyzed phosphorylation sites and autophosphorylation sites on MAP kinase kinase by ESI/MS. Biochemistry (1995) 1.52
The rod transducin alpha subunit amino terminus is heterogeneously fatty acylated. J Biol Chem (1992) 1.40
SPARC is a source of copper-binding peptides that stimulate angiogenesis. J Cell Biol (1994) 1.40
Targeted disruption of CD43 gene enhances T lymphocyte adhesion. J Immunol (1993) 1.37
Isolation and characterisation of bacteria from abscesses in the subcutis of cats. J Med Microbiol (1979) 1.34
Mixed conformations of deoxyribonucleic acid in intact chromatin isolated by various preparative methods. Biochemistry (1972) 1.30
c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation. J Cell Biol (2002) 1.28
Angiogenesis: the role of the microenvironment in flipping the switch. Curr Opin Genet Dev (2001) 1.27
Topographic study of arrestin using differential chemical modifications and hydrogen/deuterium exchange. Protein Sci (1994) 1.26
Growth and differentiation of embryonic stem cells that lack an intact c-fos gene. Proc Natl Acad Sci U S A (1992) 1.25
Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes Dev (2001) 1.24
Sequential phosphorylation of rhodopsin at multiple sites. Biochemistry (1993) 1.23
The NH2 terminus of retinal recoverin is acylated by a small family of fatty acids. J Biol Chem (1992) 1.19
Loss of vascular endothelial growth factor expression reduces vascularization, but not growth, of tumors lacking the Von Hippel-Lindau tumor suppressor gene. Oncogene (2007) 1.18
Characterization of a truncated form of arrestin isolated from bovine rod outer segments. Protein Sci (1994) 1.16
Characterization of the glycosylation sites in yeast external invertase. I. N-linked oligosaccharide content of the individual sequons. J Biol Chem (1988) 1.15
Mixed conformations of deoxyribonucleic acid in chromatin: a preliminary report. Proc Natl Acad Sci U S A (1972) 1.12
Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific and South East Asian regions, 2007-2008. Commun Dis Intell Q Rep (2010) 1.11
Ischaemia-induced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Müller cells. Diabetologia (2011) 1.08
The primary structure of thioredoxin from Chromatium vinosum determined by high-performance tandem mass spectrometry. Biochemistry (1987) 1.07
Isolation and characterisation of bacteria from pyothorax (empyaemia) in cats. Vet Microbiol (1982) 1.07
Null mutation of c-fos impairs structural and functional plasticities in the kindling model of epilepsy. J Neurosci (1996) 1.06
Normal peripheral T-cell function in c-Fos-deficient mice. Mol Cell Biol (1994) 1.06
Glutaredoxin from rabbit bone marrow. Purification, characterization, and amino acid sequence determined by tandem mass spectrometry. J Biol Chem (1989) 1.06
The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles. J Virol (2008) 1.03
Facial soft tissue response to anterior segmental osteotomies: a systematic review. Int J Oral Maxillofac Surg (2010) 1.03
Retroperitoneal ancient schwannoma: review of clinico-radiological features. Australas Radiol (1998) 1.02
A blood isolate of Neisseria meningitidis showing reduced susceptibility to quinolones in Hong Kong. Int J Antimicrob Agents (2007) 1.00
Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent. Osteoarthritis Cartilage (2004) 0.98
Sherpa: a Macintosh-based expert system for the interpretation of electrospray ionization LC/MS and MS/MS data from protein digests. Rapid Commun Mass Spectrom (1996) 0.98
Control of rhodopsin multiple phosphorylation. Biochemistry (1994) 0.97
Characterization of protease processing sites during conversion of rat profilaggrin to filaggrin. Biochemistry (1993) 0.97
A cytogenetic study of 77 Chinese children with Down's syndrom. J Ment Defic Res (1967) 0.96
Behavioral assessment of c-fos mutant mice. Brain Res (1994) 0.95
Management of a ruptured pseudoaneurysm of the sphenopalatine artery following a Le Fort I osteotomy. J Oral Maxillofac Surg (1987) 0.95
Protein adsorption on hydrogels. II. Reversible and irreversible interactions between lysozyme and soft contact lens surfaces. Biomaterials (1985) 0.94
Modes of photodynamic vs. sonodynamic cytotoxicity. J Photochem Photobiol B (1995) 0.92
Relationship between protein and DNA structure in calf thymus chromatin. II. Conformational aspects. Biochemistry (1974) 0.92
Relaxation for insomnia and hypnotic medication use in older women. Psychol Aging (1993) 0.91
Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-alpha (TNF-alpha) production suggest the major TNF-alpha converting enzyme is not an MMP. Biochem Biophys Res Commun (1996) 0.90
Aggressive thoracic actinomycosis complicated by vertebral osteomyelitis and epidural abscess leading to spinal cord compression. Spine (Phila Pa 1976) (2000) 0.89
Interferon: cloudy but intriguing future. JAMA (1981) 0.87
Tumour oxygenation: implications for breast cancer prognosis. J Intern Med (2013) 0.87
Communication between catalytic and regulatory subunits in Ni(II)- and Co(II)-aspartate transcarbamoylase. Ligand-promoted structural alterations at the intersubunit bonding domains. J Biol Chem (1983) 0.87
Effect of a null mutation of the c-fos proto-oncogene on sexual behavior of male mice. Biol Reprod (1994) 0.87
Purification and properties of sphingolipid beta-galactosidases from human placenta. J Biol Chem (1979) 0.87
Rapid skin edge elevation using the OCT compound droplet technique to obtain horizontal microsections in Mohs micrographic surgery. J Dermatol Surg Oncol (1991) 0.86
Autoantibodies and associated T-cell responses to determinants within the 831-860 region of the autoantigen IA-2 in Type 1 diabetes. J Autoimmun (2009) 0.86
Mass spectrometrically derived amino acid sequence of thioredoxin from Chlorobium, an evolutionarily prominent photosynthetic bacterium. J Biol Chem (1987) 0.86
Delineation of an immunodominant and human T-cell lymphotropic virus (HTLV)-specific epitope within the HTLV-I transmembrane glycoprotein. Blood (1995) 0.86
Mass spectrometric analysis of 21 phosphorylation sites in the internal repeat of rat profilaggrin, precursor of an intermediate filament associated protein. Biochemistry (1995) 0.86
Monitoring calcium-induced conformational changes in recoverin by electrospray mass spectrometry. Protein Sci (1997) 0.85
Altered matrix metalloproteinase expression associated with oncogene-mediated cellular transformation and metastasis formation. Cell Biol Int (2001) 0.85
TREATMENT OF LOBAR PNEUMONIA BY ANTI-PNEUMOCOCCAL SERUM. Br Med J (1932) 0.84
Propagation of conformational changes in Ni(II)-substituted aspartate transcarbamoylase: effect of active-site ligands on the regulatory chains. Proc Natl Acad Sci U S A (1980) 0.83
Initial two-year results of the Oregon Liver Transplantation Program. Am J Surg (1991) 0.83
Characterization of protein adsorption on soft contact lenses. I. Conformational changes of adsorbed human serum albumin. Biomaterials (1984) 0.83
Is weight gain after smoking cessation inevitable? J Consult Clin Psychol (1995) 0.83
Are postoperative intravenous antibiotics necessary after bimaxillary orthognathic surgery? A prospective, randomized, double-blind, placebo-controlled clinical trial. Int J Oral Maxillofac Surg (2011) 0.82
High-pressure gel loader for capillary array electrophoresis microchannel plates. Biotechniques (2001) 0.82
The circadian system of c-fos deficient mice. J Comp Physiol A (1996) 0.81
Familial canine dermatomyositis: clinical, electrodiagnostic, and genetic studies. Am J Vet Res (1985) 0.80
Relationship between protein and DNA structure in calf thymus chromatin. I. Compositional aspects. Biochemistry (1974) 0.80
Are insomniacs sleepy during the day? A pupillometric assessment. Behav Res Ther (1992) 0.80
Prone table stereotactic breast biopsy. Hong Kong Med J (2002) 0.79
Sterilization failures with bipolar tubal cautery. Fertil Steril (1984) 0.79
An improved blood culture medium. Med Lab Technol (1974) 0.79
The development of a maternal satisfaction scale for caesarean section. Int J Obstet Anesth (1999) 0.79